IRIS - Res&Arch Institutional Research Information System - Research & Archive

Cellini, Barbara
 Distribuzione geografica
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Continente #
NA - Nord America 2.808
AS - Asia 2.649
EU - Europa 1.830
SA - Sud America 572
Continente sconosciuto - Info sul continente non disponibili 272
AF - Africa 66
OC - Oceania 1
Totale 8.198
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Nazione #
US - Stati Uniti d'America 2.683
SG - Singapore 1.391
BR - Brasile 459
IE - Irlanda 431
IT - Italia 398
CN - Cina 333
RU - Federazione Russa 314
HK - Hong Kong 288
VN - Vietnam 237
FR - Francia 127
DE - Germania 123
FI - Finlandia 116
BD - Bangladesh 113
GB - Regno Unito 64
CA - Canada 63
IN - India 52
KR - Corea 48
AR - Argentina 44
RO - Romania 40
SE - Svezia 33
TR - Turchia 33
UA - Ucraina 33
AT - Austria 32
MX - Messico 30
NL - Olanda 25
PL - Polonia 22
CO - Colombia 19
ES - Italia 19
UZ - Uzbekistan 19
JP - Giappone 18
CH - Svizzera 15
EC - Ecuador 15
IQ - Iraq 15
PK - Pakistan 14
MA - Marocco 13
ZA - Sudafrica 13
SA - Arabia Saudita 12
CL - Cile 11
PH - Filippine 11
VE - Venezuela 11
EG - Egitto 10
ID - Indonesia 10
MY - Malesia 10
BE - Belgio 8
LB - Libano 7
GR - Grecia 6
KE - Kenya 6
CR - Costa Rica 5
JM - Giamaica 5
JO - Giordania 5
KZ - Kazakistan 5
BO - Bolivia 4
CZ - Repubblica Ceca 4
EU - Europa 4
LT - Lituania 4
NP - Nepal 4
PY - Paraguay 4
SC - Seychelles 4
AE - Emirati Arabi Uniti 3
AZ - Azerbaigian 3
DZ - Algeria 3
ET - Etiopia 3
GE - Georgia 3
OM - Oman 3
PA - Panama 3
PE - Perù 3
TH - Thailandia 3
TN - Tunisia 3
TT - Trinidad e Tobago 3
AL - Albania 2
BG - Bulgaria 2
BZ - Belize 2
EE - Estonia 2
KH - Cambogia 2
LV - Lettonia 2
MD - Moldavia 2
NI - Nicaragua 2
PR - Porto Rico 2
SV - El Salvador 2
SY - Repubblica araba siriana 2
UY - Uruguay 2
AO - Angola 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BF - Burkina Faso 1
BN - Brunei Darussalam 1
BS - Bahamas 1
BW - Botswana 1
BY - Bielorussia 1
CG - Congo 1
CI - Costa d'Avorio 1
DO - Repubblica Dominicana 1
GP - Guadalupe 1
HN - Honduras 1
IS - Islanda 1
KN - Saint Kitts e Nevis 1
KY - Cayman, isole 1
LC - Santa Lucia 1
LK - Sri Lanka 1
LU - Lussemburgo 1
Totale 7.918
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Città #
Singapore 1.055
Dublin 428
San Jose 295
Hong Kong 288
Chandler 285
Ashburn 192
San Mateo 161
Santa Clara 148
Boardman 120
Perugia 115
Moscow 99
Lauterbourg 98
Altamura 87
Medford 87
Princeton 87
Lawrence 83
Beijing 80
Andover 72
Ho Chi Minh City 67
Los Angeles 61
Munich 60
Hanoi 57
Seoul 48
Wilmington 47
The Dalles 46
New York 44
São Paulo 41
Bucharest 33
Ann Arbor 29
San Paolo di Civitate 26
Helsinki 25
Turku 25
Dong Ket 24
Piscataway 23
Rio de Janeiro 23
Rome 23
Saint Petersburg 22
Frankfurt am Main 20
Brooklyn 19
Montreal 17
Tokyo 17
Chicago 16
Nuremberg 16
Warsaw 16
Stockholm 15
Tashkent 15
Vienna 15
Denver 14
Mexico City 14
Amsterdam 13
Belo Horizonte 13
Dallas 13
Boston 12
Chennai 12
Council Bluffs 12
Poplar 12
Toronto 12
Norwalk 11
Phoenix 11
Curitiba 10
London 10
Milan 10
Orem 10
Vicenza 10
Brasília 9
Da Nang 9
Des Moines 9
Johannesburg 9
Shanghai 9
Ankara 8
Atlanta 8
Columbus 8
Falls Church 8
Guangzhou 8
Hefei 8
Manchester 8
Turin 8
Baghdad 7
Birmingham 7
Brussels 7
Buffalo 7
Campinas 7
Haiphong 7
Redmond 7
Assisi 6
Can Tho 6
Charlotte 6
Houston 6
Kocaeli 6
Mumbai 6
Nairobi 6
New Delhi 6
Novosibirsk 6
Timisoara 6
Cincinnati 5
Falkenstein 5
Guayaquil 5
Lappeenranta 5
Miami 5
Philadelphia 5
Totale 5.117
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Nome #
Selectively targeting key inflammatory pathways in cystic fibrosis 145
Biochemical Studies on Human Ornithine Aminotransferase Support a Cell-Based Enzyme Replacement Therapy in the Gyrate Atrophy of the Choroid and Retina 135
Amniotic fluid stem cell-derived extracellular vesicles are independent metabolic units capable of modulating inflammasome activation in THP-1 cells 134
Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy 127
Cardiolipin-mediated temporal response to hydroquinone toxicity in human retinal pigmented epithelial cell line 126
Biochemical Characterization of Aspergillus fumigatus AroH, a Putative Aromatic Amino Acid Aminotransferase 119
Cyclo(His-Pro) inhibits NLRP3 inflammasome cascade in ALS microglial cells 118
Crosstalk between long-term sublethal oxidative stress and detrimental inflammation as potential drivers for age-related retinal degeneration 116
Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: Implications for Primary Hyperoxaluria type 1 112
Tryptophan Co-Metabolism at the Host-Pathogen Interface 108
Astrocytes regulate the expression of Insulin-Like Growth Factor 1 Receptor (IGF1-R) in primary cortical neurons during in vitro senescence 106
Molecular basis of primary hyperoxaluria: clues to innovative treatments 106
The IL-17F/IL-17RC Axis Promotes Respiratory Allergy in the Proximal Airways 105
Biochemical and cellular effects of a novel missense mutation of the AGXT gene associated with Primary Hyperoxaluria Type 1 103
Potential influence of cyclo(His-pro) on proteostasis: Impact on neurodegenerative diseases 100
Crystal structure of Aspergillus fumigatus AroH, an aromatic amino acid aminotransferase 97
Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study 96
Pyridoxamine and pyridoxal are more effective than pyridoxine in rescuing folding-defective variants of human alanine:glyoxylate aminotransferase causing primary hyperoxaluria type I. 96
Folding Defects Leading to Primary Hyperoxaluria 95
Molecular and Cellular Studies Reveal Folding Defects of Human Ornithine Aminotransferase Variants Associated With Gyrate Atrophy of the Choroid and Retina 94
Dimerization drives proper folding of human alanine:Glyoxylate aminotransferase but is dispensable for peroxisomal targeting 94
Identification by virtual screening and in vitro testing of human DOPA decarboxylase inhibitors. 93
Biochemical properties and oxalate-degrading activity of oxalate decarboxylase from bacillus subtilis at neutral pH 93
Misfolding caused by the pathogenic mutation G47R on the minor allele of alanine:glyoxylate aminotransferase and chaperoning activity of pyridoxine 92
Allele-specific Characterization of Alanine: Glyoxylate Aminotransferase Variants Associated with Primary Hyperoxaluria 92
Caenorhabditis elegans AGXT-1 is a mitochondrial and temperature-adapted ortholog of peroxisomal human AGT1: New insights into between-species divergence in glyoxylate metabolism 92
Role of misfolding in rare enzymatic deficits and use of pharmacological chaperones as therapeutic approach 91
A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase 91
Pyridoxal 5′-phosphate-dependent enzymes at the crossroads of host–microbe tryptophan metabolism 90
CRISPR/Cas9-mediated knock-out of AGXT1 in HepG2 cells as a new in vitro model of Primary Hyperoxaluria Type 1 89
Liver-directed gene therapy for ornithine aminotransferase deficiency 88
Correlation between the molecular effects of mutations at the dimer interface of alanine–glyoxylate aminotransferase leading to primary hyperoxaluria type I and the cellular response to vitamin B6 88
Biochemical analyses are instrumental in identifying the impact of mutations on holo and/or apo-forms and on the region(s) of alanine:glyoxylate aminotransferase variants associated with Primary Hyperoxaluria Type I. 85
Electrostatic interactions drive native-like aggregation of human alanine:glyoxylate aminostransferase 85
The Chaperoning Activity of Amino-oxyacetic Acid on Folding-Defective Variants of Human Alanine:Glyoxylate Aminotransferase Causing Primary Hyperoxaluria Type I 83
Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses 82
