An unprecedented Michael/intramolecular etherification cascade reaction of phenyl vinyl selenone with 3-hydroxyoxindoles under aqueous basic conditions at room temperature is described. The method provides a domino access to new spirooxindole 2,2- disubstituted oxetanes in moderate to good yields under mild reaction conditions.
Synthesis of spirooxindole oxetanes through a domino reaction of 3‐hydroxyoxindoles and phenyl vinyl selenone
Martina Palomba;Luca Sancineto;Luana Bagnoli;Claudio Santi;Francesca Marini
2019
Abstract
An unprecedented Michael/intramolecular etherification cascade reaction of phenyl vinyl selenone with 3-hydroxyoxindoles under aqueous basic conditions at room temperature is described. The method provides a domino access to new spirooxindole 2,2- disubstituted oxetanes in moderate to good yields under mild reaction conditions.File in questo prodotto:
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