IRIS - Res&Arch Institutional Research Information System - Research & Archive

BARRECA, MARIA LETIZIA
 Distribuzione geografica
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Continente #
NA - Nord America 4.099
EU - Europa 2.951
AS - Asia 1.492
AF - Africa 10
Continente sconosciuto - Info sul continente non disponibili 6
SA - Sud America 2
OC - Oceania 1
Totale 8.561
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Nazione #
US - Stati Uniti d'America 4.082
UA - Ucraina 725
IE - Irlanda 593
IT - Italia 518
SG - Singapore 454
VN - Vietnam 358
HK - Hong Kong 338
SE - Svezia 314
CN - Cina 242
DE - Germania 203
FI - Finlandia 164
RU - Federazione Russa 138
GB - Regno Unito 89
BE - Belgio 77
TR - Turchia 50
FR - Francia 32
CH - Svizzera 23
AT - Austria 18
NL - Olanda 15
RO - Romania 15
UZ - Uzbekistan 14
CA - Canada 13
KR - Corea 10
CZ - Repubblica Ceca 9
CI - Costa d'Avorio 8
IN - India 8
BG - Bulgaria 6
EU - Europa 6
JP - Giappone 6
GR - Grecia 4
LB - Libano 4
PL - Polonia 4
IR - Iran 3
MX - Messico 2
PK - Pakistan 2
ZA - Sudafrica 2
AU - Australia 1
BR - Brasile 1
BZ - Belize 1
CL - Cile 1
DO - Repubblica Dominicana 1
ES - Italia 1
HU - Ungheria 1
KH - Cambogia 1
RS - Serbia 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
Totale 8.561
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Città #
Chandler 789
Dublin 592
Jacksonville 388
Singapore 369
Dong Ket 357
Hong Kong 327
San Mateo 326
Boardman 254
Perugia 219
Santa Clara 187
Medford 159
Princeton 158
Wilmington 132
Fremont 119
Altamura 118
Dearborn 108
Ann Arbor 100
Andover 94
Lawrence 89
Beijing 83
Ashburn 80
Brussels 77
Saint Petersburg 49
Izmir 48
Des Moines 45
West Jordan 38
Redmond 36
Norwalk 29
Helsinki 24
Redwood City 23
San Giustino 23
Los Angeles 21
Spoleto 21
Nanjing 19
Dallas 17
Rome 15
Shanghai 15
Falls Church 13
Houston 13
Kunming 13
Moscow 13
New York 13
Auburn Hills 12
Lappeenranta 11
Philadelphia 11
San Paolo di Civitate 11
Simi Valley 10
Hefei 9
Abidjan 8
Den Haag 8
Nanchang 8
Seoul 8
Woodbridge 8
Bucharest 7
Toronto 7
Zhengzhou 7
Chengdu 6
Hanover 6
Mcallen 6
Olomouc 6
Xian 6
Jinan 5
Ottawa 5
San Diego 5
Siena 5
Timisoara 5
Washington 5
Wuhan 5
Foligno 4
Frankfurt Am Main 4
Guangzhou 4
Lausanne 4
Romola 4
San Jose 4
Tokyo 4
Vienna 4
Alameda 3
Fairfield 3
Guangdong 3
Hebei 3
London 3
Ludwigshafen 3
Macerata 3
Milan 3
Modena 3
Montecarotto 3
Munich 3
Nantong 3
Tappahannock 3
Baotou 2
Camerino 2
Campegine 2
Chicago 2
Edinburgh 2
Fuzhou 2
Genova 2
Gradara 2
Kiev 2
Latina 2
Leeds 2
Totale 5.896
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Nome #
1,3-DIIDRO-BENZIMIDAZOLONI ANALOGHI: PROGETTAZIONE, SINTESI E SAR DI NUOVI INIBITORI NON-NUCLEOSIDICI DELL’RT 240
1,3-Diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 238
1,4-Benzothiazine ATP-Sensitive Potassium Channel Openers: Modifications at the C-2 and C-6 Positions 230
Prion protein ligands as therapeutic agents for neurodegenerative disorders 108
1,2,4-Triazolo[1,5-a]pyrimidines: Efficient One-step Synthesis and Functionalization as Influenza Polymerase PA-PB1 Interaction Disruptors 107
3D pharmacophore models for 1,2,3,4-tetrahydroisoquinoline derivatives acting as anticonvulsant agents 105
Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase 94
Targeting CDKs to inhibit the HIV-1 TAT-mediated transcription 79
Design e Sintesi di composti a struttura 3-Indol-Gliossilamidica come potenziali inibitori dell’integrasi dell’HIV-1. 78
A 1,8-Naphthyridone Derivative Targets the HIV-1 Tat-Mediated Transcription and Potently Inhibits the HIV-1 Replication. 78
2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction 78
A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors 77
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 75
Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development 75
HIV-1 Integrase strand transfer inhibitors (INSTIs): design, synthesis and biological evaluation 74
Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation 74
Alternate NF-κB-independent signaling reactivation of latent HIV-1 provirus 74
