IRIS - Res&Arch Institutional Research Information System - Research & Archive

BARRECA, MARIA LETIZIA
 Distribuzione geografica
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Continente #
NA - Nord America 5.798
EU - Europa 4.244
AS - Asia 4.239
SA - Sud America 737
AF - Africa 130
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 4
Totale 15.160
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Nazione #
US - Stati Uniti d'America 5.692
SG - Singapore 1.718
IT - Italia 782
UA - Ucraina 736
RU - Federazione Russa 633
CN - Cina 623
VN - Vietnam 611
IE - Irlanda 595
BR - Brasile 583
HK - Hong Kong 571
SE - Svezia 327
DE - Germania 269
FR - Francia 213
FI - Finlandia 209
KR - Corea 199
GB - Regno Unito 158
IN - India 104
TR - Turchia 92
BE - Belgio 82
BD - Bangladesh 53
AR - Argentina 49
CA - Canada 43
MX - Messico 38
AT - Austria 36
IQ - Iraq 36
NL - Olanda 36
PL - Polonia 34
ZA - Sudafrica 33
UZ - Uzbekistan 31
EC - Ecuador 29
PK - Pakistan 29
JP - Giappone 28
SA - Arabia Saudita 26
CH - Svizzera 25
ES - Italia 21
ID - Indonesia 21
RO - Romania 21
PH - Filippine 19
CO - Colombia 18
CZ - Repubblica Ceca 17
MA - Marocco 17
ET - Etiopia 15
AE - Emirati Arabi Uniti 14
CL - Cile 14
TN - Tunisia 12
VE - Venezuela 12
UY - Uruguay 11
BG - Bulgaria 10
CI - Costa d'Avorio 10
AL - Albania 9
JO - Giordania 9
PY - Paraguay 9
EG - Egitto 8
KE - Kenya 8
PE - Perù 8
DZ - Algeria 7
LB - Libano 7
EU - Europa 6
PA - Panama 6
GR - Grecia 5
IL - Israele 5
IR - Iran 5
PS - Palestinian Territory 5
AO - Angola 4
KZ - Kazakistan 4
NP - Nepal 4
AM - Armenia 3
AZ - Azerbaigian 3
BO - Bolivia 3
CM - Camerun 3
DO - Repubblica Dominicana 3
HR - Croazia 3
JM - Giamaica 3
LV - Lettonia 3
MN - Mongolia 3
OM - Oman 3
SK - Slovacchia (Repubblica Slovacca) 3
SY - Repubblica araba siriana 3
BA - Bosnia-Erzegovina 2
CR - Costa Rica 2
DK - Danimarca 2
GA - Gabon 2
GD - Grenada 2
HN - Honduras 2
HU - Ungheria 2
LT - Lituania 2
MD - Moldavia 2
MU - Mauritius 2
MY - Malesia 2
NI - Nicaragua 2
NZ - Nuova Zelanda 2
RS - Serbia 2
TH - Thailandia 2
TW - Taiwan 2
XK - ???statistics.table.value.countryCode.XK??? 2
AU - Australia 1
BJ - Benin 1
BW - Botswana 1
BY - Bielorussia 1
BZ - Belize 1
Totale 15.139
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Città #
Singapore 1.266
Chandler 789
Dublin 593
Hong Kong 558
San Jose 416
Perugia 413
Jacksonville 391
Dong Ket 357
Ashburn 333
San Mateo 326
Boardman 254
Santa Clara 214
Seoul 197
Moscow 189
Medford 159
Princeton 158
Lauterbourg 151
Wilmington 132
Beijing 126
Fremont 120
Altamura 118
Los Angeles 109
Dearborn 108
The Dalles 108
Ann Arbor 100
Ho Chi Minh City 100
Andover 94
Piscataway 90
Lawrence 89
Brussels 82
São Paulo 76
New York 63
Hanoi 51
Izmir 51
Saint Petersburg 49
Des Moines 48
Munich 44
Helsinki 43
West Jordan 38
Redmond 36
Dallas 31
Hefei 30
Norwalk 29
Rome 29
Council Bluffs 28
Orem 28
Warsaw 27
Tokyo 25
Redwood City 23
San Giustino 23
Atlanta 21
Houston 21
Shanghai 21
Spoleto 21
Brooklyn 20
Johannesburg 20
Nanjing 19
Rio de Janeiro 19
Turku 19
Lappeenranta 18
Montreal 18
Columbus 16
Chennai 15
London 15
San Francisco 15
Stockholm 15
Tashkent 15
Denver 14
Kunming 14
Manchester 14
Philadelphia 14
Amsterdam 13
Belo Horizonte 13
Chicago 13
Curitiba 13
Falls Church 13
Jeddah 13
Vienna 13
Addis Ababa 12
Auburn Hills 12
Baghdad 12
Brasília 12
Changsha 12
Guangzhou 12
Guayaquil 12
Phoenix 12
Ankara 11
Poplar 11
San Paolo di Civitate 11
Abidjan 10
Buffalo 10
Haiphong 10
Recife 10
Seattle 10
Simi Valley 10
Toronto 10
Boston 9
Bucharest 9
Montevideo 9
Nuremberg 9
Totale 9.602
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Nome #
1,3-DIIDRO-BENZIMIDAZOLONI ANALOGHI: PROGETTAZIONE, SINTESI E SAR DI NUOVI INIBITORI NON-NUCLEOSIDICI DELL’RT 319
1,4-Benzothiazine ATP-Sensitive Potassium Channel Openers: Modifications at the C-2 and C-6 Positions 317
1,3-Diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 316
1,2,4-Triazolo[1,5-a]pyrimidines: Efficient One-step Synthesis and Functionalization as Influenza Polymerase PA-PB1 Interaction Disruptors 200
Alternate NF-κB-independent signaling reactivation of latent HIV-1 provirus 158
Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase 154
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors 145
New Insights on KCa3.1 Channel Modulation 142
Prion protein ligands as therapeutic agents for neurodegenerative disorders 141
3D pharmacophore models for 1,2,3,4-tetrahydroisoquinoline derivatives acting as anticonvulsant agents 141
C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors 139
