IRIS - Res&Arch Institutional Research Information System - Research & Archive

MANFRONI, GIUSEPPE
 Distribuzione geografica
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Continente #
AS - Asia 5.442
NA - Nord America 4.596
EU - Europa 3.049
SA - Sud America 417
Continente sconosciuto - Info sul continente non disponibili 405
AF - Africa 86
OC - Oceania 10
Totale 14.005
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Nazione #
US - Stati Uniti d'America 4.499
CN - Cina 2.536
SG - Singapore 1.547
IT - Italia 780
IE - Irlanda 445
HK - Hong Kong 437
VN - Vietnam 423
RU - Federazione Russa 414
BR - Brasile 314
SE - Svezia 294
UA - Ucraina 275
DE - Germania 182
FR - Francia 148
FI - Finlandia 136
GB - Regno Unito 109
KR - Corea 84
IN - India 70
BD - Bangladesh 65
BE - Belgio 64
CA - Canada 51
TR - Turchia 47
JP - Giappone 40
PL - Polonia 39
IQ - Iraq 34
MX - Messico 33
AR - Argentina 31
ES - Italia 30
NL - Olanda 27
PK - Pakistan 24
ZA - Sudafrica 23
ID - Indonesia 19
CH - Svizzera 18
PH - Filippine 18
UZ - Uzbekistan 18
AT - Austria 17
EC - Ecuador 17
RO - Romania 17
SA - Arabia Saudita 17
CO - Colombia 15
CZ - Repubblica Ceca 13
EG - Egitto 12
MA - Marocco 11
CL - Cile 10
VE - Venezuela 10
AU - Australia 8
LB - Libano 8
AL - Albania 7
ET - Etiopia 7
UY - Uruguay 7
CI - Costa d'Avorio 6
IR - Iran 6
KE - Kenya 6
PE - Perù 6
TN - Tunisia 6
JO - Giordania 5
LT - Lituania 5
LV - Lettonia 5
MY - Malesia 5
AZ - Azerbaigian 4
BG - Bulgaria 4
BO - Bolivia 4
DZ - Algeria 4
NP - Nepal 4
OM - Oman 4
AE - Emirati Arabi Uniti 3
AO - Angola 3
DK - Danimarca 3
EU - Europa 3
HR - Croazia 3
IL - Israele 3
PA - Panama 3
PS - Palestinian Territory 3
RS - Serbia 3
SY - Repubblica araba siriana 3
CR - Costa Rica 2
KZ - Kazakistan 2
LY - Libia 2
MO - Macao, regione amministrativa speciale della Cina 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
PY - Paraguay 2
SK - Slovacchia (Repubblica Slovacca) 2
SV - El Salvador 2
TH - Thailandia 2
TW - Taiwan 2
AM - Armenia 1
BY - Bielorussia 1
CM - Camerun 1
CY - Cipro 1
DM - Dominica 1
EE - Estonia 1
GA - Gabon 1
GE - Georgia 1
GR - Grecia 1
GT - Guatemala 1
HN - Honduras 1
HU - Ungheria 1
JM - Giamaica 1
KG - Kirghizistan 1
KW - Kuwait 1
Totale 13.591
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Città #
Guangzhou 2.080
Singapore 1.157
Chandler 600
San Jose 487
Dublin 445
Perugia 436
Hong Kong 425
Ashburn 291
Dong Ket 246
San Mateo 226
Santa Clara 176
Boardman 164
Jacksonville 138
Moscow 123
Beijing 116
Medford 103
Princeton 103
Lauterbourg 96
Altamura 95
Los Angeles 95
Ann Arbor 83
The Dalles 83
Wilmington 81
Seoul 80
New York 69
Ho Chi Minh City 66
Lawrence 66
Brussels 64
Fremont 56
Andover 53
Munich 50
São Paulo 43
Orem 38
Dallas 37
Piscataway 36
Hanoi 34
Rome 34
Tokyo 33
Redmond 32
Saint Petersburg 31
Council Bluffs 29
Turku 29
Warsaw 29
Dearborn 27
Des Moines 25
Spoleto 25
Atlanta 23
Helsinki 23
Montreal 23
Phoenix 23
Denver 22
Redwood City 21
Falls Church 20
West Jordan 20
Brooklyn 19
Buffalo 19
Norwalk 19
Chicago 18
Chennai 17
Hefei 16
Baghdad 15
Columbus 15
Seattle 15
Johannesburg 14
Nuremberg 13
Poplar 13
Houston 12
Stockholm 12
Dhaka 11
Izmir 11
Mexico City 11
San Diego 11
San Francisco 11
San Giustino 11
Toronto 11
Amsterdam 10
Ankara 10
Porto Alegre 10
Brasília 9
Lappeenranta 9
Mumbai 9
Philadelphia 9
Rio de Janeiro 9
San Paolo di Civitate 9
Shanghai 9
Tashkent 9
Vienna 9
Woodbridge 9
Barnet 8
Boston 8
Cairo 8
Charlotte 8
Da Nang 8
Haiphong 8
London 8
Manchester 8
Milan 8
Quito 8
Addis Ababa 7
Bucharest 7
Totale 9.518
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Nome #
Structural investigation of Small Molecules Targeting Influenza A Virus Polymerase 2.142
1,2,4-triazolo[1,5-α]pyrimidines as a novel class of inhibitors of the HIV-1 reverse transcriptase-αssociated ribonuclease h activity 337
1,4-Benzothiazine ATP-Sensitive Potassium Channel Openers: Modifications at the C-2 and C-6 Positions 320
Sintesi di nuovi inibitori della pompa di efflusso NorA dello S. aureus: dalle 3-fenil-1,4-benzotiazine alle 2-fenilchinossaline 164
Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase 156
New anti-ovarian cancer quinolone derivatives acting by modulating microRNA processing machinery 155
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors 149
New Insights on KCa3.1 Channel Modulation 146
C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors 145