The ILE56 mutation on different genetic backgrounds of alanine:glyoxylate aminotransferase: Clinical features and biochemical characterization 82
A novel pathway for metabolism of the cardiovascular risk factor homoarginine by alanine:glyoxylate aminotransferase 2 81
Molecular Dynamics-Ensemble Docking and Biophysical Studies for Structure-Based Identification of Non-Amino Acidic Ligands of DDAH-1 80
Holo-and apocystalysin from Treponema denticola: two different conformations 79
The chaperone role of the pyridoxal 5′-phosphate and its implications for rare diseases involving B6-dependent enzymes 79
Identification of Human Alanine-Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1 77
A quinonoid is an intermediate of oxidative deamination reaction catalyzed by Dopa decarboxylase 77
Harnessing inter-kingdom metabolic disparities at the human-fungal interface for novel therapeutic approaches 75
Construction, purification and characterization of untagged human liver alanine-glyoxylate aminotransferase expressed in Escherichia coli 75
Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase 74
Biochemical and Bioinformatic Studies of Mutations of Residues at the Monomer-Monomer Interface of Human Ornithine Aminotransferase Leading to Gyrate Atrophy of Choroid and Retina 74
An engineered folded PLP-bound monomer of Treponema denticola cystalysin reveals the effect of the dimeric structure on the catalytic properties of the enzyme 74
A comprehensive picture of the mutations associated with aromatic amino acid decarboxylase deficiency: from molecular mechanisms to therapy implications 73
R180T variant of δ-ornithine aminotransferase associated with gyrate atrophy: biochemical, computational, X-ray and NMR studies provide insight into its catalytic features 73
Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis 71
Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis 70
Use of polymer conjugates for the intraperoxisomal delivery of engineered human alanine:glyoxylate aminotransferase as a protein therapy for primary hyperoxaluria type I 70
Commensal fungi and oxalate degradation: is there a link? 69
Treponema denticola cystalysin catalyzes beta-desulfination of L-cysteine sulfinic acid and beta-decarboxylation of L-aspartate and oxalacetate 69
Gly161 mutations associated with Primary Hyperoxaluria Type I induce the cytosolic aggregation and the intracellular degradation of the apo-form of alanine:glyoxylate aminotransferase 69
Molecular insight into the synergism between the minor allele of human liver peroxisomal alanine: Glyoxylate aminotransferase and the F152I mutation 68
Molecular and cellular basis of ornithine δ-aminotransferase deficiency caused by the V332M mutation associated with gyrate atrophy of the choroid and retina 68
Treponema denticola cystalysin exhibits a significant alanine racemase activity accompanied by transamination: mechanistic implications 68
Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications 67
The N-terminal extension is essential for the formation of the active dimeric structure of liver peroxisomal alanine:glyoxylate aminotransferase 66
Editorial: The role of cofactors in protein stability and homeostasis: Focus on human metabolism 65
Targeting Cystalysin, a Virulence Factor of Treponema denticola-Supported Periodontitis 65
Biochemical and computational approaches to improve the clinical treatment of Dopa decarboxylase-related diseases: an overview 65
Characterization of C-S Lyase from C. diphtheriae: A Possible Target for New Antimicrobial Drugs 65
Effects of interface mutations on the dimerization of alanine glyoxylate aminotransferase and implications in the mistargeting of the pathogenic variants F152I and I244T 64
Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition 64
Gain-of-function mutant p53 enhances mitochondrial ROS through the inhibition of PGC-1α/UCP2 axis in cancer cells 64
