IRIS - Res&Arch Institutional Research Information System - Research & Archive

BARRECA, MARIA LETIZIA
 Distribuzione geografica
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Continente #
NA - Nord America 3.887
EU - Europa 2.937
AS - Asia 1.271
AF - Africa 10
Continente sconosciuto - Info sul continente non disponibili 6
SA - Sud America 2
OC - Oceania 1
Totale 8.114
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Nazione #
US - Stati Uniti d'America 3.871
UA - Ucraina 725
IE - Irlanda 591
IT - Italia 511
VN - Vietnam 358
HK - Hong Kong 338
SE - Svezia 314
SG - Singapore 249
CN - Cina 229
DE - Germania 203
FI - Finlandia 163
RU - Federazione Russa 138
GB - Regno Unito 87
BE - Belgio 77
TR - Turchia 50
FR - Francia 32
CH - Svizzera 23
AT - Austria 17
RO - Romania 15
NL - Olanda 14
UZ - Uzbekistan 14
CA - Canada 13
KR - Corea 10
CZ - Repubblica Ceca 9
CI - Costa d'Avorio 8
IN - India 8
BG - Bulgaria 6
EU - Europa 6
JP - Giappone 6
GR - Grecia 4
LB - Libano 4
PL - Polonia 4
MX - Messico 2
PK - Pakistan 2
ZA - Sudafrica 2
AU - Australia 1
BR - Brasile 1
BZ - Belize 1
CL - Cile 1
ES - Italia 1
HU - Ungheria 1
IR - Iran 1
KH - Cambogia 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
Totale 8.114
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Città #
Chandler 789
Dublin 590
Jacksonville 388
Dong Ket 357
Hong Kong 327
San Mateo 326
Boardman 254
Perugia 217
Singapore 174
Medford 159
Princeton 158
Wilmington 132
Fremont 119
Altamura 118
Dearborn 108
Ann Arbor 100
Andover 94
Lawrence 89
Beijing 82
Brussels 77
Ashburn 69
Saint Petersburg 49
Izmir 48
Des Moines 45
West Jordan 38
Redmond 36
Norwalk 29
Helsinki 23
Redwood City 23
San Giustino 23
Los Angeles 21
Spoleto 21
Nanjing 19
Dallas 17
Rome 15
Shanghai 15
Falls Church 13
Houston 13
Kunming 13
Moscow 13
New York 13
Auburn Hills 12
Lappeenranta 11
Philadelphia 11
San Paolo di Civitate 11
Simi Valley 10
Hefei 9
Abidjan 8
Den Haag 8
Nanchang 8
Santa Clara 8
Seoul 8
Woodbridge 8
Bucharest 7
Toronto 7
Chengdu 6
Hanover 6
Mcallen 6
Olomouc 6
Xian 6
Zhengzhou 6
Jinan 5
Ottawa 5
San Diego 5
Siena 5
Timisoara 5
Washington 5
Wuhan 5
Foligno 4
Frankfurt Am Main 4
Lausanne 4
San Jose 4
Tokyo 4
Alameda 3
Fairfield 3
Guangdong 3
Guangzhou 3
Hebei 3
Ludwigshafen 3
Macerata 3
Milan 3
Modena 3
Montecarotto 3
Munich 3
Nantong 3
Tappahannock 3
Vienna 3
Baotou 2
Camerino 2
Campegine 2
Chicago 2
Edinburgh 2
Fuzhou 2
Genova 2
Gradara 2
Kiev 2
Latina 2
Leeds 2
Monmouth Junction 2
Nanning 2
Totale 5.499
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Nome #
1,3-DIIDRO-BENZIMIDAZOLONI ANALOGHI: PROGETTAZIONE, SINTESI E SAR DI NUOVI INIBITORI NON-NUCLEOSIDICI DELL’RT 236
1,3-Diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 234
1,4-Benzothiazine ATP-Sensitive Potassium Channel Openers: Modifications at the C-2 and C-6 Positions 227
Prion protein ligands as therapeutic agents for neurodegenerative disorders 105
1,2,4-Triazolo[1,5-a]pyrimidines: Efficient One-step Synthesis and Functionalization as Influenza Polymerase PA-PB1 Interaction Disruptors 101
3D pharmacophore models for 1,2,3,4-tetrahydroisoquinoline derivatives acting as anticonvulsant agents 99
Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase 86
Design e Sintesi di composti a struttura 3-Indol-Gliossilamidica come potenziali inibitori dell’integrasi dell’HIV-1. 76
Targeting CDKs to inhibit the HIV-1 TAT-mediated transcription 76
2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction 76
A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors 75
A 1,8-Naphthyridone Derivative Targets the HIV-1 Tat-Mediated Transcription and Potently Inhibits the HIV-1 Replication. 74
HIV-1 Integrase strand transfer inhibitors (INSTIs): design, synthesis and biological evaluation 72
Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development 72
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 70
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 69
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors 69
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B Palm Site I inhibitors case study. 69
