IRIS - Res&Arch Institutional Research Information System - Research & Archive

MANFRONI, GIUSEPPE
 Distribuzione geografica
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Continente #
AS - Asia 4.702
NA - Nord America 3.617
EU - Europa 2.664
SA - Sud America 317
AF - Africa 40
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 4
Totale 11.354
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Nazione #
US - Stati Uniti d'America 3.559
CN - Cina 2.452
SG - Singapore 1.193
IT - Italia 690
IE - Irlanda 442
HK - Hong Kong 402
VN - Vietnam 364
RU - Federazione Russa 308
SE - Svezia 294
BR - Brasile 274
UA - Ucraina 270
DE - Germania 175
FI - Finlandia 130
GB - Regno Unito 85
KR - Corea 82
BE - Belgio 64
FR - Francia 40
IN - India 37
JP - Giappone 36
PL - Polonia 36
CA - Canada 32
TR - Turchia 26
ES - Italia 25
MX - Messico 24
NL - Olanda 22
BD - Bangladesh 18
CH - Svizzera 17
AR - Argentina 16
AT - Austria 16
RO - Romania 14
CZ - Repubblica Ceca 13
UZ - Uzbekistan 13
ZA - Sudafrica 13
IQ - Iraq 12
PK - Pakistan 11
ID - Indonesia 10
AU - Australia 8
EC - Ecuador 8
EG - Egitto 7
LB - Libano 7
MA - Marocco 7
IR - Iran 6
CI - Costa d'Avorio 5
CL - Cile 5
LT - Lituania 5
PE - Perù 4
AL - Albania 3
CO - Colombia 3
DK - Danimarca 3
EU - Europa 3
IL - Israele 3
KE - Kenya 3
OM - Oman 3
SA - Arabia Saudita 3
UY - Uruguay 3
AE - Emirati Arabi Uniti 2
AZ - Azerbaigian 2
BG - Bulgaria 2
BO - Bolivia 2
DZ - Algeria 2
JO - Giordania 2
KZ - Kazakistan 2
NP - Nepal 2
NZ - Nuova Zelanda 2
PH - Filippine 2
PS - Palestinian Territory 2
SK - Slovacchia (Repubblica Slovacca) 2
TW - Taiwan 2
AM - Armenia 1
CM - Camerun 1
DM - Dominica 1
EE - Estonia 1
GE - Georgia 1
HN - Honduras 1
HR - Croazia 1
HU - Ungheria 1
KW - Kuwait 1
LK - Sri Lanka 1
LV - Lettonia 1
LY - Libia 1
MD - Moldavia 1
MO - Macao, regione amministrativa speciale della Cina 1
MY - Malesia 1
NO - Norvegia 1
PT - Portogallo 1
PY - Paraguay 1
RS - Serbia 1
SR - Suriname 1
SY - Repubblica araba siriana 1
TH - Thailandia 1
TN - Tunisia 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 11.354
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Città #
Guangzhou 2.080
Singapore 841
Chandler 600
Dublin 442
Perugia 404
Hong Kong 394
Dong Ket 246
San Mateo 226
Ashburn 221
Boardman 164
Santa Clara 143
Jacksonville 136
Medford 103
Princeton 103
Altamura 95
Beijing 90
Ann Arbor 83
Seoul 80
Wilmington 80
Los Angeles 72
Lawrence 66
Moscow 66
Brussels 64
Fremont 54
Andover 53
New York 52
Ho Chi Minh City 51
Munich 50
São Paulo 37
The Dalles 36
Piscataway 32
Redmond 32
Saint Petersburg 31
Tokyo 30
Turku 29
Dallas 28
Warsaw 28
Dearborn 27
Rome 25
Spoleto 25
Des Moines 24
Hanoi 23
Atlanta 22
Orem 22
Redwood City 21
Brooklyn 20
West Jordan 20
Falls Church 19
Norwalk 19
Denver 18
Helsinki 17
Hefei 16
Phoenix 16
Chicago 15
Columbus 15
Montreal 15
Seattle 15
Poplar 13
Chennai 12
Stockholm 12
Houston 11
Nuremberg 11
San Diego 11
San Giustino 11
Ankara 10
Izmir 10
San Francisco 10
Johannesburg 9
Lappeenranta 9
Porto Alegre 9
Rio de Janeiro 9
San Jose 9
San Paolo di Civitate 9
Toronto 9
Woodbridge 9
Boston 8
Charlotte 8
Amsterdam 7
Bucharest 7
Council Bluffs 7
Da Nang 7
Den Haag 7
Jakarta 7
Manchester 7
Melbourne 7
Olomouc 7
Querétaro 7
Vienna 7
Zhengzhou 7
Brasília 6
Dhaka 6
Hanover 6
London 6
Mexico City 6
Nanjing 6
Newark 6
Abidjan 5
Belo Horizonte 5
Curitiba 5
Haiphong 5
Totale 8.081
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Nome #
Structural investigation of Small Molecules Targeting Influenza A Virus Polymerase 2.124
1,4-Benzothiazine ATP-Sensitive Potassium Channel Openers: Modifications at the C-2 and C-6 Positions 302
1,2,4-triazolo[1,5-α]pyrimidines as a novel class of inhibitors of the HIV-1 reverse transcriptase-αssociated ribonuclease h activity 291
Sintesi di nuovi inibitori della pompa di efflusso NorA dello S. aureus: dalle 3-fenil-1,4-benzotiazine alle 2-fenilchinossaline 154
Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase 139
Derivati 2-fenilchinolonici come inibitori della pompa di efflusso NorA dello Staphylococcus aureus ciprofloxacin resistente 128
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors 123
2-phenylquinolones as HIV-1 Tat/TAR interaction inhibitors 114
New Insights on KCa3.1 Channel Modulation 114
A Broad Anti-influenza Hybrid Small Molecule that Potently Disrupts the Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits Interaction 113
