ORLACCHIO, Antonio
 Distribuzione geografica
Continente #
NA - Nord America 8.379
AS - Asia 5.584
EU - Europa 4.673
Continente sconosciuto - Info sul continente non disponibili 1.632
SA - Sud America 1.333
AF - Africa 162
OC - Oceania 11
Totale 21.774
Nazione #
US - Stati Uniti d'America 7.972
SG - Singapore 2.425
IE - Irlanda 1.122
RU - Federazione Russa 1.080
BR - Brasile 1.065
VN - Vietnam 893
HK - Hong Kong 715
IT - Italia 696
CN - Cina 683
FR - Francia 402
FI - Finlandia 337
DE - Germania 213
CA - Canada 182
GB - Regno Unito 150
IN - India 139
SE - Svezia 136
UA - Ucraina 124
AT - Austria 109
BD - Bangladesh 100
AR - Argentina 88
PL - Polonia 85
ID - Indonesia 77
KR - Corea 63
MX - Messico 61
JP - Giappone 59
IQ - Iraq 58
ZA - Sudafrica 57
TR - Turchia 52
NL - Olanda 47
EC - Ecuador 43
UZ - Uzbekistan 41
PK - Pakistan 38
CO - Colombia 37
MY - Malesia 37
EU - Europa 36
VE - Venezuela 33
RO - Romania 32
SA - Arabia Saudita 31
TH - Thailandia 30
CH - Svizzera 28
PH - Filippine 28
MA - Marocco 26
ES - Italia 25
CL - Cile 21
CR - Costa Rica 21
HN - Honduras 20
NI - Nicaragua 19
PR - Porto Rico 17
BE - Belgio 16
JM - Giamaica 16
TT - Trinidad e Tobago 16
JO - Giordania 15
LB - Libano 15
PE - Perù 15
SV - El Salvador 15
GR - Grecia 14
GT - Guatemala 14
KE - Kenya 14
PY - Paraguay 14
EG - Egitto 13
IL - Israele 13
CZ - Repubblica Ceca 12
AZ - Azerbaigian 11
AU - Australia 10
OM - Oman 10
GP - Guadalupe 9
LT - Lituania 9
NP - Nepal 9
TN - Tunisia 9
KZ - Kazakistan 8
PA - Panama 8
UY - Uruguay 8
AE - Emirati Arabi Uniti 7
BO - Bolivia 7
CW - ???statistics.table.value.countryCode.CW??? 7
DZ - Algeria 7
DK - Danimarca 6
ET - Etiopia 6
KW - Kuwait 6
SN - Senegal 6
AL - Albania 5
KG - Kirghizistan 5
SK - Slovacchia (Repubblica Slovacca) 5
CI - Costa d'Avorio 4
GH - Ghana 4
SY - Repubblica araba siriana 4
DO - Repubblica Dominicana 3
MD - Moldavia 3
PT - Portogallo 3
QA - Qatar 3
SC - Seychelles 3
BF - Burkina Faso 2
BG - Bulgaria 2
BY - Bielorussia 2
EE - Estonia 2
GA - Gabon 2
GD - Grenada 2
HR - Croazia 2
LC - Santa Lucia 2
LV - Lettonia 2
Totale 20.158
Città #
Singapore 1.569
Dublin 1.113
San Jose 976
Ashburn 855
Hong Kong 705
San Mateo 675
Dong Ket 520
Chandler 503
Santa Clara 392
Moscow 385
Council Bluffs 374
Boardman 309
Princeton 294
Medford 291
Lauterbourg 270
Altamura 193
Wilmington 180
Redmond 169
Lawrence 155
Ho Chi Minh City 144
Beijing 138
Los Angeles 130
Perugia 118
New York 106
São Paulo 100
Ann Arbor 96
Saint Petersburg 91
Munich 81
Hanoi 76
The Dalles 72
Vienna 67
Dallas 60
Seoul 57
Helsinki 56
Montreal 51
Norwalk 51
Tokyo 48
Jakarta 44
Rome 44
Chennai 38
Brooklyn 36
Nuremberg 35
Warsaw 35
Andover 34
Atlanta 34
Chicago 34
Rio de Janeiro 34
Orem 33
Phoenix 33
San Paolo di Civitate 32
Milan 30
Toronto 30
Bangkok 28
Boston 28
Houston 28
Johannesburg 28
Stockholm 28
Timisoara 28
Denver 27
Kraków 27
Baghdad 25
Shanghai 25
Amsterdam 23
Belo Horizonte 22
Frankfurt am Main 22
Guangzhou 22
North Bergen 22
Piscataway 22
Jacksonville 21
Haiphong 20
San José 20
Kuala Selangor 19
London 19
Mumbai 19
Turku 19
Managua 18
Den Haag 17
Tashkent 17
Brussels 16
Charlotte 16
Amman 15
Campinas 15
Curitiba 15
Manila 15
Mexico City 15
Ottawa 15
Poplar 15
Quito 15
Dhaka 14
Lahore 14
Manchester 14
Porto Alegre 14
Redwood City 14
San Francisco 14
Brasília 13
Cape Town 13
Salvador 13
Falkenstein 12
Guarulhos 12
Guayaquil 12
Totale 12.901
Nome #
Beneficial effect of Crocus sativus stigma extract in amyloid-beta degradation by monocytes from sporadic Alzheimer's disease patients 173
