IRIS - Res&Arch Institutional Research Information System - Research & Archive

DATTI, Alessandro
 Distribuzione geografica
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Continente #
NA - Nord America 2.423
EU - Europa 1.973
AS - Asia 647
Continente sconosciuto - Info sul continente non disponibili 8
AF - Africa 3
SA - Sud America 3
OC - Oceania 1
Totale 5.058
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Nazione #
US - Stati Uniti d'America 2.392
UA - Ucraina 480
IE - Irlanda 474
SE - Svezia 290
IT - Italia 258
HK - Hong Kong 236
VN - Vietnam 174
SG - Singapore 131
FI - Finlandia 128
DE - Germania 93
RU - Federazione Russa 83
CN - Cina 66
FR - Francia 38
GB - Regno Unito 38
CA - Canada 28
CH - Svizzera 24
TR - Turchia 19
BE - Belgio 14
AT - Austria 9
CZ - Repubblica Ceca 9
RO - Romania 9
KR - Corea 8
EU - Europa 7
LB - Libano 6
NL - Olanda 6
UZ - Uzbekistan 6
PL - Polonia 5
GR - Grecia 4
SK - Slovacchia (Repubblica Slovacca) 4
MX - Messico 3
BG - Bulgaria 2
CL - Cile 2
EG - Egitto 2
LU - Lussemburgo 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AU - Australia 1
BR - Brasile 1
DK - Danimarca 1
HR - Croazia 1
IN - India 1
MD - Moldavia 1
SC - Seychelles 1
Totale 5.058
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Città #
Dublin 474
Chandler 461
Jacksonville 258
San Mateo 255
Hong Kong 233
Dong Ket 174
Altamura 136
Medford 122
Princeton 120
Lawrence 100
Wilmington 95
Ann Arbor 82
Redmond 78
Singapore 72
Perugia 67
Andover 63
Beijing 43
Boardman 42
Des Moines 42
Ashburn 36
Saint Petersburg 30
Norwalk 22
Helsinki 21
Izmir 19
Woodbridge 19
Los Angeles 17
Falls Church 16
Brussels 14
Auburn Hills 13
Redwood City 12
Dearborn 11
New York 10
Moscow 9
Naples 9
San Paolo di Civitate 8
Chicago 7
Seoul 7
Brno 5
Lausanne 5
Mississauga 5
Ottawa 5
Bratislava 4
Den Haag 4
Guelph 4
Houston 4
Shanghai 4
Tappahannock 4
Amelia 3
Florence 3
Kiev 3
Phoenix 3
Seattle 3
Simi Valley 3
Terni 3
Toronto 3
Al Mansurah 2
Bari 2
Fremont 2
Groningen 2
Lappeenranta 2
Milan 2
Nagold 2
Padova 2
Rome 2
San Giovanni in Persiceto 2
Athens 1
Atlanta 1
Canoas 1
Chisinau 1
Edinburgh 1
Esslingen am Neckar 1
Fairfield 1
Falkenstein 1
Frankfurt Am Main 1
Frankfurt am Main 1
Gubbio 1
Hamburg 1
Indianapolis 1
Janesville 1
La Canada Flintridge 1
Las Vegas 1
Logan 1
London 1
Ludwigshafen 1
Mahé 1
Noisy-le-grand 1
Paris 1
San Francisco 1
San Giustino 1
San Jose 1
Sant'ilario D'enza 1
Santiago 1
Sofia 1
Stockholm 1
Trevi 1
West Palm Beach 1
Zagreb 1
Totale 3.317
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Nome #
The anti-parasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells 90
Lysosomal enzymes in alzheimer disease and type 2 diabetes mellitus patients 85
COX inhibitors and bone: A safer impact on osteoblasts by NO-releasing NSAIDs 80
High-Throughput Screening Identifies Cardiac Glycosides as Potent Inhibitors of Human Tissue Kallikrein Expression: Implications for Cancer Therapies 78
Implication of Cathepsins S and D in TPO+IL-16-induced commitment of hematopoietic stem cell differentiation into tolerogenic dendritic cells 75
Lysosomal beta-Galactosidase and beta-Hexosaminidase Activities Correlate with Clinical Stages of Dementia Associated with Alzheimer's Disease and Type 2 Diabetes Mellitus 74
PhenoM: a database of morphological phenotypes caused by mutation of essential genes in Saccharomyces cerevisiae 74
Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death 74
Inhibition of the Sodium/Potassium ATPase Impairs N-Glycan Expression and Function 73
"BIOCHIMICA" Campbell Farrell 72
High throughput kinase inhibitor screens reveal TRB3 and MAPK-ERK/TGF beta pathways as fundamental Notch regulators in breast cancer 72
A HOMOGENEOUS CELL-BASED ASSAY TO IDENTIFY N-LINKED CARBOHYDRATE PROCESSING INHIBITORS 71
A SOLID-PHASE GLYCOSYLTRANSFERASE ASSAY FOR HIGH-THROUGHPUT SCREENING IN DRUG DISCOVERY RESEARCH 71
Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming 69
Amphotericin B stimulates secretion of β-hexosaminidase from mouse adherent spleen cells 69
An approach for fluorometric determination of glycosyltransferase activities 68
Identification of CDC25 as a Common Therapeutic Target for Triple-Negative Breast Cancer 68
β1,6 N-Acetylglucosaminyltransferase (core 2 GlcNAc-T) expression in normal rat tissues and different cell lines: evidence for complex mechanisms of regulation 66
