IRIS - Res&Arch Institutional Research Information System - Research & Archive

Cellini, Barbara
 Distribuzione geografica
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Continente #
NA - Nord America 1.477
EU - Europa 1.015
AS - Asia 550
Continente sconosciuto - Info sul continente non disponibili 4
AF - Africa 2
SA - Sud America 1
Totale 3.049
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Nazione #
US - Stati Uniti d'America 1.476
IE - Irlanda 430
SG - Singapore 342
IT - Italia 226
CN - Cina 90
FI - Finlandia 85
RU - Federazione Russa 75
HK - Hong Kong 67
RO - Romania 40
DE - Germania 32
UA - Ucraina 30
VN - Vietnam 24
SE - Svezia 18
GB - Regno Unito 16
CH - Svizzera 13
AT - Austria 12
FR - Francia 11
TR - Turchia 8
KR - Corea 7
BE - Belgio 6
GR - Grecia 6
NL - Olanda 6
LB - Libano 5
EU - Europa 4
UZ - Uzbekistan 4
BG - Bulgaria 2
CZ - Repubblica Ceca 2
ES - Italia 2
PL - Polonia 2
CA - Canada 1
CI - Costa d'Avorio 1
EC - Ecuador 1
ID - Indonesia 1
IS - Islanda 1
MY - Malesia 1
SC - Seychelles 1
TH - Thailandia 1
Totale 3.049
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Città #
Dublin 427
Chandler 285
Singapore 284
San Mateo 161
Boardman 120
Santa Clara 110
Altamura 87
Medford 87
Princeton 87
Lawrence 83
Andover 72
Hong Kong 67
Perugia 51
Wilmington 45
Bucharest 33
Ann Arbor 29
San Paolo di Civitate 26
Dong Ket 24
Beijing 23
Saint Petersburg 22
Helsinki 21
Los Angeles 17
Norwalk 11
Des Moines 9
New York 9
Falls Church 8
Birmingham 7
Munich 7
Redmond 7
Seoul 7
Kocaeli 6
Novosibirsk 6
Timisoara 6
Brussels 5
Redwood City 5
Assisi 4
Chicago 4
Vienna 4
Woodbridge 4
Amsterdam 3
Cambridge 3
Dallas 3
Frankfurt Am Main 3
Frankfurt am Main 3
Lappeenranta 3
Milan 3
Moscow 3
Rome 3
Collazzone 2
Colle di Val d'Elsa 2
Den Haag 2
Edinburgh 2
Espoo 2
Guangzhou 2
Hanover 2
Hefei 2
Houston 2
Jacksonville 2
Kazan 2
Lausanne 2
Madrid 2
Morrovalle 2
Padova 2
Shanghai 2
Shenzhen 2
Turin 2
Urbino 2
Verona 2
Abidjan 1
Antwerp 1
Apo 1
Auxvasse 1
Bielefeld 1
Bologna 1
Brno 1
Castelfiorentino 1
Changzhou 1
Chiajna 1
Chongqing 1
Clearwater 1
Dearborn 1
Dongguan 1
Edmonton 1
Fairfield 1
Foggia 1
George Town 1
Groningen 1
Guayaquil 1
Hangzhou 1
Izmir 1
Jinan 1
Kiev 1
Leuven 1
Ludwigshafen 1
Medan 1
Menlo Park 1
Nagold 1
Nanjing 1
Nanning 1
Nice 1
Totale 2.369
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Nome #
Cyclo(His-Pro) inhibits NLRP3 inflammasome cascade in ALS microglial cells 70
Potential influence of cyclo(His-pro) on proteostasis: Impact on neurodegenerative diseases 69
Molecular basis of primary hyperoxaluria: clues to innovative treatments 61
Tryptophan Co-Metabolism at the Host-Pathogen Interface 60
Astrocytes regulate the expression of Insulin-Like Growth Factor 1 Receptor (IGF1-R) in primary cortical neurons during in vitro senescence 59
Crosstalk between long-term sublethal oxidative stress and detrimental inflammation as potential drivers for age-related retinal degeneration 55
Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: Implications for Primary Hyperoxaluria type 1 54
The IL-17F/IL-17RC Axis Promotes Respiratory Allergy in the Proximal Airways 53
Identification by virtual screening and in vitro testing of human DOPA decarboxylase inhibitors. 52
Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy 52
Selectively targeting key inflammatory pathways in cystic fibrosis 51
The Chaperoning Activity of Amino-oxyacetic Acid on Folding-Defective Variants of Human Alanine:Glyoxylate Aminotransferase Causing Primary Hyperoxaluria Type I 50
Construction, purification and characterization of untagged human liver alanine-glyoxylate aminotransferase expressed in Escherichia coli 49
Biochemical Characterization of Aspergillus fumigatus AroH, a Putative Aromatic Amino Acid Aminotransferase 48
Biochemical properties and oxalate-degrading activity of oxalate decarboxylase from bacillus subtilis at neutral pH 48
Amniotic fluid stem cell-derived extracellular vesicles are independent metabolic units capable of modulating inflammasome activation in THP-1 cells 47
Allele-specific Characterization of Alanine: Glyoxylate Aminotransferase Variants Associated with Primary Hyperoxaluria 46
Correlation between the molecular effects of mutations at the dimer interface of alanine–glyoxylate aminotransferase leading to primary hyperoxaluria type I and the cellular response to vitamin B6 44
Crystal structure of Aspergillus fumigatus AroH, an aromatic amino acid aminotransferase 43
Role of misfolding in rare enzymatic deficits and use of pharmacological chaperones as therapeutic approach 42
Pyridoxal 5′-phosphate-dependent enzymes at the crossroads of host–microbe tryptophan metabolism 41
Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications 40