A Broad Anti-influenza Hybrid Small Molecule that Potently Disrupts the Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits Interaction 142
2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction 139
Derivati 2-fenilchinolonici come inibitori della pompa di efflusso NorA dello Staphylococcus aureus ciprofloxacin resistente 138
A New Promising Class of pyrazolobenzothiazine inhibitors of S. aureus NorA Efflux Pump 136
A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates 136
From Quinoline to Quinazoline-Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search 136
2-phenylquinolones as HIV-1 Tat/TAR interaction inhibitors 135
Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development 135
Broad-Spectrum Flavivirus Inhibitors: a Medicinal Chemistry Point of View 133
Syhtesis and Biological Evaluation of 2-Phenylquinolones Targeted at Tat/TAR Recognition 130
6-Desfluoroquinolones as promising HIV transcription inhibitors 129
Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase 129
Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation 128
A Comprehensive Structural Overview of p38 Mitogen-Activated Protein Kinase in Complex with ATP-Site and Non-ATP-Site Binders 126
Structure-activity relationship study on anti-HIV 6-desfluoroquinolones. 124
A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors 124
Discovery of Novel Inhibitors of the NorA Multidrug Transporter of Staphylococcus aureus. 121
N-Benzoyl-N-methylsulfonyl anthranilates: unexpected cyclization reaction to 4-alkoxy-2,1-benzothiazines 121
Advantageous Use of Ionic Liquids for the Synthesis of Pharmaceutically Relevant Quinolones 119
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors 118
Targeting CDKs to inhibit the HIV-1 TAT-mediated transcription 117
Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents 117
Computer-Aided Identification of Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 116
Design and synthesis of WM5 analogues as HIV-1 TAR RNA binders. 115
Synthesis and Characterization of 1,2,4-Triazolo[1,5-a]pyrimidine-2-carboxamide-based Compounds Targeting the PA-PB1 Interface of Influenza A Virus Polymerase. 115
Inhibition of Subgenomic Hepatitis C Virus RNA Replication by Acridone Derivatives: Identification of an NS3 Helicase Inhibitor. 114
Disegno e Sintesi di Nuovi Inibitori Allosterici della NS5B Polimerasi dell'HCV 113
Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions 113
Evolution of HCV NS4B Inhibitors 113
Co-crystal structure determination and cellular evaluation of 1,4-dihydropyrazolo[4,3-c] [1,2] benzothiazine 5,5-dioxide p38α MAPK inhibitors 112
A New Derivative with Ultra-Potent Anti-HIV Activity 111
A new quinolone derivative with ultra-potent anti-HIV activity. 111
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B Palm Site I inhibitors case study. 111
New Pyrazolobenzothiazine Derivatives As Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors 110
A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation 109
New C-6 functionalized quinoline NorA inhibitors strongly synergize with ciprofloxacin against planktonic and biofilm growing resistant Staphylococcus aureus strains 109
2-Phenylquinazolinone fragment imparts anti-CDKs and anti-HIV activities 109
Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 108
Investigation on the effect of known potent S. aureus NorA efflux pump inhibitors on the staphylococcal biofilm formation 107
CYCLOHEPTATHIOPHENE-3-CARBOXAMIDE DERIVATIVES AS INFLUENZA A VIRUS POLYMERASE INHIBITORS 106
Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors 106
Evolution from a natural flavones nucleus to obtain 2-(4-Propoxyphenyl)quinoline derivatives as potent inhibitors of the S. aureus NorA efflux pump. 104
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 103
Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium 103
Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position 103
Synthesis of 2-(Arylamino)ethanethiols via Lewis Acid catalyzed Aminolysis of 2,2-Dimethylthiirane as Precursors of the 1,4-Benzothiazine Nucleus 102
The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors 101
Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues 101
6-Aminoquinolones targeting HCV NS5B polymerase. 99
Sustainable, three-component, one-pot procedure to obtain active anti-flavivirus agents 98
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 96
