IRIS - Res&Arch Institutional Research Information System - Research & Archive

Cellini, Barbara
 Distribuzione geografica
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Continente #
AS - Asia 2.498
NA - Nord America 2.462
EU - Europa 1.761
SA - Sud America 554
AF - Africa 61
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 1
Totale 7.342
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Nazione #
US - Stati Uniti d'America 2.390
SG - Singapore 1.368
BR - Brasile 447
IE - Irlanda 431
IT - Italia 334
RU - Federazione Russa 314
CN - Cina 307
HK - Hong Kong 280
VN - Vietnam 235
FR - Francia 124
DE - Germania 123
FI - Finlandia 116
GB - Regno Unito 64
IN - India 50
KR - Corea 48
AR - Argentina 44
RO - Romania 40
CA - Canada 33
SE - Svezia 33
UA - Ucraina 33
AT - Austria 32
BD - Bangladesh 32
TR - Turchia 32
NL - Olanda 24
MX - Messico 23
PL - Polonia 22
ES - Italia 19
UZ - Uzbekistan 19
JP - Giappone 17
CH - Svizzera 15
CO - Colombia 15
EC - Ecuador 15
IQ - Iraq 15
PK - Pakistan 14
MA - Marocco 13
SA - Arabia Saudita 12
ZA - Sudafrica 12
PH - Filippine 11
CL - Cile 10
EG - Egitto 10
ID - Indonesia 10
VE - Venezuela 10
BE - Belgio 8
LB - Libano 7
MY - Malesia 7
GR - Grecia 6
KE - Kenya 5
KZ - Kazakistan 5
BO - Bolivia 4
CZ - Repubblica Ceca 4
EU - Europa 4
JO - Giordania 4
LT - Lituania 4
NP - Nepal 4
PY - Paraguay 4
AE - Emirati Arabi Uniti 3
AZ - Azerbaigian 3
DZ - Algeria 3
ET - Etiopia 3
GE - Georgia 3
OM - Oman 3
PA - Panama 3
PE - Perù 3
TN - Tunisia 3
AL - Albania 2
BG - Bulgaria 2
CR - Costa Rica 2
EE - Estonia 2
JM - Giamaica 2
LV - Lettonia 2
MD - Moldavia 2
NI - Nicaragua 2
SV - El Salvador 2
SY - Repubblica araba siriana 2
TH - Thailandia 2
UY - Uruguay 2
AO - Angola 1
BA - Bosnia-Erzegovina 1
BF - Burkina Faso 1
BN - Brunei Darussalam 1
BW - Botswana 1
BY - Bielorussia 1
CG - Congo 1
CI - Costa d'Avorio 1
GP - Guadalupe 1
IS - Islanda 1
KN - Saint Kitts e Nevis 1
LC - Santa Lucia 1
LK - Sri Lanka 1
LU - Lussemburgo 1
LY - Libia 1
MN - Mongolia 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
PR - Porto Rico 1
PS - Palestinian Territory 1
QA - Qatar 1
SC - Seychelles 1
SI - Slovenia 1
SN - Senegal 1
Totale 7.337
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Città #
Singapore 1.045
Dublin 428
Chandler 285
Hong Kong 280
San Jose 257
Ashburn 168
San Mateo 161
Santa Clara 130
Boardman 120
Perugia 115
Moscow 99
Lauterbourg 98
Altamura 87
Medford 87
Princeton 87
Lawrence 83
Andover 72
Beijing 71
Ho Chi Minh City 66
Munich 60
Hanoi 57
Los Angeles 51
Seoul 48
The Dalles 46
Wilmington 45
São Paulo 39
Bucharest 33
New York 33
Ann Arbor 29
San Paolo di Civitate 26
Helsinki 25
Turku 25
Dong Ket 24
Saint Petersburg 22
Rio de Janeiro 21
Frankfurt am Main 20
Piscataway 19
Tokyo 17
Brooklyn 16
Nuremberg 16
Rome 16
Warsaw 16
Stockholm 15
Tashkent 15
Vienna 15
Chicago 14
Denver 14
Amsterdam 13
Belo Horizonte 13
Boston 12
Chennai 12
Council Bluffs 12
Montreal 12
Poplar 12
Norwalk 11
Curitiba 10
Dallas 10
Orem 10
Vicenza 10
Da Nang 9
Des Moines 9
Johannesburg 9
London 9
Mexico City 9
Ankara 8
Brasília 8
Columbus 8
Falls Church 8
Guangzhou 8
Hefei 8
Manchester 8
Baghdad 7
Birmingham 7
Brussels 7
Campinas 7
Haiphong 7
Phoenix 7
Redmond 7
Can Tho 6
Kocaeli 6
New Delhi 6
Novosibirsk 6
Shanghai 6
Timisoara 6
Toronto 6
Assisi 5
Atlanta 5
Falkenstein 5
Guayaquil 5
Lappeenranta 5
Mumbai 5
Nairobi 5
Quito 5
Redwood City 5
Salvador 5
Secaucus 5
Sorocaba 5
Almaty 4
Amman 4
Betim 4
Totale 4.917
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Nome #
Selectively targeting key inflammatory pathways in cystic fibrosis 139
Amniotic fluid stem cell-derived extracellular vesicles are independent metabolic units capable of modulating inflammasome activation in THP-1 cells 126
Cardiolipin-mediated temporal response to hydroquinone toxicity in human retinal pigmented epithelial cell line 120
