Sfoglia per Autore
Enantioresolution, stereochemical characterization and biological activity of a chiral large-conductance calcium-activated potassium channel opener.
2014 Sardella, Roccaldo; Carotti, Andrea; Manfroni, Giuseppe; Tedesco, D; Martelli, A; Bertucci, C; Cecchetti, Violetta; Natalini, Benedetto
Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization
2015 Astolfi, Andrea; Barreca, MARIA LETIZIA; Iraci, Nunzio; Cannalire, Rolando; Sabatini, Stefano; Manfroni, Giuseppe; Cecchetti, Violetta
A Broad Anti-influenza Hybrid Small Molecule that Potently Disrupts the Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits Interaction
2015 Massari, Serena; Nannetti, Giulio; Desantis, Jenny; Muratore, Giulia; Sabatini, Stefano; Manfroni, Giuseppe; Mercorelli, Beatrice; Cecchetti, Violetta; Palù, Giorgio; Cruciani, Gabriele; Loregian, Arianna; Goracci, Laura; Tabarrini, Oriana
A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors
2015 Astolfi, Andrea; Iraci, Nunzio; Manfroni, Giuseppe; Barreca, MARIA LETIZIA; Cecchetti, Violetta
Boosting Effect of 2-Phenylquinoline Efflux Inhibitors in Combination with Macrolides against Mycobacterium smegmatis and Mycobacterium avium
2015 Machado, Diana; Cannalire, Rolando; Santos Costa, Sofia; Manfroni, Giuseppe; Tabarrini, Oriana; Cecchetti, Violetta; Couto, Isabel; Viveiros, Miguel; Sabatini, Stefano
Discovery of the 2-phenyl-4,5,6,7-Tetrahydro-1H-indole as a novel anti-hepatitis C virus targeting scaffold
2015 Andreev, Ivan A; Manvar, Dinesh; Barreca, MARIA LETIZIA; Belov, Dmitry S; Basu, Amartya; Sweeney, Noreena L; Ratmanova, Nina K; Lukyanenko, Evgeny R; Manfroni, Giuseppe; Cecchetti, Violetta; Frick, David N; Altieri, Andrea; Kaushik Basu, Neerja; Kurkin, Alexander V.
The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors
2015 Sabatini, Stefano; Manfroni, Giuseppe; Barreca, MARIA LETIZIA; Bauer, Silke M; Gargaro, Marco; Cannalire, Rolando; Astolfi, Andrea; Brea, Jose; Vacca, Carmine; Pirro, Matteo; Massari, Serena; Tabarrini, Oriana; Loza, Maria Isabel; Fallarino, Francesca; Laufer, Stefan A; Cecchetti, Violetta
Tumour cell population growth inhibition and cell death induction of functionalized 6-aminoquinolone derivatives
2015 Franci, G; Manfroni, Giuseppe; Cannalire, Rolando; Felicetti, Tommaso; Tabarrini, Oriana; Salvato, A; Barreca, MARIA LETIZIA; Altucci, L; Cecchetti, Violetta
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors
2016 Corona, Angela; Desantis, Jenny; Massari, Serena; Distinto, Simona; Masaoka, Takashi; Sabatini, Stefano; Esposito, Francesca; Manfroni, Giuseppe; Maccioni, Elias; Cecchetti, Violetta; Pannecouque, Christophe; Le Grice, Stuart F. J.; Tramontano, Enzo; Tabarrini, Oriana
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor
2016 Tarantino, Delia; Cannalire, Rolando; Mastrangelo, Eloise; Croci, Romina; Querat, Gilles; Barreca, MARIA LETIZIA; Bolognesi, Martino; Manfroni, Giuseppe; Cecchetti, Violetta; Milani, Mario
Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents
2016 Kaushik Basu, Neerja; Ratmanova, Nina K.; Manvar, Dinesh; Belov, Dmitry S.; Cevik, Ozge; Basu, Amartya; Yerukhimovich, Mark M.; Lukyanenko, Evgeny R.; Andreev, Ivan A.; Belov, Grigory M.; Manfroni, Giuseppe; Cecchetti, Violetta; Frick, David N.; Kurkin, Alexander V.; Altieri, Andrea; Barreca, MARIA LETIZIA
A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates
2016 Cannalire, Rolando; Barreca, MARIA LETIZIA; Manfroni, Giuseppe; Cecchetti, Violetta
Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium
2017 Cannalire, Rolando; Machado, Diana; Felicetti, Tommaso; Santos Costa, Sofia; Massari, Serena; Manfroni, Giuseppe; Barreca, Maria Letizia; Tabarrini, Oriana; Couto, Isabel; Viveiros, Miguel; Sabatini, Stefano; Cecchetti, Violetta
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors
