IRIS - Res&Arch Institutional Research Information System - Research & Archive

BARRECA, MARIA LETIZIA
 Distribuzione geografica
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Continente #
NA - Nord America 5.110
EU - Europa 3.788
AS - Asia 3.474
SA - Sud America 592
AF - Africa 64
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 3
Totale 13.039
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Nazione #
US - Stati Uniti d'America 5.021
SG - Singapore 1.361
IT - Italia 746
UA - Ucraina 733
IE - Irlanda 595
CN - Cina 552
VN - Vietnam 549
HK - Hong Kong 533
BR - Brasile 520
RU - Federazione Russa 474
SE - Svezia 327
DE - Germania 258
KR - Corea 199
FI - Finlandia 192
GB - Regno Unito 138
BE - Belgio 82
TR - Turchia 66
IN - India 50
CA - Canada 41
FR - Francia 38
AT - Austria 34
PL - Polonia 33
MX - Messico 32
AR - Argentina 28
NL - Olanda 28
CH - Svizzera 25
JP - Giappone 24
BD - Bangladesh 23
ZA - Sudafrica 23
UZ - Uzbekistan 21
ES - Italia 18
CZ - Repubblica Ceca 16
EC - Ecuador 16
RO - Romania 16
ID - Indonesia 15
IQ - Iraq 11
PK - Pakistan 10
AE - Emirati Arabi Uniti 9
CI - Costa d'Avorio 9
SA - Arabia Saudita 9
BG - Bulgaria 8
MA - Marocco 8
CL - Cile 6
EU - Europa 6
TN - Tunisia 6
AL - Albania 5
IR - Iran 5
PE - Perù 5
VE - Venezuela 5
CO - Colombia 4
GR - Grecia 4
KE - Kenya 4
LB - Libano 4
NP - Nepal 4
PA - Panama 4
UY - Uruguay 4
AM - Armenia 3
CM - Camerun 3
IL - Israele 3
PS - Palestinian Territory 3
PY - Paraguay 3
SK - Slovacchia (Repubblica Slovacca) 3
AZ - Azerbaigian 2
DK - Danimarca 2
DZ - Algeria 2
EG - Egitto 2
GD - Grenada 2
HN - Honduras 2
HU - Ungheria 2
JM - Giamaica 2
JO - Giordania 2
KZ - Kazakistan 2
LT - Lituania 2
MD - Moldavia 2
MN - Mongolia 2
OM - Oman 2
PH - Filippine 2
RS - Serbia 2
TW - Taiwan 2
XK - ???statistics.table.value.countryCode.XK??? 2
AU - Australia 1
BA - Bosnia-Erzegovina 1
BO - Bolivia 1
BW - Botswana 1
BZ - Belize 1
CR - Costa Rica 1
CY - Cipro 1
DO - Repubblica Dominicana 1
EE - Estonia 1
ET - Etiopia 1
GE - Georgia 1
HR - Croazia 1
KH - Cambogia 1
LK - Sri Lanka 1
LV - Lettonia 1
ML - Mali 1
MR - Mauritania 1
NA - Namibia 1
NZ - Nuova Zelanda 1
PR - Porto Rico 1
Totale 13.031
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Città #
Singapore 940
Chandler 789
Dublin 593
Hong Kong 521
Perugia 405
Jacksonville 388
Dong Ket 357
San Mateo 326
Ashburn 262
Boardman 254
Santa Clara 206
Seoul 197
Medford 159
Princeton 158
Wilmington 132
Moscow 121
Beijing 120
Fremont 119
Altamura 118
Dearborn 108
Ann Arbor 100
Andover 94
Los Angeles 94
Lawrence 89
Piscataway 88
Brussels 82
Ho Chi Minh City 82
São Paulo 65
The Dalles 60
New York 59
Saint Petersburg 49
Izmir 48
Des Moines 45
Munich 44
Hanoi 38
West Jordan 38
Redmond 36
Hefei 30
Norwalk 29
Dallas 27
Warsaw 27
Helsinki 26
Rome 26
Redwood City 23
San Giustino 23
Tokyo 22
Houston 21
Spoleto 21
Atlanta 20
Brooklyn 20
Nanjing 19
Turku 19
Lappeenranta 18
Shanghai 18
Montreal 17
Columbus 16
Johannesburg 16
Rio de Janeiro 16
Stockholm 15
Denver 14
Kunming 14
Orem 14
San Francisco 14
Chennai 13
Chicago 13
Falls Church 13
Auburn Hills 12
Changsha 12
Curitiba 12
Guangzhou 12
London 12
Belo Horizonte 11
Brasília 11
Manchester 11
Philadelphia 11
Phoenix 11
Poplar 11
San Jose 11
San Paolo di Civitate 11
Vienna 11
Ankara 10
Seattle 10
Simi Valley 10
Toronto 10
Abidjan 9
Boston 9
Olomouc 9
Querétaro 9
Recife 9
Amsterdam 8
Den Haag 8
Hải Dương 8
Jinan 8
Nanchang 8
Woodbridge 8
Zhengzhou 8
Bologna 7
Bucharest 7
Council Bluffs 7
Haiphong 7
Totale 8.276
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Nome #
1,3-DIIDRO-BENZIMIDAZOLONI ANALOGHI: PROGETTAZIONE, SINTESI E SAR DI NUOVI INIBITORI NON-NUCLEOSIDICI DELL’RT 302
1,4-Benzothiazine ATP-Sensitive Potassium Channel Openers: Modifications at the C-2 and C-6 Positions 302
1,3-Diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 295
1,2,4-Triazolo[1,5-a]pyrimidines: Efficient One-step Synthesis and Functionalization as Influenza Polymerase PA-PB1 Interaction Disruptors 173
Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase 139
Prion protein ligands as therapeutic agents for neurodegenerative disorders 133
3D pharmacophore models for 1,2,3,4-tetrahydroisoquinoline derivatives acting as anticonvulsant agents 129
Alternate NF-κB-independent signaling reactivation of latent HIV-1 provirus 127
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors 123
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists 116
New Insights on KCa3.1 Channel Modulation 114
A 1,8-Naphthyridone Derivative Targets the HIV-1 Tat-Mediated Transcription and Potently Inhibits the HIV-1 Replication. 113