Pyridoxamine and pyridoxal are more effective than pyridoxine in rescuing folding-defective variants of human alanine:glyoxylate aminotransferase causing primary hyperoxaluria type I. 40
Folding Defects Leading to Primary Hyperoxaluria 40
Gly161 mutations associated with Primary Hyperoxaluria Type I induce the cytosolic aggregation and the intracellular degradation of the apo-form of alanine:glyoxylate aminotransferase 40
The chaperone role of the pyridoxal 5′-phosphate and its implications for rare diseases involving B6-dependent enzymes 39
Characterization of C-S Lyase from C. diphtheriae: A Possible Target for New Antimicrobial Drugs 38
Electrostatic interactions drive native-like aggregation of human alanine:glyoxylate aminostransferase 38
Use of polymer conjugates for the intraperoxisomal delivery of engineered human alanine:glyoxylate aminotransferase as a protein therapy for primary hyperoxaluria type I 38
Cardiolipin-mediated temporal response to hydroquinone toxicity in human retinal pigmented epithelial cell line 37
Targeting Cystalysin, a Virulence Factor of Treponema denticola-Supported Periodontitis 37
A quinonoid is an intermediate of oxidative deamination reaction catalyzed by Dopa decarboxylase 37
Caenorhabditis elegans AGXT-1 is a mitochondrial and temperature-adapted ortholog of peroxisomal human AGT1: New insights into between-species divergence in glyoxylate metabolism 37
Biochemical and computational approaches to improve the clinical treatment of Dopa decarboxylase-related diseases: an overview 35
Biochemical analyses are instrumental in identifying the impact of mutations on holo and/or apo-forms and on the region(s) of alanine:glyoxylate aminotransferase variants associated with Primary Hyperoxaluria Type I. 35
Natural and unnatural compounds rescue folding defects of human alanine:glyoxylate aminotransferase leading to Primary Hyperoxaluria Type I 35
R180T variant of δ-ornithine aminotransferase associated with gyrate atrophy: biochemical, computational, X-ray and NMR studies provide insight into its catalytic features 34
A novel pathway for metabolism of the cardiovascular risk factor homoarginine by alanine:glyoxylate aminotransferase 2 34
Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses 33
A comprehensive picture of the mutations associated with aromatic amino acid decarboxylase deficiency: from molecular mechanisms to therapy implications 32
Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis 32
Molecular and Cellular Studies Reveal Folding Defects of Human Ornithine Aminotransferase Variants Associated With Gyrate Atrophy of the Choroid and Retina 32
Biochemical and cellular effects of a novel missense mutation of the AGXT gene associated with Primary Hyperoxaluria Type 1 31
Misfolding caused by the pathogenic mutation G47R on the minor allele of alanine:glyoxylate aminotransferase and chaperoning activity of pyridoxine 31
Effects of interface mutations on the dimerization of alanine glyoxylate aminotransferase and implications in the mistargeting of the pathogenic variants F152I and I244T 31
S-Glutathionylation at Cys328 and Cys542 Impairs STAT3 Phosphorylation 31
Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis 31
The ILE56 mutation on different genetic backgrounds of alanine:glyoxylate aminotransferase: Clinical features and biochemical characterization 31
Deficit of human ornithine aminotransferase in gyrate atrophy: Molecular, cellular, and clinical aspects 31
S-glutathionylation exerts opposing roles in the regulation of STAT1 and STAT3 signaling in reactive microglia 30
Dimerization drives proper folding of human alanine:Glyoxylate aminotransferase but is dispensable for peroxisomal targeting 30
Spectroscopic and kinetic analyses reveal the pyridoxal 5'-phosphate binding mode and the catalytic features of Treponema denticola cystalysin 29
Molecular and cellular basis of ornithine δ-aminotransferase deficiency caused by the V332M mutation associated with gyrate atrophy of the choroid and retina 29
An engineered folded PLP-bound monomer of Treponema denticola cystalysin reveals the effect of the dimeric structure on the catalytic properties of the enzyme 28
Liver peroxisomal alanine:glyoxylate aminotransferase and the effects of mutations associated with Primary Hyperoxaluria Type I: An overview. 27
Treponema denticola cystalysin catalyzes beta-desulfination of L-cysteine sulfinic acid and beta-decarboxylation of L-aspartate and oxalacetate 27
Intracellular ascorbic acid enhances the DNA single-strand and toxicity induced by peroxynitrite in U937 cells 27
A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase 27
Pyridoxal 5’-Phosphate Enzymes as Targets for Therapeutic Agents 26
