In the last decade, transition-metal catalyzed C-H functionalization reactions have progressed enormously, becoming a useful tool in organic synthesis and a practical alternative to well-established methodologies. Very recently, research efforts have also been devoted to developing more sustainable C-H functionalization protocols, in order to increase their applicability. One of the most promising approaches in this sense is represented by the substitution of common reaction media with bio-based solvents. In the present contribution a general perspective on the benefits of this approach is given, followed by key literature examples.

Towards Sustainable C−H Functionalization Reactions: The Emerging Role of Bio-Based Reaction Media

Santoro, Stefano
;
Marrocchi, Assunta;Lanari, Daniela;Vaccaro, Luigi
2018

Abstract

In the last decade, transition-metal catalyzed C-H functionalization reactions have progressed enormously, becoming a useful tool in organic synthesis and a practical alternative to well-established methodologies. Very recently, research efforts have also been devoted to developing more sustainable C-H functionalization protocols, in order to increase their applicability. One of the most promising approaches in this sense is represented by the substitution of common reaction media with bio-based solvents. In the present contribution a general perspective on the benefits of this approach is given, followed by key literature examples.
2018
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11391/1438424
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