IRIS - Res&Arch Institutional Research Information System - Research & Archive

MANFRONI, GIUSEPPE
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 5.506
AS - Asia 5.467
EU - Europa 3.119
SA - Sud America 439
Continente sconosciuto - Info sul continente non disponibili 409
AF - Africa 94
OC - Oceania 10
Totale 15.044
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 5.342
CN - Cina 2.538
SG - Singapore 1.552
IT - Italia 827
IE - Irlanda 446
HK - Hong Kong 439
VN - Vietnam 423
RU - Federazione Russa 414
BR - Brasile 324
SE - Svezia 294
UA - Ucraina 275
DE - Germania 183
FR - Francia 150
FI - Finlandia 136
GB - Regno Unito 120
KR - Corea 84
CA - Canada 78
IN - India 71
BD - Bangladesh 67
BE - Belgio 65
TR - Turchia 47
JP - Giappone 41
PL - Polonia 39
MX - Messico 35
IQ - Iraq 34
AR - Argentina 32
ES - Italia 31
ZA - Sudafrica 30
NL - Olanda 27
PK - Pakistan 24
EC - Ecuador 23
ID - Indonesia 23
CH - Svizzera 19
PH - Filippine 19
CO - Colombia 18
SA - Arabia Saudita 18
UZ - Uzbekistan 18
AT - Austria 17
RO - Romania 17
CZ - Repubblica Ceca 13
EG - Egitto 12
MA - Marocco 11
VE - Venezuela 11
CL - Cile 10
SV - El Salvador 10
AU - Australia 8
LB - Libano 8
UY - Uruguay 8
AL - Albania 7
ET - Etiopia 7
HN - Honduras 7
MY - Malesia 7
CI - Costa d'Avorio 6
GT - Guatemala 6
IR - Iran 6
KE - Kenya 6
LT - Lituania 6
PE - Perù 6
TN - Tunisia 6
CR - Costa Rica 5
JO - Giordania 5
LV - Lettonia 5
AZ - Azerbaigian 4
BG - Bulgaria 4
BO - Bolivia 4
DZ - Algeria 4
EE - Estonia 4
NP - Nepal 4
OM - Oman 4
PS - Palestinian Territory 4
TH - Thailandia 4
AE - Emirati Arabi Uniti 3
AO - Angola 3
CW - ???statistics.table.value.countryCode.CW??? 3
DK - Danimarca 3
EU - Europa 3
GP - Guadalupe 3
HR - Croazia 3
IL - Israele 3
PA - Panama 3
PR - Porto Rico 3
RS - Serbia 3
SY - Repubblica araba siriana 3
TT - Trinidad e Tobago 3
BB - Barbados 2
HT - Haiti 2
KG - Kirghizistan 2
KZ - Kazakistan 2
LY - Libia 2
MD - Moldavia 2
MO - Macao, regione amministrativa speciale della Cina 2
NI - Nicaragua 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
PY - Paraguay 2
SK - Slovacchia (Repubblica Slovacca) 2
TW - Taiwan 2
VG - Isole Vergini Britanniche 2
XK - ???statistics.table.value.countryCode.XK??? 2
AM - Armenia 1
Totale 14.622
Salva come PNG Salva come JPEG
Città #
Guangzhou 2.080
Singapore 1.158
Chandler 600
San Jose 573
Ashburn 523
Dublin 446
Perugia 436
Hong Kong 427
Dong Ket 246
San Mateo 226
Santa Clara 202
Council Bluffs 172
Boardman 164
Jacksonville 139
Moscow 123
Beijing 116
Medford 103
Princeton 103
Los Angeles 100
Lauterbourg 96
Altamura 95
Ann Arbor 83
The Dalles 83
Wilmington 81
Seoul 80
New York 74
Ho Chi Minh City 66
Lawrence 66
Brussels 65
Fremont 56
Andover 53
Munich 50
São Paulo 47
Dallas 42
Orem 39
Atlanta 37
Piscataway 37
Rome 37
Hanoi 34
Tokyo 34
Redmond 32
Saint Petersburg 31
Turku 29
Warsaw 29
Dearborn 27
Phoenix 27
Montreal 26
Des Moines 25
Spoleto 25
Denver 24
Chicago 23
Helsinki 23
North Bergen 23
Redwood City 21
Falls Church 20
West Jordan 20
Brooklyn 19
Buffalo 19
Norwalk 19
Johannesburg 18
Chennai 17
Hefei 16
Baghdad 15
Columbus 15
Seattle 15
Houston 14
Nuremberg 13
Poplar 13
Toronto 13
Mexico City 12
San Francisco 12
Stockholm 12
Dhaka 11
Izmir 11
Philadelphia 11
Quito 11
San Diego 11
San Giustino 11
Amsterdam 10
Ankara 10
Brasília 10
Charlotte 10
Porto Alegre 10
Lappeenranta 9
London 9
Milan 9
Mumbai 9
Rio de Janeiro 9
San Paolo di Civitate 9
Shanghai 9
Tashkent 9
Vienna 9
Woodbridge 9
Barnet 8
Boston 8
Cairo 8
Da Nang 8
Haiphong 8
Manchester 8
San Salvador 8
Totale 10.101
Salva come PNG Salva come JPEG
Nome #
Structural investigation of Small Molecules Targeting Influenza A Virus Polymerase 2.157
1,2,4-triazolo[1,5-α]pyrimidines as a novel class of inhibitors of the HIV-1 reverse transcriptase-αssociated ribonuclease h activity 345
1,4-Benzothiazine ATP-Sensitive Potassium Channel Openers: Modifications at the C-2 and C-6 Positions 329
Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase 174
Sintesi di nuovi inibitori della pompa di efflusso NorA dello S. aureus: dalle 3-fenil-1,4-benzotiazine alle 2-fenilchinossaline 167
New anti-ovarian cancer quinolone derivatives acting by modulating microRNA processing machinery 165
C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors 160
New Insights on KCa3.1 Channel Modulation 157
