IRIS - Res&Arch Institutional Research Information System - Research & Archive

ORLACCHIO, Antonio
 Distribuzione geografica
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Continente #
NA - Nord America 6.418
AS - Asia 5.527
EU - Europa 4.499
SA - Sud America 1.293
AF - Africa 156
Continente sconosciuto - Info sul continente non disponibili 37
OC - Oceania 10
Totale 17.940
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Nazione #
US - Stati Uniti d'America 6.227
SG - Singapore 2.417
IE - Irlanda 1.121
RU - Federazione Russa 1.078
BR - Brasile 1.041
VN - Vietnam 893
HK - Hong Kong 709
CN - Cina 673
IT - Italia 550
FR - Francia 402
FI - Finlandia 337
DE - Germania 211
SE - Svezia 136
GB - Regno Unito 133
IN - India 126
UA - Ucraina 124
AT - Austria 109
BD - Bangladesh 97
CA - Canada 89
AR - Argentina 86
PL - Polonia 85
ID - Indonesia 77
KR - Corea 63
MX - Messico 59
IQ - Iraq 58
JP - Giappone 57
ZA - Sudafrica 55
TR - Turchia 49
NL - Olanda 46
UZ - Uzbekistan 41
EC - Ecuador 40
PK - Pakistan 37
EU - Europa 36
MY - Malesia 36
CO - Colombia 33
RO - Romania 32
SA - Arabia Saudita 30
TH - Thailandia 29
CH - Svizzera 28
PH - Filippine 28
VE - Venezuela 28
MA - Marocco 26
ES - Italia 23
CL - Cile 20
BE - Belgio 16
JO - Giordania 15
LB - Libano 15
GR - Grecia 14
KE - Kenya 14
PE - Perù 14
PY - Paraguay 14
EG - Egitto 13
CZ - Repubblica Ceca 12
AZ - Azerbaigian 11
AU - Australia 10
LT - Lituania 9
NP - Nepal 9
OM - Oman 9
TN - Tunisia 9
JM - Giamaica 8
KZ - Kazakistan 8
PA - Panama 8
UY - Uruguay 8
AE - Emirati Arabi Uniti 7
BO - Bolivia 7
DZ - Algeria 7
DK - Danimarca 6
ET - Etiopia 6
IL - Israele 6
KW - Kuwait 6
NI - Nicaragua 6
SN - Senegal 6
AL - Albania 5
KG - Kirghizistan 5
SK - Slovacchia (Repubblica Slovacca) 5
TT - Trinidad e Tobago 5
CI - Costa d'Avorio 4
CR - Costa Rica 4
GH - Ghana 4
HN - Honduras 4
SY - Repubblica araba siriana 4
DO - Repubblica Dominicana 3
MD - Moldavia 3
PT - Portogallo 3
QA - Qatar 3
BG - Bulgaria 2
BY - Bielorussia 2
GA - Gabon 2
LV - Lettonia 2
MU - Mauritius 2
PS - Palestinian Territory 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AM - Armenia 1
AO - Angola 1
BF - Burkina Faso 1
BH - Bahrain 1
BN - Brunei Darussalam 1
BW - Botswana 1
CU - Cuba 1
GD - Grenada 1
Totale 17.921
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Città #
Singapore 1.564
Dublin 1.113
San Jose 812
Hong Kong 702
San Mateo 675
Dong Ket 520
Chandler 503
Ashburn 448
Moscow 385
Santa Clara 344
Boardman 308
Medford 291
Princeton 291
Lauterbourg 270
Altamura 193
Wilmington 180
Redmond 169
Lawrence 155
Ho Chi Minh City 144
Beijing 131
Perugia 118
Los Angeles 111
Ann Arbor 96
New York 94
Saint Petersburg 91
São Paulo 83
Munich 81
Hanoi 76
The Dalles 72
Vienna 67
Seoul 57
Helsinki 56
Norwalk 51
Tokyo 46
Jakarta 44
Nuremberg 35
Warsaw 35
Andover 34
Montreal 34
Brooklyn 33
Rio de Janeiro 33
San Paolo di Civitate 32
Orem 31
Boston 28
Johannesburg 28
Stockholm 28
Timisoara 28
Bangkok 27
Chennai 27
Kraków 27
Rome 27
Chicago 26
Houston 26
Baghdad 25
Amsterdam 23
Dallas 23
Denver 23
Shanghai 23
Belo Horizonte 22
Frankfurt am Main 22
Guangzhou 22
Atlanta 20
Haiphong 20
Phoenix 20
Kuala Selangor 19
Turku 19
Jacksonville 18
Milan 18
Mumbai 18
Piscataway 18
Den Haag 17
London 17
Tashkent 17
Brussels 16
Amman 15
Campinas 15
Curitiba 15
Manila 15
Poplar 15
Quito 15
Dhaka 14
Lahore 14
Manchester 14
Mexico City 14
Ottawa 14
Porto Alegre 14
Redwood City 14
Brasília 13
Charlotte 13
Council Bluffs 13
Salvador 13
Cape Town 12
Falkenstein 12
Tianjin 12
Baku 11
Changsha 11
Goiânia 11
Guarulhos 11
Istanbul 11
Nairobi 11
Totale 11.642
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Nome #
