In this study we describe some biological effects of IL-34, a newly discovered cytokine. We show that 11-34 stimulates monocyte cell viability and directly modulates the number and function of monocytes and regulates myeloid cell growth and differentiation. Moreover, since IL-34 in mice is involved in osteoporosis, an antagonist of this cytokine could be beneficial for the treatment of this disease.
IL-34 a newly discovered cytokine
CARAFFA, Auro;ANTINOLFI, PIERLUIGI;
2010
Abstract
In this study we describe some biological effects of IL-34, a newly discovered cytokine. We show that 11-34 stimulates monocyte cell viability and directly modulates the number and function of monocytes and regulates myeloid cell growth and differentiation. Moreover, since IL-34 in mice is involved in osteoporosis, an antagonist of this cytokine could be beneficial for the treatment of this disease.File in questo prodotto:
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