A Broad Anti-influenza Hybrid Small Molecule that Potently Disrupts the Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits Interaction 153
Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors 151
Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development 146
2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction 145
A Journey around the Medicinal Chemistry of Hepatitis C Virus Inhibitors Targeting NS4B: From Target to Preclinical Drug Candidates 144
From Quinoline to Quinazoline-Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search 144
Syhtesis and Biological Evaluation of 2-Phenylquinolones Targeted at Tat/TAR Recognition 140
2-phenylquinolones as HIV-1 Tat/TAR interaction inhibitors 140
Derivati 2-fenilchinolonici come inibitori della pompa di efflusso NorA dello Staphylococcus aureus ciprofloxacin resistente 140
A New Promising Class of pyrazolobenzothiazine inhibitors of S. aureus NorA Efflux Pump 140
Broad-Spectrum Flavivirus Inhibitors: a Medicinal Chemistry Point of View 140
Pyridobenzothiazolones Exert Potent Anti-Dengue Activity by Hampering Multiple Functions of NS5 Polymerase 139
Structure-activity relationship study on anti-HIV 6-desfluoroquinolones. 134
Computer-Aided Identification of Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 134
A Comprehensive Structural Overview of p38 Mitogen-Activated Protein Kinase in Complex with ATP-Site and Non-ATP-Site Binders 134
Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation 134
A Comprehensive Structural Overview of p38α MAPK in Complex with Type I Inhibitors 132
6-Desfluoroquinolones as promising HIV transcription inhibitors 131
Discovery of Novel Inhibitors of the NorA Multidrug Transporter of Staphylococcus aureus. 128
N-Benzoyl-N-methylsulfonyl anthranilates: unexpected cyclization reaction to 4-alkoxy-2,1-benzothiazines 128
Advantageous Use of Ionic Liquids for the Synthesis of Pharmaceutically Relevant Quinolones 124
A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation 123
From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors 123
Targeting CDKs to inhibit the HIV-1 TAT-mediated transcription 122
Structure-based insights into p38α MAPK: from crystal structures analysis to hit optimization 122
Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents 122
Inhibition of Subgenomic Hepatitis C Virus RNA Replication by Acridone Derivatives: Identification of an NS3 Helicase Inhibitor. 121
Co-crystal structure determination and cellular evaluation of 1,4-dihydropyrazolo[4,3-c] [1,2] benzothiazine 5,5-dioxide p38α MAPK inhibitors 121
Design and synthesis of WM5 analogues as HIV-1 TAR RNA binders. 120
Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions 120
Evolution of HCV NS4B Inhibitors 120
Synthesis and Characterization of 1,2,4-Triazolo[1,5-a]pyrimidine-2-carboxamide-based Compounds Targeting the PA-PB1 Interface of Influenza A Virus Polymerase. 119
Structural optimization of the 2-Phenyl-4-hydroxyquinoline Class of S. aureus NorA Efflux Pump Inhibitors 117
New C-6 functionalized quinoline NorA inhibitors strongly synergize with ciprofloxacin against planktonic and biofilm growing resistant Staphylococcus aureus strains 116
Disegno e Sintesi di Nuovi Inibitori Allosterici della NS5B Polimerasi dell'HCV 116
2-Phenylquinazolinone fragment imparts anti-CDKs and anti-HIV activities 116
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B Palm Site I inhibitors case study. 116
A new quinolone derivative with ultra-potent anti-HIV activity. 115
New Pyrazolobenzothiazine Derivatives As Hepatitis C Virus NS5B Polymerase Palm Site I Inhibitors 115
Computer-Aided Design, Synthesis and Validation of 2-Phenylquinazolinone Fragments as CDK9 Inhibitors with Anti-HIV-1 Tat-Mediated Transcription Activity 114
A New Derivative with Ultra-Potent Anti-HIV Activity 113
Evolution from a natural flavones nucleus to obtain 2-(4-Propoxyphenyl)quinoline derivatives as potent inhibitors of the S. aureus NorA efflux pump. 113
CYCLOHEPTATHIOPHENE-3-CARBOXAMIDE DERIVATIVES AS INFLUENZA A VIRUS POLYMERASE INHIBITORS 113
Investigation on the effect of known potent S. aureus NorA efflux pump inhibitors on the staphylococcal biofilm formation 113
Structural Modifications of the Quinolin-4-yloxy Core to Obtain New Staphylococcus aureus NorA Inhibitors 113
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 112