Beneficial effect of Crocus sativus stigma extract in amyloid-beta degradation by monocytes from sporadic Alzheimer's disease patients 161
Alpha2-macroglobulin polymorphisms in Italian sporadic and familial Alzheimer's disease 156
COX inhibitors and bone: A safer impact on osteoblasts by NO-releasing NSAIDs 131
ALS5/SPG11/KIAA1840 mutations cause autosomal recessive axonal Charcot-Marie-Tooth disease 129
Clinical and genetic study of an Italian family with complicated hereditary spastic paraplegia and Alzheimer's disease 129
Beta-hexosaminidase, alpha-D-mannosidase, and beta-mannosidase expression in serum from patients with carbohydrate-deficient glycoprotein syndrome type I 123
1H-MRS in patients with multiple sclerosis undergoing treatment with interferon beta-1a: results of a preliminary study 123
Trans-crocetin improves amyloid-β degradation in monocytes from Alzheimer's Disease patients 123
CSF biomarkers, impairment of cerebral hemodynamics and degree of cognitive decline: An overview in different dementia subtypes 122
Lesser motor disability in adulthood: A ten-year follow-up of a dyskinetic patient with ADCY5 mutation 119
Caspase 3 activation and PARP cleavage in lymphocytes from newborn babies of diabetic mothers with unbalanced glycaemic control 118
Effects of vitamin C on fibroblasts from sporadic Alzheimer's disease patients 114
Activity levels of a beta1,6 N-acetylglucosaminyltransferase in lymphomonocytes from multiple sclerosis patients 114
Clinico-genetic study of two Japanese pedigrees with hereditary spastic paraparesis and Alzheimer’s disease 114
miR128 up-regulation correlates with impaired amyloid β(1-42) degradation in monocytes from patients with sporadic Alzheimer's disease 113
Acid glycohydrolase activities in lymphomonocyte plasma- membranes of patients with multiple sclerosis 112
Spastic paraplegia type 4: A novel SPAST splice site donor mutation and expansion of the phenotype variability 112
HSP-SPG5A/CYP7B1: unusual clinical and genetic characteristics in an Indian family 106
A novel AIFM1 missense mutation in a Japanese patient with ataxic sensory neuronopathy and hearing impairment 102
Cathepsin D expression is decreased in Alzheimer's disease fibroblasts 101
Phenotype variability and allelic heterogeneity in KMT2B-Associated disease 101
SPG11-related parkinsonism: Clinical profile, molecular imaging and l-dopa response 101
Nano- from nature to nurture: A comprehensive review on facets, trends, perspectives and sustainability of nanotechnology in the food sector 101
Prevalence of Cardiovascular Diseases in South Asians: Scrutinizing Traditional Risk Factors and Newly Recognized Risk Factors Sarcopenia and Osteopenia/Osteoporosis 100
A clinico-genetical study in a large cohort of patients with spastic paraplegia type 4 (SPG4) 100
a-D-Mannosidases in patients with familial Alzheimer’s disease 100
Recurrent de novo missense variant E210K in UBTF causes juvenile dystonia-parkinsonism 100
Transmission Jeopardy of Adenomatosis Polyposis Coli and Methylenetetrahydrofolate Reductase in Colorectal Cancer 100
Lysosomal proteases cathepsin D, B, and L are down-regulated in fibroblasts from Alzheimer’s disease patients 99
Crocus sativus L. stigma extract improves amyloid-β degradation mediated by Cathepsin B in monocytes from Alzheimer’s Disease patients 99
New pathological findings in an international cohort of hereditary spastic paraplegia 4 patients. 97
Hereditary spastic paraplegia and Alzheimer’s disease: clinical and genetic study of a Brazilian family 97
Clinical and genetic research in a large Ukrainian family with autosomal recessive hereditary spastic paraplegia 95
