IRIS - Res&Arch Institutional Research Information System - Research & Archive

MANFRONI, GIUSEPPE
 Distribuzione geografica
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Continente #
AS - Asia 5.411
NA - Nord America 4.433
EU - Europa 3.030
SA - Sud America 407
AF - Africa 85
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 4
Totale 13.380
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Nazione #
US - Stati Uniti d'America 4.358
CN - Cina 2.523
SG - Singapore 1.543
IT - Italia 765
IE - Irlanda 445
HK - Hong Kong 433
VN - Vietnam 423
RU - Federazione Russa 414
BR - Brasile 311
SE - Svezia 294
UA - Ucraina 275
DE - Germania 182
FR - Francia 147
FI - Finlandia 136
GB - Regno Unito 109
KR - Corea 83
IN - India 70
BE - Belgio 64
BD - Bangladesh 60
TR - Turchia 47
JP - Giappone 40
PL - Polonia 38
CA - Canada 37
IQ - Iraq 34
MX - Messico 32
AR - Argentina 30
ES - Italia 30
NL - Olanda 26
PK - Pakistan 24
ZA - Sudafrica 23
ID - Indonesia 18
UZ - Uzbekistan 18
AT - Austria 17
CH - Svizzera 17
PH - Filippine 17
RO - Romania 17
SA - Arabia Saudita 17
EC - Ecuador 16
CZ - Repubblica Ceca 13
CO - Colombia 12
EG - Egitto 12
MA - Marocco 11
VE - Venezuela 10
CL - Cile 9
AU - Australia 8
LB - Libano 8
AL - Albania 7
ET - Etiopia 7
UY - Uruguay 7
CI - Costa d'Avorio 6
IR - Iran 6
KE - Kenya 6
TN - Tunisia 6
JO - Giordania 5
LT - Lituania 5
LV - Lettonia 5
PE - Perù 5
AZ - Azerbaigian 4
BG - Bulgaria 4
BO - Bolivia 4
DZ - Algeria 4
MY - Malesia 4
NP - Nepal 4
OM - Oman 4
AE - Emirati Arabi Uniti 3
AO - Angola 3
DK - Danimarca 3
EU - Europa 3
HR - Croazia 3
IL - Israele 3
PA - Panama 3
PS - Palestinian Territory 3
RS - Serbia 3
SY - Repubblica araba siriana 3
KZ - Kazakistan 2
LY - Libia 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
PY - Paraguay 2
SK - Slovacchia (Repubblica Slovacca) 2
TH - Thailandia 2
TW - Taiwan 2
AM - Armenia 1
BY - Bielorussia 1
CM - Camerun 1
CR - Costa Rica 1
CY - Cipro 1
DM - Dominica 1
EE - Estonia 1
GA - Gabon 1
GE - Georgia 1
GR - Grecia 1
HN - Honduras 1
HU - Ungheria 1
KG - Kirghizistan 1
KW - Kuwait 1
LK - Sri Lanka 1
MD - Moldavia 1
ME - Montenegro 1
MO - Macao, regione amministrativa speciale della Cina 1
Totale 13.373
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Città #
Guangzhou 2.080
Singapore 1.155
Chandler 600
San Jose 487
Dublin 445
Perugia 431
Hong Kong 423
Ashburn 281
Dong Ket 246
San Mateo 226
Boardman 164
Santa Clara 159
Jacksonville 137
Moscow 123
Beijing 106
Medford 103
Princeton 103
Lauterbourg 96
Altamura 95
Los Angeles 90
Ann Arbor 83
The Dalles 83
Seoul 80
Wilmington 80
Ho Chi Minh City 66
Lawrence 66
Brussels 64
New York 63
Fremont 56
Andover 53
Munich 50
São Paulo 43
Orem 38
Dallas 34
Hanoi 34
Piscataway 34
Rome 33
Tokyo 33
Redmond 32
Saint Petersburg 31
Council Bluffs 29
Turku 29
Warsaw 29
Dearborn 27
Des Moines 25
Spoleto 25
Atlanta 23
Helsinki 23
Redwood City 21
Denver 20
West Jordan 20
Brooklyn 19
Falls Church 19
Norwalk 19
Phoenix 19
Chennai 17
Chicago 16
Hefei 16
Montreal 16
Baghdad 15
Columbus 15
Seattle 15
Buffalo 14
Johannesburg 14
Nuremberg 13
Poplar 13
Stockholm 12
Dhaka 11
Houston 11
Izmir 11
San Diego 11
San Francisco 11
San Giustino 11
Ankara 10
Mexico City 10
Porto Alegre 10
Amsterdam 9
Lappeenranta 9
Mumbai 9
Rio de Janeiro 9
San Paolo di Civitate 9
Tashkent 9
Toronto 9
Vienna 9
Woodbridge 9
Barnet 8
Boston 8
Brasília 8
Cairo 8
Charlotte 8
Da Nang 8
Haiphong 8
London 8
Manchester 8
Quito 8
Shanghai 8
Addis Ababa 7
Bucharest 7
Den Haag 7
Melbourne 7
Totale 9.422
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Nome #
Structural investigation of Small Molecules Targeting Influenza A Virus Polymerase 2.140
1,2,4-triazolo[1,5-α]pyrimidines as a novel class of inhibitors of the HIV-1 reverse transcriptase-αssociated ribonuclease h activity 333
1,4-Benzothiazine ATP-Sensitive Potassium Channel Openers: Modifications at the C-2 and C-6 Positions 320
Sintesi di nuovi inibitori della pompa di efflusso NorA dello S. aureus: dalle 3-fenil-1,4-benzotiazine alle 2-fenilchinossaline 164
Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase 155
New anti-ovarian cancer quinolone derivatives acting by modulating microRNA processing machinery 153
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors 145
New Insights on KCa3.1 Channel Modulation 144
C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors 140