Cyclo(His-Pro) inhibits NLRP3 inflammasome cascade in ALS microglial cells 118
Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy 115
Crosstalk between long-term sublethal oxidative stress and detrimental inflammation as potential drivers for age-related retinal degeneration 113
Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: Implications for Primary Hyperoxaluria type 1 108
The IL-17F/IL-17RC Axis Promotes Respiratory Allergy in the Proximal Airways 104
Tryptophan Co-Metabolism at the Host-Pathogen Interface 103
Astrocytes regulate the expression of Insulin-Like Growth Factor 1 Receptor (IGF1-R) in primary cortical neurons during in vitro senescence 102
Biochemical and cellular effects of a novel missense mutation of the AGXT gene associated with Primary Hyperoxaluria Type 1 99
Potential influence of cyclo(His-pro) on proteostasis: Impact on neurodegenerative diseases 97
Biochemical Characterization of Aspergillus fumigatus AroH, a Putative Aromatic Amino Acid Aminotransferase 97
Molecular basis of primary hyperoxaluria: clues to innovative treatments 97
Crystal structure of Aspergillus fumigatus AroH, an aromatic amino acid aminotransferase 93
Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study 91
Molecular and Cellular Studies Reveal Folding Defects of Human Ornithine Aminotransferase Variants Associated With Gyrate Atrophy of the Choroid and Retina 91
Identification by virtual screening and in vitro testing of human DOPA decarboxylase inhibitors. 90
Allele-specific Characterization of Alanine: Glyoxylate Aminotransferase Variants Associated with Primary Hyperoxaluria 90
Folding Defects Leading to Primary Hyperoxaluria 90
Biochemical properties and oxalate-degrading activity of oxalate decarboxylase from bacillus subtilis at neutral pH 89
Correlation between the molecular effects of mutations at the dimer interface of alanine–glyoxylate aminotransferase leading to primary hyperoxaluria type I and the cellular response to vitamin B6 87
Pyridoxal 5′-phosphate-dependent enzymes at the crossroads of host–microbe tryptophan metabolism 87
Role of misfolding in rare enzymatic deficits and use of pharmacological chaperones as therapeutic approach 87
Misfolding caused by the pathogenic mutation G47R on the minor allele of alanine:glyoxylate aminotransferase and chaperoning activity of pyridoxine 84
Biochemical analyses are instrumental in identifying the impact of mutations on holo and/or apo-forms and on the region(s) of alanine:glyoxylate aminotransferase variants associated with Primary Hyperoxaluria Type I. 84
Dimerization drives proper folding of human alanine:Glyoxylate aminotransferase but is dispensable for peroxisomal targeting 84
A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase 84
The Chaperoning Activity of Amino-oxyacetic Acid on Folding-Defective Variants of Human Alanine:Glyoxylate Aminotransferase Causing Primary Hyperoxaluria Type I 83
Pyridoxamine and pyridoxal are more effective than pyridoxine in rescuing folding-defective variants of human alanine:glyoxylate aminotransferase causing primary hyperoxaluria type I. 83
Electrostatic interactions drive native-like aggregation of human alanine:glyoxylate aminostransferase 83
Liver-directed gene therapy for ornithine aminotransferase deficiency 81
Caenorhabditis elegans AGXT-1 is a mitochondrial and temperature-adapted ortholog of peroxisomal human AGT1: New insights into between-species divergence in glyoxylate metabolism 80
The chaperone role of the pyridoxal 5′-phosphate and its implications for rare diseases involving B6-dependent enzymes 78
CRISPR/Cas9-mediated knock-out of AGXT1 in HepG2 cells as a new in vitro model of Primary Hyperoxaluria Type 1 77
A novel pathway for metabolism of the cardiovascular risk factor homoarginine by alanine:glyoxylate aminotransferase 2 77
Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses 76
Identification of Human Alanine-Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1 75
A quinonoid is an intermediate of oxidative deamination reaction catalyzed by Dopa decarboxylase 75
An engineered folded PLP-bound monomer of Treponema denticola cystalysin reveals the effect of the dimeric structure on the catalytic properties of the enzyme 74
The ILE56 mutation on different genetic backgrounds of alanine:glyoxylate aminotransferase: Clinical features and biochemical characterization 74
Biochemical and Bioinformatic Studies of Mutations of Residues at the Monomer-Monomer Interface of Human Ornithine Aminotransferase Leading to Gyrate Atrophy of Choroid and Retina 73
Molecular Dynamics-Ensemble Docking and Biophysical Studies for Structure-Based Identification of Non-Amino Acidic Ligands of DDAH-1 73
Construction, purification and characterization of untagged human liver alanine-glyoxylate aminotransferase expressed in Escherichia coli 72
Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase 71
A comprehensive picture of the mutations associated with aromatic amino acid decarboxylase deficiency: from molecular mechanisms to therapy implications 69
Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis 68
R180T variant of δ-ornithine aminotransferase associated with gyrate atrophy: biochemical, computational, X-ray and NMR studies provide insight into its catalytic features 68
Commensal fungi and oxalate degradation: is there a link? 67
Gly161 mutations associated with Primary Hyperoxaluria Type I induce the cytosolic aggregation and the intracellular degradation of the apo-form of alanine:glyoxylate aminotransferase 66
Targeting Cystalysin, a Virulence Factor of Treponema denticola-Supported Periodontitis 65
Molecular insight into the synergism between the minor allele of human liver peroxisomal alanine: Glyoxylate aminotransferase and the F152I mutation 64
Biochemical and computational approaches to improve the clinical treatment of Dopa decarboxylase-related diseases: an overview 64
Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition 64
Treponema denticola cystalysin catalyzes beta-desulfination of L-cysteine sulfinic acid and beta-decarboxylation of L-aspartate and oxalacetate 64
Molecular and cellular basis of ornithine δ-aminotransferase deficiency caused by the V332M mutation associated with gyrate atrophy of the choroid and retina 64
Use of polymer conjugates for the intraperoxisomal delivery of engineered human alanine:glyoxylate aminotransferase as a protein therapy for primary hyperoxaluria type I 64
Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications 63
Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis 63
Treponema denticola cystalysin exhibits a significant alanine racemase activity accompanied by transamination: mechanistic implications 63
Editorial: The role of cofactors in protein stability and homeostasis: Focus on human metabolism 62
Spectroscopic and kinetic analyses reveal the pyridoxal 5'-phosphate binding mode and the catalytic features of Treponema denticola cystalysin 62
Effects of interface mutations on the dimerization of alanine glyoxylate aminotransferase and implications in the mistargeting of the pathogenic variants F152I and I244T 62
Gain-of-function mutant p53 enhances mitochondrial ROS through the inhibition of PGC-1α/UCP2 axis in cancer cells 62
Characterization of C-S Lyase from C. diphtheriae: A Possible Target for New Antimicrobial Drugs 60
The N-terminal extension is essential for the formation of the active dimeric structure of liver peroxisomal alanine:glyoxylate aminotransferase 60
Harnessing inter-kingdom metabolic disparities at the human-fungal interface for novel therapeutic approaches 58
A mini-review on the international gyrate atrophy symposium 2023: More than meets the eye. Focus on outstanding research questions 58