New anti-ovarian cancer quinolone derivatives acting by modulating microRNA processing machinery 112
Structure-activity relationship study on anti-HIV 6-desfluoroquinolones. 111
2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction 111
Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development 110
A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors 109
Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase 108
Syhtesis and Biological Evaluation of 2-Phenylquinolones Targeted at Tat/TAR Recognition 106
6-Desfluoroquinolones as promising HIV transcription inhibitors 106
A New Promising Class of pyrazolobenzothiazine inhibitors of S. aureus NorA Efflux Pump 106
C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors 106
Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation 106
Broad-Spectrum Flavivirus Inhibitors: a Medicinal Chemistry Point of View 106
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors 105
A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates 101
A Comprehensive Structural Overview of p38 Mitogen-Activated Protein Kinase in Complex with ATP-Site and Non-ATP-Site Binders 100
A New Derivative with Ultra-Potent Anti-HIV Activity 99
Targeting CDKs to inhibit the HIV-1 TAT-mediated transcription 99
Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents 99
Advantageous Use of Ionic Liquids for the Synthesis of Pharmaceutically Relevant Quinolones 99
Disegno e Sintesi di Nuovi Inibitori Allosterici della NS5B Polimerasi dell'HCV 98
Computer-Aided Identification of Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 98
Inhibition of Subgenomic Hepatitis C Virus RNA Replication by Acridone Derivatives: Identification of an NS3 Helicase Inhibitor. 97
Evolution of HCV NS4B Inhibitors 97
Discovery of Novel Inhibitors of the NorA Multidrug Transporter of Staphylococcus aureus. 96
CYCLOHEPTATHIOPHENE-3-CARBOXAMIDE DERIVATIVES AS INFLUENZA A VIRUS POLYMERASE INHIBITORS 96
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B Palm Site I inhibitors case study. 96
Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions 95
Synthesis and Characterization of 1,2,4-Triazolo[1,5-a]pyrimidine-2-carboxamide-based Compounds Targeting the PA-PB1 Interface of Influenza A Virus Polymerase. 95
A new quinolone derivative with ultra-potent anti-HIV activity. 92
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 92
N-Benzoyl-N-methylsulfonyl anthranilates: unexpected cyclization reaction to 4-alkoxy-2,1-benzothiazines 91
Design and synthesis of WM5 analogues as HIV-1 TAR RNA binders. 91
New Pyrazolobenzothiazine Derivatives As Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors 90
Evolution from a natural flavones nucleus to obtain 2-(4-Propoxyphenyl)quinoline derivatives as potent inhibitors of the S. aureus NorA efflux pump. 89
Synthesis of 2-(Arylamino)ethanethiols via Lewis Acid catalyzed Aminolysis of 2,2-Dimethylthiirane as Precursors of the 1,4-Benzothiazine Nucleus 88
Co-crystal structure determination and cellular evaluation of 1,4-dihydropyrazolo[4,3-c] [1,2] benzothiazine 5,5-dioxide p38α MAPK inhibitors 88
Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors 88
2-Phenylquinazolinone fragment imparts anti-CDKs and anti-HIV activities 87
Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position 87
Investigation on the effect of known potent S. aureus NorA efflux pump inhibitors on the staphylococcal biofilm formation 86
From Quinoline to Quinazoline-Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search 86
Studies on Anti-HIV Quinolones: New Insights on the C-6 Position 84
Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 84
Sustainable, three-component, one-pot procedure to obtain active anti-flavivirus agents 84
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 83
The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors 83
Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization 82
Studies of Anti-HIV Transcription Inhibitor Quinolones: Identification of Potent N1-Vinyl Derivatives 81
Structural Modifications of 2-phenylquinoline Inhibitors of S. aureus MDR NorA efflux pump 81
6-Aminoquinolones targeting HCV NS5B polymerase. 81
Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues 81
A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation 80
