IRIS - Res&Arch Institutional Research Information System - Research & Archive

GORACCI, LAURA
 Distribuzione geografica
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Continente #
NA - Nord America 2.493
EU - Europa 2.200
AS - Asia 1.040
SA - Sud America 72
AF - Africa 6
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5.812
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Nazione #
US - Stati Uniti d'America 2.485
SG - Singapore 505
IT - Italia 483
IE - Irlanda 481
UA - Ucraina 265
FR - Francia 236
HK - Hong Kong 221
RU - Federazione Russa 184
CN - Cina 166
SE - Svezia 130
FI - Finlandia 123
DE - Germania 104
BR - Brasile 57
VN - Vietnam 52
GB - Regno Unito 50
KR - Corea 33
BE - Belgio 27
AT - Austria 22
NL - Olanda 19
CH - Svizzera 15
TR - Turchia 14
PL - Polonia 12
ES - Italia 10
CZ - Repubblica Ceca 8
GR - Grecia 8
LB - Libano 7
UZ - Uzbekistan 7
CA - Canada 6
JP - Giappone 6
PK - Pakistan 5
AR - Argentina 4
MA - Marocco 4
PT - Portogallo 4
AE - Emirati Arabi Uniti 3
AZ - Azerbaigian 3
EC - Ecuador 3
ID - Indonesia 3
NO - Norvegia 3
UY - Uruguay 3
BO - Bolivia 2
CL - Cile 2
CY - Cipro 2
DK - Danimarca 2
HU - Ungheria 2
IL - Israele 2
IN - India 2
IQ - Iraq 2
LA - Repubblica Popolare Democratica del Laos 2
AM - Armenia 1
BD - Bangladesh 1
BG - Bulgaria 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
CR - Costa Rica 1
EE - Estonia 1
EU - Europa 1
KW - Kuwait 1
LI - Liechtenstein 1
LK - Sri Lanka 1
LT - Lituania 1
LU - Lussemburgo 1
MC - Monaco 1
MD - Moldavia 1
MX - Messico 1
PE - Perù 1
RO - Romania 1
RS - Serbia 1
SA - Arabia Saudita 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
TN - Tunisia 1
Totale 5.812
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Città #
Chandler 506
Dublin 481
Singapore 331
Hong Kong 220
Boardman 188
Perugia 178
San Mateo 171
Jacksonville 143
Santa Clara 139
Medford 100
Princeton 100
Altamura 98
Ann Arbor 80
Lawrence 79
Wilmington 67
Andover 59
Beijing 57
Dong Ket 50
Helsinki 37
Saint Petersburg 35
Fremont 30
Moscow 30
Seoul 30
Ashburn 29
Brussels 27
Los Angeles 26
Des Moines 21
Rome 21
Nuremberg 17
Norwalk 15
San Paolo di Civitate 15
Woodbridge 15
Milan 14
Munich 14
Redmond 14
Shanghai 12
Dallas 11
Redwood City 10
New York 9
Salerno 9
Simi Valley 9
Falls Church 8
Lappeenranta 8
Tappahannock 8
Vienna 8
Belo Horizonte 6
Chicago 6
Florence 6
Istanbul 6
Auburn Hills 5
Council Bluffs 5
Izmir 5
Madrid 5
Barceloneta 4
Bologna 4
Dearborn 4
Den Haag 4
Frankfurt Am Main 4
Philadelphia 4
Phoenix 4
Portogruaro 4
Seattle 4
Siena 4
Terni 4
Tokyo 4
Trieste 4
Ankara 3
Bali 3
Edinburgh 3
Montevideo 3
Montréal 3
San Giustino 3
Serra 3
Shenzhen 3
St Louis 3
Stockholm 3
São Paulo 3
Amsterdam 2
Arezzo 2
Athens 2
Augusta 2
Baku 2
Brasília 2
Brno 2
Camerino 2
Cleveland 2
Clifton 2
Dubai 2
Falkenstein 2
Frankfurt am Main 2
Frattamaggiore 2
Gualtieri 2
Guangzhou 2
Guayaquil 2
Ho Chi Minh City 2
La Paz 2
Lahore 2
Lausanne 2
Lisbon 2
London 2
Totale 3.704
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Nome #
Attivazione di Nucleofili da Parte dello Ione Fluoruro in Presenza di Liquidi Ionici. 117
Are Carboxylic Esters Really Refractory to DAST? On the Fluorination of -Hydroxyesters with DAST. 114
BioGPS: Navigating biological space to predict polypharmacology, off-targeting, and selectivity 100
Fluorinated analogues of Bosentan: effects on the antagonist activity and the metabolic stability 91
Sintesi, Caratterizzazione e Proprietà Catalitiche di Nuovi Tensioattivi “Gemini”. 86
Interaction between DNA and Cationic Amphiphiles: a Multi-Technique Study. 86
Film Nanostrutturati di Poliammine Anfifile con Proprietà Chelanti all’Interfase Aria/Acqua 85
Lipostar, a comprehensive platform-neutral cheminformatics tool for lipidomics 84
A Multi-tecnique Investigation on Amphiphile-DNA Interactions 78
Sintesi e Caratterizzazione di Nuovi Composti Anfifilici a Testa Uridinica 77
A Broad Anti-influenza Hybrid Small Molecule that Potently Disrupts the Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits Interaction 76
Evaluating the risk of phospholipidosis using a new multidisciplinary pipeline approach 76
Structure-metabolism relationships in human-AOX: Chemical insights from a large database of aza-aromatic and amide compounds 75
Discovery and Structure–Activity Relationships of Novel ssDAF-12 Receptor Modulators 74
A role for the autophagy regulator Transcription Factor EB in amiodarone-induced phospholipidosis 72
