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EnglishSpecific cytotoxic T cells were obtained by coculturing "in vitro" normal spleen cells with inactivated histocompatible DTIC-altered lymphoma cells. The "in vivo" antitumor activity of such sensitized lymphocytes was evaluated by injecting a mixture of lymphocytes + tumor into the brains of lethally irradiated syngenic mice. The results indicated that such lymphocytes demonstrate antitumor activity against the same tumor but not against unrelated tumors.
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| Titolo: | [Transfer in vivo of cytotoxic immune lymphocytes obtained in vitro in primary culture against a murine lymphoma antigenically altered by DTIC]. |
| Autori: | |
| Data di pubblicazione: | 1979 |
| Rivista: | |
| Abstract: | Specific cytotoxic T cells were obtained by coculturing "in vitro" normal spleen cells with inact...ivated histocompatible DTIC-altered lymphoma cells. The "in vivo" antitumor activity of such sensitized lymphocytes was evaluated by injecting a mixture of lymphocytes + tumor into the brains of lethally irradiated syngenic mice. The results indicated that such lymphocytes demonstrate antitumor activity against the same tumor but not against unrelated tumors. |
| Handle: | http://hdl.handle.net/11391/923272 |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
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