Alpha2-macroglobulin polymorphisms in Italian sporadic and familial Alzheimer's disease 164
COX inhibitors and bone: A safer impact on osteoblasts by NO-releasing NSAIDs 141
ALS5/SPG11/KIAA1840 mutations cause autosomal recessive axonal Charcot-Marie-Tooth disease 139
Clinical and genetic study of an Italian family with complicated hereditary spastic paraplegia and Alzheimer's disease 135
1H-MRS in patients with multiple sclerosis undergoing treatment with interferon beta-1a: results of a preliminary study 134
Beta-hexosaminidase, alpha-D-mannosidase, and beta-mannosidase expression in serum from patients with carbohydrate-deficient glycoprotein syndrome type I 133
Trans-crocetin improves amyloid-β degradation in monocytes from Alzheimer's Disease patients 133
CSF biomarkers, impairment of cerebral hemodynamics and degree of cognitive decline: An overview in different dementia subtypes 128
miR128 up-regulation correlates with impaired amyloid β(1-42) degradation in monocytes from patients with sporadic Alzheimer's disease 127
Caspase 3 activation and PARP cleavage in lymphocytes from newborn babies of diabetic mothers with unbalanced glycaemic control 126
Lesser motor disability in adulthood: A ten-year follow-up of a dyskinetic patient with ADCY5 mutation 124
Activity levels of a beta1,6 N-acetylglucosaminyltransferase in lymphomonocytes from multiple sclerosis patients 123
Effects of vitamin C on fibroblasts from sporadic Alzheimer's disease patients 121
Acid glycohydrolase activities in lymphomonocyte plasma- membranes of patients with multiple sclerosis 120
Spastic paraplegia type 4: A novel SPAST splice site donor mutation and expansion of the phenotype variability 120
Clinico-genetic study of two Japanese pedigrees with hereditary spastic paraparesis and Alzheimer’s disease 116
Phenotype variability and allelic heterogeneity in KMT2B-Associated disease 112
SPG11-related parkinsonism: Clinical profile, molecular imaging and l-dopa response 112
HSP-SPG5A/CYP7B1: unusual clinical and genetic characteristics in an Indian family 112
Ras differentially regulates lysosomal enzymes expression 111
Nano- from nature to nurture: A comprehensive review on facets, trends, perspectives and sustainability of nanotechnology in the food sector 111
Recurrent de novo missense variant E210K in UBTF causes juvenile dystonia-parkinsonism 110
a-D-Mannosidases in patients with familial Alzheimer’s disease 108
A novel AIFM1 missense mutation in a Japanese patient with ataxic sensory neuronopathy and hearing impairment 108
Prevalence of Cardiovascular Diseases in South Asians: Scrutinizing Traditional Risk Factors and Newly Recognized Risk Factors Sarcopenia and Osteopenia/Osteoporosis 107
New pathological findings in an international cohort of hereditary spastic paraplegia 4 patients. 107
Cathepsin D expression is decreased in Alzheimer's disease fibroblasts 107
A clinico-genetical study in a large cohort of patients with spastic paraplegia type 4 (SPG4) 106
Active secretion of lysosomal glycohydrolases by activated human platelets “in vivo” studies on lysosomal release and molecular mechanisms regulating their secretion 106
Transmission Jeopardy of Adenomatosis Polyposis Coli and Methylenetetrahydrofolate Reductase in Colorectal Cancer 105
Clinical and genetic features of a large cohort of Italian SPG4 patients from the D.A.I.S.Y. collaborative network 105
Epidemiological, clinical, and genetic study in a large cohort of patients with spastic paraplegia 104