2017 Astolfi, Andrea; Felicetti, Tommaso; Iraci, Nunzio; Manfroni, Giuseppe; Massari, Serena; Pietrella, Donatella; Tabarrini, Oriana; Kaatz, Glenn W.; Barreca, MARIA LETIZIA; Sabatini, Stefano; Cecchetti, Violetta
Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues
2017 Felicetti, Tommaso; Cannalire, Rolando; Burali, MARIA SOLE; Massari, Serena; Manfroni, Giuseppe; Barreca, MARIA LETIZIA; Tabarrini, Oriana; Schindler, Bryan D; Sabatini, Stefano; Kaatz, Glenn W; Cecchetti, Violetta
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity
2017 Desantis, Jenny; Nannetti, Giulio; Massari, Serena; Letizia Barreca, Maria; Manfroni, Giuseppe; Cecchetti, Violetta; Palù, Giorgio; Goracci, Laura; Loregian, Arianna; Tabarrini, Oriana
Investigation on the effect of known potent S. aureus NorA efflux pump inhibitors on the staphylococcal biofilm formation
2017 Sabatini, Stefano; Piccioni, Miranda; Felicetti, Tommaso; DE MARCO, Stefania; Manfroni, Giuseppe; Pagiotti, Rita; Nocchetti, Morena; Cecchetti, Violetta; Pietrella, Donatella
Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli
2017 Machado, Diana; Fernandes, Laura; Costa, Sofia S.; Cannalire, Rolando; Manfroni, Giuseppe; Tabarrini, Oriana; Couto, Isabel; Sabatini, Stefano; Viveiros, Miguel
Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase
2018 Cannalire, Rolando; Tarantino, Delia; Astolfi, Andrea; Barreca, MARIA LETIZIA; Sabatini, Stefano; Massari, Serena; Tabarrini, Oriana; Milani, Mario; Querat, Gilles; Mastrangelo, Eloise; Manfroni, Giuseppe; Cecchetti, Violetta
Advantageous Use of Ionic Liquids for the Synthesis of Pharmaceutically Relevant Quinolones
2018 Cannalire, Rolando; Tiecco, Matteo; Cecchetti, Violetta; Germani, Raimondo; Manfroni, Giuseppe
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Enantioresolution, stereochemical characterization and biological activity of a chiral large-conductance calcium-activated potassium channel opener. | 2014 | Sardella, Roccaldo; Carotti, Andrea; Manfroni, Giuseppe; Tedesco, D; Martelli, A; Bertucci, C; Cecchetti, Violetta; Natalini, Benedetto | |
| Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization | 2015 | Astolfi, Andrea; Barreca, MARIA LETIZIA; Iraci, Nunzio; Cannalire, Rolando; Sabatini, Stefano; Manfroni, Giuseppe; Cecchetti, Violetta | |
| A Broad Anti-influenza Hybrid Small Molecule that Potently Disrupts the Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits Interaction | 2015 | Massari, Serena; Nannetti, Giulio; Desantis, Jenny; Muratore, Giulia; Sabatini, Stefano; Manfroni, Giuseppe; Mercorelli, Beatrice; Cecchetti, Violetta; Palù, Giorgio; Cruciani, Gabriele; Loregian, Arianna; Goracci, Laura; Tabarrini, Oriana | |
| A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors | 2015 | Astolfi, Andrea; Iraci, Nunzio; Manfroni, Giuseppe; Barreca, MARIA LETIZIA; Cecchetti, Violetta | |
| Boosting Effect of 2-Phenylquinoline Efflux Inhibitors in Combination with Macrolides against Mycobacterium smegmatis and Mycobacterium avium | 2015 | Machado, Diana; Cannalire, Rolando; Santos Costa, Sofia; Manfroni, Giuseppe; Tabarrini, Oriana; Cecchetti, Violetta; Couto, Isabel; Viveiros, Miguel; Sabatini, Stefano | |
| Discovery of the 2-phenyl-4,5,6,7-Tetrahydro-1H-indole as a novel anti-hepatitis C virus targeting scaffold | 2015 | Andreev, Ivan A; Manvar, Dinesh; Barreca, MARIA LETIZIA; Belov, Dmitry S; Basu, Amartya; Sweeney, Noreena L; Ratmanova, Nina K; Lukyanenko, Evgeny R; Manfroni, Giuseppe; Cecchetti, Violetta; Frick, David N; Altieri, Andrea; Kaushik Basu, Neerja; Kurkin, Alexander V. | |
| The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors | 2015 | Sabatini, Stefano; Manfroni, Giuseppe; Barreca, MARIA LETIZIA; Bauer, Silke M; Gargaro, Marco; Cannalire, Rolando; Astolfi, Andrea; Brea, Jose; Vacca, Carmine; Pirro, Matteo; Massari, Serena; Tabarrini, Oriana; Loza, Maria Isabel; Fallarino, Francesca; Laufer, Stefan A; Cecchetti, Violetta | |