A Broad Anti-influenza Hybrid Small Molecule that Potently Disrupts the Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits Interaction 139
2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction 137
Derivati 2-fenilchinolonici come inibitori della pompa di efflusso NorA dello Staphylococcus aureus ciprofloxacin resistente 136
From Quinoline to Quinazoline-Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search 134
2-phenylquinolones as HIV-1 Tat/TAR interaction inhibitors 133
A New Promising Class of pyrazolobenzothiazine inhibitors of S. aureus NorA Efflux Pump 133
A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates 132
Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development 132
Broad-Spectrum Flavivirus Inhibitors: a Medicinal Chemistry Point of View 129
Syhtesis and Biological Evaluation of 2-Phenylquinolones Targeted at Tat/TAR Recognition 128
Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation 127
6-Desfluoroquinolones as promising HIV transcription inhibitors 126
Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase 126
A Comprehensive Structural Overview of p38 Mitogen-Activated Protein Kinase in Complex with ATP-Site and Non-ATP-Site Binders 124
Structure-activity relationship study on anti-HIV 6-desfluoroquinolones. 123
A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors 123
Discovery of Novel Inhibitors of the NorA Multidrug Transporter of Staphylococcus aureus. 120
N-Benzoyl-N-methylsulfonyl anthranilates: unexpected cyclization reaction to 4-alkoxy-2,1-benzothiazines 120
Advantageous Use of Ionic Liquids for the Synthesis of Pharmaceutically Relevant Quinolones 117
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors 117
Computer-Aided Identification of Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 116
Targeting CDKs to inhibit the HIV-1 TAT-mediated transcription 116
Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents 116
Synthesis and Characterization of 1,2,4-Triazolo[1,5-a]pyrimidine-2-carboxamide-based Compounds Targeting the PA-PB1 Interface of Influenza A Virus Polymerase. 115
Inhibition of Subgenomic Hepatitis C Virus RNA Replication by Acridone Derivatives: Identification of an NS3 Helicase Inhibitor. 113
Design and synthesis of WM5 analogues as HIV-1 TAR RNA binders. 113
Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions 112
A new quinolone derivative with ultra-potent anti-HIV activity. 111
Evolution of HCV NS4B Inhibitors 111
A New Derivative with Ultra-Potent Anti-HIV Activity 110
Disegno e Sintesi di Nuovi Inibitori Allosterici della NS5B Polimerasi dell'HCV 110
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B Palm Site I inhibitors case study. 110
2-Phenylquinazolinone fragment imparts anti-CDKs and anti-HIV activities 109
Co-crystal structure determination and cellular evaluation of 1,4-dihydropyrazolo[4,3-c] [1,2] benzothiazine 5,5-dioxide p38α MAPK inhibitors 109
New Pyrazolobenzothiazine Derivatives As Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors 108
A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation 105
CYCLOHEPTATHIOPHENE-3-CARBOXAMIDE DERIVATIVES AS INFLUENZA A VIRUS POLYMERASE INHIBITORS 105
Evolution from a natural flavones nucleus to obtain 2-(4-Propoxyphenyl)quinoline derivatives as potent inhibitors of the S. aureus NorA efflux pump. 104
Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 104
Investigation on the effect of known potent S. aureus NorA efflux pump inhibitors on the staphylococcal biofilm formation 104
New C-6 functionalized quinoline NorA inhibitors strongly synergize with ciprofloxacin against planktonic and biofilm growing resistant Staphylococcus aureus strains 103
Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors 103
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 102
Synthesis of 2-(Arylamino)ethanethiols via Lewis Acid catalyzed Aminolysis of 2,2-Dimethylthiirane as Precursors of the 1,4-Benzothiazine Nucleus 101
The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors 101
Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues 100
Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium 100
Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position 99
6-Aminoquinolones targeting HCV NS5B polymerase. 97
Structural optimization of the 2-Phenyl-4-hydroxyquinoline Class of S. aureus NorA Efflux Pump Inhibitors 96
