IRIS - Res&Arch Institutional Research Information System - Research & Archive

MANFRONI, GIUSEPPE
 Distribuzione geografica
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Continente #
AS - Asia 4.590
NA - Nord America 3.597
EU - Europa 2.661
SA - Sud America 313
AF - Africa 39
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 4
Totale 11.214
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Nazione #
US - Stati Uniti d'America 3.539
CN - Cina 2.446
SG - Singapore 1.125
IT - Italia 690
IE - Irlanda 442
HK - Hong Kong 402
VN - Vietnam 337
RU - Federazione Russa 307
SE - Svezia 294
BR - Brasile 271
UA - Ucraina 270
DE - Germania 175
FI - Finlandia 130
GB - Regno Unito 85
KR - Corea 82
BE - Belgio 64
FR - Francia 40
IN - India 36
JP - Giappone 36
PL - Polonia 36
CA - Canada 32
TR - Turchia 26
ES - Italia 24
MX - Messico 24
NL - Olanda 22
CH - Svizzera 17
AR - Argentina 16
AT - Austria 16
BD - Bangladesh 14
RO - Romania 14
CZ - Repubblica Ceca 13
ZA - Sudafrica 13
IQ - Iraq 12
UZ - Uzbekistan 12
ID - Indonesia 10
PK - Pakistan 9
AU - Australia 8
EC - Ecuador 8
EG - Egitto 7
LB - Libano 7
MA - Marocco 7
IR - Iran 6
CI - Costa d'Avorio 5
LT - Lituania 5
CL - Cile 4
PE - Perù 4
AL - Albania 3
CO - Colombia 3
DK - Danimarca 3
EU - Europa 3
IL - Israele 3
SA - Arabia Saudita 3
UY - Uruguay 3
AE - Emirati Arabi Uniti 2
AZ - Azerbaigian 2
BG - Bulgaria 2
BO - Bolivia 2
DZ - Algeria 2
JO - Giordania 2
KE - Kenya 2
KZ - Kazakistan 2
NP - Nepal 2
NZ - Nuova Zelanda 2
PH - Filippine 2
PS - Palestinian Territory 2
SK - Slovacchia (Repubblica Slovacca) 2
TW - Taiwan 2
AM - Armenia 1
CM - Camerun 1
DM - Dominica 1
EE - Estonia 1
GE - Georgia 1
HN - Honduras 1
HU - Ungheria 1
KW - Kuwait 1
LK - Sri Lanka 1
LV - Lettonia 1
LY - Libia 1
MD - Moldavia 1
MO - Macao, regione amministrativa speciale della Cina 1
MY - Malesia 1
NO - Norvegia 1
OM - Oman 1
PT - Portogallo 1
PY - Paraguay 1
RS - Serbia 1
SR - Suriname 1
TH - Thailandia 1
TN - Tunisia 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 11.214
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Città #
Guangzhou 2.080
Singapore 773
Chandler 600
Dublin 442
Perugia 404
Hong Kong 394
Dong Ket 246
San Mateo 226
Ashburn 206
Boardman 164
Santa Clara 143
Jacksonville 136
Medford 103
Princeton 103
Altamura 95
Beijing 90
Ann Arbor 83
Seoul 80
Wilmington 80
Los Angeles 70
Lawrence 66
Moscow 66
Brussels 64
Fremont 54
Andover 53
New York 52
Munich 50
Ho Chi Minh City 38
São Paulo 37
The Dalles 36
Piscataway 32
Redmond 32
Saint Petersburg 31
Tokyo 30
Turku 29
Dallas 28
Warsaw 28
Dearborn 27
Rome 25
Spoleto 25
Des Moines 24
Orem 22
Atlanta 21
Redwood City 21
Brooklyn 20
West Jordan 20
Falls Church 19
Norwalk 19
Denver 18
Hanoi 18
Helsinki 17
Hefei 16
Phoenix 16
Chicago 15
Columbus 15
Montreal 15
Seattle 15
Poplar 13
Chennai 12
Stockholm 12
Houston 11
Nuremberg 11
San Diego 11
San Giustino 11
Ankara 10
Izmir 10
San Francisco 10
Johannesburg 9
Lappeenranta 9
Porto Alegre 9
Rio de Janeiro 9
San Paolo di Civitate 9
Toronto 9
Woodbridge 9
Boston 8
Charlotte 8
Amsterdam 7
Bucharest 7
Council Bluffs 7
Den Haag 7
Jakarta 7
Manchester 7
Melbourne 7
Olomouc 7
Querétaro 7
San Jose 7
Vienna 7
Zhengzhou 7
Hanover 6
London 6
Mexico City 6
Nanjing 6
Newark 6
Abidjan 5
Belo Horizonte 5
Brasília 5
Curitiba 5
Da Nang 5
Hangzhou 5
Mumbai 5
Totale 7.971
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Nome #
Structural investigation of Small Molecules Targeting Influenza A Virus Polymerase 2.124
1,4-Benzothiazine ATP-Sensitive Potassium Channel Openers: Modifications at the C-2 and C-6 Positions 302
1,2,4-triazolo[1,5-α]pyrimidines as a novel class of inhibitors of the HIV-1 reverse transcriptase-αssociated ribonuclease h activity 290
Sintesi di nuovi inibitori della pompa di efflusso NorA dello S. aureus: dalle 3-fenil-1,4-benzotiazine alle 2-fenilchinossaline 154
Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase 137
Derivati 2-fenilchinolonici come inibitori della pompa di efflusso NorA dello Staphylococcus aureus ciprofloxacin resistente 127
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors 122
A Broad Anti-influenza Hybrid Small Molecule that Potently Disrupts the Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits Interaction 113
New Insights on KCa3.1 Channel Modulation 112