A 1,8-Naphthyridone Derivative Targets the HIV-1 Tat-Mediated Transcription and Potently Inhibits the HIV-1 Replication. 138
New anti-ovarian cancer quinolone derivatives acting by modulating microRNA processing machinery 135
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists 132
2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction 132
Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development 131
A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates 130
From Quinoline to Quinazoline-Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search 129
Pharmacological inactivation of the prion protein by targeting a folding intermediate 127
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 124
A Comprehensive Structural Overview of p38 Mitogen-Activated Protein Kinase in Complex with ATP-Site and Non-ATP-Site Binders 124
Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation 124
Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase 124
A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors 123
Computer-Aided Identification of Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 115
Targeting CDKs to inhibit the HIV-1 TAT-mediated transcription 114
Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents 113
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors 112
Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions 111
From Serendipity to Rational Identification of the 5,6,7,8-Tetrahydrobenzo [4,5]thieno[2,3-d]pyrimidin-4(3H)-one Core as a New Chemotype of AKT1 Inhibitors for Acute Myeloid Leukemia 111
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B Palm Site I inhibitors case study. 110
Deciphering the molecular recognition mechanism of multidrug resistance staphylococcus aureus nora efflux pump using a supervised molecular dynamics approach 109
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 107
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 107
Co-crystal structure determination and cellular evaluation of 1,4-dihydropyrazolo[4,3-c] [1,2] benzothiazine 5,5-dioxide p38α MAPK inhibitors 107
New Pyrazolobenzothiazine Derivatives As Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors 107
Binding Mode Prediction of Strand Transfer HIV-1 Integrase Inhibitors Using Tn5 Transposase as a Plausible Surrogate Model for HIV-1 Integrase 105
p38 alpha MAPK and Type I Inhibitors: Binding Site Analysis and Use of Target Ensembles in Virtual Screening 104
A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation 103
Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors 103
Design and synthesis of NR2B Subtype-Selective Antagonist 102
Binding models of reversible inhibitors to type-B monoamine oxidase 102
Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface 102
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model. 101
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 101
Homology Modeling of AMPA Receptors: Route to the identification of noncompetitive antagonists binding site 100
Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 100
A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity 100
Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues 98
Equisetum arvense standardized dried extract hinders age-related osteosarcopenia. 97
HIV-1 Integrase strand transfer inhibitors (INSTIs): design, synthesis and biological evaluation 97
Design e Sintesi di composti a struttura 3-Indol-Gliossilamidica come potenziali inibitori dell’integrasi dell’HIV-1. 97
Binding modes of noncompetitive AMPA Antagonists: A computational approach 97
Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position 97
5-Arylidene-2-imino-4-thiazolidinones: Design and synthesis of novel anti-inflammatory agents 96
6-Aminoquinolones targeting HCV NS5B polymerase. 96
The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors 95
Sustainable, three-component, one-pot procedure to obtain active anti-flavivirus agents 95
DECODING THE FUNCTION OF THE N-TERMINAL TAIL OF THE CELLULAR PRION PROTEIN TO INSPIRE NOVEL THERAPEUTIC AVENUES FOR NEURODEGENERATIVE DISEASES 94
Structure-Based Pharmacophore Identification of New Chemical Scaffolds as Non–Nucleoside reverse Transcriptase Inhibitors 93
Computational Strategies for Discovering novel HIV-1 RT Inhibitors 93
New C-6 functionalized quinoline NorA inhibitors strongly synergize with ciprofloxacin against planktonic and biofilm growing resistant Staphylococcus aureus strains 92