Molecular defects of the glycine 41 variants of alanine glyoxylate aminotransferase associated with primary hyperoxaluria type I 26
Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases. 25
Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study 24
S250F variant associated with aromatic amino acid decarboxylase deficiency: molecular defects and intracellular rescue by pyridoxine 24
Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition 24
Folding pathway of the pyridoxal 5'-phosphate C-S lyase MalY from Escherichia coli 24
Gain-of-function mutant p53 enhances mitochondrial ROS through the inhibition of PGC-1α/UCP2 axis in cancer cells 24
Evolutionary divergent suppressor mutations in conformational diseases 24
The N-terminal extension is essential for the formation of the active dimeric structure of liver peroxisomal alanine:glyoxylate aminotransferase 24
Treponema denticola cystalysin exhibits a significant alanine racemase activity accompanied by transamination: mechanistic implications 24
Molecular insights into the pathogenicity of variants associated with the aromatic amino acid decarboxylase deficiency. 24
Tat-mediated delivery of human alanine:glyoxylate aminotransferase in a cellular model of Primary Hyperoxaluria Type I 23
PLP-Dependent Enzymes 23
Holo-and apocystalysin from Treponema denticola: two different conformations 23
Insights into the mechanism of oxidative deamination catalyzed by Dopa decarboxylase 23
Human liver peroxisomal alanine:glyoxylate aminotransferase: Different stability under chemical stress of the major allele, the minor allele, and its pathogenic G170R variant. 23
Dimerization and Folding Processes of Treponema denticola Cystalysin: The Role of Pyridoxal 5'-Phosphate 23
Site-directed mutagenesis provides insight into racemization of alanine catlayzed by "Treponema denticola" cystalysin 23
Molecular and biochemical methods to assess the biological impact of Quantum Dots 23
S81 L and G170R mutations causing Primary Hyperoxaluria Type I in homozygosis and heterozygosis: an example of positive interallelic complementation. 23
CRISPR/Cas9-mediated knock-out of AGXT1 in HepG2 cells as a new in vitro model of Primary Hyperoxaluria Type 1 22
Human wild-type alanine:glyoxylate aminotransferase and its naturally occurring G82E variant: functional properties and physiological implications 22
Human liver peroxisomal alanine:glyoxylate aminotransferase: Characterization of the two allelic forms and their pathogenic variants. 22
Interaction of Human Dopa Decarboxylase with L-Dopa: Spectroscopic and Kinetic Studies as a Function of pH 22
Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase 21
Biochemical and Bioinformatic Studies of Mutations of Residues at the Monomer-Monomer Interface of Human Ornithine Aminotransferase Leading to Gyrate Atrophy of Choroid and Retina 21
Liver-directed gene therapy for ornithine aminotransferase deficiency 21
Lysine 238 is an essential residue for alfa, beta- elimination catalyzed by "Treponema denticola" cystalysin 21
Molecular insight into the synergism between the minor allele of human liver peroxisomal alanine: Glyoxylate aminotransferase and the F152I mutation 21
Identification of Human Alanine-Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1 20
Editorial: The role of cofactors in protein stability and homeostasis: Focus on human metabolism 20
Molecular insights into primary hyperoxaluria Type I pathogenesis. 20
Treatment options in primary hyperoxaluria Type I 20
Quercetin prevents glutathione depletion induced by dehydroascorbic acid in rabbit red blood cells 20
Oligomeric State and Thermal Stability of Apo- and Holo- Human Ornithine δ-Aminotransferase 20
Probing the role of Tyr 64 of Treponema denticola cystalysin by site-directed mutagenesis and kinetic studies 19
Rapid profiling of disease alleles using a tunable reporter of protein misfolding 19
Cystalysin: an example of the catalytic versatility of pyridoxal 5'-phosphate dependent enzymes 18
Primary hyperoxaluria in Italy: the past 30 years and the near future of a (not so) rare disease 16
Commensal fungi and oxalate degradation: is there a link? 14
Extending diagnostic practices in gyrate atrophy: Enzymatic characterization and the development of an in vitro pyridoxine responsiveness assay 13
Totale 3.240
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Categoria #
all - tutte 19.834
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 19.834
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202048 0 0 0 0 0 1 2 2 12 10 18 3
2020/2021232 0 5 5 2 161 1 7 2 13 7 5 24
2021/2022639 2 97 7 4 14 2 15 244 24 30 93 107
2022/20231.180 89 251 10 87 81 82 1 48 491 1 36 3
2023/2024425 33 45 18 7 21 0 57 1 22 24 88 109
2024/2025556 14 119 47 68 182 126 0 0 0 0 0 0
Totale 3.296