IRIS - Res&Arch Institutional Research Information System - Research & Archive

DATTI, Alessandro
 Distribuzione geografica
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Continente #
NA - Nord America 2.773
EU - Europa 1.987
AS - Asia 906
Continente sconosciuto - Info sul continente non disponibili 8
AF - Africa 3
SA - Sud America 3
OC - Oceania 2
Totale 5.682
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Nazione #
US - Stati Uniti d'America 2.740
UA - Ucraina 480
IE - Irlanda 475
SG - Singapore 348
SE - Svezia 290
IT - Italia 263
HK - Hong Kong 239
VN - Vietnam 175
FI - Finlandia 130
CN - Cina 100
DE - Germania 93
RU - Federazione Russa 85
FR - Francia 39
GB - Regno Unito 38
CA - Canada 29
CH - Svizzera 24
TR - Turchia 19
BE - Belgio 14
AT - Austria 11
CZ - Repubblica Ceca 9
RO - Romania 9
KR - Corea 8
EU - Europa 7
LB - Libano 6
NL - Olanda 6
UZ - Uzbekistan 6
GR - Grecia 5
PL - Polonia 5
MX - Messico 4
SK - Slovacchia (Repubblica Slovacca) 4
IQ - Iraq 3
AU - Australia 2
BG - Bulgaria 2
CL - Cile 2
EG - Egitto 2
LU - Lussemburgo 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BR - Brasile 1
DK - Danimarca 1
HR - Croazia 1
IN - India 1
MD - Moldavia 1
SA - Arabia Saudita 1
SC - Seychelles 1
Totale 5.682
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Città #
Dublin 475
Chandler 461
Singapore 272
Jacksonville 258
San Mateo 255
Hong Kong 236
Boardman 205
Dong Ket 174
Altamura 136
Santa Clara 136
Medford 122
Princeton 120
Lawrence 100
Wilmington 95
Ann Arbor 82
Redmond 78
Perugia 68
Andover 63
Beijing 44
Des Moines 42
Ashburn 38
Saint Petersburg 30
Helsinki 23
Norwalk 22
Izmir 19
Los Angeles 19
Woodbridge 19
Falls Church 16
Brussels 14
Auburn Hills 13
Dallas 12
Redwood City 12
Dearborn 11
New York 11
Moscow 9
Naples 9
San Paolo di Civitate 8
Chicago 7
Seoul 7
Brno 5
Lausanne 5
Mississauga 5
Ottawa 5
Bratislava 4
Den Haag 4
Guelph 4
Houston 4
Shanghai 4
Tappahannock 4
Toronto 4
Amelia 3
Florence 3
Karbala 3
Kiev 3
Phoenix 3
Seattle 3
Simi Valley 3
Terni 3
Al Mansurah 2
Athens 2
Bari 2
Fremont 2
Gatchina 2
Groningen 2
Lappeenranta 2
Milan 2
Mosciano Sant'Angelo 2
Nagold 2
Padova 2
Rome 2
San Giovanni in Persiceto 2
Atlanta 1
Baoding 1
Canoas 1
Chifeng 1
Chisinau 1
Chongqing 1
Dalian 1
Edinburgh 1
Esslingen am Neckar 1
Fairfield 1
Falkenstein 1
Foshan 1
Frankfurt Am Main 1
Frankfurt am Main 1
Fuzhou 1
Guangzhou 1
Gubbio 1
Haikou 1
Hamburg 1
Indianapolis 1
Janesville 1
Jinzhong 1
Kaifeng 1
Kunming 1
La Canada Flintridge 1
Las Vegas 1
Logan 1
London 1
Ludwigshafen 1
Totale 3.848
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Nome #
The anti-parasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells 93
Lysosomal enzymes in alzheimer disease and type 2 diabetes mellitus patients 89
COX inhibitors and bone: A safer impact on osteoblasts by NO-releasing NSAIDs 87
"BIOCHIMICA" Campbell Farrell 84
Implication of Cathepsins S and D in TPO+IL-16-induced commitment of hematopoietic stem cell differentiation into tolerogenic dendritic cells 83
High-Throughput Screening Identifies Cardiac Glycosides as Potent Inhibitors of Human Tissue Kallikrein Expression: Implications for Cancer Therapies 82
Lysosomal beta-Galactosidase and beta-Hexosaminidase Activities Correlate with Clinical Stages of Dementia Associated with Alzheimer's Disease and Type 2 Diabetes Mellitus 82
PhenoM: a database of morphological phenotypes caused by mutation of essential genes in Saccharomyces cerevisiae 81
A SOLID-PHASE GLYCOSYLTRANSFERASE ASSAY FOR HIGH-THROUGHPUT SCREENING IN DRUG DISCOVERY RESEARCH 80
Inhibition of the Sodium/Potassium ATPase Impairs N-Glycan Expression and Function 80
A HOMOGENEOUS CELL-BASED ASSAY TO IDENTIFY N-LINKED CARBOHYDRATE PROCESSING INHIBITORS 79
Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming 79
Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death 77
Amphotericin B stimulates secretion of β-hexosaminidase from mouse adherent spleen cells 75
High throughput kinase inhibitor screens reveal TRB3 and MAPK-ERK/TGF beta pathways as fundamental Notch regulators in breast cancer 75
Small Molecule Kinase Inhibitor Screen Identifies Polo-Like Kinase 1 as a Target for Neuroblastoma Tumor-Initiating Cells 74
An approach for fluorometric determination of glycosyltransferase activities 73
A coupled assay for UDP-GlcNAc:Galβ1-3GalNAc-R β1,6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) 73
