Adverse reactions to systemic drugs rarely may be due to vehicle components, such as preservatives, colorants and antioxidants. We report the case of a 44-year-old woman affected by localized pustulosis of the chin, neck and V of the chest, appeared after 2 days of intramuscular therapy with diclofenac. The patch test showed positive reaction to the drug as it and to sodium metabisulphite (5% pet). Sodium metabisulphite is an antioxidant mainly used in the food industry. However, it is present in some parenteral drugs, such as local anesthetics with adrenaline, diclofenac, and corticosteroids.
Pustolosi acuta localizzata da sodio metabisolfito
BIANCHI, LEONARDO;LANZA, FRANCESCO;LISI, Paolo
2011
Abstract
Adverse reactions to systemic drugs rarely may be due to vehicle components, such as preservatives, colorants and antioxidants. We report the case of a 44-year-old woman affected by localized pustulosis of the chin, neck and V of the chest, appeared after 2 days of intramuscular therapy with diclofenac. The patch test showed positive reaction to the drug as it and to sodium metabisulphite (5% pet). Sodium metabisulphite is an antioxidant mainly used in the food industry. However, it is present in some parenteral drugs, such as local anesthetics with adrenaline, diclofenac, and corticosteroids.File in questo prodotto:
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