As the upregulation of opioid receptors after articular damage has been well demonstrated both in human and veterinary medicine, the use of opiates injected in the joint, rather than systemically, might guarantee a greater comfort of the animal, a better mobility of the affected joint in the immediate post-operative period with lower side effects. The analgesic efficacy of intra- articular (IA) 50 mg tramadol is documented in human surgery as providing long lasting analgesia and lower side effects than 50 mg IV1. Similarly, 2 mg/kg IA in horses after arthroscopy determined lower pain scores than saline2. We aim to compare the analgesic efficacy of IA tramadol administered at two different doses in horses after arthroscopy
Effects on pain control of two different doses of intra-articular tramadol in horses after arthroscopic surgery
NANNARONE, Sara;PEPE, Marco;MENCHETTI, LAURA;VUERICH, MATTEO;BECCATI, FRANCESCA;GIALLETTI, Rodolfo;CHIARADIA, Elisabetta
2017
Abstract
As the upregulation of opioid receptors after articular damage has been well demonstrated both in human and veterinary medicine, the use of opiates injected in the joint, rather than systemically, might guarantee a greater comfort of the animal, a better mobility of the affected joint in the immediate post-operative period with lower side effects. The analgesic efficacy of intra- articular (IA) 50 mg tramadol is documented in human surgery as providing long lasting analgesia and lower side effects than 50 mg IV1. Similarly, 2 mg/kg IA in horses after arthroscopy determined lower pain scores than saline2. We aim to compare the analgesic efficacy of IA tramadol administered at two different doses in horses after arthroscopyI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