Structure-Based Pharmacophore Identification of New Chemical Scaffolds as Non–Nucleoside reverse Transcriptase Inhibitors 68
Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation 68
HIV-1 Integrase Inhibitors as anti-AIDS agents: Structure-Activity Relationships (SAR) of new Diketo Acids and Analogs. 67
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 67
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors 67
Pharmacophore Identification of New Chemical Scaffolds as Non-Nucleoside Reverse Transcriptase Inhibitors. 66
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists 66
Rational design, synthesis and SAR of HIV-1 integrase Inhibitors 64
The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors 64
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 63
Homology Modeling of AMPA Receptors: Route to the identification of noncompetitive antagonists binding site 63
Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization 63
Alternate NF-κB-independent signaling reactivation of latent HIV-1 provirus 63
Deciphering the molecular recognition mechanism of multidrug resistance staphylococcus aureus nora efflux pump using a supervised molecular dynamics approach 63
Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase 63
PAPAIN-CATALYZED HYDROLYSIS OF ARYL ESTERS - A COMPARISON OF THE HANSCH, DOCKING AND COMFA METHODS 62
Discovery of novel HIV-1 Integrase Inhibitors: a multidisciplinary approach 62
New Insights on KCa3.1 Channel Modulation 62
Antagonisti noncompetitivi del recettore AMPA: progettazione, sintesi, SAR e studio del profilo farmacocinetico. 61
AMPA Receptor Antagonists as Potential Anticonvulsant Drugs 61
Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents 60
Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position 60
Sintesi e SAR di inibitori dell’integrasi dell’HIV-1 a struttura 1-benzyl-1H-indolica. 59
HIV-1 Integrase Inhibitors: Pharmacophore Modeling and Rational Drug Design 59
5-Arylidene-2-imino-4-thiazolidinones: Design and synthesis of novel anti-inflammatory agents 59
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 59
A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates 59
Binding modes of noncompetitive AMPA Antagonists: A computational approach 58
Design and synthesis of NR2B Subtype-Selective Antagonist 58
Tetrahydroisoquinoline derivatives: a new class of non-competitive ampa receptor antagonists with potential anticonvulsant activity 57
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 57
p38 alpha MAPK and Type I Inhibitors: Binding Site Analysis and Use of Target Ensembles in Virtual Screening 57
Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions 57
Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors 57
Molecular Modeling, synthesis and SAR of anti-HIV agents. 56
Exploration of the binding mode of HIV-1 integrase strand transfer inhibitors through different computational approaches. 56
Cinnamoyl compounds as small-molecules inhibitors of histone acetyltransferase enzymes 56
Computer-Aided Identification of Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 55
Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues 55
C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors 55
Molecular Dynamics Studies of the Wild-Type and Double Mutant HIV-1 Integrase Complexed with the 5CITEP Inhibitor: Mechanism for Inhibition and Drug Resistance 54
Solution-Phase Parallel Synthesis of New DKA-Analogues as HIV-1 IN-Inhibitors. 54
Computational Strategies for Discovering novel HIV-1 RT Inhibitors 54
Binding models of reversible inhibitors to type-B monoamine oxidase 54
Binding Mode Prediction of Strand Transfer HIV-1 Integrase Inhibitors Using Tn5 Transposase as a Plausible Surrogate Model for HIV-1 Integrase 54
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model. 54
Drug Design, Innoative Strategie Sintetiche e Valutazione Biologica di Nuovi Inibitori dell’Integrasi dell’HIV-1. 53
STRUCTURAL MODIFICATION OF DIKETO ACID PORTION IN 1H-BENZYLINDOLE DERIVATIVES HIV-1 INTEGRASE INHIBITORS 53