2-phenylquinolones as HIV-1 Tat/TAR interaction inhibitors 110
Structure-activity relationship study on anti-HIV 6-desfluoroquinolones. 110
2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction 110
New anti-ovarian cancer quinolone derivatives acting by modulating microRNA processing machinery 109
A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors 108
A New Promising Class of pyrazolobenzothiazine inhibitors of S. aureus NorA Efflux Pump 106
Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation 106
Syhtesis and Biological Evaluation of 2-Phenylquinolones Targeted at Tat/TAR Recognition 105
Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase 105
Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development 105
6-Desfluoroquinolones as promising HIV transcription inhibitors 104
C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors 104
Broad-Spectrum Flavivirus Inhibitors: a Medicinal Chemistry Point of View 104
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors 103
A New Derivative with Ultra-Potent Anti-HIV Activity 99
A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates 99
A Comprehensive Structural Overview of p38 Mitogen-Activated Protein Kinase in Complex with ATP-Site and Non-ATP-Site Binders 99
Targeting CDKs to inhibit the HIV-1 TAT-mediated transcription 98
Advantageous Use of Ionic Liquids for the Synthesis of Pharmaceutically Relevant Quinolones 98
Disegno e Sintesi di Nuovi Inibitori Allosterici della NS5B Polimerasi dell'HCV 97
Inhibition of Subgenomic Hepatitis C Virus RNA Replication by Acridone Derivatives: Identification of an NS3 Helicase Inhibitor. 96
Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents 96
Evolution of HCV NS4B Inhibitors 96
Computer-Aided Identification of Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 95
CYCLOHEPTATHIOPHENE-3-CARBOXAMIDE DERIVATIVES AS INFLUENZA A VIRUS POLYMERASE INHIBITORS 95
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B Palm Site I inhibitors case study. 95
Discovery of Novel Inhibitors of the NorA Multidrug Transporter of Staphylococcus aureus. 94
Synthesis and Characterization of 1,2,4-Triazolo[1,5-a]pyrimidine-2-carboxamide-based Compounds Targeting the PA-PB1 Interface of Influenza A Virus Polymerase. 94
Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions 93
A new quinolone derivative with ultra-potent anti-HIV activity. 92
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 91
N-Benzoyl-N-methylsulfonyl anthranilates: unexpected cyclization reaction to 4-alkoxy-2,1-benzothiazines 89
Design and synthesis of WM5 analogues as HIV-1 TAR RNA binders. 89
Synthesis of 2-(Arylamino)ethanethiols via Lewis Acid catalyzed Aminolysis of 2,2-Dimethylthiirane as Precursors of the 1,4-Benzothiazine Nucleus 88
Evolution from a natural flavones nucleus to obtain 2-(4-Propoxyphenyl)quinoline derivatives as potent inhibitors of the S. aureus NorA efflux pump. 88
Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position 87
2-Phenylquinazolinone fragment imparts anti-CDKs and anti-HIV activities 86
Co-crystal structure determination and cellular evaluation of 1,4-dihydropyrazolo[4,3-c] [1,2] benzothiazine 5,5-dioxide p38α MAPK inhibitors 86
Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors 86
New Pyrazolobenzothiazine Derivatives As Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors 86
Studies on Anti-HIV Quinolones: New Insights on the C-6 Position 84
The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors 83
Sustainable, three-component, one-pot procedure to obtain active anti-flavivirus agents 83
From Quinoline to Quinazoline-Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search 83
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 82
Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 82
Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization 82
Investigation on the effect of known potent S. aureus NorA efflux pump inhibitors on the staphylococcal biofilm formation 82
Structural Modifications of 2-phenylquinoline Inhibitors of S. aureus MDR NorA efflux pump 81
Studies of Anti-HIV Transcription Inhibitor Quinolones: Identification of Potent N1-Vinyl Derivatives 79
Structural optimization of the 2-Phenyl-4-hydroxyquinoline Class of S. aureus NorA Efflux Pump Inhibitors 79