Optimization of Small-Molecule Inhibitors of Influenza Virus Polymerase: From Thiophene-3-Carboxamide to Polyamido Scaffolds 70
Proprietà di Ammina-ossido Anfifilici all’Interfase Aria/Acqua 69
Surfactant-Based Photorheological Fluids: Effect of the Surfactant Structure 69
Synthesis and Characterization of 1,2,4-Triazolo[1,5-a]pyrimidine-2-carboxamide-based Compounds Targeting the PA-PB1 Interface of Influenza A Virus Polymerase. 68
Esterification of Aminoacids in Ionic Liquids 66
Dehydrogenation of Amines to Nitriles in Aqueous Micelles 66
Anomalous Behavior of Amine Oxide Surfactants at the Air/Water Interface 66
Improved Potency of Indole-Based NorA Efflux Pump Inhibitors: From Serendipity toward Rational Design and Development 66
Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a] pyrimidine derivatives 66
Integrating Crystallography into Early Metabolism Studies 65
A pH-Sensitive Fluorescence Probe to Study the DNA-Amine Oxide Surfactants’Interactioni 65
DNA-surfactants interaction: a multitechnical and quantitative study 64
Surfactant Based Photorheological Fluids: The Effect of Structural Changes on the Gelation Cability 64
Studi 1-H-NMR e 1H-NOESY su Matrici Gel Anfifiliche a Controllo Fotochimico 64
Langmuir monolayers of new functionalized amphiphilic systems 62
Nutritional and lipidomics biomarkers of docosahexaenoic acid-based multivitamin therapy in pediatric NASH 62
Interazioni tra sostanze anfifile e DNA: uno studio chimico-fisico e morfologico 60
Challenging AQP4 druggability for NMO-IgG antibody binding using molecular dynamics and molecular interaction fields 60
Exposition and reactivity optimization to predict sites of metabolism in chemicals Review Article 60
Liquidi Ionici come utile Mezzo di Reazione per la Preparazione di Carbonati Organici 59
GRID-Based Three-Dimensional Pharmacophores I: FLAPpharm, a Novel Approach for Pharmacophore Elucidation 59
In silico pKa Prediction and ADME Profiling 58
Synthesis of new indole-based bisphosphonates and evaluation of their chelating ability in PE/CA-PJ15 cells 58
Metabolism study and biological evaluation of bosentan derivatives 58
Decarboxylation and Dephosphorilation in new Gemini Surfactants: Changes in Aggregate Structures 57
From Experiments to a Fast Easy-to-Use Computational Methodology to Predict Human Aldehyde Oxidase Selectivity and Metabolic Reactions 57
Indole Based Weapons to Fight Antibiotic Resistance: A Structure-Activity Relationship Study 57
Synthesis and phospholipidosis effect of a series of cationic amphiphilic compounds: a case study to evaluate in silico and in vitro assays 57
Novel Nucleoside Amphiphiles as Model for DNA Based Molecular Recognition 55
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity 55
Films di Langmuir di Nuovi Sistemi Anfifilici Funzionalizzati 54
Easy and Efficient Procedure for Preparation of Symmetric Organic Carbonates in Ionic Liquid 54
Extending pKa prediction accuracy: High-throughput pKa measurements to understand pKa modulation of new chemical series 54
Passive Intestinal Absorption of Representative Plant Secondary Metabolites: A Physicochemical Study 54
Flavin Monooxygenase Metabolism: Why Medicinal Chemists Should Matter 53
Surfactant-based photorehological fluids 53
Understanding the Metabolism of Proteolysis Targeting Chimeras (PROTACs): The Next Step toward Pharmaceutical Applications 53
MARS: A Multipurpose Software for Untargeted LC–MS-Based Metabolomics and Exposomics 52
BioGPS: The Music for the Chemo- and Bioinformatics Walzer 52
LC/MS lipid profiling from human serum: a new method for global lipid extraction 52
Discovery of novel SARS-CoV-2 inhibitors targeting the main protease Mpro by virtual screenings and hit optimization 51
Metabolism of JWH-015, JWH-098, JWH-251, and JWH-307 in silico and in vitro: a pilot study for the detection of unknown synthetic cannabinoids metabolites 51
Esterification of Unprotected α-Amino Acids in Ionic Liquids as Reaction Media 50
Efficient Hydrolysis of Nitriles to Amides with Hydroperoxide Anion in Aqueous Surfactant Solutions as Reaction Medium. 50
A Novel Approach for Predicting P-Glycoprotein (ABCB1) Inhibition Using Molecular Interaction Fields 50
CROMATIC: Cross-Relationship Map of Cavities from Coronaviruses 49
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Surfactant based Photoreological Fluids: the Effect of Structural Changes on the Gelation Cability 49
Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Protein-protein Interaction as a Target for Next-generation Anti-influenza Therapeutics. 49
