IRIS - Res&Arch Institutional Research Information System - Research & Archive

BIAGIOLI, MICHELE
 Distribuzione geografica
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Continente #
NA - Nord America 1.992
EU - Europa 1.083
AS - Asia 766
AF - Africa 5
Continente sconosciuto - Info sul continente non disponibili 2
OC - Oceania 1
SA - Sud America 1
Totale 3.850
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Nazione #
US - Stati Uniti d'America 1.986
IT - Italia 386
IE - Irlanda 352
SG - Singapore 304
HK - Hong Kong 182
CN - Cina 135
VN - Vietnam 96
DE - Germania 54
FI - Finlandia 45
RU - Federazione Russa 40
SE - Svezia 39
FR - Francia 36
UA - Ucraina 34
GB - Regno Unito 21
BE - Belgio 19
KR - Corea 17
AT - Austria 15
CH - Svizzera 13
NL - Olanda 11
TR - Turchia 9
CA - Canada 6
LB - Libano 5
UZ - Uzbekistan 5
CI - Costa d'Avorio 4
TW - Taiwan 4
GR - Grecia 3
IR - Iran 3
PL - Polonia 3
AL - Albania 2
CZ - Repubblica Ceca 2
EU - Europa 2
SK - Slovacchia (Repubblica Slovacca) 2
AM - Armenia 1
AU - Australia 1
AZ - Azerbaigian 1
BG - Bulgaria 1
BR - Brasile 1
EE - Estonia 1
ID - Indonesia 1
IN - India 1
JP - Giappone 1
LT - Lituania 1
MA - Marocco 1
NO - Norvegia 1
PT - Portogallo 1
RO - Romania 1
SA - Arabia Saudita 1
Totale 3.850
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Città #
Chandler 501
Dublin 348
Singapore 250
San Mateo 196
Hong Kong 182
Perugia 157
Boardman 113
Santa Clara 107
Dong Ket 96
Ann Arbor 85
Medford 76
Princeton 75
Altamura 63
Lawrence 52
Wilmington 51
Dearborn 41
Andover 37
Beijing 37
Ashburn 27
Redmond 23
Brussels 18
Redwood City 18
Dallas 17
Norwalk 16
Saint Petersburg 16
Seoul 16
Los Angeles 14
Helsinki 13
Houston 12
Munich 10
Vienna 10
Den Haag 8
Florence 8
Lappeenranta 8
Cambridge 7
Chicago 7
Des Moines 6
Izmir 6
Naples 6
Rome 6
San Paolo di Civitate 6
Woodbridge 6
Lugano 5
New York 5
San Diego 5
Shanghai 5
Terni 5
Abidjan 4
Bologna 4
Jacksonville 4
Menlo Park 4
Toronto 4
Chengdu 3
Falls Church 3
Frankfurt am Main 3
Lausanne 3
Seattle 3
Acireale 2
Arzano 2
Bratislava 2
Chiyayi County 2
Esslingen am Neckar 2
Frankfurt Am Main 2
Fremont 2
Hanover 2
Hefei 2
Irpin 2
London 2
Moscow 2
Ottawa 2
Philadelphia 2
Poggio Mirteto 2
Radeberg 2
Rocca Di Papa 2
Stroncone 2
Tehran 2
Wayne 2
Xi'an 2
Zero Branco 2
Zhengzhou 2
Ankara 1
Athens 1
Avignon 1
Baku 1
Baotou 1
Bastia umbra 1
Beirut 1
Boydton 1
Brno 1
Cascina 1
Caserta 1
Castiglione del Lago 1
Cava Dei Tirreni 1
Chongqing 1
Conegliano 1
Cormeilles-en-Parisis 1
Delhi 1
Deruta 1
Ercolano 1
Fairfield 1
Totale 2.877
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Nome #
Wnt/beta-Catenin Signaling Induces Integrin alpha 4 beta 1 in T Cells and Promotes a Progressive Neuroinflammatory Disease in Mice 92
The bile acid receptor GPBAR1 regulates the M1/M2 phenotype of intestinal macrophages and activation of gpbar1 rescues mice from murine colitis 84
GILZ promotes production of peripherally induced Treg cells and mediates the crosstalk between glucocorticoids and TGF-β signaling 78
LACK OF GLUCOCORTICOID-INDUCED LEUCINE ZIPPER (GILZ) RESULTS IN B CELL LYMPHOPROLIFERATIVE DISORDER IN MICE 78
Lack of glucocorticoid-induced leucine zipper (GILZ) deregulates B-cell survival and results in B-cell lymphocytosis in mice 77
The aryl hydrocarbon receptor (AhR) mediates the counter-regulatory effects of pelargonidins in models of inflammation and metabolic dysfunctions 76
Glucocorticoid-induced leucine Zipper (GILZ) controls T lymphocytes differentation 74
GILZ REGULATES PRODUCTION OF PTREG AND TTREG CELLS AND IS NECESSARY FOR GLUCOCORTICOID-MEDIATED INDUCTION OF TREG CELLS 74
BAR501, A SELECTIVE GPBAR1 AGONIST, PROMOTES ADIPOSE TISSUE BROWNING AND AUTOPHAGY AND IMPROVES LIPID METABOLISM AND STEATO-HEPATITIS IN MICE FEED A HIGH FAT DIET 71
Identification of Cysteinyl-leukotriene-receptor 1 antagonists as ligands for the bile acid receptor GPBAR1 66
Long-glucocorticoid-induced leucine zipper (L-GILZ) expression as a new diagnostic biomarker for male infertility associated with exposure to electromagnetic fields and radiofrequency radiation. 65
Glucocorticoid and B cell development: role of Glucocorticoid-induced leucine zipper 64
Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis 64
Role of GILZ in mediating the anti-inflammatory actions of glucocorticoids 63
BAR130, A HYODEOXYCHOLIC ACID DERIVATIVE AS THE FIRST EXAMPLE OF DUAL LXR alpha/GPBAR1 AGONIST 62
Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential 62
Glucocorticoid-induced leucine Zipper (GILZ) anf the new isoform L-GILZ mediates the anti-inflammatory effects of glucocorticoids 58
The effect of Ara-C treatment on hematopoietic stem cell expasion and leukemogenesis in a mouse model of CEBPA mutant acute myeloid leukemia 58
241 - GPBAR1 (TGR5) is a Modulator of Liver Immunity and Reverses Liver Inflammation in a Mouse Models of Acute Hepatitis 57
Sa1518 – Mechanism of Acute Liver Decompensation Caused by Obeticholic Acid in Cholestasis is Fxr Dependent 57
Glucocorticoid indeced lLeucine Zipper protein (GILZ) regulates Hematopoietic stem cell engrafment and myeloid differentiation in a mouse model of CEBPA mutant acute myeloid leukemia 56
Long- Glucocrticoid induced Leucine Zipper interacts with Ras pathway and is essential for spermatogenesis 54
BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis 54
Su1053 - Bar704, a Potent and Selective Fxr Agonist Protects Against Intestinal Fibrosis 54
Glucocorticoid-induced leucine zipper regulates liver fibrosis by suppressing CCL2-mediated leukocyte recruitment 54
Genetic and Pharmacological Dissection of the Role of Spleen Tyrosine Kinase (Syk) in Intestinal Inflammation and Immune Dysfunction in Inflammatory Bowel Diseases 53
Mo2014 – Comparative Effects of Bar502, a Dual Fxr and Gpbar1 Agonist, Obeticholic Acid and Ursodeoxycholic Acid in a Rodent Model of Nash 53
Recombinant long-Glucocorticoid-induced leucine zipper (L-GILZ) protein restores the control of proliferation in gilz KO spermatogonia 52
Tu1546 – Gpbar1 is a Modulator of Liver Immunity and Its Agonism Reverses Acetaminophen-Induced Hepatotoxicity by Modulating Recruitment of Liver Macrophages 52
GILZ regulates the development of Treg cells via regulation of crosstalk between Glucocorticoids and TGF-beta 50
Metabolic variability of a multispecies probiotic preparation impacts on the anti-inflammatory activity 49
Disruption of TFG beta-SMAD3 pathway by the nuclear receptor SHP mediates the antifibrotic activities of BAR704, a novel highly selective FXR ligand 49
Tu1738 - The Aryl Hydrocarbon Receptor Mediates Anti-Inflammatory Activities of Natural and Synthetic Pelargonidines in Mouse Models of Colitis 48
Bile Acids Activated Receptors Regulate innate immunity 48
Divergent effectiveness of multispecies probiotic preparations on intestinal microbiota structure depends on metabolic properties 47
Ursodeoxycholic acid is a GPBAR1 agonist and resets liver/intestinal FXR signaling in a model of diet-induced dysbiosis and NASH 47
GPBAR1 Activation by C6-Substituted Hyodeoxycholane Analogues Protect against Colitis 47
The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity 47
Glucocorticoid-induced leucine zipper (GILZ) is involved in Th2-mediated oxazolone-induced colitis 46
Glucocorticoid-induced leucine zipper (GILZ) is a regulator of intestina immune homeostatsis and anti-inflammatory effects of glucocorticoids 46
REGULATION OF HEMATOPOIETIC STEM CELL (HSC) DEVELOPMENT: ROLE OF GLUCOCORTICOID INDUCED LEUCINE ZIPPER (GILZ) 46
Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction 46
Bile Acids Activated Receptors in Inflammatory Bowel Disease 46
Bile acids and their receptors in metabolic disorders 45
Discovery of a Novel Multi-Strains Probiotic Formulation with Improved Efficacy toward Intestinal Inflammation 44
Immunomodulatory functions of FXR 44
Opposite effects of the FXR agonist obeticholic acid on Mafg and Nrf2 mediate the development of acute liver injury in rodent models of cholestasis 43
Bile acid modulators for the treatment of nonalcoholic steatohepatitis (NASH) 43
Bile acid-activated receptors and the regulation of macrophages function in metabolic disorders 43
Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice 42
Sa1931 – Physico-Chemistry, Proteomics and In Vivo Comparative Tests to Reveal Variability in Multistrain Probiotic Formulations 42
The identification of farnesoid X receptor modulators as treatment options for non-alcoholic fatty liver disease 40
Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling 40
GPBAR1 (TGR5) LIGATION PROTECTS AGAINST COLITIS DEVELOPMENT BY REGULATING LEUKOCYTE TRAFFINKING AND PROMOTING A IL-10 DEPENDENT SHIFT IN THE M1/M2 PHENOTYPE 39
Bile Acid Signaling in Inflammatory Bowel Diseases 39
GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation 39
Tu1748 - Probiotics Beyond Taxonomy: Evidence that Anti-inflammatory Properties of Live Biotherapeutic Products Require Phenotypic Characterization 38
Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation 38
Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH 37
Glucocorticoid-Induced Leucine Zipper (GILZ) controls inflammation and tissue damage after spinal cord injury. 37
Discovery of a Potent and Orally Active Dual GPBAR1/CysLT1R Modulator for the Treatment of Metabolic Fatty Liver Disease 37
Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis 37
VARIABILITY IN INDUSTRIAL PRODUCTION AFFECTS PROBIOTICS ACTIVITY: IDENTIFICATION OF BATCHES OF PROBIOTIC VSL#3 THAT INCREASES INTESTINAL PERMEABILITY AND WORSENS COLITIS IN RODENTS 36
GPBAR1 (TGR5) AGONISM REVERSES ENDOTHELIAL DYSFUNCTION AND LIVER INJURY IN A DIETETIC MODEL OF STEATOHEPATITIS 36
Novel Isoxazole Derivatives with Potent FXR Agonistic Activity Prevent Acetaminophen-Induced Liver Injury 36
Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma 35
GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated Hepatitis 35
Bile acid activated receptors: Integrating immune and metabolic regulation in non-alcoholic fatty liver disease 34
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy 33
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma 32
Special FX: Harnessing the Farnesoid-X-Receptor to Control Bile Acid Synthesis 31
Navigation in bile acid chemical space: Discovery of novel FXR and GPBAR1 ligands 30
Combinatorial targeting of GPBAR1 and CYSLTR1 reveals a mechanistic role for bile acids and leukotrienes in drug induced liver injury 29
Future trends in the treatment of non-alcoholic steatohepatitis 29
Signaling from Intestine to the Host: How Bile Acids Regulate Intestinal and Liver Immunity 29
Beneficial effects of UDCA and norUDCA in a rodent model of steatosis are linked to modulation of GPBAR1/FXR signaling 28
Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1 26
Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G-Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease 25
Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain 25
Organoids as ex vivo culture system to investigate infection-host interaction in gastric pre-carcinogenesis 25
Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics 24
Immunephenotype Predicts Response to Vedolizumab: Integrating Clinical and Biochemical Biomarkers in the Treatment of Inflammatory Bowel Diseases 23
Discovery of a Novel Class of Dual GPBAR1 Agonists-RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders 22
Bile acids and bile acid activated receptors in the treatment of Covid-19 19
Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis 17
Activation of GPBAR1 attenuates vascular inflammation and atherosclerosis in a mouse model of NAFLD-related cardiovascular disease 17
The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer 16
Immunology of bile acids regulated receptors 13
BAR502/fibrate conjugates: synthesis, biological evaluation and metabolic profile 12
Current Landscape and Evolving Therapies for Primary Biliary Cholangitis 11
Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders 11
Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists 11
Development of dual GPBAR1 agonist and RORγt inverse agonist for the treatment of inflammatory bowel diseases 10
Modeling Inflammatory Bowel Disease by Intestinal Organoids 10
Design, Synthesis, and Pharmacological Evaluation of Dual FXR-LIFR Modulators for the Treatment of Liver Fibrosis 8
Bile Acids-Based Therapies for Primary Sclerosing Cholangitis: Current Landscape and Future Developments 8
Analysis of Oral and Gut Microbiota Composition in Children with Dental Caries by NGS Approaches 6
Microbial-derived bile acid reverses inflammation in IBD via GPBAR1 agonism and RORγt inverse agonism 3
Totale 4.086
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Categoria #
all - tutte 21.395
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.395
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020151 0 0 0 0 0 34 19 7 15 47 18 11
2020/2021402 11 16 7 14 125 22 23 18 17 26 17 106
2021/2022673 13 143 7 16 14 6 38 175 15 69 88 89
2022/20231.378 90 242 14 124 132 123 2 82 495 3 55 16
2023/2024563 31 48 20 17 22 3 141 31 31 20 122 77
2024/2025585 21 139 87 77 151 110 0 0 0 0 0 0
Totale 4.086