IRIS - Res&Arch Institutional Research Information System - Research & Archive

Cellini, Barbara
 Distribuzione geografica
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Continente #
NA - Nord America 2.023
AS - Asia 1.772
EU - Europa 1.512
SA - Sud America 472
AF - Africa 31
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 1
Totale 5.816
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Nazione #
US - Stati Uniti d'America 1.973
SG - Singapore 917
IE - Irlanda 431
BR - Brasile 402
IT - Italia 325
HK - Hong Kong 258
CN - Cina 256
RU - Federazione Russa 215
VN - Vietnam 174
FI - Finlandia 114
DE - Germania 112
GB - Regno Unito 52
KR - Corea 48
RO - Romania 40
AR - Argentina 33
SE - Svezia 33
AT - Austria 32
UA - Ucraina 32
CA - Canada 29
IN - India 24
PL - Polonia 21
FR - Francia 19
NL - Olanda 19
ES - Italia 17
TR - Turchia 17
BD - Bangladesh 14
CH - Svizzera 14
MX - Messico 14
UZ - Uzbekistan 11
EC - Ecuador 10
JP - Giappone 10
BE - Belgio 8
CO - Colombia 8
ID - Indonesia 8
ZA - Sudafrica 8
GR - Grecia 6
LB - Libano 6
MA - Marocco 6
CL - Cile 5
VE - Venezuela 5
CZ - Repubblica Ceca 4
EG - Egitto 4
EU - Europa 4
LT - Lituania 4
PY - Paraguay 4
SA - Arabia Saudita 4
IQ - Iraq 3
KE - Kenya 3
TN - Tunisia 3
AE - Emirati Arabi Uniti 2
AL - Albania 2
BG - Bulgaria 2
BO - Bolivia 2
EE - Estonia 2
GE - Georgia 2
JO - Giordania 2
KZ - Kazakistan 2
LV - Lettonia 2
MY - Malesia 2
NP - Nepal 2
OM - Oman 2
PE - Perù 2
PK - Pakistan 2
AO - Angola 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BN - Brunei Darussalam 1
BW - Botswana 1
BY - Bielorussia 1
CG - Congo 1
CI - Costa d'Avorio 1
DZ - Algeria 1
IS - Islanda 1
JM - Giamaica 1
KN - Saint Kitts e Nevis 1
LC - Santa Lucia 1
LU - Lussemburgo 1
MD - Moldavia 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
PH - Filippine 1
PR - Porto Rico 1
QA - Qatar 1
SC - Seychelles 1
SI - Slovenia 1
SO - Somalia 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
TH - Thailandia 1
TT - Trinidad e Tobago 1
UY - Uruguay 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 5.816
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Città #
Singapore 624
Dublin 428
Chandler 285
Hong Kong 258
San Mateo 161
Boardman 120
Santa Clara 118
Perugia 115
Ashburn 105
Altamura 87
Medford 87
Princeton 87
Lawrence 83
Andover 72
Munich 60
Moscow 54
Beijing 53
Ho Chi Minh City 52
Seoul 48
Los Angeles 45
Wilmington 45
Hanoi 39
Bucharest 33
New York 32
São Paulo 32
Ann Arbor 29
The Dalles 28
San Paolo di Civitate 26
Turku 25
Dong Ket 24
Helsinki 23
Saint Petersburg 22
Piscataway 19
Rio de Janeiro 18
Warsaw 16
Brooklyn 15
Stockholm 15
Vienna 15
Denver 14
Nuremberg 14
Rome 14
Belo Horizonte 13
Chicago 13
Frankfurt am Main 12
Boston 11
Chennai 11
Norwalk 11
Dallas 10
Montreal 10
Tokyo 10
Vicenza 10
Amsterdam 9
Des Moines 9
Curitiba 8
Falls Church 8
Hefei 8
London 8
Poplar 8
Tashkent 8
Ankara 7
Birmingham 7
Brasília 7
Brussels 7
Campinas 7
Columbus 7
Guangzhou 7
Johannesburg 7
Mexico City 7
Orem 7
Phoenix 7
Redmond 7
Kocaeli 6
Novosibirsk 6
Shanghai 6
Timisoara 6
Assisi 5
Atlanta 5
Da Nang 5
Haiphong 5
Lappeenranta 5
Manchester 5
Redwood City 5
Salvador 5
Secaucus 5
Sorocaba 5
Toronto 5
Betim 4
Cabo Frio 4
Charlotte 4
Falkenstein 4
Guayaquil 4
Houston 4
Miami 4
Milan 4
Mumbai 4
Quito 4
Santo André 4
Santos 4
São Carlos 4
Teresina 4
Totale 3.836
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Nome #
Amniotic fluid stem cell-derived extracellular vesicles are independent metabolic units capable of modulating inflammasome activation in THP-1 cells 98
Cyclo(His-Pro) inhibits NLRP3 inflammasome cascade in ALS microglial cells 95
Crosstalk between long-term sublethal oxidative stress and detrimental inflammation as potential drivers for age-related retinal degeneration 94
Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy 94
