IRIS - Res&Arch Institutional Research Information System - Research & Archive

MANFRONI, GIUSEPPE
 Distribuzione geografica
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Continente #
AS - Asia 3.351
NA - Nord America 2.764
EU - Europa 2.310
SA - Sud America 50
AF - Africa 17
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 3
Totale 8.504
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Nazione #
US - Stati Uniti d'America 2.759
CN - Cina 2.213
IT - Italia 665
SG - Singapore 535
IE - Irlanda 441
SE - Svezia 283
HK - Hong Kong 269
UA - Ucraina 264
VN - Vietnam 249
RU - Federazione Russa 204
DE - Germania 124
FI - Finlandia 92
BE - Belgio 62
GB - Regno Unito 47
BR - Brasile 41
FR - Francia 32
JP - Giappone 17
NL - Olanda 17
CH - Svizzera 16
RO - Romania 14
AT - Austria 13
TR - Turchia 12
CZ - Repubblica Ceca 11
PL - Polonia 11
KR - Corea 10
UZ - Uzbekistan 9
AU - Australia 7
IR - Iran 6
LB - Libano 6
PK - Pakistan 6
CA - Canada 5
CI - Costa d'Avorio 5
EG - Egitto 5
IN - India 5
MA - Marocco 4
EU - Europa 3
IQ - Iraq 3
AL - Albania 2
BG - Bulgaria 2
CL - Cile 2
DK - Danimarca 2
EC - Ecuador 2
ES - Italia 2
NZ - Nuova Zelanda 2
PE - Perù 2
AM - Armenia 1
AR - Argentina 1
AZ - Azerbaigian 1
BO - Bolivia 1
CO - Colombia 1
DZ - Algeria 1
EE - Estonia 1
HU - Ungheria 1
ID - Indonesia 1
IL - Israele 1
JO - Giordania 1
KE - Kenya 1
KZ - Kazakistan 1
LK - Sri Lanka 1
LT - Lituania 1
LV - Lettonia 1
MO - Macao, regione amministrativa speciale della Cina 1
NP - Nepal 1
PH - Filippine 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
ZA - Sudafrica 1
Totale 8.504
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Città #
Guangzhou 2.074
Chandler 600
Dublin 441
Perugia 402
Singapore 400
Hong Kong 262
Dong Ket 246
San Mateo 226
Boardman 164
Jacksonville 136
Santa Clara 125
Medford 103
Princeton 103
Altamura 95
Ann Arbor 83
Wilmington 80
Lawrence 66
Brussels 62
Fremont 54
Andover 53
Beijing 53
Redmond 32
Saint Petersburg 31
Ashburn 30
Dearborn 27
Moscow 26
Spoleto 25
Des Moines 24
Los Angeles 22
Redwood City 21
West Jordan 20
Falls Church 19
Norwalk 19
Dallas 16
Helsinki 16
Rome 13
San Diego 11
San Giustino 11
Tokyo 11
Izmir 9
San Paolo di Civitate 9
Woodbridge 9
New York 8
Seoul 8
Bucharest 7
Den Haag 7
Melbourne 7
Seattle 7
Hanover 6
Munich 6
Nuremberg 6
Vienna 6
Abidjan 5
Nanjing 5
Newark 5
Olomouc 5
Shanghai 5
Zhengzhou 5
Amsterdam 4
Arak 4
Frankfurt Am Main 4
Lausanne 4
Philadelphia 4
Timisoara 4
Wuhan 4
Anguillara Sabazia 3
Bologna 3
Edinburgh 3
Fairfield 3
Hanoi 3
Kunming 3
Milan 3
Mit Ghamr 3
Napoli 3
San Jose 3
Simi Valley 3
São Paulo 3
Toronto 3
Turin 3
Warsaw 3
Aachen 2
Auburn Hills 2
Auckland 2
Basra 2
Brasília 2
Cairo 2
Campegine 2
Cerro Maggiore 2
Chengdu 2
Gujranwala 2
Hangzhou 2
Hefei 2
Houston 2
Islamabad 2
Jinan 2
Jundiaí 2
Kagoya 2
Leeds 2
Mcallen 2
Nanning 2
Totale 6.440
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Nome #
Structural investigation of Small Molecules Targeting Influenza A Virus Polymerase 2.105
1,4-Benzothiazine ATP-Sensitive Potassium Channel Openers: Modifications at the C-2 and C-6 Positions 240
1,2,4-triazolo[1,5-α]pyrimidines as a novel class of inhibitors of the HIV-1 reverse transcriptase-αssociated ribonuclease h activity 219
Sintesi di nuovi inibitori della pompa di efflusso NorA dello S. aureus: dalle 3-fenil-1,4-benzotiazine alle 2-fenilchinossaline 129
Derivati 2-fenilchinolonici come inibitori della pompa di efflusso NorA dello Staphylococcus aureus ciprofloxacin resistente 110
Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase 103
Structure-activity relationship study on anti-HIV 6-desfluoroquinolones. 92
Syhtesis and Biological Evaluation of 2-Phenylquinolones Targeted at Tat/TAR Recognition 90
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors 89
Targeting CDKs to inhibit the HIV-1 TAT-mediated transcription 85
Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation 83
2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction 82
Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase 82
A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors 80
A New Promising Class of pyrazolobenzothiazine inhibitors of S. aureus NorA Efflux Pump 78
