IRIS - Res&Arch Institutional Research Information System - Research & Archive

BARRECA, MARIA LETIZIA
 Distribuzione geografica
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Continente #
NA - Nord America 6.219
AS - Asia 4.329
EU - Europa 4.327
SA - Sud America 760
Continente sconosciuto - Info sul continente non disponibili 531
AF - Africa 130
OC - Oceania 4
Totale 16.300
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Nazione #
US - Stati Uniti d'America 6.064
SG - Singapore 1.740
IT - Italia 845
UA - Ucraina 736
CN - Cina 652
RU - Federazione Russa 633
VN - Vietnam 612
IE - Irlanda 595
BR - Brasile 589
HK - Hong Kong 578
SE - Svezia 328
DE - Germania 270
FR - Francia 214
FI - Finlandia 209
KR - Corea 199
GB - Regno Unito 163
IN - India 105
TR - Turchia 92
BE - Belgio 82
BD - Bangladesh 80
CA - Canada 68
AR - Argentina 52
MX - Messico 44
NL - Olanda 42
AT - Austria 36
IQ - Iraq 36
PL - Polonia 36
ZA - Sudafrica 33
EC - Ecuador 31
UZ - Uzbekistan 31
PK - Pakistan 29
JP - Giappone 28
CH - Svizzera 26
CO - Colombia 26
SA - Arabia Saudita 26
ID - Indonesia 22
ES - Italia 21
RO - Romania 21
PH - Filippine 20
CZ - Repubblica Ceca 17
MA - Marocco 17
CL - Cile 15
ET - Etiopia 15
AE - Emirati Arabi Uniti 14
TN - Tunisia 12
VE - Venezuela 12
UY - Uruguay 11
AL - Albania 10
BG - Bulgaria 10
CI - Costa d'Avorio 10
PE - Perù 10
PY - Paraguay 10
JO - Giordania 9
EG - Egitto 8
KE - Kenya 8
CR - Costa Rica 7
DZ - Algeria 7
LB - Libano 7
EU - Europa 6
JM - Giamaica 6
PA - Panama 6
GR - Grecia 5
IL - Israele 5
IR - Iran 5
PS - Palestinian Territory 5
AO - Angola 4
KZ - Kazakistan 4
NP - Nepal 4
PR - Porto Rico 4
AM - Armenia 3
AZ - Azerbaigian 3
BO - Bolivia 3
CM - Camerun 3
DO - Repubblica Dominicana 3
HR - Croazia 3
LT - Lituania 3
LV - Lettonia 3
MN - Mongolia 3
MY - Malesia 3
NI - Nicaragua 3
OM - Oman 3
SK - Slovacchia (Repubblica Slovacca) 3
SY - Repubblica araba siriana 3
BA - Bosnia-Erzegovina 2
DK - Danimarca 2
GA - Gabon 2
GD - Grenada 2
HN - Honduras 2
HU - Ungheria 2
MD - Moldavia 2
MU - Mauritius 2
NZ - Nuova Zelanda 2
RS - Serbia 2
SV - El Salvador 2
TH - Thailandia 2
TT - Trinidad e Tobago 2
TW - Taiwan 2
XK - ???statistics.table.value.countryCode.XK??? 2
AU - Australia 1
BJ - Benin 1
Totale 15.751
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Città #
Singapore 1.275
Chandler 789
Dublin 593
Hong Kong 565
San Jose 488
Perugia 436
Jacksonville 391
Ashburn 361
Dong Ket 357
San Mateo 326
Santa Clara 256
Boardman 254
Seoul 197
Moscow 189
Medford 159
Princeton 159
Lauterbourg 151
Beijing 138
Wilmington 133
Los Angeles 127
Fremont 120
Altamura 118
Dearborn 108
The Dalles 108
Ann Arbor 100
Ho Chi Minh City 100
Andover 94
Piscataway 94
Lawrence 89
New York 87
Brussels 82
São Paulo 76
Hanoi 52
Izmir 51
Saint Petersburg 49
Des Moines 48
Munich 44
Helsinki 43
West Jordan 38
Redmond 36
Dallas 35
Rome 32
Hefei 30
Orem 30
Norwalk 29
Council Bluffs 28
Montreal 28
Warsaw 28
Tokyo 25
Atlanta 24
Houston 24
Redwood City 23
San Giustino 23
Brooklyn 22
Buffalo 22
Shanghai 21
Spoleto 21
Johannesburg 20
Nanjing 19
Rio de Janeiro 19
Turku 19
Denver 18
Lappeenranta 18
Phoenix 18
Columbus 16
London 16
Philadelphia 16
San Francisco 16
Chennai 15
Chicago 15
Stockholm 15
Tashkent 15
Toronto 15
Amsterdam 14
Falls Church 14
Kunming 14
Manchester 14
Belo Horizonte 13
Curitiba 13
Jeddah 13
Mexico City 13
Vienna 13
Addis Ababa 12
Auburn Hills 12
Baghdad 12
Brasília 12
Changsha 12
Guangzhou 12
Guayaquil 12
Ankara 11
Milan 11
Poplar 11
San Paolo di Civitate 11
Abidjan 10
Haiphong 10
Recife 10
Seattle 10
Simi Valley 10
Bologna 9
Boston 9
Totale 9.913
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Nome #
1,3-DIIDRO-BENZIMIDAZOLONI ANALOGHI: PROGETTAZIONE, SINTESI E SAR DI NUOVI INIBITORI NON-NUCLEOSIDICI DELL’RT 335
1,3-Diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 322
1,4-Benzothiazine ATP-Sensitive Potassium Channel Openers: Modifications at the C-2 and C-6 Positions 321
1,2,4-Triazolo[1,5-a]pyrimidines: Efficient One-step Synthesis and Functionalization as Influenza Polymerase PA-PB1 Interaction Disruptors 207
Alternate NF-κB-independent signaling reactivation of latent HIV-1 provirus 159
Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase 156
New anti-ovarian cancer quinolone derivatives acting by modulating microRNA processing machinery 155
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors 149
Prion protein ligands as therapeutic agents for neurodegenerative disorders 146