The IL-17F/IL-17RC Axis Promotes Respiratory Allergy in the Proximal Airways 90
Astrocytes regulate the expression of Insulin-Like Growth Factor 1 Receptor (IGF1-R) in primary cortical neurons during in vitro senescence 88
Selectively targeting key inflammatory pathways in cystic fibrosis 88
Cardiolipin-mediated temporal response to hydroquinone toxicity in human retinal pigmented epithelial cell line 87
Potential influence of cyclo(His-pro) on proteostasis: Impact on neurodegenerative diseases 87
Molecular basis of primary hyperoxaluria: clues to innovative treatments 83
Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: Implications for Primary Hyperoxaluria type 1 82
Tryptophan Co-Metabolism at the Host-Pathogen Interface 81
Biochemical and cellular effects of a novel missense mutation of the AGXT gene associated with Primary Hyperoxaluria Type 1 79
Folding Defects Leading to Primary Hyperoxaluria 79
Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study 78
Biochemical Characterization of Aspergillus fumigatus AroH, a Putative Aromatic Amino Acid Aminotransferase 78
Identification by virtual screening and in vitro testing of human DOPA decarboxylase inhibitors. 76
Allele-specific Characterization of Alanine: Glyoxylate Aminotransferase Variants Associated with Primary Hyperoxaluria 75
Crystal structure of Aspergillus fumigatus AroH, an aromatic amino acid aminotransferase 75
Biochemical properties and oxalate-degrading activity of oxalate decarboxylase from bacillus subtilis at neutral pH 74
Molecular and Cellular Studies Reveal Folding Defects of Human Ornithine Aminotransferase Variants Associated With Gyrate Atrophy of the Choroid and Retina 73
Correlation between the molecular effects of mutations at the dimer interface of alanine–glyoxylate aminotransferase leading to primary hyperoxaluria type I and the cellular response to vitamin B6 71
Pyridoxamine and pyridoxal are more effective than pyridoxine in rescuing folding-defective variants of human alanine:glyoxylate aminotransferase causing primary hyperoxaluria type I. 70
Biochemical analyses are instrumental in identifying the impact of mutations on holo and/or apo-forms and on the region(s) of alanine:glyoxylate aminotransferase variants associated with Primary Hyperoxaluria Type I. 70
Pyridoxal 5′-phosphate-dependent enzymes at the crossroads of host–microbe tryptophan metabolism 70
Role of misfolding in rare enzymatic deficits and use of pharmacological chaperones as therapeutic approach 70
Misfolding caused by the pathogenic mutation G47R on the minor allele of alanine:glyoxylate aminotransferase and chaperoning activity of pyridoxine 69
Caenorhabditis elegans AGXT-1 is a mitochondrial and temperature-adapted ortholog of peroxisomal human AGT1: New insights into between-species divergence in glyoxylate metabolism 69
The Chaperoning Activity of Amino-oxyacetic Acid on Folding-Defective Variants of Human Alanine:Glyoxylate Aminotransferase Causing Primary Hyperoxaluria Type I 68
A quinonoid is an intermediate of oxidative deamination reaction catalyzed by Dopa decarboxylase 68
A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase 68
The chaperone role of the pyridoxal 5′-phosphate and its implications for rare diseases involving B6-dependent enzymes 67
Electrostatic interactions drive native-like aggregation of human alanine:glyoxylate aminostransferase 67
Dimerization drives proper folding of human alanine:Glyoxylate aminotransferase but is dispensable for peroxisomal targeting 67
Construction, purification and characterization of untagged human liver alanine-glyoxylate aminotransferase expressed in Escherichia coli 66
Liver-directed gene therapy for ornithine aminotransferase deficiency 64
Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis 64
Identification of Human Alanine-Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1 60