Modeling Phospholipidosis Induction: Reliability and Warnings 49
Automatic Identification of Lansoprazole Degradants under Stress Conditions by LC-HRMS with MassChemSite and WebChembase 49
Cyto- and enzyme toxicities of ionic liquids modelled on the basis of VolSurf+ descriptors and their principal properties 48
A novel small-molecule inhibitor of the human papillomavirus E6-p53 interaction that reactivates p53 function and blocks cancer cells growth 48
Software and Computational Tools for LC-MS-Based Epilipidomics: Challenges and Solutions 47
PROTACs bearing piperazine-containing linkers: what effect on their protonation state? 47
Hoechst 33258 as a pH Sensitive Probe to Study the Interaction of Amine Oxide Surfactants with DNA 47
Temperature Effects upon Aqueous Micellar-assisted Decarboxylation of 6-Nitrobenzisoxazole-3-carboxylate and its 5-Methyl Derivative 47
Small molecule inhibitors of influenza A and B viruses that act by disrupting subunit interactions of the viral polymerase 47
Role of mitochondria and cardiolipins in growth inhibition of breast cancer cells by retinoic acid 47
Indomethacin-based PROTACs as pan-coronavirus antiviral agents 45
Ligand-, structure- and pharmacophore-based molecular fingerprints: a case study on adenosine A1, A2A, A2B, and A3 receptor antagonists 44
α-Chymotrypsin superactivity in quaternary ammonium salts solution: kinetic and computational studies. 44
Phospholipidosis effect of drugs by adsorption into lipid monolayers 43
Computational solutions in redox lipidomics - Current strategies and future perspectives 43
Merging computational modelling and experimental metabolite identification for toxicity prediction 42
Premicellar Accelerated Decarboxylation of 6-Nitrobenzisoxazole-3-carboxylate Ion and its 5-Tetradecyloxy Derivative 41
Use of the Distribution Coefficient in Brain Polar Lipids for the Assessment of Drug-Induced Phospholipidosis Risk 41
Enhanced triacylglycerol catabolism by carboxylesterase 1 promotes aggressive colorectal carcinoma 41
New potent antibacterials against Gram-positive multiresistant pathogens: Effects of side chain modification and chirality in linezolid-like 1,2,4-oxadiazoles 40
Enabling Efficient Late-Stage Functionalization of Drug-Like Molecules with LC-MS and Reaction-Driven Data Processing 40
Prediction of retention time in reversed-phase liquid chromatography as a tool for steroid identification 40
Targeting Nsp9 as an anti-SARS-CoV-2 strategy 40
A Rational Approach for the Identification of Non-Hydroxamate HDAC6-Selective Inhibitors 39
Design, synthesis, and biological evaluation of first-in-class indomethacin-based PROTACs degrading SARS-CoV-2 main protease and with broad-spectrum antiviral activity 38
Structural Investigation of Cycloheptathiophene-3-carboxamide Derivatives Targeting Influenza Virus Polymerase Assembly 37
Modeling, design and synthesis of new heteroaryl ethylenes active against the MCF-7 breast cancer cell-line 37
A Novel Lipidomics-Based Approach to Evaluating the Risk of Clinical Hepatotoxicity Potential of Drugs in 3D Human Microtissues 36
A platelet lipidomics signature in patients with COVID-19 35
Use of lipidomics to investigate sebum dysfunction in juvenile acne 35
Synthesis and biological activity of cyclopropyl Δ7-dafachronic acids as DAF-12 receptor ligands 34
CHAPTER 18. Drug-induced Phospholipidosis 34
Delving into the Polar Lipidome by Optimized Chromatographic Separation, High-Resolution Mass Spectrometry, and Comprehensive Identification with Lipostar: Microalgae as Case Study 33
Pharmacophore-based discovery of inhibitors of a novel drug proton-antiporter in human brain endothelial hCMEC/D3 cell line 32
VHL-Modified PROteolysis TArgeting Chimeras (PROTACs) as a Strategy to Evade Metabolic Degradation in In Vitro Applications 32
MassChemSite for In-Depth Forced Degradation Analysis of PARP Inhibitors Olaparib, Rucaparib, and Niraparib 31
Totale 5.605
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Categoria #
all - tutte 31.243
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 31.243
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020156 0 0 0 0 0 0 0 0 57 64 5 30
2020/2021636 4 45 17 40 218 57 50 7 73 15 48 62
2021/2022787 11 111 21 39 21 10 30 242 33 42 94 133
2022/20231.655 119 326 34 136 121 141 3 81 605 2 68 19
2023/2024751 40 84 35 16 19 10 130 11 107 39 135 125
2024/20251.317 46 207 87 87 249 101 115 128 297 0 0 0
Totale 6.179