2-phenylquinolones as HIV-1 Tat/TAR interaction inhibitors 77
Inhibition of Subgenomic Hepatitis C Virus RNA Replication by Acridone Derivatives: Identification of an NS3 Helicase Inhibitor. 77
CYCLOHEPTATHIOPHENE-3-CARBOXAMIDE DERIVATIVES AS INFLUENZA A VIRUS POLYMERASE INHIBITORS 77
C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors 77
Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development 77
Disegno e Sintesi di Nuovi Inibitori Allosterici della NS5B Polimerasi dell'HCV 76
A Broad Anti-influenza Hybrid Small Molecule that Potently Disrupts the Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits Interaction 76
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors 76
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B Palm Site I inhibitors case study. 76
6-Desfluoroquinolones as promising HIV transcription inhibitors 75
New Insights on KCa3.1 Channel Modulation 75
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 74
Synthesis of 2-(Arylamino)ethanethiols via Lewis Acid catalyzed Aminolysis of 2,2-Dimethylthiirane as Precursors of the 1,4-Benzothiazine Nucleus 73
New anti-ovarian cancer quinolone derivatives acting by modulating microRNA processing machinery 72
Advantageous Use of Ionic Liquids for the Synthesis of Pharmaceutically Relevant Quinolones 72
Studies on Anti-HIV Quinolones: New Insights on the C-6 Position 70
Broad-Spectrum Flavivirus Inhibitors: a Medicinal Chemistry Point of View 70
A new quinolone derivative with ultra-potent anti-HIV activity. 69
A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates 68
Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position 68
Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions 68
A New Derivative with Ultra-Potent Anti-HIV Activity 67
2-Phenylquinazolinone fragment imparts anti-CDKs and anti-HIV activities 67
The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors 67
Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors 67
Synthesis and Characterization of 1,2,4-Triazolo[1,5-a]pyrimidine-2-carboxamide-based Compounds Targeting the PA-PB1 Interface of Influenza A Virus Polymerase. 67
Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization 66
Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents 66
Evolution from a natural flavones nucleus to obtain 2-(4-Propoxyphenyl)quinoline derivatives as potent inhibitors of the S. aureus NorA efflux pump. 64
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 63
Computer-Aided Identification of Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 63
Design and synthesis of WM5 analogues as HIV-1 TAR RNA binders. 62
Discovery of Novel Inhibitors of the NorA Multidrug Transporter of Staphylococcus aureus. 61
Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues 61
New Pyrazolobenzothiazine Derivatives As Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors 60
From Quinoline to Quinazoline-Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search 60
Structure modifications of 6-aminoquinolones with potent anti-HIV activity 58
N-Benzoyl-N-methylsulfonyl anthranilates: unexpected cyclization reaction to 4-alkoxy-2,1-benzothiazines 58
A Comprehensive Structural Overview of p38 Mitogen-Activated Protein Kinase in Complex with ATP-Site and Non-ATP-Site Binders 57
Evolution of HCV NS4B Inhibitors 57
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity 55
Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 54
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor 54
6-Aminoquinolones targeting HCV NS5B polymerase. 53
Novel 1,4-Benzothiazine Derivatives as Large Conductance Ca2+-Activated Potassium Channel Openers 52
Structural Modifications of 2-phenylquinoline Inhibitors of S. aureus MDR NorA efflux pump 52
Re-evolution of the 2-phenylquinolines: Ligand-Based Design, Synthesis, and Biological Evaluation of a Potent New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors to Combat Antimicrobial Resistance 52
Co-crystal structure determination and cellular evaluation of 1,4-dihydropyrazolo[4,3-c] [1,2] benzothiazine 5,5-dioxide p38α MAPK inhibitors 52
Modulating microRNA Processing: Enoxacin, the Progenitor of a New Class of Drugs 52