Structural optimization of the 2-Phenyl-4-hydroxyquinoline Class of S. aureus NorA Efflux Pump Inhibitors 80
New C-6 functionalized quinoline NorA inhibitors strongly synergize with ciprofloxacin against planktonic and biofilm growing resistant Staphylococcus aureus strains 78
Structure modifications of 6-aminoquinolones with potent anti-HIV activity 77
Structural Modifications of 2-phenylquinoline Inhibitors of S. aureus MDR NorA efflux pump 74
Comprehensive response to usutu virus following first isolation in blood donors in the friuli venezia giulia region of italy: Development of recombinant ns1-based serology and sensitivity to antiviral drugs 74
Modulating microRNA Processing: Enoxacin, the Progenitor of a New Class of Drugs 74
Cycloheptathiophene-3-carboxamide derivatives as influenza A virus polymerase inhibitors 73
Lipid nanoparticles for brain targeting III. Long-term stability and in vivo toxicity 73
Novel 1,4-Benzothiazine Derivatives as Large Conductance Ca2+-Activated Potassium Channel Openers 71
Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli 70
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity 70
Boosting Effect of 2-Phenylquinoline Efflux Inhibitors in Combination with Macrolides against Mycobacterium smegmatis and Mycobacterium avium 69
Re-evolution of the 2-phenylquinolines: Ligand-Based Design, Synthesis, and Biological Evaluation of a Potent New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors to Combat Antimicrobial Resistance 68
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor 68
Functionalized sulfonyl anthranilic acid derivatives inhibit replication of all the four dengue serotypes 67
Modifications on C6 and C7 Positions of 3-Phenylquinolone Efflux Pump Inhibitors Led to Potent and Safe Antimycobacterial Treatment Adjuvants 67
Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium 66
Novel N-benzyl-1,4-benzothiazine derivates as large conductance Ca2+-activated potassium channel activators 65
Searching New HCV NS5B Polymerase Inhibithors 64
Nuovi chemotipi di inibitori dell'HCV NS5B polimerasi 64
Small molecole targeting HPV E6 and E7 oncoproteins expression. 64
DERIVATI 2-FENIL-4-IDROSSI-CHINOLINICI COME POTENTI INBITORI DELLA POMPA D’EFFLUSSO NorA DELLO S. aureus 63
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 63
Discovery of 2‐phenylquinazolines as potent Mycobacterium avium efflux pump inhibitors able to synergize with clarithromycin against clinical isolate 62
Effetto inibitorio di derivati acridonici sulla replicazione del virus dell'epatite C (HCV) 60
New chemotypes to fight HCV infection: discovery of selective inhibitors of HCV replication with pyrazolobenzothiazine scaffold 60
Structure-Based Discovery of Pyrazolobenzothiazine Derivatives As Inhibitors of Hepatitis C Virus Replication 60
Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity 59
Effetto Inibitorio di derivati Acridonici sulla Replicazione del virus dell’epatite C (HCV). 59
Pyrazolo[4,3-c][1,2]benzothiazines 5,5-Dioxide: A Promising New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors 59
Selective anti-BVDV acridones as new potential anti-HCV agents 58
SMALL MOLECULES TARGETING HPV E6 AND E7 ONCOPROTEINS EXPRESSION 57
Structural investigation of the naphthyridone scaffold: identification of a 1,6-naphthyridone derivative with potent and selective anti-HIV activity. 56
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 55
Synthesis and anti-BVDV activity of acridones as new potential antiviral agents 55
Targeting the HIV Tat-mediated transcriptional machinery: P-TEFb complex inhibitors 54
The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors 52
Enantioresolution, stereochemical characterization and biological activity of a chiral large-conductance calcium-activated potassium channel opener. 52
Totale 10.988
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Categoria #
all - tutte 45.368
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 45.368
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021640 0 0 0 0 0 93 109 9 87 35 44 263
2021/2022991 27 154 17 63 76 12 32 267 61 32 115 135
2022/20231.780 111 312 23 162 155 172 1 100 619 14 76 35
2023/20242.850 42 114 29 16 18 22 2.263 22 71 41 93 119
2024/20251.969 23 158 73 182 202 122 234 115 336 104 282 138
2025/20262.218 268 249 196 508 595 402 0 0 0 0 0 0
Totale 11.744