A novel pathway for metabolism of the cardiovascular risk factor homoarginine by alanine:glyoxylate aminotransferase 2 58
Gly161 mutations associated with Primary Hyperoxaluria Type I induce the cytosolic aggregation and the intracellular degradation of the apo-form of alanine:glyoxylate aminotransferase 57
Molecular Dynamics-Ensemble Docking and Biophysical Studies for Structure-Based Identification of Non-Amino Acidic Ligands of DDAH-1 56
R180T variant of δ-ornithine aminotransferase associated with gyrate atrophy: biochemical, computational, X-ray and NMR studies provide insight into its catalytic features 56
Biochemical and Bioinformatic Studies of Mutations of Residues at the Monomer-Monomer Interface of Human Ornithine Aminotransferase Leading to Gyrate Atrophy of Choroid and Retina 55
CRISPR/Cas9-mediated knock-out of AGXT1 in HepG2 cells as a new in vitro model of Primary Hyperoxaluria Type 1 55
Targeting Cystalysin, a Virulence Factor of Treponema denticola-Supported Periodontitis 55
Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses 55
Molecular insight into the synergism between the minor allele of human liver peroxisomal alanine: Glyoxylate aminotransferase and the F152I mutation 54
Biochemical and computational approaches to improve the clinical treatment of Dopa decarboxylase-related diseases: an overview 54
Molecular and cellular basis of ornithine δ-aminotransferase deficiency caused by the V332M mutation associated with gyrate atrophy of the choroid and retina 54
Use of polymer conjugates for the intraperoxisomal delivery of engineered human alanine:glyoxylate aminotransferase as a protein therapy for primary hyperoxaluria type I 54
Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications 53
A comprehensive picture of the mutations associated with aromatic amino acid decarboxylase deficiency: from molecular mechanisms to therapy implications 53
Treponema denticola cystalysin catalyzes beta-desulfination of L-cysteine sulfinic acid and beta-decarboxylation of L-aspartate and oxalacetate 53
Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase 52
The ILE56 mutation on different genetic backgrounds of alanine:glyoxylate aminotransferase: Clinical features and biochemical characterization 52
Treponema denticola cystalysin exhibits a significant alanine racemase activity accompanied by transamination: mechanistic implications 52
Characterization of C-S Lyase from C. diphtheriae: A Possible Target for New Antimicrobial Drugs 51
Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition 51
Gain-of-function mutant p53 enhances mitochondrial ROS through the inhibition of PGC-1α/UCP2 axis in cancer cells 51
Commensal fungi and oxalate degradation: is there a link? 50
An engineered folded PLP-bound monomer of Treponema denticola cystalysin reveals the effect of the dimeric structure on the catalytic properties of the enzyme 50
Treatment options in primary hyperoxaluria Type I 50
Spectroscopic and kinetic analyses reveal the pyridoxal 5'-phosphate binding mode and the catalytic features of Treponema denticola cystalysin 49
Molecular defects of the glycine 41 variants of alanine glyoxylate aminotransferase associated with primary hyperoxaluria type I 49
Editorial: The role of cofactors in protein stability and homeostasis: Focus on human metabolism 48
The N-terminal extension is essential for the formation of the active dimeric structure of liver peroxisomal alanine:glyoxylate aminotransferase 48
Intracellular ascorbic acid enhances the DNA single-strand and toxicity induced by peroxynitrite in U937 cells 48
Effects of interface mutations on the dimerization of alanine glyoxylate aminotransferase and implications in the mistargeting of the pathogenic variants F152I and I244T 47
Rapid profiling of disease alleles using a tunable reporter of protein misfolding 47