A repurposing strategy identifies novel synergistic inhibitors of plasmodium falciparum heat shock protein 90 71
Identification of CDC25 as a Common Therapeutic Target for Triple-Negative Breast Cancer 71
Luteolin inhibition of V-ATPase a3-d2 interaction decreases osteoclast resorptive activity 70
β1,6 N-Acetylglucosaminyltransferase (core 2 GlcNAc-T) expression in normal rat tissues and different cell lines: evidence for complex mechanisms of regulation 69
A drug discovery platform to identify compounds that inhibit EGFR triple mutants 69
METHOD FOR MEASURING GLYCOSYLTRANSFERASE ACTIVITY 68
Activity levels of a beta1,6 N-acetylglucosaminyltransferase in lymphomonocytes from multiple sclerosis patients 68
Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain 68
Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors 67
Calcium ionophore A-23187 inhibits the secretion of β-hexosaminidase from the GG2EE mouse macrophage cell line 65
Amplification of a calcium channel subunit CACNG4 increases breast cancer metastasis 64
A Chemical Biology Screen Identifies Glucocorticoids as Inhibitors of C-Maf and C-Maf-Dependent Transactivation of Cyclin D2 63
A high-content chemical screen identifies ellipticine as a modulator of p53 nuclear localization 63
Blood testosterone levels are correlated with β-N-acetylhexosaminidase activity in human caput epididymis 62
A Novel Chromene-Based Pan-PI3 Kinase Inhibitor Displays Preclinical Activity in Leukemia and Myeloma 61
A Fluorescent Assay for the Determination of UDP-GlcNAc: Galβ1,3GalNAc-R (GlcNAc to GalNAc) β-1,6 N-Acetylglucosaminyltransferase Activity 60
A Small Molecule Inhibitor of D-Cyclin Transactivation Displays Preclinical Efficacy in Myeloma and Leukemia 60
STRUCTURE-FUNCTION ANALYSIS OF N-ACETYLGLUCOSAMINYLTRANSFERASE V 59
Activators of Cylindrical Proteases as Antimicrobials: Identification and Development of Small Molecule Activators of CIpP Protease 59
Spleen tyrosine kinase expression is correlated with human papillomavirus in head and neck cancer 59
A homogeneous cell-based assay to identify N-linked carbohydrate processing inhibitors 58
RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation 58
Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway 57
A solid-phase glycosyltransferase assay for high-throughput screening in drug discovery research 57
ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway 57
Anticancer activity of pyrithione zinc in oral cancer cells identified in small molecule screens and xenograft model: Implications for oral cancer therapy 56
Selenium maintains cytosolic Ca2+ homeostasis and preserves germination rates of maize pollen under H2O2 -induced oxidative stress 56
Tumor Necrosis Factor-α in Diabetic Plasma Increases the Activity of Core 2 GlcNAc-T and Adherence of Human Leukocytes to Retinal Endothelial Cells 53
Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis 53
A high throughput seeking myeloma therapeutics identifies glucocorticoids as inhibitors of c-Maf-dependent transactivation of cyclin D2 53
MicroRNA mediated lysosomal enzymes down-regulation in cell of peripheral system from aAlzheimer's disease patients 53
A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway 53
MicroRNA implications across neurodevelopment and neuropathology 53
A chemical biology screen identifies glucocorticoids that regulate c-maf expression by increasing its proteasomal degradation through up-regulation of ubiquitin 52
Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia 52
Efficient siRNA Delivery by the Cationic Liposome DOTAP in Human Hematopoietic Stem Cells Differentiating into Dendritic Cells 52
Sprouts and microgreens: Trends, opportunities, and horizons for novel research 52
Clinical validation of a link between TNF-α and the glycosylation enzyme Core 2 GlcNAc-T and the relationship of this link to diabetic retinopathy 51
Expression of cathepsins S and D signals a distinctive biochemical trait in CD34(+) hematopoietic stem cells of relapsing-remitting multiple sclerosis patients 51
Regulation of UDP-GlcNAc:Galβ1-3GalNAc-R β 1-6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) in Chinese hamster ovary cells 50
Lysosomal hydrolases in Alzheimers and type 2 diabetes mellitus patients 50
Inhibition of the Sodium Potassium Adenosine Triphosphatase Pump Sensitizes Cancer Cells to Anoikis and Prevents Distant Tumor Formation 50