Structural optimization of the 2-Phenyl-4-hydroxyquinoline Class of S. aureus NorA Efflux Pump Inhibitors 96
Modulating microRNA Processing: Enoxacin, the Progenitor of a New Class of Drugs 96
Studies of Anti-HIV Transcription Inhibitor Quinolones: Identification of Potent N1-Vinyl Derivatives 95
Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization 94
Comprehensive response to usutu virus following first isolation in blood donors in the friuli venezia giulia region of italy: Development of recombinant ns1-based serology and sensitivity to antiviral drugs 94
Structural Modifications of 2-phenylquinoline Inhibitors of S. aureus MDR NorA efflux pump 93
Studies on Anti-HIV Quinolones: New Insights on the C-6 Position 92
Modifications on C6 and C7 Positions of 3-Phenylquinolone Efflux Pump Inhibitors Led to Potent and Safe Antimycobacterial Treatment Adjuvants 92
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor 91
Functionalized sulfonyl anthranilic acid derivatives inhibit replication of all the four dengue serotypes 89
Structure modifications of 6-aminoquinolones with potent anti-HIV activity 89
Lipid nanoparticles for brain targeting III. Long-term stability and in vivo toxicity 89
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity 89
Novel 1,4-Benzothiazine Derivatives as Large Conductance Ca2+-Activated Potassium Channel Openers 86
Structural Modifications of 2-phenylquinoline Inhibitors of S. aureus MDR NorA efflux pump 86
Cycloheptathiophene-3-carboxamide derivatives as influenza A virus polymerase inhibitors 84
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 83
Boosting Effect of 2-Phenylquinoline Efflux Inhibitors in Combination with Macrolides against Mycobacterium smegmatis and Mycobacterium avium 83
Nuovi chemotipi di inibitori dell'HCV NS5B polimerasi 81
Structural Investigation of Cycloheptathiophene-3-carboxamide Derivatives Targeting Influenza Virus Polymerase Assembly 80
Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli 80
Searching New HCV NS5B Polymerase Inhibithors 79
TARGETING CDKs TO INHIBIT THE HIV-1 TAT-MEDIATED TRANSCRIPTION 79
Re-evolution of the 2-phenylquinolines: Ligand-Based Design, Synthesis, and Biological Evaluation of a Potent New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors to Combat Antimicrobial Resistance 78
Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity 77
Novel N-benzyl-1,4-benzothiazine derivates as large conductance Ca2+-activated potassium channel activators 77
Discovery of 2‐phenylquinazolines as potent Mycobacterium avium efflux pump inhibitors able to synergize with clarithromycin against clinical isolate 75
DERIVATI 2-FENIL-4-IDROSSI-CHINOLINICI COME POTENTI INBITORI DELLA POMPA D’EFFLUSSO NorA DELLO S. aureus 75
Structural investigation of the naphthyridone scaffold: identification of a 1,6-naphthyridone derivative with potent and selective anti-HIV activity. 74
Effetto inibitorio di derivati acridonici sulla replicazione del virus dell'epatite C (HCV) 73
Small molecole targeting HPV E6 and E7 oncoproteins expression. 73
Structure-Based Discovery of Pyrazolobenzothiazine Derivatives As Inhibitors of Hepatitis C Virus Replication 73
Virucidal Activity of the Pyridobenzothiazolone Derivative HeE1-17Y against Enveloped RNA Viruses 71
Selective anti-BVDV acridones as new potential anti-HCV agents 71
New chemotypes to fight HCV infection: discovery of selective inhibitors of HCV replication with pyrazolobenzothiazine scaffold 71
NorA Efflux Pump Inhibitors: Expanding SAR Knowledge of Pyrazolo[4,3‐c][1,2]benzothiazine 5,5‐Dioxide Derivatives 70
SMALL MOLECULES TARGETING HPV E6 AND E7 ONCOPROTEINS EXPRESSION 70
Targeting the HIV Tat-mediated transcriptional machinery: P-TEFb complex inhibitors 69
The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors 69
Small Molecule Drugs Targeting Viral Polymerases 68
Totale 12.919
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Categoria #
all - tutte 54.194
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 54.194
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022964 0 154 17 63 76 12 32 267 61 32 115 135
2022/20231.780 111 312 23 162 155 172 1 100 619 14 76 35
2023/20242.850 42 114 29 16 18 22 2.263 22 71 41 93 119
2024/20251.962 23 158 73 182 202 122 233 114 335 103 280 137
2025/20264.282 265 248 191 507 589 416 742 236 480 351 186 71
2026/2027204 105 99 0 0 0 0 0 0 0 0 0 0
Totale 14.005