New anti-ovarian cancer quinolone derivatives acting by modulating microRNA processing machinery 112
2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction 111
Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development 110
A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors 109
Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase 108
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 107
C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors 106
Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation 106
A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates 101
A Comprehensive Structural Overview of p38 Mitogen-Activated Protein Kinase in Complex with ATP-Site and Non-ATP-Site Binders 100
Targeting CDKs to inhibit the HIV-1 TAT-mediated transcription 99
Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents 99
Computer-Aided Identification of Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 98
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors 98
From Serendipity to Rational Identification of the 5,6,7,8-Tetrahydrobenzo [4,5]thieno[2,3-d]pyrimidin-4(3H)-one Core as a New Chemotype of AKT1 Inhibitors for Acute Myeloid Leukemia 97
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B Palm Site I inhibitors case study. 96
Binding Mode Prediction of Strand Transfer HIV-1 Integrase Inhibitors Using Tn5 Transposase as a Plausible Surrogate Model for HIV-1 Integrase 95
Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions 95
Deciphering the molecular recognition mechanism of multidrug resistance staphylococcus aureus nora efflux pump using a supervised molecular dynamics approach 95
Pharmacological inactivation of the prion protein by targeting a folding intermediate 95
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 92
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 92
Design e Sintesi di composti a struttura 3-Indol-Gliossilamidica come potenziali inibitori dell’integrasi dell’HIV-1. 91
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 91
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model. 91
HIV-1 Integrase strand transfer inhibitors (INSTIs): design, synthesis and biological evaluation 90
p38 alpha MAPK and Type I Inhibitors: Binding Site Analysis and Use of Target Ensembles in Virtual Screening 90
New Pyrazolobenzothiazine Derivatives As Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors 90
Design and synthesis of NR2B Subtype-Selective Antagonist 89
Binding models of reversible inhibitors to type-B monoamine oxidase 89
Homology Modeling of AMPA Receptors: Route to the identification of noncompetitive antagonists binding site 88
Co-crystal structure determination and cellular evaluation of 1,4-dihydropyrazolo[4,3-c] [1,2] benzothiazine 5,5-dioxide p38α MAPK inhibitors 88
Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors 88
Structure-Based Pharmacophore Identification of New Chemical Scaffolds as Non–Nucleoside reverse Transcriptase Inhibitors 87
Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position 87
Pharmacophore Identification of New Chemical Scaffolds as Non-Nucleoside Reverse Transcriptase Inhibitors. 86
Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface 86
From Quinoline to Quinazoline-Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search 86
HIV-1 Integrase Inhibitors as anti-AIDS agents: Structure-Activity Relationships (SAR) of new Diketo Acids and Analogs. 85
Binding modes of noncompetitive AMPA Antagonists: A computational approach 85
Computational Strategies for Discovering novel HIV-1 RT Inhibitors 85
5-Arylidene-2-imino-4-thiazolidinones: Design and synthesis of novel anti-inflammatory agents 85
Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 84
A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity 84
Sustainable, three-component, one-pot procedure to obtain active anti-flavivirus agents 84
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 83
The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors 83
Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization 82
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 81
6-Aminoquinolones targeting HCV NS5B polymerase. 81
DECODING THE FUNCTION OF THE N-TERMINAL TAIL OF THE CELLULAR PRION PROTEIN TO INSPIRE NOVEL THERAPEUTIC AVENUES FOR NEURODEGENERATIVE DISEASES 81
Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues 81
A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation 80