Core 2 N-acetylglucosaminyltransferase activity: a diagnostic marker for Wiskott-Aldrich syndrome 49
Cathepsin S and D expression as a biochemical checkpoint for the generation of tolerogenic dendritic cells from hsc-CD34+ 49
Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming 48
Targeted Pten deletion plus p53-R270H mutation in mouse mammary epithelium induces aggressive claudin-low and basal-like breast cancer 47
Erlotinib synergizes with the poly (ADP-ribose) glycohydrolase inhibitor ethacridine in acute myeloid leukemia cells 47
Non-redundant Roles of Cathepsins L, B and S in CD1a+ Dendritic Cells Knocked-down for Cathepsin S by RNA Interference 46
Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens 45
Digitoxin-Induced Cytotoxicity in Cancer Cells Is Mediated through Distinct Kinase and Interferon Signaling Networks 45
A small molecule screening strategy with validation on human leukemia stem cells uncovers the therapeutic efficacy of kinetin riboside 45
Sorafenib as an inhibitor of ruvbl2 45
CANCER STEM CELLS AND USES THEREOF 44
β-N-acetylhexosaminidases in human cerebrospinal fluid and serum of patients with multiple sclerosis 43
Targeting neuroblastoma tumor-initiating cells: High-throughput screening strategies to identify novel chemotherapeutics 43
Defective expression of CD23 and autocrine growth-stimulation in Epstein-Barr virus (EBV)-transformed B cells from patients with Wiskott-Aldrich syndrome (WAS) 43
Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells 42
TNF-alpha in diabetic plasma increases the activity of core 2 GlcNAc-T and adherence of human leucocytes to retinal endothelial cells 42
Inhibition of osteoclast bone resorption by disrupting vacuolar H(+)-ATPase a3-B2 subunit interaction 42
Uroporphyrinogen Decarboxylase Is a Radiosensitizing Target for Head and Neck Cancer 41
Inhibition of SREBP1 sensitizes cells to death ligands 41
EVIDENCE FOR HORMONAL REGULATION OF HUMAN EXOSAMINIDASES 41
Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells 41
A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesis 41
Systematic exploration of essential yeast gene function with temperature-sensitive mutants 40
Essential Gene Profiles in Breast, Pancreatic, and Ovarian Cancer Cells 40
TUMOUR INITIATING CELLS FROM NEUROBLASTOMA, A NEURAL CREST-DERIVED TUMOR 38
A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening 38
High-throughput drug library screening identifies colchicine as a thyroid cancer inhibitor 38
HIGHLY CONSERVED CYSTEINES OF MOUSE CORE 2 BETA1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE I FORM A NETWORK OF DISULFIDE BONDS AND INCLUDE A THIOL THAT AFFECTS ENZYME ACTIVITY 38
An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14 38
Cyproheptadine displays preclinical activity in myeloma and leukemia 37
The MMS22L-TONSL Complex Mediates Recovery from Replication Stress and Homologous Recombination 37
Ibrutinib synergizes with poly(ADP-ribose) glycohydrolase inhibitors to induce cell death in AML cells via a BTK-independent mechanism 37
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities 37
The off-Patent Anti-Fungal Ciclopirox Olamine Displays Preclinical Activity in Leukemia and Myeloma 36
Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors 36
Inhibition of intracellular dipeptidyl peptidases 8 and 9 enhances parthenolide's anti-leukemic activity 35
Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K. 35
Disulfiram when combined with copper enhances the therapeutic effects of temozolomide for the treatment of glioblastoma 35
Implication of Cathepsin S and D, and of the Lysosomal Cysteine Protease Inhibitor Cystatin C during TPO+IL-16-Induced Generation of Tolerogenic Dendritic Cells from Hematopoietic Stem Cells 34
High-throughput screen identifies disulfiram as a potential therapeutic for triple-negative breast cancer cells Interaction with IQ motif-containing factors 33
Totale 5.551
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Categoria #
all - tutte 27.219
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 27.219
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020551 0 0 0 0 0 15 69 11 74 129 202 51
2020/20211.035 7 64 30 84 294 58 73 25 96 27 86 191
2021/2022986 21 168 49 62 34 14 11 314 23 29 108 153
2022/20231.663 124 303 19 131 150 184 1 77 594 1 63 16
2023/2024610 41 69 28 9 2 4 70 119 83 22 79 84
2024/2025711 11 181 28 49 351 91 0 0 0 0 0 0
Totale 6.258