A repurposing strategy identifies novel synergistic inhibitors of plasmodium falciparum heat shock protein 90 66
Small Molecule Kinase Inhibitor Screen Identifies Polo-Like Kinase 1 as a Target for Neuroblastoma Tumor-Initiating Cells 66
METHOD FOR MEASURING GLYCOSYLTRANSFERASE ACTIVITY 65
Activity levels of a beta1,6 N-acetylglucosaminyltransferase in lymphomonocytes from multiple sclerosis patients 64
Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain 64
Luteolin inhibition of V-ATPase a3-d2 interaction decreases osteoclast resorptive activity 62
Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors 62
A coupled assay for UDP-GlcNAc:Galβ1-3GalNAc-R β1,6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) 61
Calcium ionophore A-23187 inhibits the secretion of β-hexosaminidase from the GG2EE mouse macrophage cell line 60
A drug discovery platform to identify compounds that inhibit EGFR triple mutants 59
Amplification of a calcium channel subunit CACNG4 increases breast cancer metastasis 57
A high-content chemical screen identifies ellipticine as a modulator of p53 nuclear localization 57
A Chemical Biology Screen Identifies Glucocorticoids as Inhibitors of C-Maf and C-Maf-Dependent Transactivation of Cyclin D2 56
A Small Molecule Inhibitor of D-Cyclin Transactivation Displays Preclinical Efficacy in Myeloma and Leukemia 56
Activators of Cylindrical Proteases as Antimicrobials: Identification and Development of Small Molecule Activators of CIpP Protease 56
A Fluorescent Assay for the Determination of UDP-GlcNAc: Galβ1,3GalNAc-R (GlcNAc to GalNAc) β-1,6 N-Acetylglucosaminyltransferase Activity 55
A Novel Chromene-Based Pan-PI3 Kinase Inhibitor Displays Preclinical Activity in Leukemia and Myeloma 54
STRUCTURE-FUNCTION ANALYSIS OF N-ACETYLGLUCOSAMINYLTRANSFERASE V 53
Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway 53
Anticancer activity of pyrithione zinc in oral cancer cells identified in small molecule screens and xenograft model: Implications for oral cancer therapy 53
RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation 53
Blood testosterone levels are correlated with β-N-acetylhexosaminidase activity in human caput epididymis 52
A homogeneous cell-based assay to identify N-linked carbohydrate processing inhibitors 52
A solid-phase glycosyltransferase assay for high-throughput screening in drug discovery research 52
Spleen tyrosine kinase expression is correlated with human papillomavirus in head and neck cancer 50
Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis 49
MicroRNA mediated lysosomal enzymes down-regulation in cell of peripheral system from aAlzheimer's disease patients 49
Selenium maintains cytosolic Ca2+ homeostasis and preserves germination rates of maize pollen under H2O2 -induced oxidative stress 49
MicroRNA implications across neurodevelopment and neuropathology 49
Tumor Necrosis Factor-α in Diabetic Plasma Increases the Activity of Core 2 GlcNAc-T and Adherence of Human Leukocytes to Retinal Endothelial Cells 48
Clinical validation of a link between TNF-α and the glycosylation enzyme Core 2 GlcNAc-T and the relationship of this link to diabetic retinopathy 47
A high throughput seeking myeloma therapeutics identifies glucocorticoids as inhibitors of c-Maf-dependent transactivation of cyclin D2 47
Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia 47
Expression of cathepsins S and D signals a distinctive biochemical trait in CD34(+) hematopoietic stem cells of relapsing-remitting multiple sclerosis patients 47
Regulation of UDP-GlcNAc:Galβ1-3GalNAc-R β 1-6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) in Chinese hamster ovary cells 46
A chemical biology screen identifies glucocorticoids that regulate c-maf expression by increasing its proteasomal degradation through up-regulation of ubiquitin 46
Lysosomal hydrolases in Alzheimers and type 2 diabetes mellitus patients 46
ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway 46
Core 2 N-acetylglucosaminyltransferase activity: a diagnostic marker for Wiskott-Aldrich syndrome 45
Cathepsin S and D expression as a biochemical checkpoint for the generation of tolerogenic dendritic cells from hsc-CD34+ 45
Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming 45
Targeted Pten deletion plus p53-R270H mutation in mouse mammary epithelium induces aggressive claudin-low and basal-like breast cancer 44