HIV-1 Integrase Inhibitors as anti-AIDS agents: Structure-Activity Relationships (SAR) of new Diketo Acids and Analogs. 92
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 92
Structural optimization of the 2-Phenyl-4-hydroxyquinoline Class of S. aureus NorA Efflux Pump Inhibitors 92
Pharmacophore Identification of New Chemical Scaffolds as Non-Nucleoside Reverse Transcriptase Inhibitors. 91
Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization 91
Fighting Antimicrobial Resistance: Insights on How the Staphylococcus aureus NorA Efflux Pump Recognizes 2-Phenylquinoline Inhibitors by Supervised Molecular Dynamics (SuMD) and Molecular Docking Simulations 91
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 90
Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium 89
PAPAIN-CATALYZED HYDROLYSIS OF ARYL ESTERS - A COMPARISON OF THE HANSCH, DOCKING AND COMFA METHODS 87
Modifications on C6 and C7 Positions of 3-Phenylquinolone Efflux Pump Inhibitors Led to Potent and Safe Antimycobacterial Treatment Adjuvants 87
Switching the three-component Biginelli-like reaction conditions for the regioselective synthesis of new 2-amino[1,2,4]triazolo[1,5-a]pyrimidines 86
Molecular Dynamics Studies of the Wild-Type and Double Mutant HIV-1 Integrase Complexed with the 5CITEP Inhibitor: Mechanism for Inhibition and Drug Resistance 86
HIV-1 Integrase Inhibitors: Pharmacophore Modeling and Rational Drug Design 86
Antagonisti noncompetitivi del recettore AMPA: progettazione, sintesi, SAR e studio del profilo farmacocinetico. 86
AMPA Receptor Antagonists as Potential Anticonvulsant Drugs 86
Functionalized sulfonyl anthranilic acid derivatives inhibit replication of all the four dengue serotypes 85
Discovery of novel HIV-1 Integrase Inhibitors: a multidisciplinary approach 85
Exploration of the binding mode of HIV-1 integrase strand transfer inhibitors through different computational approaches. 85
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor 85
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity 85
Molecular Modeling, synthesis and SAR of anti-HIV agents. 84
Small Molecules Targeting DNA Polymerase Theta (POLθ) as Promising Synthetic Lethal Agents for Precision Cancer Therapy 82
Rational design, synthesis and SAR of HIV-1 integrase Inhibitors 81
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series. 81
Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains 81
Identification of Anti-Influenza A Compounds Inhibiting the Viral Non-Structural Protein 1 (NS1) Using a Type I Interferon-Driven Screening Strategy 80
Drug Design, Innoative Strategie Sintetiche e Valutazione Biologica di Nuovi Inibitori dell’Integrasi dell’HIV-1. 80
Sintesi e SAR di inibitori dell’integrasi dell’HIV-1 a struttura 1-benzyl-1H-indolica. 79
Novel targets for HIV therapy: small molecules blocking IN-LEDGF/p75 interaction 79
Synthesis, resolution, stereochemistry, and molecular modeling of (R)- and (S)-2-acetyl-1-(40-chlorophenyl)-6,7-dimethoxy-1,2,3,4- tetrahydroisoquinoline AMPAR antagonists 79
Cinnamoyl compounds as small-molecules inhibitors of histone acetyltransferase enzymes 79
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 79
Discovery of a Novel and Highly Potent Noncompetitive AMPA Receptor Antagonist 78
Solution-Phase Parallel Synthesis of New DKA-Analogues as HIV-1 IN-Inhibitors. 78
Tetrahydroisoquinoline derivatives: a new class of non-competitive ampa receptor antagonists with potential anticonvulsant activity 78
Re-evolution of the 2-phenylquinolines: Ligand-Based Design, Synthesis, and Biological Evaluation of a Potent New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors to Combat Antimicrobial Resistance 77
DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF A SERIES OF 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONES AS DUAL INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 INTEGRASE AND THE REVERSE TRANSCRIPTASE RNASE H DOMAIN. 76
Computational Strategies in Discovering Novel Non-nucleoside Inhibitors of HIV-1 RT 76
Totale 10.912
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Categoria #
all - tutte 64.289
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 64.289
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021510 0 0 0 0 0 0 0 0 0 27 110 373
2021/20221.419 32 248 33 59 95 12 18 409 68 34 176 235
2022/20232.319 196 407 76 195 172 256 3 116 760 11 81 46
2023/20241.070 57 158 36 21 17 22 177 56 177 67 123 159
2024/20252.471 16 251 80 198 241 108 281 154 495 171 303 173
2025/20264.972 375 405 265 799 581 437 840 300 575 395 0 0
Totale 15.676