Studies of Anti-HIV Transcription Inhibitor Quinolones: Identification of Potent N1-Vinyl Derivatives 95
Sustainable, three-component, one-pot procedure to obtain active anti-flavivirus agents 95
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 93
Modulating microRNA Processing: Enoxacin, the Progenitor of a New Class of Drugs 93
Structural Modifications of 2-phenylquinoline Inhibitors of S. aureus MDR NorA efflux pump 92
Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization 92
Studies on Anti-HIV Quinolones: New Insights on the C-6 Position 91
Comprehensive response to usutu virus following first isolation in blood donors in the friuli venezia giulia region of italy: Development of recombinant ns1-based serology and sensitivity to antiviral drugs 91
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor 90
Modifications on C6 and C7 Positions of 3-Phenylquinolone Efflux Pump Inhibitors Led to Potent and Safe Antimycobacterial Treatment Adjuvants 89
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity 89
Structure modifications of 6-aminoquinolones with potent anti-HIV activity 87
Lipid nanoparticles for brain targeting III. Long-term stability and in vivo toxicity 87
Functionalized sulfonyl anthranilic acid derivatives inhibit replication of all the four dengue serotypes 86
Structural Modifications of 2-phenylquinoline Inhibitors of S. aureus MDR NorA efflux pump 86
Cycloheptathiophene-3-carboxamide derivatives as influenza A virus polymerase inhibitors 84
Novel 1,4-Benzothiazine Derivatives as Large Conductance Ca2+-Activated Potassium Channel Openers 82
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 81
Boosting Effect of 2-Phenylquinoline Efflux Inhibitors in Combination with Macrolides against Mycobacterium smegmatis and Mycobacterium avium 81
Nuovi chemotipi di inibitori dell'HCV NS5B polimerasi 80
Structural Investigation of Cycloheptathiophene-3-carboxamide Derivatives Targeting Influenza Virus Polymerase Assembly 80
Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli 80
Searching New HCV NS5B Polymerase Inhibithors 78
TARGETING CDKs TO INHIBIT THE HIV-1 TAT-MEDIATED TRANSCRIPTION 78
Re-evolution of the 2-phenylquinolines: Ligand-Based Design, Synthesis, and Biological Evaluation of a Potent New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors to Combat Antimicrobial Resistance 78
Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity 77
Novel N-benzyl-1,4-benzothiazine derivates as large conductance Ca2+-activated potassium channel activators 77
DERIVATI 2-FENIL-4-IDROSSI-CHINOLINICI COME POTENTI INBITORI DELLA POMPA D’EFFLUSSO NorA DELLO S. aureus 75
Discovery of 2‐phenylquinazolines as potent Mycobacterium avium efflux pump inhibitors able to synergize with clarithromycin against clinical isolate 74
Structural investigation of the naphthyridone scaffold: identification of a 1,6-naphthyridone derivative with potent and selective anti-HIV activity. 74
Small molecole targeting HPV E6 and E7 oncoproteins expression. 73
Effetto inibitorio di derivati acridonici sulla replicazione del virus dell'epatite C (HCV) 72
New chemotypes to fight HCV infection: discovery of selective inhibitors of HCV replication with pyrazolobenzothiazine scaffold 71
Virucidal Activity of the Pyridobenzothiazolone Derivative HeE1-17Y against Enveloped RNA Viruses 70
Selective anti-BVDV acridones as new potential anti-HCV agents 70
Structure-Based Discovery of Pyrazolobenzothiazine Derivatives As Inhibitors of Hepatitis C Virus Replication 70
Targeting the HIV Tat-mediated transcriptional machinery: P-TEFb complex inhibitors 67
SMALL MOLECULES TARGETING HPV E6 AND E7 ONCOPROTEINS EXPRESSION 67
Small Molecule Drugs Targeting Viral Polymerases 66
Effetto Inibitorio di derivati Acridonici sulla Replicazione del virus dell’epatite C (HCV). 66
The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors 66
Totale 12.746
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Categoria #
all - tutte 51.330
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 51.330
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021263 0 0 0 0 0 0 0 0 0 0 0 263
2021/2022991 27 154 17 63 76 12 32 267 61 32 115 135
2022/20231.780 111 312 23 162 155 172 1 100 619 14 76 35
2023/20242.850 42 114 29 16 18 22 2.263 22 71 41 93 119
2024/20251.962 23 158 73 182 202 122 233 114 335 103 280 137
2025/20264.259 265 248 191 507 589 416 742 236 480 351 186 48
Totale 13.778