Crocus sativus L. stigma extract improves amyloid-β degradation mediated by Cathepsin B in monocytes from Alzheimer’s Disease patients 104
Clinical and genetic research in a large Ukrainian family with autosomal recessive hereditary spastic paraplegia 103
The Puzzle of Hereditary Spastic Paraplegia: From Epidemiology to Treatment 103
Lysosomal proteases cathepsin D, B, and L are down-regulated in fibroblasts from Alzheimer’s disease patients 103
Hereditary spastic paraplegia and Alzheimer’s disease: clinical and genetic study of a Brazilian family 103
Hereditary Spastic Paraplegia: An Update 101
Association analysis between Alzheimer's disease and the Nicastrin gene polymorphisms 100
Identification of ALS5/SPG11/KIAA1840 Mutations in Patients with Autosomal Recessive Form of Charcot-Marie-Tooth Disease Type 2 99
Spastic paraplegia type 4: a novel SPAST splice site donor mutation and expansion of the phenotype variability 99
Absence of association between Alzheimer disease and the -491 regulatory region polymorphism of APOE 99
Acanthocytosis as a predisposing factor for non-ketotic hyperglycaemia induced chorea-ballism 98
ALS phenotypes with mutations in SPG11 97
Expression of cathepsins S and D signals a distinctive biochemical trait in CD34(+) hematopoietic stem cells of relapsing-remitting multiple sclerosis patients 95
A homozygous loss-of-function mutation in DNAJA3 causes hereditary motor and sensory neuropathy with spastic paraplegia (HMSN type V) 95
Haploinsufficiency of KMT2B causes myoclonus-dystonia with impaired psychomotor ability 95
Clinical and molecular profile of a Japanese cohort of patients with dyskinesia 95
Constitutive expression of beta-N-acetylhexosaminidase in a microglial cell line: transcriptional modulation by lipopolysaccharide and serum factors 94
A new CSF1R mutation presenting with an extensive white matter lesion mimicking primary progressive multiple sclerosis 94
Neuronal inclusion formation and axonal degeneration in mutant TFG transgenic mice 94
Cathepsin D expression and processing in fibroblasts from Alzheimer’s disease patients 93
A new SPG4/SPAST mutation in an Italian family with hereditary spastic paraplegia and Alzheimer's disease 93
Elevated beta-N-acetylhexosaminidase activity in focal dystonia fibroblasts 93
Hereditary spastic paraplegia type 4 (SPG4): an international multicenter clinical and genetic study. 92
Alpha-D-mannosidase properties in serum of patients with amyotrophic lateral sclerosis 92
Differential regulation of lysosomal enzymes in fibroblasts from Alzheimer’s disease patients 92
Cytokine secretion and nitric oxide production by mononuclear cells of patients with multiple sclerosis 92
A homozygous loss-of-function mutation in DNAJA3 causes HMSN type V 91
Cathepsin D expression and regulation in fibroblasts from Alzheimer’s disease patients 91
Spastic paraplegia type 4: a novel SPAST splice site donor mutation and expansion of the phenotype variability 91
Spastic paraplegia type 4: A novel SPAST splice site donor mutation and expansion of the phenotype variability 91
Molecular epidemiology of dystonia in Japan 91
Hereditary spastic paraplegia: Genetic heterogeneity and common pathways 90
A homozygous loss-of-function mutation in DNAJA3 causes hereditary motor and sensory neuropathy with spastic paraplegia (HMSN type V) 90
AD with subcortical white matter lesions and vascular dementia: CSF markers for differential diagnosis 89
Characterization of human Enah gene 89
A novel mutation in the SPG3A gene (atlastin) in hereditary spastic paraplegia 88