PAPAIN-CATALYZED HYDROLYSIS OF ARYL ESTERS - A COMPARISON OF THE HANSCH, DOCKING AND COMFA METHODS 80
AMPA Receptor Antagonists as Potential Anticonvulsant Drugs 80
Structural optimization of the 2-Phenyl-4-hydroxyquinoline Class of S. aureus NorA Efflux Pump Inhibitors 80
New C-6 functionalized quinoline NorA inhibitors strongly synergize with ciprofloxacin against planktonic and biofilm growing resistant Staphylococcus aureus strains 78
Molecular Modeling, synthesis and SAR of anti-HIV agents. 77
Discovery of novel HIV-1 Integrase Inhibitors: a multidisciplinary approach 76
HIV-1 Integrase Inhibitors: Pharmacophore Modeling and Rational Drug Design 76
Sintesi e SAR di inibitori dell’integrasi dell’HIV-1 a struttura 1-benzyl-1H-indolica. 75
Rational design, synthesis and SAR of HIV-1 integrase Inhibitors 75
Fighting Antimicrobial Resistance: Insights on How the Staphylococcus aureus NorA Efflux Pump Recognizes 2-Phenylquinoline Inhibitors by Supervised Molecular Dynamics (SuMD) and Molecular Docking Simulations 75
Molecular Dynamics Studies of the Wild-Type and Double Mutant HIV-1 Integrase Complexed with the 5CITEP Inhibitor: Mechanism for Inhibition and Drug Resistance 74
Antagonisti noncompetitivi del recettore AMPA: progettazione, sintesi, SAR e studio del profilo farmacocinetico. 74
Identification of Anti-Influenza A Compounds Inhibiting the Viral Non-Structural Protein 1 (NS1) Using a Type I Interferon-Driven Screening Strategy 73
Drug Design, Innoative Strategie Sintetiche e Valutazione Biologica di Nuovi Inibitori dell’Integrasi dell’HIV-1. 73
Exploration of the binding mode of HIV-1 integrase strand transfer inhibitors through different computational approaches. 73
Cinnamoyl compounds as small-molecules inhibitors of histone acetyltransferase enzymes 73
Tetrahydroisoquinoline derivatives: a new class of non-competitive ampa receptor antagonists with potential anticonvulsant activity 72
Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains 72
Equisetum arvense standardized dried extract hinders age-related osteosarcopenia. 71
Synthesis, resolution, stereochemistry, and molecular modeling of (R)- and (S)-2-acetyl-1-(40-chlorophenyl)-6,7-dimethoxy-1,2,3,4- tetrahydroisoquinoline AMPAR antagonists 71
Switching the three-component Biginelli-like reaction conditions for the regioselective synthesis of new 2-amino[1,2,4]triazolo[1,5-a]pyrimidines 70
Discovery of a Novel and Highly Potent Noncompetitive AMPA Receptor Antagonist 70
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity 70
Novel targets for HIV therapy: small molecules blocking IN-LEDGF/p75 interaction 69
Identificazione di Nuovi Inibitori Non-Nucleosidici della Trascrittasi Inversa dell’ HIV-1 Mediante Tecniche di Virtual screening. 69
Small Molecules Targeting DNA Polymerase Theta (POLθ) as Promising Synthetic Lethal Agents for Precision Cancer Therapy 68
STRUCTURAL MODIFICATION OF DIKETO ACID PORTION IN 1H-BENZYLINDOLE DERIVATIVES HIV-1 INTEGRASE INHIBITORS 68
Sviluppo di modello farmacoforico predittivo per gli NR2B antagonisti del recettore NMDA 68
Re-evolution of the 2-phenylquinolines: Ligand-Based Design, Synthesis, and Biological Evaluation of a Potent New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors to Combat Antimicrobial Resistance 68
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor 68
Functionalized sulfonyl anthranilic acid derivatives inhibit replication of all the four dengue serotypes 67
DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF A SERIES OF 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONES AS DUAL INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 INTEGRASE AND THE REVERSE TRANSCRIPTASE RNASE H DOMAIN. 67
Nuovo modello farmacoforico per inibitori dell’Integrasi dell’HIV-1: ottimizzazione della potenza di composti a struttura 1H-benzilindolica 67
NNRTI TBZ-analoghi: progettazione razionale, sintesi e SAR 67
Induced-fit docking approach provides insight into the binding mode and mechanism of action of HIV-1 integrase inhibitors. ChemMedChem 67
Totale 9.469
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Categoria #
all - tutte 60.019
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 60.019
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.007 0 0 0 0 0 154 158 13 172 27 110 373
2021/20221.419 32 248 33 59 95 12 18 409 68 34 176 235
2022/20232.319 196 407 76 195 172 256 3 116 760 11 81 46
2023/20241.070 57 158 36 21 17 22 177 56 177 67 123 159
2024/20252.471 16 251 80 198 241 108 281 154 495 171 303 173
2025/20262.840 375 405 265 799 581 415 0 0 0 0 0 0
Totale 13.544