The incubation of skeletal muscle in the presence of theophylline and Imidazole causes an increase in cyclic AMP levels while it has no effect on cyclic GMP concentration. Tetanic stimulation does not change the levels of the cyclic nucleotides being measured at the end of stimulation in muscles treated with normal Ringer solution or in the presence od Theophylline. In the presence of Imidazole, there is a further increase in cyclic AMP levels. An inverse correlation between cyclic AMP concentration and the amount of isotonic contraction has been demonstrated.
Effect of theophilline and imidazole on cyclic AMP and cyclic GMP levels in active sartorius muscle of Rana esculenta
PRINCIPATO, Giovanni Battista;ORLACCHIO, Aldo
1981
Abstract
The incubation of skeletal muscle in the presence of theophylline and Imidazole causes an increase in cyclic AMP levels while it has no effect on cyclic GMP concentration. Tetanic stimulation does not change the levels of the cyclic nucleotides being measured at the end of stimulation in muscles treated with normal Ringer solution or in the presence od Theophylline. In the presence of Imidazole, there is a further increase in cyclic AMP levels. An inverse correlation between cyclic AMP concentration and the amount of isotonic contraction has been demonstrated.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
