Ganglioneuromas are usually considered not to be functionally active. Studies on their catecholamine excretory pattern and of their imaging by means of the adrenergic tracing agent 131-I-MIBG have been therefore sparse. We report on a case of secretory ganglioneuroma, as demonstrated by the increased urinary excretion of the catecholamine metabolites HVA and VMA, increased plasma dopamine and epinephrine levels, and positive 131-I-MIBG scintigraphy. We must therefore be aware that a functionally active tumor is not necessarily a neuroblastoma, and that the diagnosis should be biopsy proven.

Functionally Active Ganglioneuroma With Increased Plasma and Urinary Catecholamines and Positive Iodine 131-Meta-Iodobenzylguanidine Scintigraphy

CODINI, Michela
1991

Abstract

Ganglioneuromas are usually considered not to be functionally active. Studies on their catecholamine excretory pattern and of their imaging by means of the adrenergic tracing agent 131-I-MIBG have been therefore sparse. We report on a case of secretory ganglioneuroma, as demonstrated by the increased urinary excretion of the catecholamine metabolites HVA and VMA, increased plasma dopamine and epinephrine levels, and positive 131-I-MIBG scintigraphy. We must therefore be aware that a functionally active tumor is not necessarily a neuroblastoma, and that the diagnosis should be biopsy proven.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11391/918928
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