IRIS - Res&Arch Institutional Research Information System - Research & Archive

CRUCIANI, Gabriele
 Distribuzione geografica
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Continente #
NA - Nord America 6.102
EU - Europa 5.488
AS - Asia 1.047
AF - Africa 17
Continente sconosciuto - Info sul continente non disponibili 12
SA - Sud America 10
OC - Oceania 2
Totale 12.678
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Nazione #
US - Stati Uniti d'America 6.088
UA - Ucraina 1.185
IE - Irlanda 1.159
SE - Svezia 1.000
IT - Italia 838
HK - Hong Kong 414
VN - Vietnam 336
DE - Germania 281
FI - Finlandia 276
RU - Federazione Russa 241
CN - Cina 159
FR - Francia 158
GB - Regno Unito 141
TR - Turchia 53
CH - Svizzera 34
BE - Belgio 32
AT - Austria 28
JP - Giappone 28
PL - Polonia 27
GR - Grecia 24
UZ - Uzbekistan 21
NL - Olanda 19
MA - Marocco 14
EU - Europa 12
CA - Canada 11
RO - Romania 10
ES - Italia 9
CZ - Repubblica Ceca 8
LB - Libano 8
SG - Singapore 6
CL - Cile 4
SK - Slovacchia (Repubblica Slovacca) 4
GE - Georgia 3
IL - Israele 3
KR - Corea 3
MD - Moldavia 3
MY - Malesia 3
PE - Perù 3
PK - Pakistan 3
AU - Australia 2
BD - Bangladesh 2
BG - Bulgaria 2
CI - Costa d'Avorio 2
CO - Colombia 2
EE - Estonia 2
IN - India 2
MX - Messico 2
AE - Emirati Arabi Uniti 1
BR - Brasile 1
GH - Ghana 1
HR - Croazia 1
HU - Ungheria 1
ID - Indonesia 1
IQ - Iraq 1
LI - Liechtenstein 1
LU - Lussemburgo 1
NO - Norvegia 1
PA - Panama 1
PT - Portogallo 1
RS - Serbia 1
Totale 12.678
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Città #
Chandler 1.473
Dublin 1.158
Jacksonville 607
San Mateo 530
Hong Kong 412
Dong Ket 331
Perugia 286
Medford 277
Princeton 276
Altamura 250
Lawrence 207
Wilmington 196
Ann Arbor 187
Des Moines 186
Andover 157
Fremont 127
Beijing 118
Ashburn 94
Saint Petersburg 84
Boardman 80
Izmir 49
Helsinki 47
San Paolo di Civitate 42
Philadelphia 40
Norwalk 39
Woodbridge 35
Redmond 31
Brussels 30
Falls Church 30
Tokyo 25
Moscow 22
Houston 19
Shanghai 19
New York 16
San Diego 16
Rome 15
Ouezzane 14
Auburn Hills 13
Mcallen 12
Milan 12
Den Haag 11
Chicago 10
Chieti 10
Bologna 9
Lausanne 9
Redwood City 9
Tappahannock 9
Madrid 8
Paris 8
London 7
Frankfurt Am Main 6
Parma 6
Seattle 6
Simi Valley 6
Dearborn 5
Florence 5
Genova 5
Ottawa 5
Salerno 5
Terni 5
Bratislava 4
Hanoi 4
Iesi 4
Kraków 4
Lappeenranta 4
Modena 4
Montréal 4
Stockholm 4
Timisoara 4
Trieste 4
Alameda 3
Amsterdam 3
Aurisina 3
Bordeaux 3
Chisinau 3
Fairfield 3
Frankfurt am Main 3
Horia 3
Kiev 3
Latina 3
Lima 3
Nanning 3
Padova 3
Spoleto 3
St Louis 3
Abidjan 2
Anguillara Sabazia 2
Augusta 2
Bari 2
Bellinzago Lombardo 2
Brisbane 2
Cardiff 2
Cartagena 2
Cesana Brianza 2
Dallas 2
Dhaka 2
Dorsten 2
Esslingen am Neckar 2
Frattamaggiore 2
Giulianova 2
Totale 7.821
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Nome #
1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story So Far And Perspectives (Part 2): Action in Other Targets and Antitargets 187
1,4-Dihydropyridine scaffold in medicinal chemistry, the story so far and perspectives (part 1): action in ion channels and GPCRs 172
A 3D-QSAR Study on the Srtuctural Requirements for Binding to CB1 and CB2 Cannabinoid Receptors 100
Studi sul Meccanismo di Stereospecificità della Lipasi Candida Rugosa nella Idrolisi di Esteri di Piridil-1-etanoli 95
Application of chemometrics to the screening of hazardous chemicals. A case study 93
Discovery of Novel and Cardioselective Diltiazem-like Calcium Channel Blockers via Virtual Screening 88
BioGPS: Navigating biological space to predict polypharmacology, off-targeting, and selectivity 86
3D-QSAR GRID Descriptors and Chemometric Tools in the development of Selective Antagonists of Muscarinic Receptor 83
Syntehesis and Structural Studies of Cationic Bis- and Tris(pyrazol-1-yl)methane Acyl and Methul Complexex of Ruthenium(II); Localizazion of the counterion in Solution by NOESY NMR Spectroscopy. 82
6-Aminoquinolones: a New Class of Quinolone Antibacterials? 82
3D-QSAR methods on the basis of ligand-receptor complexes. Application of COMBINE and GRID/GOLPE methodologies to a series of CYP1A2 ligands 80
Fluorinated analogues of Bosentan: effects on the antagonist activity and the metabolic stability 80
La chemiometria nell'ottimizzazione dei prodotti alimentari 79
Principal Properties of aromatic substituents. A multivariate approach for design in QSAR 79
GBR Compounds and Mepyramines as Cocaine Abuse Therapeutics: Chemometric Studies on Selectivity Using Grid Independent Descriptors (GRIND) 77