| Tumour cell population growth inhibition and cell death induction of functionalized 6-aminoquinolone derivatives | 2015 | Franci, G; Manfroni, Giuseppe; Cannalire, Rolando; Felicetti, Tommaso; Tabarrini, Oriana; Salvato, A; Barreca, MARIA LETIZIA; Altucci, L; Cecchetti, Violetta | |
| Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors | 2016 | Corona, Angela; Desantis, Jenny; Massari, Serena; Distinto, Simona; Masaoka, Takashi; Sabatini, Stefano; Esposito, Francesca; Manfroni, Giuseppe; Maccioni, Elias; Cecchetti, Violetta; Pannecouque, Christophe; Le Grice, Stuart F. J.; Tramontano, Enzo; Tabarrini, Oriana | |
| Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor | 2016 | Tarantino, Delia; Cannalire, Rolando; Mastrangelo, Eloise; Croci, Romina; Querat, Gilles; Barreca, MARIA LETIZIA; Bolognesi, Martino; Manfroni, Giuseppe; Cecchetti, Violetta; Milani, Mario | |
| Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents | 2016 | Kaushik Basu, Neerja; Ratmanova, Nina K.; Manvar, Dinesh; Belov, Dmitry S.; Cevik, Ozge; Basu, Amartya; Yerukhimovich, Mark M.; Lukyanenko, Evgeny R.; Andreev, Ivan A.; Belov, Grigory M.; Manfroni, Giuseppe; Cecchetti, Violetta; Frick, David N.; Kurkin, Alexander V.; Altieri, Andrea; Barreca, MARIA LETIZIA | |
| A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates | 2016 | Cannalire, Rolando; Barreca, MARIA LETIZIA; Manfroni, Giuseppe; Cecchetti, Violetta | |
| Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium | 2017 | Cannalire, Rolando; Machado, Diana; Felicetti, Tommaso; Santos Costa, Sofia; Massari, Serena; Manfroni, Giuseppe; Barreca, Maria Letizia; Tabarrini, Oriana; Couto, Isabel; Viveiros, Miguel; Sabatini, Stefano; Cecchetti, Violetta | |
| Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors | 2017 | Astolfi, Andrea; Felicetti, Tommaso; Iraci, Nunzio; Manfroni, Giuseppe; Massari, Serena; Pietrella, Donatella; Tabarrini, Oriana; Kaatz, Glenn W.; Barreca, MARIA LETIZIA; Sabatini, Stefano; Cecchetti, Violetta | |
| Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues | 2017 | Felicetti, Tommaso; Cannalire, Rolando; Burali, MARIA SOLE; Massari, Serena; Manfroni, Giuseppe; Barreca, MARIA LETIZIA; Tabarrini, Oriana; Schindler, Bryan D; Sabatini, Stefano; Kaatz, Glenn W; Cecchetti, Violetta | |
| Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity | 2017 | Desantis, Jenny; Nannetti, Giulio; Massari, Serena; Letizia Barreca, Maria; Manfroni, Giuseppe; Cecchetti, Violetta; Palù, Giorgio; Goracci, Laura; Loregian, Arianna; Tabarrini, Oriana | |
| Investigation on the effect of known potent S. aureus NorA efflux pump inhibitors on the staphylococcal biofilm formation | 2017 | Sabatini, Stefano; Piccioni, Miranda; Felicetti, Tommaso; DE MARCO, Stefania; Manfroni, Giuseppe; Pagiotti, Rita; Nocchetti, Morena; Cecchetti, Violetta; Pietrella, Donatella | |
| Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli | 2017 | Machado, Diana; Fernandes, Laura; Costa, Sofia S.; Cannalire, Rolando; Manfroni, Giuseppe; Tabarrini, Oriana; Couto, Isabel; Sabatini, Stefano; Viveiros, Miguel | |
| Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase | 2018 | Cannalire, Rolando; Tarantino, Delia; Astolfi, Andrea; Barreca, MARIA LETIZIA; Sabatini, Stefano; Massari, Serena; Tabarrini, Oriana; Milani, Mario; Querat, Gilles; Mastrangelo, Eloise; Manfroni, Giuseppe; Cecchetti, Violetta | |
| Advantageous Use of Ionic Liquids for the Synthesis of Pharmaceutically Relevant Quinolones | 2018 | Cannalire, Rolando; Tiecco, Matteo; Cecchetti, Violetta; Germani, Raimondo; Manfroni, Giuseppe |
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