Natural and unnatural compounds rescue folding defects of human alanine:glyoxylate aminotransferase leading to Primary Hyperoxaluria Type I 47
Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis 47
S-Glutathionylation at Cys328 and Cys542 Impairs STAT3 Phosphorylation 46
Pyridoxal 5’-Phosphate Enzymes as Targets for Therapeutic Agents 45
S-glutathionylation exerts opposing roles in the regulation of STAT1 and STAT3 signaling in reactive microglia 45
Deficit of human ornithine aminotransferase in gyrate atrophy: Molecular, cellular, and clinical aspects 45
Primary hyperoxaluria in Italy: the past 30 years and the near future of a (not so) rare disease 44
PLP-Dependent Enzymes 44
Oligomeric State and Thermal Stability of Apo- and Holo- Human Ornithine δ-Aminotransferase 44
Quercetin prevents glutathione depletion induced by dehydroascorbic acid in rabbit red blood cells 43
Molecular insights into the pathogenicity of variants associated with the aromatic amino acid decarboxylase deficiency. 43
Biochemical Studies on Human Ornithine Aminotransferase Support a Cell-Based Enzyme Replacement Therapy in the Gyrate Atrophy of the Choroid and Retina 42
Holo-and apocystalysin from Treponema denticola: two different conformations 42
Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases. 42
Liver peroxisomal alanine:glyoxylate aminotransferase and the effects of mutations associated with Primary Hyperoxaluria Type I: An overview. 42
A molecular journey on the pathogenesis of primary hyperoxaluria 41
A mini-review on the international gyrate atrophy symposium 2023: More than meets the eye. Focus on outstanding research questions 41
Lysine 238 is an essential residue for alfa, beta- elimination catalyzed by "Treponema denticola" cystalysin 41
S81 L and G170R mutations causing Primary Hyperoxaluria Type I in homozygosis and heterozygosis: an example of positive interallelic complementation. 41
Extending diagnostic practices in gyrate atrophy: Enzymatic characterization and the development of an in vitro pyridoxine responsiveness assay 40
Site-directed mutagenesis provides insight into racemization of alanine catlayzed by "Treponema denticola" cystalysin 40
Molecular and biochemical methods to assess the biological impact of Quantum Dots 40
Human wild-type alanine:glyoxylate aminotransferase and its naturally occurring G82E variant: functional properties and physiological implications 39
Folding pathway of the pyridoxal 5'-phosphate C-S lyase MalY from Escherichia coli 39
Evolutionary divergent suppressor mutations in conformational diseases 39
Harnessing inter-kingdom metabolic disparities at the human-fungal interface for novel therapeutic approaches 38
S250F variant associated with aromatic amino acid decarboxylase deficiency: molecular defects and intracellular rescue by pyridoxine 38
Human liver peroxisomal alanine:glyoxylate aminotransferase: Characterization of the two allelic forms and their pathogenic variants. 38
Probing the role of Tyr 64 of Treponema denticola cystalysin by site-directed mutagenesis and kinetic studies 38
Tat-mediated delivery of human alanine:glyoxylate aminotransferase in a cellular model of Primary Hyperoxaluria Type I 37
Human liver peroxisomal alanine:glyoxylate aminotransferase: Different stability under chemical stress of the major allele, the minor allele, and its pathogenic G170R variant. 37
Totale 5.807
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Categoria #
all - tutte 33.335
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 33.335
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202159 0 0 0 0 0 1 7 2 13 7 5 24
2021/2022639 2 97 7 4 14 2 15 244 24 30 93 107
2022/20231.180 89 251 10 87 81 82 1 48 491 1 36 3
2023/2024425 33 45 18 7 21 0 57 1 22 24 88 109
2024/20251.590 14 119 47 68 182 132 76 117 300 94 290 151
2025/20261.745 249 254 240 477 428 97 0 0 0 0 0 0
Totale 6.075