3D QSAR of Mutagenic Heterocyclic Amines that are Substrates of Cytochrome P458 1A2 77
A quantitative fluorimetric analysis of a multicomponent system based on a modified PCA-SM method 77
Inhibitor of Ovarian Cancer Cells Growth by Virtual Screening: A New Thiazole Derivative Targeting Human Thymidylate Synthase 77
Structural Differences of Matrix Metalloproteinases with Potential Implications for Inhibitor Selectivity Examined by the GRID/CPCA Approach 75
Molecular fields in quantitative structure-permeation relationships: the VolSurf approach 74
Experimental design and multivariate calibration in the development, set-up and validation of a differential pulse polarographic and UV spectrophotometric method for the simultaneous plasmatic determination of the therapeutic ... 73
Lipostar, a comprehensive platform-neutral cheminformatics tool for lipidomics 73
Natural and Synthetic Xanthones as Monoamine Oxidase Inhibitors: Biological Assay and 3D‐QSAR 72
Autocorrelation as a tool for a congruent description of molecu¬les in 3D-QSAR studies 72
Analytical strategies to assess the functional metabolome of vitamin E 72
Calcium channel antagonists discovered by a multidisciplinary approach 71
Comparative Binding Energy (COMBINE) Analysis on a Series of Glycogen Phosphorylase Inhibitors. Comparison with GRID/GOLPE Models 70
PCDD and PCDF from the combustion of MSW in a pilot plant 70
MetaSite: Understanding Metabolism in Human Cytochromes from the Perspective of the Chemist 70
Structure-Metabolism Relations, and the Challenge of Predicting Biotransformation 69
Synthesis, In Vitro Skin Permeation Studies, and PLS-Analysis of New Naproxen Derivatives 69
VolSurf: a new tool for the pharmacokinetic optimization of lead compounds 69
Suitability of molecular descriptors for database mining. A comparative analysis. 69
Molecular lipophilicity descriptors: a multivariate analysis 69
6-Substituted Benzopyrans as Potassium Channel Activators: Synthesis, Vasodilator Properties, and Multivariate Analysis 69
A chemometric approach for evaluating the efficiency of a pilot plant for MSW combustion 69
Vitamin E: metabolism and molecular aspects 69
Structural Requirements for Binding to Cannabinoid Receptors 68
Theoretical versus empirical molecular descriptors in monosubsti¬tuted benzenes. A chemometric study 68
Tautomer Enumeration and Stability Prediction for Virtual Screening on Large Chemical Databases 67
The antibacterial activity of quinolones against E.coli: a chemometric study 67
Smart Region Definition: A New Way To Improve the Predictive Ability and Interpretability of Three-Dimensional Quantitative Structure-Activity Relationships 66
Application of the PLS method to develop quantitative predictive models in toxicology and ecotoxicology 66
Quantitative structure–property relationship modeling of ruthenium sensitizers for solar cells applications: novel tools for designing promising candidates 66
Chemometric approach to a QSAR study of peptides behaving as NK-2 receptor antagonists 65
Diagnostic application of lipidomics fingerprints to bladder carcinoma 65
Stereoselective Behavior of the Functional Diltiazem Analogue 1-[(4-Chlorophenyl)sulfonyl]-2-(2-thienyl)pyrrolidine, a New L-Type Calcium Channel Blocker 64
Some application of the partial least squares method 64
Absolute configuration and biological profile of two thiazinooxadiazol-3-ones with L-type calcium channel activity: a study of the structural effects 64
A Strategy for the Incorporation of Water Molecules Present in a Ligand Binding Site into a Three-Dimensional Quantitative Structure-Activity Relathionship 63
QSAR study and VolSurf characterization of anti-HIV quinolone library 63
Use of a Combined GLUE/ALMOND Approach in QSAR-Studies on (aryl) Bridged 2-Aminobenzonitriles Inhibiting HIV-1 Reverse Transcriptase 63
Hydrogen Bonding Interactions of Covalently-Bonded Fluorine Atoms: From Crystallographic Data to a New Angular Function in the GRID Force Field 63
Molecular Field-Derived Descriptors for the Multivariate Modeling of Pharmacochinetic Data 61
GRIND-derived pharmacophore model for a series of alpha-tropanyl derivative ligands of the sigma-2 receptor 61
Conformer- and Alignment-Independent Model for Predicting Structurally Diverse Competitive CYP2C9 Inhibitors 61
Transporter-Mediated Efflux Influences CNS Side Effects: ABCB1, from Antitarget to Target 61
Chemometric Methodologies in a Quantitative Structure-Activity Relationship Study: the Antibacterial Activity of 6-Aminoquinolones 61