A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway 44
Sprouts and microgreens: Trends, opportunities, and horizons for novel research 44
Non-redundant Roles of Cathepsins L, B and S in CD1a+ Dendritic Cells Knocked-down for Cathepsin S by RNA Interference 42
Efficient siRNA Delivery by the Cationic Liposome DOTAP in Human Hematopoietic Stem Cells Differentiating into Dendritic Cells 42
Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens 41
Erlotinib synergizes with the poly (ADP-ribose) glycohydrolase inhibitor ethacridine in acute myeloid leukemia cells 41
Defective expression of CD23 and autocrine growth-stimulation in Epstein-Barr virus (EBV)-transformed B cells from patients with Wiskott-Aldrich syndrome (WAS) 40
Targeting neuroblastoma tumor-initiating cells: High-throughput screening strategies to identify novel chemotherapeutics 39
Digitoxin-Induced Cytotoxicity in Cancer Cells Is Mediated through Distinct Kinase and Interferon Signaling Networks 39
A small molecule screening strategy with validation on human leukemia stem cells uncovers the therapeutic efficacy of kinetin riboside 39
β-N-acetylhexosaminidases in human cerebrospinal fluid and serum of patients with multiple sclerosis 38
Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells 38
Uroporphyrinogen Decarboxylase Is a Radiosensitizing Target for Head and Neck Cancer 38
CANCER STEM CELLS AND USES THEREOF 37
Systematic exploration of essential yeast gene function with temperature-sensitive mutants 37
EVIDENCE FOR HORMONAL REGULATION OF HUMAN EXOSAMINIDASES 37
Essential Gene Profiles in Breast, Pancreatic, and Ovarian Cancer Cells 37
TNF-alpha in diabetic plasma increases the activity of core 2 GlcNAc-T and adherence of human leucocytes to retinal endothelial cells 36
Inhibition of SREBP1 sensitizes cells to death ligands 36
A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesis 36
Inhibition of the Sodium Potassium Adenosine Triphosphatase Pump Sensitizes Cancer Cells to Anoikis and Prevents Distant Tumor Formation 36
Inhibition of osteoclast bone resorption by disrupting vacuolar H(+)-ATPase a3-B2 subunit interaction 36
TUMOUR INITIATING CELLS FROM NEUROBLASTOMA, A NEURAL CREST-DERIVED TUMOR 35
Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells 35
The MMS22L-TONSL Complex Mediates Recovery from Replication Stress and Homologous Recombination 34
Ibrutinib synergizes with poly(ADP-ribose) glycohydrolase inhibitors to induce cell death in AML cells via a BTK-independent mechanism 34
HIGHLY CONSERVED CYSTEINES OF MOUSE CORE 2 BETA1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE I FORM A NETWORK OF DISULFIDE BONDS AND INCLUDE A THIOL THAT AFFECTS ENZYME ACTIVITY 34
Cyproheptadine displays preclinical activity in myeloma and leukemia 33
The off-Patent Anti-Fungal Ciclopirox Olamine Displays Preclinical Activity in Leukemia and Myeloma 33
Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors 33
A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening 33
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities 33
Sorafenib as an inhibitor of ruvbl2 33
Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K. 32
Implication of Cathepsin S and D, and of the Lysosomal Cysteine Protease Inhibitor Cystatin C during TPO+IL-16-Induced Generation of Tolerogenic Dendritic Cells from Hematopoietic Stem Cells 31
Inhibition of intracellular dipeptidyl peptidases 8 and 9 enhances parthenolide's anti-leukemic activity 31
Disulfiram when combined with copper enhances the therapeutic effects of temozolomide for the treatment of glioblastoma 31
High-throughput drug library screening identifies colchicine as a thyroid cancer inhibitor 31
High-throughput screen identifies disulfiram as a potential therapeutic for triple-negative breast cancer cells Interaction with IQ motif-containing factors 30
An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14 30
Totale 5.001
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Categoria #
all - tutte 22.045
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 22.045
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020725 14 9 74 11 66 15 69 11 74 129 202 51
2020/20211.035 7 64 30 84 294 58 73 25 96 27 86 191
2021/2022986 21 168 49 62 34 14 11 314 23 29 108 153
2022/20231.663 124 303 19 131 150 184 1 77 594 1 63 16
2023/2024610 41 69 28 9 2 4 70 119 83 22 79 84
2024/202511 11 0 0 0 0 0 0 0 0 0 0 0
Totale 5.558