3D pharmacophore models for 1,2,3,4-tetrahydroisoquinoline derivatives acting as anticonvulsant agents 146
New Insights on KCa3.1 Channel Modulation 146
C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors 145
Pharmacological inactivation of the prion protein by targeting a folding intermediate 144
A 1,8-Naphthyridone Derivative Targets the HIV-1 Tat-Mediated Transcription and Potently Inhibits the HIV-1 Replication. 142
2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction 139
A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates 136
From Quinoline to Quinazoline-Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search 136
Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development 135
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists 132
Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase 129
Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation 128
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 127
A Comprehensive Structural Overview of p38 Mitogen-Activated Protein Kinase in Complex with ATP-Site and Non-ATP-Site Binders 126
A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors 124
Targeting CDKs to inhibit the HIV-1 TAT-mediated transcription 117
Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents 117
Computer-Aided Identification of Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 116
Deciphering the molecular recognition mechanism of multidrug resistance staphylococcus aureus nora efflux pump using a supervised molecular dynamics approach 115
From Serendipity to Rational Identification of the 5,6,7,8-Tetrahydrobenzo [4,5]thieno[2,3-d]pyrimidin-4(3H)-one Core as a New Chemotype of AKT1 Inhibitors for Acute Myeloid Leukemia 115
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors 114
Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface 114
Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions 113
Co-crystal structure determination and cellular evaluation of 1,4-dihydropyrazolo[4,3-c] [1,2] benzothiazine 5,5-dioxide p38α MAPK inhibitors 112
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B Palm Site I inhibitors case study. 111
New Pyrazolobenzothiazine Derivatives As Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors 110
A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation 109
New C-6 functionalized quinoline NorA inhibitors strongly synergize with ciprofloxacin against planktonic and biofilm growing resistant Staphylococcus aureus strains 109
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 109
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 109
p38 alpha MAPK and Type I Inhibitors: Binding Site Analysis and Use of Target Ensembles in Virtual Screening 109
Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 108
Binding Mode Prediction of Strand Transfer HIV-1 Integrase Inhibitors Using Tn5 Transposase as a Plausible Surrogate Model for HIV-1 Integrase 107
Binding models of reversible inhibitors to type-B monoamine oxidase 106
Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors 106
Design and synthesis of NR2B Subtype-Selective Antagonist 105
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model. 105
A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity 105
Equisetum arvense standardized dried extract hinders age-related osteosarcopenia. 103
Homology Modeling of AMPA Receptors: Route to the identification of noncompetitive antagonists binding site 103
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 103
Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium 103
Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position 103
The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors 101
Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues 101
HIV-1 Integrase strand transfer inhibitors (INSTIs): design, synthesis and biological evaluation 100
Binding modes of noncompetitive AMPA Antagonists: A computational approach 100
6-Aminoquinolones targeting HCV NS5B polymerase. 99
Design e Sintesi di composti a struttura 3-Indol-Gliossilamidica come potenziali inibitori dell’integrasi dell’HIV-1. 98
5-Arylidene-2-imino-4-thiazolidinones: Design and synthesis of novel anti-inflammatory agents 98
DECODING THE FUNCTION OF THE N-TERMINAL TAIL OF THE CELLULAR PRION PROTEIN TO INSPIRE NOVEL THERAPEUTIC AVENUES FOR NEURODEGENERATIVE DISEASES 98
Sustainable, three-component, one-pot procedure to obtain active anti-flavivirus agents 98
Computational Strategies for Discovering novel HIV-1 RT Inhibitors 96
