IRIS - Res&Arch Institutional Research Information System - Research & Archive

MANFRONI, GIUSEPPE
 Distribuzione geografica
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Continente #
AS - Asia 3.163
NA - Nord America 2.680
EU - Europa 1.980
AF - Africa 9
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 3
SA - Sud America 2
Totale 7.844
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Nazione #
US - Stati Uniti d'America 2.678
CN - Cina 2.202
IT - Italia 487
IE - Irlanda 440
SG - Singapore 401
SE - Svezia 281
UA - Ucraina 263
VN - Vietnam 249
HK - Hong Kong 247
DE - Germania 116
RU - Federazione Russa 91
FI - Finlandia 90
BE - Belgio 60
GB - Regno Unito 44
FR - Francia 32
CH - Svizzera 16
JP - Giappone 15
RO - Romania 14
NL - Olanda 13
CZ - Repubblica Ceca 10
KR - Corea 10
PL - Polonia 9
TR - Turchia 9
UZ - Uzbekistan 8
AU - Australia 7
AT - Austria 6
IR - Iran 6
LB - Libano 6
CI - Costa d'Avorio 5
PK - Pakistan 4
EG - Egitto 3
EU - Europa 3
IN - India 3
BG - Bulgaria 2
CA - Canada 2
DK - Danimarca 2
ES - Italia 2
BR - Brasile 1
CL - Cile 1
HU - Ungheria 1
ID - Indonesia 1
IQ - Iraq 1
PT - Portogallo 1
TH - Thailandia 1
ZA - Sudafrica 1
Totale 7.844
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Città #
Guangzhou 2.074
Chandler 600
Dublin 440
Singapore 328
Dong Ket 246
Hong Kong 240
Perugia 235
San Mateo 226
Boardman 164
Jacksonville 136
Santa Clara 125
Medford 103
Princeton 103
Altamura 95
Ann Arbor 83
Wilmington 80
Lawrence 66
Brussels 60
Fremont 54
Andover 53
Beijing 52
Redmond 32
Saint Petersburg 31
Ashburn 29
Dearborn 27
Spoleto 25
Des Moines 24
Redwood City 21
West Jordan 20
Falls Church 19
Norwalk 19
Dallas 16
Helsinki 14
Los Angeles 14
Rome 12
San Diego 11
San Giustino 11
Tokyo 10
Izmir 9
Moscow 9
San Paolo di Civitate 9
Woodbridge 9
New York 8
Seoul 8
Bucharest 7
Den Haag 7
Melbourne 7
Hanover 6
Munich 6
Seattle 6
Abidjan 5
Nanjing 5
Olomouc 5
Zhengzhou 5
Arak 4
Frankfurt Am Main 4
Lausanne 4
Philadelphia 4
Shanghai 4
Timisoara 4
Wuhan 4
Anguillara Sabazia 3
Edinburgh 3
Fairfield 3
Hanoi 3
Kunming 3
Mit Ghamr 3
Napoli 3
Simi Valley 3
Turin 3
Aachen 2
Auburn Hills 2
Campegine 2
Cerro Maggiore 2
Chengdu 2
Gujranwala 2
Hangzhou 2
Hefei 2
Houston 2
Jinan 2
Kagoya 2
Leeds 2
Mcallen 2
Milan 2
Nantong 2
Naples 2
Reading 2
Romola 2
San Jose 2
Serra 2
Silver Spring 2
Tappahannock 2
Umbertide 2
Urbino 2
Warsaw 2
West Lafayette 2
Xian 2
Absecon 1
Alameda 1
Albuquerque 1
Totale 6.121
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Nome #
Structural investigation of Small Molecules Targeting Influenza A Virus Polymerase 2.099
1,4-Benzothiazine ATP-Sensitive Potassium Channel Openers: Modifications at the C-2 and C-6 Positions 230
1,2,4-triazolo[1,5-α]pyrimidines as a novel class of inhibitors of the HIV-1 reverse transcriptase-αssociated ribonuclease h activity 196
Sintesi di nuovi inibitori della pompa di efflusso NorA dello S. aureus: dalle 3-fenil-1,4-benzotiazine alle 2-fenilchinossaline 118
Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase 94
Structure-activity relationship study on anti-HIV 6-desfluoroquinolones. 89
Syhtesis and Biological Evaluation of 2-Phenylquinolones Targeted at Tat/TAR Recognition 87
Derivati 2-fenilchinolonici come inibitori della pompa di efflusso NorA dello Staphylococcus aureus ciprofloxacin resistente 86
Targeting CDKs to inhibit the HIV-1 TAT-mediated transcription 79
2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction 78
A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors 77
A New Promising Class of pyrazolobenzothiazine inhibitors of S. aureus NorA Efflux Pump 75
Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development 75
Disegno e Sintesi di Nuovi Inibitori Allosterici della NS5B Polimerasi dell'HCV 74
Inhibition of Subgenomic Hepatitis C Virus RNA Replication by Acridone Derivatives: Identification of an NS3 Helicase Inhibitor. 74
CYCLOHEPTATHIOPHENE-3-CARBOXAMIDE DERIVATIVES AS INFLUENZA A VIRUS POLYMERASE INHIBITORS 74
Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation 74