DECODING THE FUNCTION OF THE N-TERMINAL TAIL OF THE CELLULAR PRION PROTEIN TO INSPIRE NOVEL THERAPEUTIC AVENUES FOR NEURODEGENERATIVE DISEASES 51
Nuovi AMPA-Antagonisti a Struttura Tetraidroisochinolinica 50
Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 50
A Comprehensive Structural Overview of p38 Mitogen-Activated Protein Kinase in Complex with ATP-Site and Non-ATP-Site Binders 50
Molecular Modeling Studies: Discovery of Novel Potent Non-Nucleoside RT Inhibitors 49
Novel targets for HIV therapy: small molecules blocking IN-LEDGF/p75 interaction 49
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor 49
A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity 49
New Pyrazolobenzothiazine Derivatives As Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors 49
From Serendipity to Rational Identification of the 5,6,7,8-Tetrahydrobenzo [4,5]thieno[2,3-d]pyrimidin-4(3H)-one Core as a New Chemotype of AKT1 Inhibitors for Acute Myeloid Leukemia 49
Co-crystal structure determination and cellular evaluation of 1,4-dihydropyrazolo[4,3-c] [1,2] benzothiazine 5,5-dioxide p38α MAPK inhibitors 48
Discovery of 2,3-Diaryl-1,3-thiazolidin-4-ones as Potent Anti-HIV-1 Agents 47
Discovery of a Novel and Highly Potent Noncompetitive AMPA Receptor Antagonist 47
DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF A SERIES OF 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONES AS DUAL INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 INTEGRASE AND THE REVERSE TRANSCRIPTASE RNASE H DOMAIN. 47
QSAR study of anticonvulsant negative allosteric modulators of the AMPA receptor. 47
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity 47
MOLECULAR MODELING STUDIES AND SYNTHESIS FOR THE DISCOVERY OF HIV-1 IN-LEDGF/P75 INTERACTION INHIBITORS 46
Sviluppo di modello farmacoforico predittivo per gli NR2B antagonisti del recettore NMDA 46
Re-evolution of the 2-phenylquinolines: Ligand-Based Design, Synthesis, and Biological Evaluation of a Potent New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors to Combat Antimicrobial Resistance 46
6-Aminoquinolones targeting HCV NS5B polymerase. 46
PRECLINICAL EVALUATION OF 1H-BENZYLINDOLE DERIVATIVES AS NOVEL HIV INTEGRASE STRAND TRANSFER INHIBITORS 45
HIV-1-IN Strand-Transfer Inhibitors: phenyl ring exploration and synthesis of 1H-benzylindole derivative through fluorine substitutions 45
Tn5 Transposase as a useful platform to simulate HIV-1 Integrase inhibitor binding mode 45
Structure-Based Discovery of Pyrazolobenzothiazine Derivatives As Inhibitors of Hepatitis C Virus Replication 45
HIV-1 integrase inhibitors: pharmacophore modeling and rational drug design 44
Nuovo modello farmacoforico per inibitori dell’Integrasi dell’HIV-1: ottimizzazione della potenza di composti a struttura 1H-benzilindolica 44
Molecular Modeling Studies: Discovery of Novel Potent Non-Nucleoside RT Inhibitors 44
NNRTI TBZ-analoghi: progettazione razionale, sintesi e SAR 44
Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface 43
Pharmacophore-Based Design of HIV-1 Integrase Strand-Transfer Inhibitors 42
Synthesis and anticonvulsant properties of 1,2,3,4-tetrahydroisoquinolin-1-ones 42
Identificazione di Nuovi Inibitori Non-Nucleosidici della Trascrittasi Inversa dell’ HIV-1 Mediante Tecniche di Virtual screening. 42
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 42
New chemotypes to fight HCV infection: discovery of selective inhibitors of HCV replication with pyrazolobenzothiazine scaffold 41
Totale 6.318
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Categoria #
all - tutte 34.241
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 34.241
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020949 0 0 110 8 110 115 266 28 134 65 11 102
2020/20211.725 24 119 36 122 417 154 158 13 172 27 110 373
2021/20221.419 32 248 33 59 95 12 18 409 68 34 176 235
2022/20232.319 196 407 76 195 172 256 3 116 760 11 81 46
2023/20241.070 57 158 36 21 17 22 177 56 177 67 123 159
2024/2025336 16 251 69 0 0 0 0 0 0 0 0 0
Totale 8.569