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors 73
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 72
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B Palm Site I inhibitors case study. 72
Structure-Based Pharmacophore Identification of New Chemical Scaffolds as Non–Nucleoside reverse Transcriptase Inhibitors 70
Pharmacophore Identification of New Chemical Scaffolds as Non-Nucleoside Reverse Transcriptase Inhibitors. 70
HIV-1 Integrase Inhibitors as anti-AIDS agents: Structure-Activity Relationships (SAR) of new Diketo Acids and Analogs. 70
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors 70
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists 69
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 69
Rational design, synthesis and SAR of HIV-1 integrase Inhibitors 66
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 66
Homology Modeling of AMPA Receptors: Route to the identification of noncompetitive antagonists binding site 66
Deciphering the molecular recognition mechanism of multidrug resistance staphylococcus aureus nora efflux pump using a supervised molecular dynamics approach 66
New Insights on KCa3.1 Channel Modulation 66
The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors 65
Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization 64
A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates 64
Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase 64
PAPAIN-CATALYZED HYDROLYSIS OF ARYL ESTERS - A COMPARISON OF THE HANSCH, DOCKING AND COMFA METHODS 63
Discovery of novel HIV-1 Integrase Inhibitors: a multidisciplinary approach 63
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 63
Antagonisti noncompetitivi del recettore AMPA: progettazione, sintesi, SAR e studio del profilo farmacocinetico. 63
Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents 63
Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position 63
Design and synthesis of NR2B Subtype-Selective Antagonist 62
AMPA Receptor Antagonists as Potential Anticonvulsant Drugs 62
5-Arylidene-2-imino-4-thiazolidinones: Design and synthesis of novel anti-inflammatory agents 62
Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors 62
Sintesi e SAR di inibitori dell’integrasi dell’HIV-1 a struttura 1-benzyl-1H-indolica. 61
HIV-1 Integrase Inhibitors: Pharmacophore Modeling and Rational Drug Design 61
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 61
Binding modes of noncompetitive AMPA Antagonists: A computational approach 60
p38 alpha MAPK and Type I Inhibitors: Binding Site Analysis and Use of Target Ensembles in Virtual Screening 60
Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions 60
Exploration of the binding mode of HIV-1 integrase strand transfer inhibitors through different computational approaches. 59
C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors 59
Molecular Modeling, synthesis and SAR of anti-HIV agents. 58
Tetrahydroisoquinoline derivatives: a new class of non-competitive ampa receptor antagonists with potential anticonvulsant activity 58
Cinnamoyl compounds as small-molecules inhibitors of histone acetyltransferase enzymes 58
Computer-Aided Identification of Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 58
New Pyrazolobenzothiazine Derivatives As Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors 58
Computational Strategies for Discovering novel HIV-1 RT Inhibitors 57
Binding Mode Prediction of Strand Transfer HIV-1 Integrase Inhibitors Using Tn5 Transposase as a Plausible Surrogate Model for HIV-1 Integrase 57
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model. 57
Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues 57
Solution-Phase Parallel Synthesis of New DKA-Analogues as HIV-1 IN-Inhibitors. 56
Molecular Dynamics Studies of the Wild-Type and Double Mutant HIV-1 Integrase Complexed with the 5CITEP Inhibitor: Mechanism for Inhibition and Drug Resistance 55
Binding models of reversible inhibitors to type-B monoamine oxidase 55
DECODING THE FUNCTION OF THE N-TERMINAL TAIL OF THE CELLULAR PRION PROTEIN TO INSPIRE NOVEL THERAPEUTIC AVENUES FOR NEURODEGENERATIVE DISEASES 55