Impiego dell'analisi multivariata per lo studio di relazioni quantitative tra serie di dati sperimentali. 61
Structure-metabolism relationships in human-AOX: Chemical insights from a large database of aza-aromatic and amide compounds 61
Synthesis and Antibacterial Evaluation of [1,3]Benzothiazino[3,2-a]quinoline and [3,1]Benzothiazino[1,2-a]quinoline-6-carboxylic Acid Derivatives 60
A search for specificity in DNA-drug interactions 60
A comparative chemometric study of QSAR descriptors 59
Optimization of Small-Molecule Inhibitors of Influenza Virus Polymerase: From Thiophene-3-Carboxamide to Polyamido Scaffolds 59
Arachidonic acid to docosahexaenoic acid ratio (AA/DHA): a strong clinical outcome predictor in DHA-based nutritional therapy of pediatric NASH 59
Prediction ability of regression models. Part 2. Selection of the best predictive PLS model 58
Surface Descriptors for Protein Ligand Affinity Prediction 57
Antileishmanial Chalcones: Statistical Design, Synthesis, andThree-Dimensional Quantitative Structure-Activity Relationship Analysis 57
BDDCS Class Prediction for New Molecular Entities 57
GRIND/ALMOND investigations on CysLT(1) receptor antagonists of the quinolinyl(bridged)aryl type 56
D-optimal designs in QSAR 56
Recent improvement in the GRID Force Field. 1. The docking Procedure GLUE 56
Overview of the biological activities of a methanol extract from wild red belt conk, fomitopsis Pinicola (Agaricomycetes), fruiting bodies from central Italy 56
Grid Independent Descriptors (GRIND) in the Rational Drug Design of Muscarinic Antagonists 55
Interaction of DDSDEEN peptide with N-CAM protein. Possible mechanism enhancing neuronal differentiation 55
Comparison of chemometric methods for QSAR 55
A new set of Principal Properties for Heteroaromatics obtained by GRIDQuant. Struct.-Act. Relat., 15, 108-120 (1996). 55
Improved Potency of Indole-Based NorA Efflux Pump Inhibitors: From Serendipity toward Rational Design and Development 55
Integrating Crystallography into Early Metabolism Studies 54
A Broad Anti-influenza Hybrid Small Molecule that Potently Disrupts the Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits Interaction 54
Effects of different routes of application on ethylenediurea persistence in tobacco leaves 54
ADME-Space: A new tool for medicinal chemists to explore ADME properties 54
SARS-CoV2 infection impairs the metabolism and redox function of cellular glutathione 54
Molecular interaction fields 53
Chemometric approach in a QSAR study: the antibacterial and antimicotic activities of benzofused heteroaromatic derivatives 53
Conformational equilibria in trans-diarylethylenes: spectral and photophysical properties of rotamers of (2-naphtyl)-2(6'-quinolyl)ethylene, derived from kinetic and statistical fluore¬scence analysis 53
Variable selection in PLS analysis 52
Generating Optimal Linear PLS Estimations (GOLPE): An Advanced Chemometric Tool for Handling 3D-QSAR Problems 52
Improving the prediction of the brain disposition for orally administered drugs using BDDCS 52
An innovative application of the "flexible" GRID/PCA computational method: Study of differences in selectivity between PGAs from Escherichia coli and a Providentia rettgeri mutant 51
Discovery of Novel Inhibitors of the NorA Multidrug Transporter of Staphylococcus aureus. 51
Response surfaces for modelling biological activities by principal properties of substituents: the CARSO procedure. 51
Structural properties of water-organic solvent mixtures: a corre¬lation with physico-chemical properties of the solvent 51
Groupings of organic substituents 51
Structure-based Rationalization of Antitumor Drug Mechanism of Action by a MIF Approach 50
Homodimeric enzymes as drug targets 50
In silico pKa Prediction and ADME Profiling 50
A Novel Strategy for Improving Ligand Selectivity in Receptor-Based Drug Design 50
Ligand Promiscuity between the Efflux Pumps Human P-Glycoprotein and S. aureus NorA 50
Novel Low-Concentration Amphiphilic Inhibitors and their Application to Flow Assurance 50
Totale 6.672
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Categoria #
all - tutte 46.213
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.213
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201997 0 0 0 0 0 0 0 0 0 16 76 5
2019/20201.205 33 23 185 16 180 31 186 52 201 158 22 118
2020/20212.708 13 182 131 177 692 271 153 15 329 124 219 402
2021/20222.307 58 400 54 186 94 33 23 698 68 38 262 393
2022/20234.592 315 788 85 386 390 576 32 239 1.531 32 157 61
2023/20241.001 119 178 88 32 36 15 247 22 249 15 0 0
Totale 13.235