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors 73
2-phenylquinolones as HIV-1 Tat/TAR interaction inhibitors 72
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 72
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B Palm Site I inhibitors case study. 72
6-Desfluoroquinolones as promising HIV transcription inhibitors 71
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors 71
Synthesis of 2-(Arylamino)ethanethiols via Lewis Acid catalyzed Aminolysis of 2,2-Dimethylthiirane as Precursors of the 1,4-Benzothiazine Nucleus 70
A Broad Anti-influenza Hybrid Small Molecule that Potently Disrupts the Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits Interaction 69
Studies on Anti-HIV Quinolones: New Insights on the C-6 Position 68
Advantageous Use of Ionic Liquids for the Synthesis of Pharmaceutically Relevant Quinolones 66
New Insights on KCa3.1 Channel Modulation 66
A New Derivative with Ultra-Potent Anti-HIV Activity 65
A new quinolone derivative with ultra-potent anti-HIV activity. 65
2-Phenylquinazolinone fragment imparts anti-CDKs and anti-HIV activities 65
The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors 65
Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization 64
A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates 64
Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase 64
Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents 63
Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position 63
Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors 62
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 61
Evolution from a natural flavones nucleus to obtain 2-(4-Propoxyphenyl)quinoline derivatives as potent inhibitors of the S. aureus NorA efflux pump. 60
Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions 60
C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors 59
Computer-Aided Identification of Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 58
New Pyrazolobenzothiazine Derivatives As Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors 58
Synthesis and Characterization of 1,2,4-Triazolo[1,5-a]pyrimidine-2-carboxamide-based Compounds Targeting the PA-PB1 Interface of Influenza A Virus Polymerase. 58
Discovery of Novel Inhibitors of the NorA Multidrug Transporter of Staphylococcus aureus. 57
N-Benzoyl-N-methylsulfonyl anthranilates: unexpected cyclization reaction to 4-alkoxy-2,1-benzothiazines 57
Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues 57
Structure modifications of 6-aminoquinolones with potent anti-HIV activity 55
Design and synthesis of WM5 analogues as HIV-1 TAR RNA binders. 55
Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 53
A Comprehensive Structural Overview of p38 Mitogen-Activated Protein Kinase in Complex with ATP-Site and Non-ATP-Site Binders 53
Broad-Spectrum Flavivirus Inhibitors: a Medicinal Chemistry Point of View 53
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor 51
Co-crystal structure determination and cellular evaluation of 1,4-dihydropyrazolo[4,3-c] [1,2] benzothiazine 5,5-dioxide p38α MAPK inhibitors 51
Evolution of HCV NS4B Inhibitors 51
Novel 1,4-Benzothiazine Derivatives as Large Conductance Ca2+-Activated Potassium Channel Openers 50
Structural Modifications of 2-phenylquinoline Inhibitors of S. aureus MDR NorA efflux pump 50
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity 50
6-Aminoquinolones targeting HCV NS5B polymerase. 49
Effetto Inibitorio di derivati Acridonici sulla Replicazione del virus dell’epatite C (HCV). 48
DERIVATI 2-FENIL-4-IDROSSI-CHINOLINICI COME POTENTI INBITORI DELLA POMPA D’EFFLUSSO NorA DELLO S. aureus 48
Re-evolution of the 2-phenylquinolines: Ligand-Based Design, Synthesis, and Biological Evaluation of a Potent New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors to Combat Antimicrobial Resistance 48
Investigation on the effect of known potent S. aureus NorA efflux pump inhibitors on the staphylococcal biofilm formation 48
