The first example of meso-aziridine desymmetrization with selenium nucleophiles is reported. The reaction, promoted by VAPOL-hydrogen phosphate using (phenylseleno)trimethylsilane as the nucleophile, proves to be very general and highly enantioselective (84-99% ee).

A general phosphoric acid-catalyzed desymmetrization of meso-aziridines with silylated selenium nucleophiles

SANTORO, STEFANO;SANTI, Claudio;
2011

Abstract

The first example of meso-aziridine desymmetrization with selenium nucleophiles is reported. The reaction, promoted by VAPOL-hydrogen phosphate using (phenylseleno)trimethylsilane as the nucleophile, proves to be very general and highly enantioselective (84-99% ee).
2011
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11391/374694
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