Spectroscopic and kinetic analyses reveal the pyridoxal 5'-phosphate binding mode and the catalytic features of Treponema denticola cystalysin 63
S-glutathionylation exerts opposing roles in the regulation of STAT1 and STAT3 signaling in reactive microglia 61
Intracellular ascorbic acid enhances the DNA single-strand and toxicity induced by peroxynitrite in U937 cells 61
A mini-review on the international gyrate atrophy symposium 2023: More than meets the eye. Focus on outstanding research questions 60
Rapid profiling of disease alleles using a tunable reporter of protein misfolding 60
Quercetin prevents glutathione depletion induced by dehydroascorbic acid in rabbit red blood cells 60
Primary hyperoxaluria in Italy: the past 30 years and the near future of a (not so) rare disease 59
Pyridoxal 5’-Phosphate Enzymes as Targets for Therapeutic Agents 59
Treatment options in primary hyperoxaluria Type I 59
Molecular defects of the glycine 41 variants of alanine glyoxylate aminotransferase associated with primary hyperoxaluria type I 59
A molecular journey on the pathogenesis of primary hyperoxaluria 58
Molecular insights into primary hyperoxaluria Type I pathogenesis. 58
S-Glutathionylation at Cys328 and Cys542 Impairs STAT3 Phosphorylation 55
Extending diagnostic practices in gyrate atrophy: Enzymatic characterization and the development of an in vitro pyridoxine responsiveness assay 54
Tat-mediated delivery of human alanine:glyoxylate aminotransferase in a cellular model of Primary Hyperoxaluria Type I 54
Evolutionary divergent suppressor mutations in conformational diseases 54
Site-directed mutagenesis provides insight into racemization of alanine catlayzed by "Treponema denticola" cystalysin 53
Natural and unnatural compounds rescue folding defects of human alanine:glyoxylate aminotransferase leading to Primary Hyperoxaluria Type I 53
Deficit of human ornithine aminotransferase in gyrate atrophy: Molecular, cellular, and clinical aspects 53
Oligomeric State and Thermal Stability of Apo- and Holo- Human Ornithine δ-Aminotransferase 53
PLP-Dependent Enzymes 52
Probing the role of Tyr 64 of Treponema denticola cystalysin by site-directed mutagenesis and kinetic studies 52
Molecular insights into the pathogenicity of variants associated with the aromatic amino acid decarboxylase deficiency. 52
Kidney Fibrosis and Oxidative Stress: From Molecular Pathways to New Pharmacological Opportunities 51
Lysine 238 is an essential residue for alfa, beta- elimination catalyzed by "Treponema denticola" cystalysin 51
Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases. 51
Folding pathway of the pyridoxal 5'-phosphate C-S lyase MalY from Escherichia coli 51
Human wild-type alanine:glyoxylate aminotransferase and its naturally occurring G82E variant: functional properties and physiological implications 50
Molecular and biochemical methods to assess the biological impact of Quantum Dots 50
S81 L and G170R mutations causing Primary Hyperoxaluria Type I in homozygosis and heterozygosis: an example of positive interallelic complementation. 50
Human liver peroxisomal alanine:glyoxylate aminotransferase: Different stability under chemical stress of the major allele, the minor allele, and its pathogenic G170R variant. 49
Opportunities in Primary and Enteric Hyperoxaluria at the Cross-Roads Between the Clinic and Laboratory 49
Totale 7.700
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Categoria #
all - tutte 42.406
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 42.406
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022540 0 0 7 4 14 2 15 244 24 30 93 107
2022/20231.180 89 251 10 87 81 82 1 48 491 1 36 3
2023/2024425 33 45 18 7 21 0 57 1 22 24 88 109
2024/20251.590 14 119 47 68 182 132 76 117 300 94 290 151
2025/20263.579 249 254 240 477 428 270 625 167 307 284 155 123
2026/2027289 88 117 84 0 0 0 0 0 0 0 0 0
Totale 8.198