GNAS1 gene is located at the long arm of chromosome 20 (q13.32). GNAS1 gene deletion has never been investigated in MDS. A GNAS1 activating mutation (R201) was recently found in MDS. We applied FISH and DHPLC plus sequencing to investigate GNAS1 gene in MDS cases with and without del(20q) at karyotype.
The GNAS1 gene in myelodysplastic syndromes (MDS).
DI GIACOMO, DANIKA;Lema Fernandez AG;PIERINI, TIZIANA;CRESCENZI, Barbara;BRANDIMARTE, LUCIA;MATTEUCCI, Caterina;MECUCCI, Cristina
2014
Abstract
GNAS1 gene is located at the long arm of chromosome 20 (q13.32). GNAS1 gene deletion has never been investigated in MDS. A GNAS1 activating mutation (R201) was recently found in MDS. We applied FISH and DHPLC plus sequencing to investigate GNAS1 gene in MDS cases with and without del(20q) at karyotype.File in questo prodotto:
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