IRIS - Res&Arch Institutional Research Information System - Research & Archive

IRACI, NUNZIO
 Distribuzione geografica
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Continente #
NA - Nord America 1.911
EU - Europa 1.511
AS - Asia 757
AF - Africa 5
Continente sconosciuto - Info sul continente non disponibili 4
SA - Sud America 2
OC - Oceania 1
Totale 4.191
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Nazione #
US - Stati Uniti d'America 1.899
UA - Ucraina 356
IE - Irlanda 289
SG - Singapore 231
SE - Svezia 226
VN - Vietnam 211
IT - Italia 205
HK - Hong Kong 137
CN - Cina 121
DE - Germania 93
FI - Finlandia 88
GB - Regno Unito 83
RU - Federazione Russa 81
TR - Turchia 42
BE - Belgio 33
FR - Francia 17
CH - Svizzera 10
AT - Austria 9
CA - Canada 9
NL - Olanda 8
UZ - Uzbekistan 7
RO - Romania 5
CI - Costa d'Avorio 4
EU - Europa 4
IN - India 4
BG - Bulgaria 2
BR - Brasile 2
KR - Corea 2
BZ - Belize 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
GR - Grecia 1
HU - Ungheria 1
JP - Giappone 1
LB - Libano 1
MX - Messico 1
NZ - Nuova Zelanda 1
PL - Polonia 1
SK - Slovacchia (Repubblica Slovacca) 1
ZA - Sudafrica 1
Totale 4.191
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Città #
Chandler 349
Dublin 288
Dong Ket 211
Singapore 196
Jacksonville 190
San Mateo 180
Hong Kong 131
Perugia 103
Boardman 98
Santa Clara 82
Medford 77
Princeton 76
Andover 65
Fremont 64
Wilmington 54
Dearborn 52
Ann Arbor 48
Ashburn 48
Beijing 45
Izmir 40
Altamura 35
Brussels 32
Lawrence 30
Norwalk 23
Saint Petersburg 23
West Jordan 20
Des Moines 15
San Giustino 13
Helsinki 12
Redmond 10
Falls Church 9
Nanjing 9
Dallas 8
Moscow 8
Auburn Hills 7
Philadelphia 7
Simi Valley 7
Redwood City 6
San Diego 6
Shanghai 6
Toronto 6
Den Haag 5
Hefei 5
Lappeenranta 5
San Paolo di Civitate 5
Spoleto 5
Woodbridge 5
Zhengzhou 5
Abidjan 4
Houston 4
Los Angeles 4
Mcallen 4
New York 4
Rome 4
Chengdu 3
Hebei 3
Kunming 3
Nanchang 3
Ottawa 3
Alameda 2
Buffalo 2
Camerino 2
Fairfield 2
Frankfurt Am Main 2
Guangdong 2
Guangzhou 2
Jinan 2
Laredo 2
Munich 2
Nantong 2
Nürnberg 2
Romola 2
San Jose 2
Seoul 2
Sovicille 2
Timisoara 2
Wuhan 2
Xian 2
Atlanta 1
Baotou 1
Belize City 1
Bratislava 1
Budapest 1
Chicago 1
Dunedin 1
Edinburgh 1
Fuzhou 1
Gettysburg 1
Harbin 1
Huizingen 1
Kiev 1
Kocaeli 1
Las Vegas 1
Limbiate 1
London 1
Ludwigshafen 1
Mazzano Romano 1
Milan 1
Modena 1
Monmouth Junction 1
Totale 2.823
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Nome #
1,3-DIIDRO-BENZIMIDAZOLONI ANALOGHI: PROGETTAZIONE, SINTESI E SAR DI NUOVI INIBITORI NON-NUCLEOSIDICI DELL’RT 241
1,3-Diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 239
beta-CYCLODEXTRIN HINDERS PLGA PLASTICIZATION DURING MICROPARTICLE MANUFACTURING 135
Prion protein ligands as therapeutic agents for neurodegenerative disorders 108
Targeting CDKs to inhibit the HIV-1 TAT-mediated transcription 79
A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors 78
Design and Synthesis of DiselenoBisBenzamides (DISeBAs) as Nucleocapsid Protein 7 (NCp7) Inhibitors with anti-HIV Activity 78
Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development 76
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 73
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B Palm Site I inhibitors case study. 73
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors 71
Structure-Based Pharmacophore Identification of New Chemical Scaffolds as Non–Nucleoside reverse Transcriptase Inhibitors 70
Pharmacophore Identification of New Chemical Scaffolds as Non-Nucleoside Reverse Transcriptase Inhibitors. 70
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists 70
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 69
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 67
2-Phenylquinazolinone fragment imparts anti-CDKs and anti-HIV activities 66
Nuovi antagonisti non-competitivi del recettore NMDA/NR2B:design and sintesi 65
Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization 64
Improvement of water solubility of non-competitive AMPA receptor antagonists by complexation with beta-cyclodextrin. 63
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 63
Design and synthesis of NR2B Subtype-Selective Antagonist 62
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 61
p38 alpha MAPK and Type I Inhibitors: Binding Site Analysis and Use of Target Ensembles in Virtual Screening 61
Exploration of the binding mode of HIV-1 integrase strand transfer inhibitors through different computational approaches. 59
Design, synthesis and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents 59
New Pyrazolobenzothiazine Derivatives As Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors 59
RE-EVOLUTION OF THE 2-PHENYL-4-HYDROXYQUINOLINES: OPTIMIZATION OF A POTENT NEW CLASS OF S. AUREUS NorA EFFLUX PUMP INHIBITORS 58
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model. 58
Computer-Aided Identification of Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 58
Diselenides and benzisoselenazolones as antiproliferative agents and glutathione-S-transferase inhibitors 58