6-Aminoquinolones targeting HCV NS5B polymerase. 79
Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues 79
A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation 77
Structure modifications of 6-aminoquinolones with potent anti-HIV activity 76
New C-6 functionalized quinoline NorA inhibitors strongly synergize with ciprofloxacin against planktonic and biofilm growing resistant Staphylococcus aureus strains 75
Structural Modifications of 2-phenylquinoline Inhibitors of S. aureus MDR NorA efflux pump 73
Cycloheptathiophene-3-carboxamide derivatives as influenza A virus polymerase inhibitors 73
Comprehensive response to usutu virus following first isolation in blood donors in the friuli venezia giulia region of italy: Development of recombinant ns1-based serology and sensitivity to antiviral drugs 73
Lipid nanoparticles for brain targeting III. Long-term stability and in vivo toxicity 72
Modulating microRNA Processing: Enoxacin, the Progenitor of a New Class of Drugs 72
Novel 1,4-Benzothiazine Derivatives as Large Conductance Ca2+-Activated Potassium Channel Openers 70
Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli 69
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity 69
Re-evolution of the 2-phenylquinolines: Ligand-Based Design, Synthesis, and Biological Evaluation of a Potent New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors to Combat Antimicrobial Resistance 68
Boosting Effect of 2-Phenylquinoline Efflux Inhibitors in Combination with Macrolides against Mycobacterium smegmatis and Mycobacterium avium 67
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor 67
Functionalized sulfonyl anthranilic acid derivatives inhibit replication of all the four dengue serotypes 66
Modifications on C6 and C7 Positions of 3-Phenylquinolone Efflux Pump Inhibitors Led to Potent and Safe Antimycobacterial Treatment Adjuvants 65
Novel N-benzyl-1,4-benzothiazine derivates as large conductance Ca2+-activated potassium channel activators 64
Searching New HCV NS5B Polymerase Inhibithors 63
Nuovi chemotipi di inibitori dell'HCV NS5B polimerasi 63
DERIVATI 2-FENIL-4-IDROSSI-CHINOLINICI COME POTENTI INBITORI DELLA POMPA D’EFFLUSSO NorA DELLO S. aureus 63
Small molecole targeting HPV E6 and E7 oncoproteins expression. 63
Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium 63
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 62
Discovery of 2‐phenylquinazolines as potent Mycobacterium avium efflux pump inhibitors able to synergize with clarithromycin against clinical isolate 61
New chemotypes to fight HCV infection: discovery of selective inhibitors of HCV replication with pyrazolobenzothiazine scaffold 60
Structure-Based Discovery of Pyrazolobenzothiazine Derivatives As Inhibitors of Hepatitis C Virus Replication 60
Effetto Inibitorio di derivati Acridonici sulla Replicazione del virus dell’epatite C (HCV). 59
Effetto inibitorio di derivati acridonici sulla replicazione del virus dell'epatite C (HCV) 59
Pyrazolo[4,3-c][1,2]benzothiazines 5,5-Dioxide: A Promising New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors 59
Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity 58
Selective anti-BVDV acridones as new potential anti-HCV agents 57
SMALL MOLECULES TARGETING HPV E6 AND E7 ONCOPROTEINS EXPRESSION 56
Structural investigation of the naphthyridone scaffold: identification of a 1,6-naphthyridone derivative with potent and selective anti-HIV activity. 55
Synthesis and anti-BVDV activity of acridones as new potential antiviral agents 55
Targeting the HIV Tat-mediated transcriptional machinery: P-TEFb complex inhibitors 54
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 53
Studies on anti-HIV Quinolones 51
TARGETING CDKs TO INHIBIT THE HIV-1 TAT-MEDIATED TRANSCRIPTION 51
Totale 10.861
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Categoria #
all - tutte 44.863
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 44.863
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021640 0 0 0 0 0 93 109 9 87 35 44 263
2021/2022991 27 154 17 63 76 12 32 267 61 32 115 135
2022/20231.780 111 312 23 162 155 172 1 100 619 14 76 35
2023/20242.850 42 114 29 16 18 22 2.263 22 71 41 93 119
2024/20251.969 23 158 73 182 202 122 234 115 336 104 282 138
2025/20262.078 268 249 196 508 595 262 0 0 0 0 0 0
Totale 11.604