A novel compound heterozygous TH mutation in a Japanese case of dopa-responsive dystonia with mild clinical course 88
Up-regulation of glycohydrolases in Alzheimer's Disease fibroblasts correlates with Ras activation 87
Clinical and genetic study of a Japanese family with complicated hereditary spastic paraplegia and Alzheimer's disease 87
A new SPG4 mutation in a variant form of spastic paraplegia with congenital arachnoid cysts 87
A homozygous mutation of VWA3B causes cerebellar ataxia with intellectual disability 86
Restoration of arylsulphatase A activity in murine metachromatic leukodistrophy oligodendrocytes by retroviral vector-mediated gene transfer 86
Development of a New Tool for 3D Modeling for Regenerative Medicine 85
Association study of the 5-HT6 receptor gene in Alzheimer’s disease 85
An α-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease 85
Spastic paraplegia type 31: A novel REEP1 splice site donor variant and expansion of the phenotype variability 85
Silver syndrome variant of hereditary spastic paraplegia: A locus to 4p and allelism with SPG4 84
a-D-Mannosidases in fibroblasts from patients with Alzheimer’s disease 84
Alpha-D-mannosidase properties in serum of patients with amyotrophic lateral sclerosis 84
Lack of association between Alzheimer's disease and the promoter region polymorphisms of the nicastrin gene 84
Clinical-Genetic Features Influencing Disability in Spastic Paraplegia Type 4: A Cross-sectional Study by the Italian DAISY Network 84
Genetics of Alzheimer’s disease 83
Hereditary Spastic Paraplegia Type 4 (SPG4): A Clinico-Genetic Study in a Large Cohort of Patients with Spastic Paraplegia 83
Autosomal recessive hereditary spastic paraplegia with thin corpus callosum: A novel mutation in the SPG11 gene and further evidence for genetic heterogeneity 83
Regulation of lysosomal enzymes expression in fibroblasts from Alzheimer’s disease patients 83
VWA3B mutated in a family with cerebellar ataxia with psychomotor retardation 83
SPG11 mutations cause autosomal recessive axonal Charcot-Marie-Tooth disease 81
Impairment of lysosomal system in neurodegenerative diseases 81
Search for new genes causing dementia: targets for novel diagnostics and therapeutics 81
Absence of association between APOA1 polymorphism and Alzheimer’s disease 80
Apolipoprotein E 3/2 genotype is associated with early onset cognitive dysfunction in SLE 80
Association study of the 5-hydroxytryptamine(6) receptor gene in Alzheimer's disease 79
Influence of Ras up-regulation on lysosomal enzymes expression 79
A clinico-genetic study in a large cohort of patients with hereditary spastic paraplegia type 4 (SPG4) 78
Expression and processing of cathepsin D in fibroblasts of patients with Alzheimer’s disease 78
Clinical and genetic study of a large SPG4 Italian family with hereditary spastic paraplegia and early-onset familial Alzheimer’s disease 78
Cathepsin D, B and L are down-regulated in fibroblasts from Alzheimer’s disease patients 78
Totale 9.976
Categoria #
all - tutte 112.625
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 112.625


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.572 0 0 0 20 167 18 59 662 25 53 267 301
2022/20232.592 300 489 34 70 158 128 1 89 1.238 9 54 22
2023/2024993 45 88 49 23 3 12 251 27 21 52 219 203
2024/20253.651 21 329 73 61 338 273 165 205 940 251 715 280
2025/20267.085 506 371 435 1.150 883 640 1.098 354 865 512 208 63
2026/20272.232 79 137 346 1.670 0 0 0 0 0 0 0 0
Totale 21.774