Computational Strategies for Discovering novel HIV-1 RT Inhibitors 57
Binding Mode Prediction of Strand Transfer HIV-1 Integrase Inhibitors Using Tn5 Transposase as a Plausible Surrogate Model for HIV-1 Integrase 57
DECODING THE FUNCTION OF THE N-TERMINAL TAIL OF THE CELLULAR PRION PROTEIN TO INSPIRE NOVEL THERAPEUTIC AVENUES FOR NEURODEGENERATIVE DISEASES 55
Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 53
Novel targets for HIV therapy: small molecules blocking IN-LEDGF/p75 interaction 52
Re-evolution of the 2-phenylquinolines: Ligand-Based Design, Synthesis, and Biological Evaluation of a Potent New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors to Combat Antimicrobial Resistance 50
Sviluppo di modello farmacoforico predittivo per gli NR2B antagonisti del recettore NMDA 49
MOLECULAR MODELING STUDIES AND SYNTHESIS FOR THE DISCOVERY OF HIV-1 IN-LEDGF/P75 INTERACTION INHIBITORS 48
Designed Multiple Ligands (DLMs) as innovative anti-HIV agents 48
Structure-Based Discovery of Pyrazolobenzothiazine Derivatives As Inhibitors of Hepatitis C Virus Replication 48
HIV-1-IN Strand-Transfer Inhibitors: phenyl ring exploration and synthesis of 1H-benzylindole derivative through fluorine substitutions 47
Tn5 Transposase as a useful platform to simulate HIV-1 Integrase inhibitor binding mode 47
Nuovo modello farmacoforico per inibitori dell’Integrasi dell’HIV-1: ottimizzazione della potenza di composti a struttura 1H-benzilindolica 46
Molecular Modeling Studies: Discovery of Novel Potent Non-Nucleoside RT Inhibitors 46
Identificazione di Nuovi Inibitori Non-Nucleosidici della Trascrittasi Inversa dell’ HIV-1 Mediante Tecniche di Virtual screening. 44
New chemotypes to fight HCV infection: discovery of selective inhibitors of HCV replication with pyrazolobenzothiazine scaffold 44
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 44
Docking studies on a new HIV integrase–Mg-DNA complex: phenyl ring exploration and synthesis of 1H-benzylindole derivatives through fluorine substitutions 44
Synthesis and SAR of new 1,3-dihydro-benzimidazolone analogues as non-nucleoside reverse transcriptase inhibitors (NNRTIs) 43
Pyrazolo[4,3-c][1,2]benzothiazines 5,5-Dioxide: A Promising New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors 43
Structural optimization of the 2-Phenyl-4-hydroxyquinoline Class of S. aureus NorA Efflux Pump Inhibitors 42
Studi Computazionali per l’Identificazione di Nuovi Inibitori Non-Nucleosidici della Trascrittasi Inversa dell’HIV- 41
Induced-fit docking approach provides insight into the binding mode and mechanism of action of HIV-1 integrase inhibitors. ChemMedChem 41
Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains 41
Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors”. Antiviral Research 39
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series. 39
Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitors. 39
Structure-Based Pharmacophore Identification of New Chemical Scaffolds as Non-Nucleoside Reverse Transcriptase Inhibitors. 38
Nuovi chemotipi di inibitori dell'HCV NS5B polimerasi 38
Targeting the HIV Tat-mediated transcriptional machinery: P-TEFb complex inhibitors 38
The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors 38
INTEGRASE STRAND TRANSFER INHIBITORS (INSTIs): SYNTHESIS AND ANTIVIRAL EFFETCS OF CHLORO-FLUORO SUBSTITUTIONS 37
Identification of Anti-Influenza A Compounds Inhibiting the Viral Non-Structural Protein 1 (NS1) Using a Type I Interferon-Driven Screening Strategy 35
Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. 35
Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy. 35
Progettazione, sintesi e SAR di analoghi 1,3-diidro-benzimidazoloni come nuovi agenti anti-HIV 34
Pharmacophore Modeling, Docking Experiments And Discovery Of New HIV-1 NNRTIs. 34
Rational design, synthesis and SAR of 1,3-dihydro- benzimidazolone analogues as new anti-HIV agents 33
Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents. 32
Pharmacological agents targeting the cellular prion protein 32
NCp7: targeting a multitasking protein for next-generation anti-HIV drug development part 1: covalent inhibitors 30
TARGETING CDKs TO INHIBIT THE HIV-1 TAT-MEDIATED TRANSCRIPTION 29
NCp7: Targeting a multitask protein for next-generation anti-HIV drug development part 2. Noncovalent inhibitors and nucleic acid binders 29
Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75. 29
From Small to Powerful: The Fragments Universe and its "Chem-Appeal" 25
L-arginine improves solubility and anti sars-cov-2 mpro activity of rutin but not the antiviral activity in cells 17
Totale 4.376
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Categoria #
all - tutte 17.850
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 17.850
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020280 0 0 0 0 0 0 119 15 71 27 7 41
2020/2021882 10 57 25 49 201 77 59 5 94 26 56 223
2021/2022708 16 135 12 37 47 7 5 231 27 15 88 88
2022/2023989 82 141 15 91 82 109 0 56 356 2 33 22
2023/2024481 36 62 23 11 5 8 73 35 63 29 68 68
2024/2025365 2 104 27 107 99 12 14 0 0 0 0 0
Totale 4.376