Cycloheptathiophene-3-carboxamide derivatives as influenza A virus polymerase inhibitors 47
Structure-Based Discovery of Pyrazolobenzothiazine Derivatives As Inhibitors of Hepatitis C Virus Replication 47
Searching New HCV NS5B Polymerase Inhibithors 46
Novel N-benzyl-1,4-benzothiazine derivates as large conductance Ca2+-activated potassium channel activators 46
Studies of Anti-HIV Transcription Inhibitor Quinolones: Identification of Potent N1-Vinyl Derivatives 46
New chemotypes to fight HCV infection: discovery of selective inhibitors of HCV replication with pyrazolobenzothiazine scaffold 44
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 44
Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli 44
Structural Modifications of 2-phenylquinoline Inhibitors of S. aureus MDR NorA efflux pump 43
Pyrazolo[4,3-c][1,2]benzothiazines 5,5-Dioxide: A Promising New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors 43
Selective anti-BVDV acridones as new potential anti-HCV agents 43
Lipid nanoparticles for brain targeting III. Long-term stability and in vivo toxicity 43
Boosting Effect of 2-Phenylquinoline Efflux Inhibitors in Combination with Macrolides against Mycobacterium smegmatis and Mycobacterium avium 42
Modifications on C6 and C7 Positions of 3-Phenylquinolone Efflux Pump Inhibitors Led to Potent and Safe Antimycobacterial Treatment Adjuvants 42
New C-6 functionalized quinoline NorA inhibitors strongly synergize with ciprofloxacin against planktonic and biofilm growing resistant Staphylococcus aureus strains 41
Modulating microRNA Processing: Enoxacin, the Progenitor of a New Class of Drugs 41
Structural optimization of the 2-Phenyl-4-hydroxyquinoline Class of S. aureus NorA Efflux Pump Inhibitors 40
Discovery of the 2-phenyl-4,5,6,7-Tetrahydro-1H-indole as a novel anti-hepatitis C virus targeting scaffold 40
From Quinoline to Quinazoline-Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search 40
Tumour cell population growth inhibition and cell death induction of functionalized 6-aminoquinolone derivatives 39
Effetto inibitorio di derivati acridonici sulla replicazione del virus dell'epatite C (HCV) 38
Nuovi chemotipi di inibitori dell'HCV NS5B polimerasi 38
Structural investigation of the naphthyridone scaffold: identification of a 1,6-naphthyridone derivative with potent and selective anti-HIV activity. 38
Targeting the HIV Tat-mediated transcriptional machinery: P-TEFb complex inhibitors 38
The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors 38
Small molecole targeting HPV E6 and E7 oncoproteins expression. 38
Enantioresolution, stereochemical characterization and biological activity of a chiral large-conductance calcium-activated potassium channel opener. 38
Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium 38
STRUCTURAL INVESTIGATIONS OF THE 2-PHENYL-4- HYDROXYQUINOLINE CLASS OF S. AUREUS NORA EPIS 36
Studies on anti-HIV Quinolones 35
Structural Investigation of Cycloheptathiophene-3-carboxamide Derivatives Targeting Influenza Virus Polymerase Assembly 35
Synthesis and anti-BVDV activity of acridones as new potential antiviral agents 35
Ethyl 1,8-Naphthyridone-3-carboxylates Downregulate Human Papillomavirus-16 (HPV-16) E6 and E7 Oncogenes Expression 34
SMALL MOLECULES TARGETING HPV E6 AND E7 ONCOPROTEINS EXPRESSION 33
Sustainable, three-component, one-pot procedure to obtain active anti-flavivirus agents 31
Studies on Cycloheptathiophene-3-carboxamide Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors 30
Totale 7.921
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Categoria #
all - tutte 27.853
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 27.853
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020343 0 0 0 0 39 37 78 10 68 79 8 24
2020/20211.051 13 59 35 63 241 93 109 9 87 35 44 263
2021/2022991 27 154 17 63 76 12 32 267 61 32 115 135
2022/20231.780 111 312 23 162 155 172 1 100 619 14 76 35
2023/20242.850 42 114 29 16 18 22 2.263 22 71 41 93 119
2024/2025628 23 158 73 182 192 0 0 0 0 0 0 0
Totale 8.185