Drug Design, Innoative Strategie Sintetiche e Valutazione Biologica di Nuovi Inibitori dell’Integrasi dell’HIV-1. 54
STRUCTURAL MODIFICATION OF DIKETO ACID PORTION IN 1H-BENZYLINDOLE DERIVATIVES HIV-1 INTEGRASE INHIBITORS 54
Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 53
A Comprehensive Structural Overview of p38 Mitogen-Activated Protein Kinase in Complex with ATP-Site and Non-ATP-Site Binders 53
Nuovi AMPA-Antagonisti a Struttura Tetraidroisochinolinica 52
Novel targets for HIV therapy: small molecules blocking IN-LEDGF/p75 interaction 52
A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity 52
From Serendipity to Rational Identification of the 5,6,7,8-Tetrahydrobenzo [4,5]thieno[2,3-d]pyrimidin-4(3H)-one Core as a New Chemotype of AKT1 Inhibitors for Acute Myeloid Leukemia 52
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor 51
Co-crystal structure determination and cellular evaluation of 1,4-dihydropyrazolo[4,3-c] [1,2] benzothiazine 5,5-dioxide p38α MAPK inhibitors 51
Molecular Modeling Studies: Discovery of Novel Potent Non-Nucleoside RT Inhibitors 50
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity 50
Sviluppo di modello farmacoforico predittivo per gli NR2B antagonisti del recettore NMDA 49
Re-evolution of the 2-phenylquinolines: Ligand-Based Design, Synthesis, and Biological Evaluation of a Potent New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors to Combat Antimicrobial Resistance 49
6-Aminoquinolones targeting HCV NS5B polymerase. 49
Discovery of 2,3-Diaryl-1,3-thiazolidin-4-ones as Potent Anti-HIV-1 Agents 48
Discovery of a Novel and Highly Potent Noncompetitive AMPA Receptor Antagonist 48
DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF A SERIES OF 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONES AS DUAL INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 INTEGRASE AND THE REVERSE TRANSCRIPTASE RNASE H DOMAIN. 48
MOLECULAR MODELING STUDIES AND SYNTHESIS FOR THE DISCOVERY OF HIV-1 IN-LEDGF/P75 INTERACTION INHIBITORS 48
QSAR study of anticonvulsant negative allosteric modulators of the AMPA receptor. 48
HIV-1-IN Strand-Transfer Inhibitors: phenyl ring exploration and synthesis of 1H-benzylindole derivative through fluorine substitutions 47
Tn5 Transposase as a useful platform to simulate HIV-1 Integrase inhibitor binding mode 47
Structure-Based Discovery of Pyrazolobenzothiazine Derivatives As Inhibitors of Hepatitis C Virus Replication 47
PRECLINICAL EVALUATION OF 1H-BENZYLINDOLE DERIVATIVES AS NOVEL HIV INTEGRASE STRAND TRANSFER INHIBITORS 46
Nuovo modello farmacoforico per inibitori dell’Integrasi dell’HIV-1: ottimizzazione della potenza di composti a struttura 1H-benzilindolica 46
Molecular Modeling Studies: Discovery of Novel Potent Non-Nucleoside RT Inhibitors 46
NNRTI TBZ-analoghi: progettazione razionale, sintesi e SAR 46
Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface 46
HIV-1 integrase inhibitors: pharmacophore modeling and rational drug design 45
Identificazione di Nuovi Inibitori Non-Nucleosidici della Trascrittasi Inversa dell’ HIV-1 Mediante Tecniche di Virtual screening. 44
New chemotypes to fight HCV infection: discovery of selective inhibitors of HCV replication with pyrazolobenzothiazine scaffold 44
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 44
Pharmacological inactivation of the prion protein by targeting a folding intermediate 44
Pharmacophore-Based Design of HIV-1 Integrase Strand-Transfer Inhibitors 43
Totale 6.598
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Categoria #
all - tutte 37.392
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.392
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020831 0 0 0 0 110 115 266 28 134 65 11 102
2020/20211.725 24 119 36 122 417 154 158 13 172 27 110 373
2021/20221.419 32 248 33 59 95 12 18 409 68 34 176 235
2022/20232.319 196 407 76 195 172 256 3 116 760 11 81 46
2023/20241.070 57 158 36 21 17 22 177 56 177 67 123 159
2024/2025786 16 251 80 198 241 0 0 0 0 0 0 0
Totale 9.019