Association analysis between Alzheimer's disease and the Nicastrin gene polymorphisms 95
Clinical and genetic features of a large cohort of Italian SPG4 patients from the D.A.I.S.Y. collaborative network 95
ALS phenotypes with mutations in SPG11 93
Spastic paraplegia type 4: a novel SPAST splice site donor mutation and expansion of the phenotype variability 93
Identification of ALS5/SPG11/KIAA1840 Mutations in Patients with Autosomal Recessive Form of Charcot-Marie-Tooth Disease Type 2 92
Haploinsufficiency of KMT2B causes myoclonus-dystonia with impaired psychomotor ability 92
Absence of association between Alzheimer disease and the -491 regulatory region polymorphism of APOE 91
The Puzzle of Hereditary Spastic Paraplegia: From Epidemiology to Treatment 90
A new SPG4/SPAST mutation in an Italian family with hereditary spastic paraplegia and Alzheimer's disease 89
Hereditary Spastic Paraplegia: An Update 89
Expression of cathepsins S and D signals a distinctive biochemical trait in CD34(+) hematopoietic stem cells of relapsing-remitting multiple sclerosis patients 88
A homozygous loss-of-function mutation in DNAJA3 causes hereditary motor and sensory neuropathy with spastic paraplegia (HMSN type V) 88
A new CSF1R mutation presenting with an extensive white matter lesion mimicking primary progressive multiple sclerosis 88
Ras differentially regulates lysosomal enzymes expression 87
Cathepsin D expression and regulation in fibroblasts from Alzheimer’s disease patients 86
Differential regulation of lysosomal enzymes in fibroblasts from Alzheimer’s disease patients 86
Cytokine secretion and nitric oxide production by mononuclear cells of patients with multiple sclerosis 86
Spastic paraplegia type 4: a novel SPAST splice site donor mutation and expansion of the phenotype variability 86
Hereditary spastic paraplegia type 4 (SPG4): an international multicenter clinical and genetic study. 85
Alpha-D-mannosidase properties in serum of patients with amyotrophic lateral sclerosis 85
Cathepsin D expression and processing in fibroblasts from Alzheimer’s disease patients 85
Acanthocytosis as a predisposing factor for non-ketotic hyperglycaemia induced chorea-ballism 85
Clinical and genetic study of a Japanese family with complicated hereditary spastic paraplegia and Alzheimer's disease 85
Constitutive expression of beta-N-acetylhexosaminidase in a microglial cell line: transcriptional modulation by lipopolysaccharide and serum factors 84
A homozygous loss-of-function mutation in DNAJA3 causes hereditary motor and sensory neuropathy with spastic paraplegia (HMSN type V) 84
Clinical and molecular profile of a Japanese cohort of patients with dyskinesia 84
Active secretion of lysosomal glycohydrolases by activated human platelets “in vivo” studies on lysosomal release and molecular mechanisms regulating their secretion 83
A novel compound heterozygous TH mutation in a Japanese case of dopa-responsive dystonia with mild clinical course 83
Neuronal inclusion formation and axonal degeneration in mutant TFG transgenic mice 83
Association study of the 5-HT6 receptor gene in Alzheimer’s disease 82
Elevated beta-N-acetylhexosaminidase activity in focal dystonia fibroblasts 82
a-D-Mannosidases in fibroblasts from patients with Alzheimer’s disease 81
AD with subcortical white matter lesions and vascular dementia: CSF markers for differential diagnosis 81
Lack of association between Alzheimer's disease and the promoter region polymorphisms of the nicastrin gene 80
An α-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease 80
