Chronic kidney disease (CKD), dyslipidemias and cardiovascular risk are related conditions. CKD is associated with an increased risk of total and cardiovascular mortality. Atherosclerosis can lead to chronic renal failure and at the same time CKD is considered an independent cardiovascular risk factor. The main types of dyslipidemia secondary to nephropathies are dyslipidemia of nephrotic syndrome and dyslipidemia of advanced CKD. Patients with CKD are considered in the highest CV risk category; thus, lipid profile should be evaluated since the first stages of CKD. This review focuses on the current knowledge on the relationship between CKD and cardiovascular diseases, on the pathogenesis of the dyslipidemias secondary to nephropathies and on the main therapeutic options used to treat these dyslipidemias
Dyslipidemias and chronic kidney disease: a focus on pathogenesis and treatment
DE VUONO, STEFANO;RICCI, MARIA ANASTASIA;MANNARINO, MASSIMO RAFFAELE;LUPATTELLI, Graziana
2014
Abstract
Chronic kidney disease (CKD), dyslipidemias and cardiovascular risk are related conditions. CKD is associated with an increased risk of total and cardiovascular mortality. Atherosclerosis can lead to chronic renal failure and at the same time CKD is considered an independent cardiovascular risk factor. The main types of dyslipidemia secondary to nephropathies are dyslipidemia of nephrotic syndrome and dyslipidemia of advanced CKD. Patients with CKD are considered in the highest CV risk category; thus, lipid profile should be evaluated since the first stages of CKD. This review focuses on the current knowledge on the relationship between CKD and cardiovascular diseases, on the pathogenesis of the dyslipidemias secondary to nephropathies and on the main therapeutic options used to treat these dyslipidemiasI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