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 96
Structural optimization of the 2-Phenyl-4-hydroxyquinoline Class of S. aureus NorA Efflux Pump Inhibitors 96
Structure-Based Pharmacophore Identification of New Chemical Scaffolds as Non–Nucleoside reverse Transcriptase Inhibitors 95
HIV-1 Integrase Inhibitors as anti-AIDS agents: Structure-Activity Relationships (SAR) of new Diketo Acids and Analogs. 95
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 95
Fighting Antimicrobial Resistance: Insights on How the Staphylococcus aureus NorA Efflux Pump Recognizes 2-Phenylquinoline Inhibitors by Supervised Molecular Dynamics (SuMD) and Molecular Docking Simulations 95
Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization 94
Pharmacophore Identification of New Chemical Scaffolds as Non-Nucleoside Reverse Transcriptase Inhibitors. 92
Modifications on C6 and C7 Positions of 3-Phenylquinolone Efflux Pump Inhibitors Led to Potent and Safe Antimycobacterial Treatment Adjuvants 92
Antagonisti noncompetitivi del recettore AMPA: progettazione, sintesi, SAR e studio del profilo farmacocinetico. 91
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor 91
PAPAIN-CATALYZED HYDROLYSIS OF ARYL ESTERS - A COMPARISON OF THE HANSCH, DOCKING AND COMFA METHODS 90
Molecular Dynamics Studies of the Wild-Type and Double Mutant HIV-1 Integrase Complexed with the 5CITEP Inhibitor: Mechanism for Inhibition and Drug Resistance 90
Functionalized sulfonyl anthranilic acid derivatives inhibit replication of all the four dengue serotypes 89
Switching the three-component Biginelli-like reaction conditions for the regioselective synthesis of new 2-amino[1,2,4]triazolo[1,5-a]pyrimidines 89
HIV-1 Integrase Inhibitors: Pharmacophore Modeling and Rational Drug Design 89
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity 89
Identification of Anti-Influenza A Compounds Inhibiting the Viral Non-Structural Protein 1 (NS1) Using a Type I Interferon-Driven Screening Strategy 87
Small Molecules Targeting DNA Polymerase Theta (POLθ) as Promising Synthetic Lethal Agents for Precision Cancer Therapy 87
Exploration of the binding mode of HIV-1 integrase strand transfer inhibitors through different computational approaches. 87
AMPA Receptor Antagonists as Potential Anticonvulsant Drugs 87
Discovery of novel HIV-1 Integrase Inhibitors: a multidisciplinary approach 86
Molecular Modeling, synthesis and SAR of anti-HIV agents. 84
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 83
Drug Design, Innoative Strategie Sintetiche e Valutazione Biologica di Nuovi Inibitori dell’Integrasi dell’HIV-1. 82
Rational design, synthesis and SAR of HIV-1 integrase Inhibitors 82
Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains 82
Discovery of a Novel and Highly Potent Noncompetitive AMPA Receptor Antagonist 81
Synthesis, resolution, stereochemistry, and molecular modeling of (R)- and (S)-2-acetyl-1-(40-chlorophenyl)-6,7-dimethoxy-1,2,3,4- tetrahydroisoquinoline AMPAR antagonists 81
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series. 81
Sintesi e SAR di inibitori dell’integrasi dell’HIV-1 a struttura 1-benzyl-1H-indolica. 80
Solution-Phase Parallel Synthesis of New DKA-Analogues as HIV-1 IN-Inhibitors. 79
DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF A SERIES OF 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONES AS DUAL INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 INTEGRASE AND THE REVERSE TRANSCRIPTASE RNASE H DOMAIN. 79
Novel targets for HIV therapy: small molecules blocking IN-LEDGF/p75 interaction 79
Cinnamoyl compounds as small-molecules inhibitors of histone acetyltransferase enzymes 79
TARGETING CDKs TO INHIBIT THE HIV-1 TAT-MEDIATED TRANSCRIPTION 79
Tetrahydroisoquinoline derivatives: a new class of non-competitive ampa receptor antagonists with potential anticonvulsant activity 78
Synthesis and anticonvulsant properties of tetrahydroisoquinoline derivatives 78
Totale 11.319
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Categoria #
all - tutte 71.808
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 71.808
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.387 0 248 33 59 95 12 18 409 68 34 176 235
2022/20232.319 196 407 76 195 172 256 3 116 760 11 81 46
2023/20241.070 57 158 36 21 17 22 177 56 177 67 123 159
2024/20252.471 16 251 80 198 241 108 281 154 495 171 303 173
2025/20265.275 375 405 265 799 581 437 840 300 575 445 169 84
2026/2027321 151 170 0 0 0 0 0 0 0 0 0 0
Totale 16.300