Effetto Inibitorio di derivati Acridonici sulla Replicazione del virus dell’epatite C (HCV). 51
DERIVATI 2-FENIL-4-IDROSSI-CHINOLINICI COME POTENTI INBITORI DELLA POMPA D’EFFLUSSO NorA DELLO S. aureus 51
New C-6 functionalized quinoline NorA inhibitors strongly synergize with ciprofloxacin against planktonic and biofilm growing resistant Staphylococcus aureus strains 50
Novel N-benzyl-1,4-benzothiazine derivates as large conductance Ca2+-activated potassium channel activators 50
Investigation on the effect of known potent S. aureus NorA efflux pump inhibitors on the staphylococcal biofilm formation 50
Structure-Based Discovery of Pyrazolobenzothiazine Derivatives As Inhibitors of Hepatitis C Virus Replication 50
Searching New HCV NS5B Polymerase Inhibithors 49
Sustainable, three-component, one-pot procedure to obtain active anti-flavivirus agents 49
Studies of Anti-HIV Transcription Inhibitor Quinolones: Identification of Potent N1-Vinyl Derivatives 48
Structural Modifications of 2-phenylquinoline Inhibitors of S. aureus MDR NorA efflux pump 48
Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli 48
Modifications on C6 and C7 Positions of 3-Phenylquinolone Efflux Pump Inhibitors Led to Potent and Safe Antimycobacterial Treatment Adjuvants 48
Comprehensive response to usutu virus following first isolation in blood donors in the friuli venezia giulia region of italy: Development of recombinant ns1-based serology and sensitivity to antiviral drugs 48
Pyrazolo[4,3-c][1,2]benzothiazines 5,5-Dioxide: A Promising New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors 47
Cycloheptathiophene-3-carboxamide derivatives as influenza A virus polymerase inhibitors 47
New chemotypes to fight HCV infection: discovery of selective inhibitors of HCV replication with pyrazolobenzothiazine scaffold 46
Lipid nanoparticles for brain targeting III. Long-term stability and in vivo toxicity 46
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 46
Boosting Effect of 2-Phenylquinoline Efflux Inhibitors in Combination with Macrolides against Mycobacterium smegmatis and Mycobacterium avium 45
Selective anti-BVDV acridones as new potential anti-HCV agents 44
Structural optimization of the 2-Phenyl-4-hydroxyquinoline Class of S. aureus NorA Efflux Pump Inhibitors 43
Nuovi chemotipi di inibitori dell'HCV NS5B polimerasi 42
Structural investigation of the naphthyridone scaffold: identification of a 1,6-naphthyridone derivative with potent and selective anti-HIV activity. 42
Small molecole targeting HPV E6 and E7 oncoproteins expression. 42
Tumour cell population growth inhibition and cell death induction of functionalized 6-aminoquinolone derivatives 42
Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium 42
Synthesis and anti-BVDV activity of acridones as new potential antiviral agents 42
Effetto inibitorio di derivati acridonici sulla replicazione del virus dell'epatite C (HCV) 41
Discovery of the 2-phenyl-4,5,6,7-Tetrahydro-1H-indole as a novel anti-hepatitis C virus targeting scaffold 41
Enantioresolution, stereochemical characterization and biological activity of a chiral large-conductance calcium-activated potassium channel opener. 40
Targeting the HIV Tat-mediated transcriptional machinery: P-TEFb complex inhibitors 39
The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors 39
A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation 38
Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity 38
Studies on anti-HIV Quinolones 37
Structural Investigation of Cycloheptathiophene-3-carboxamide Derivatives Targeting Influenza Virus Polymerase Assembly 37
Totale 8.483
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Categoria #
all - tutte 32.297
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 32.297
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020179 0 0 0 0 0 0 0 0 68 79 8 24
2020/20211.051 13 59 35 63 241 93 109 9 87 35 44 263
2021/2022991 27 154 17 63 76 12 32 267 61 32 115 135
2022/20231.780 111 312 23 162 155 172 1 100 619 14 76 35
2023/20242.850 42 114 29 16 18 22 2.263 22 71 41 93 119
2024/20251.336 23 158 73 182 202 122 234 115 227 0 0 0
Totale 8.893