Intracellular ascorbic acid enhances the DNA single-strand and toxicity induced by peroxynitrite in U937 cells 57
Pyridoxal 5’-Phosphate Enzymes as Targets for Therapeutic Agents 56
Rapid profiling of disease alleles using a tunable reporter of protein misfolding 56
Quercetin prevents glutathione depletion induced by dehydroascorbic acid in rabbit red blood cells 56
Primary hyperoxaluria in Italy: the past 30 years and the near future of a (not so) rare disease 55
Treatment options in primary hyperoxaluria Type I 55
S-glutathionylation exerts opposing roles in the regulation of STAT1 and STAT3 signaling in reactive microglia 55
Holo-and apocystalysin from Treponema denticola: two different conformations 54
Molecular defects of the glycine 41 variants of alanine glyoxylate aminotransferase associated with primary hyperoxaluria type I 54
A molecular journey on the pathogenesis of primary hyperoxaluria 53
S-Glutathionylation at Cys328 and Cys542 Impairs STAT3 Phosphorylation 53
Site-directed mutagenesis provides insight into racemization of alanine catlayzed by "Treponema denticola" cystalysin 53
Biochemical Studies on Human Ornithine Aminotransferase Support a Cell-Based Enzyme Replacement Therapy in the Gyrate Atrophy of the Choroid and Retina 52
Natural and unnatural compounds rescue folding defects of human alanine:glyoxylate aminotransferase leading to Primary Hyperoxaluria Type I 52
PLP-Dependent Enzymes 51
Evolutionary divergent suppressor mutations in conformational diseases 51
Extending diagnostic practices in gyrate atrophy: Enzymatic characterization and the development of an in vitro pyridoxine responsiveness assay 50
Kidney Fibrosis and Oxidative Stress: From Molecular Pathways to New Pharmacological Opportunities 49
Tat-mediated delivery of human alanine:glyoxylate aminotransferase in a cellular model of Primary Hyperoxaluria Type I 49
Molecular insights into primary hyperoxaluria Type I pathogenesis. 49
Deficit of human ornithine aminotransferase in gyrate atrophy: Molecular, cellular, and clinical aspects 49
Oligomeric State and Thermal Stability of Apo- and Holo- Human Ornithine δ-Aminotransferase 49
Molecular insights into the pathogenicity of variants associated with the aromatic amino acid decarboxylase deficiency. 49
Lysine 238 is an essential residue for alfa, beta- elimination catalyzed by "Treponema denticola" cystalysin 48
Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases. 48
Human wild-type alanine:glyoxylate aminotransferase and its naturally occurring G82E variant: functional properties and physiological implications 48
Probing the role of Tyr 64 of Treponema denticola cystalysin by site-directed mutagenesis and kinetic studies 48
Folding pathway of the pyridoxal 5'-phosphate C-S lyase MalY from Escherichia coli 48
Molecular and biochemical methods to assess the biological impact of Quantum Dots 48
S81 L and G170R mutations causing Primary Hyperoxaluria Type I in homozygosis and heterozygosis: an example of positive interallelic complementation. 48
Insights into the mechanism of oxidative deamination catalyzed by Dopa decarboxylase 47
Human liver peroxisomal alanine:glyoxylate aminotransferase: Different stability under chemical stress of the major allele, the minor allele, and its pathogenic G170R variant. 47
Totale 7.171
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Categoria #
all - tutte 36.556
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 36.556
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202136 0 0 0 0 0 0 0 0 0 7 5 24
2021/2022639 2 97 7 4 14 2 15 244 24 30 93 107
2022/20231.180 89 251 10 87 81 82 1 48 491 1 36 3
2023/2024425 33 45 18 7 21 0 57 1 22 24 88 109
2024/20251.590 14 119 47 68 182 132 76 117 300 94 290 151
2025/20263.279 249 254 240 477 428 270 625 167 307 262 0 0
Totale 7.609