A novel mutation in the SPG3A gene (atlastin) in hereditary spastic paraplegia 79
Alpha-D-mannosidase properties in serum of patients with amyotrophic lateral sclerosis 79
Epidemiological, clinical, and genetic study in a large cohort of patients with spastic paraplegia 79
Up-regulation of glycohydrolases in Alzheimer's Disease fibroblasts correlates with Ras activation 79
Hereditary Spastic Paraplegia Type 4 (SPG4): A Clinico-Genetic Study in a Large Cohort of Patients with Spastic Paraplegia 78
Spastic paraplegia type 31: A novel REEP1 splice site donor variant and expansion of the phenotype variability 78
Spastic paraplegia type 4: A novel SPAST splice site donor mutation and expansion of the phenotype variability 78
Characterization of human Enah gene 78
A new SPG4 mutation in a variant form of spastic paraplegia with congenital arachnoid cysts 78
A homozygous mutation of VWA3B causes cerebellar ataxia with intellectual disability 77
Regulation of lysosomal enzymes expression in fibroblasts from Alzheimer’s disease patients 77
SPG11 mutations cause autosomal recessive axonal Charcot-Marie-Tooth disease 77
Search for new genes causing dementia: targets for novel diagnostics and therapeutics 77
Silver syndrome variant of hereditary spastic paraplegia: A locus to 4p and allelism with SPG4 76
Clinical-Genetic Features Influencing Disability in Spastic Paraplegia Type 4: A Cross-sectional Study by the Italian DAISY Network 76
Apolipoprotein E 3/2 genotype is associated with early onset cognitive dysfunction in SLE 75
Association study of the 5-hydroxytryptamine(6) receptor gene in Alzheimer's disease 74
A clinico-genetic study in a large cohort of patients with hereditary spastic paraplegia type 4 (SPG4) 74
Impairment of lysosomal system in neurodegenerative diseases 74
Restoration of arylsulphatase A activity in murine metachromatic leukodistrophy oligodendrocytes by retroviral vector-mediated gene transfer 74
Choreoathetosis, dystonia, and myoclonus in 3 siblings with autosomal recessive spinocerebellar ataxia type 16 73
Expression and processing of cathepsin D in fibroblasts of patients with Alzheimer’s disease 73
Cathepsin D, B and L are down-regulated in fibroblasts from Alzheimer’s disease patients 73
Cohort profile of the Japan Dystonia Consortium: Genetic diagnosis and characteristics of movement disorders in Japan 73
Autosomal recessive hereditary spastic paraplegia with thin corpus callosum: A novel mutation in the SPG11 gene and further evidence for genetic heterogeneity 72
Absence of association between APOA1 polymorphism and Alzheimer’s disease 72
Hereditary spastic paraplegia and Alzheimer's disease: hypothesis of a founder effect of a SPG4/SPAST mutation 72
Cloning of human MENA gene 72
miR128 up-regulation correlates with impaired Amyloid-β42 degradation in monocytes of patients with sporadic Alzheimer’s disease 72
Cathepsin B and L are down-regulated in fibroblasts from Alzheimer’s disease patients 71
Influence of Ras up-regulation on lysosomal enzymes expression 71
Therapy with drug product AZD-103 may ease Alzheimer's disease 71
Totale 9.140
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Categoria #
all - tutte 98.991
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 98.991
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021526 0 0 0 0 0 0 0 0 0 0 0 526
2021/20222.168 19 406 171 20 167 18 59 662 25 53 267 301
2022/20232.592 300 489 34 70 158 128 1 89 1.238 9 54 22
2023/2024993 45 88 49 23 3 12 251 27 21 52 219 203
2024/20253.651 21 329 73 61 338 273 165 205 940 251 715 280
2025/20267.068 506 371 435 1.150 883 640 1.098 354 865 512 208 46
Totale 19.525