Synthesis of 2-(Arylamino)ethanethiols via Lewis Acid catalyzed Aminolysis of 2,2-Dimethylthiirane as Precursors of the 1,4-Benzothiazine Nucleus 111
Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position 109
Searching for Novel Inhibitors of the S. aureus NorA Efflux Pump: Synthesis and Biological Evaluation of the 3-Phenyl-1,4-benzothiazine Analogues 108
Natural isoflavone biochanin A as a template for the design of new and potent 3-phenylquinolone efflux inhibitors against Mycobacterium avium 107
The Pyrazolobenzothiazine Core as a New Chemotype of p38 Alpha Mitogen-Activated Protein Kinase Inhibitors 106
Studies of Anti-HIV Transcription Inhibitor Quinolones: Identification of Potent N1-Vinyl Derivatives 104
Nuovi chemotipi di inibitori dell'HCV NS5B polimerasi 104
Small molecole targeting HPV E6 and E7 oncoproteins expression. 104
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 102
6-Aminoquinolones targeting HCV NS5B polymerase. 102
Comprehensive response to usutu virus following first isolation in blood donors in the friuli venezia giulia region of italy: Development of recombinant ns1-based serology and sensitivity to antiviral drugs 101
Modulating microRNA Processing: Enoxacin, the Progenitor of a New Class of Drugs 101
Sustainable, three-component, one-pot procedure to obtain active anti-flavivirus agents 101
TARGETING CDKs TO INHIBIT THE HIV-1 TAT-MEDIATED TRANSCRIPTION 100
Modifications on C6 and C7 Positions of 3-Phenylquinolone Efflux Pump Inhibitors Led to Potent and Safe Antimycobacterial Treatment Adjuvants 99
Functionalized sulfonyl anthranilic acid derivatives inhibit replication of all the four dengue serotypes 98
Structure modifications of 6-aminoquinolones with potent anti-HIV activity 98
Studies on Anti-HIV Quinolones: New Insights on the C-6 Position 98
Lipid nanoparticles for brain targeting III. Long-term stability and in vivo toxicity 98
Structural Modifications of 2-phenylquinoline Inhibitors of S. aureus MDR NorA efflux pump 97
Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor 97
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity 97
Searching New HCV NS5B Polymerase Inhibithors 92
Structural Modifications of 2-phenylquinoline Inhibitors of S. aureus MDR NorA efflux pump 91
Boosting Effect of 2-Phenylquinoline Efflux Inhibitors in Combination with Macrolides against Mycobacterium smegmatis and Mycobacterium avium 91
Cycloheptathiophene-3-carboxamide derivatives as influenza A virus polymerase inhibitors 90
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 90
Novel 1,4-Benzothiazine Derivatives as Large Conductance Ca2+-Activated Potassium Channel Openers 89
Structural Investigation of Cycloheptathiophene-3-carboxamide Derivatives Targeting Influenza Virus Polymerase Assembly 89
NorA Efflux Pump Inhibitors: Expanding SAR Knowledge of Pyrazolo[4,3‐c][1,2]benzothiazine 5,5‐Dioxide Derivatives 88
Structural investigation of the naphthyridone scaffold: identification of a 1,6-naphthyridone derivative with potent and selective anti-HIV activity. 87
Discovery of 2‐phenylquinazolines as potent Mycobacterium avium efflux pump inhibitors able to synergize with clarithromycin against clinical isolate 85
Small Molecule Drugs Targeting Viral Polymerases 85
Re-evolution of the 2-phenylquinolines: Ligand-Based Design, Synthesis, and Biological Evaluation of a Potent New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors to Combat Antimicrobial Resistance 85
Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli 85
New chemotypes to fight HCV infection: discovery of selective inhibitors of HCV replication with pyrazolobenzothiazine scaffold 83
Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity 82
Novel N-benzyl-1,4-benzothiazine derivates as large conductance Ca2+-activated potassium channel activators 80
Structure-Based Discovery of Pyrazolobenzothiazine Derivatives As Inhibitors of Hepatitis C Virus Replication 80
Virucidal Activity of the Pyridobenzothiazolone Derivative HeE1-17Y against Enveloped RNA Viruses 79
DERIVATI 2-FENIL-4-IDROSSI-CHINOLINICI COME POTENTI INBITORI DELLA POMPA D’EFFLUSSO NorA DELLO S. aureus 79
Effetto inibitorio di derivati acridonici sulla replicazione del virus dell'epatite C (HCV) 77
Selective anti-BVDV acridones as new potential anti-HCV agents 77
Pyrazolo[4,3-c][1,2]benzothiazines 5,5-Dioxide: A Promising New Class of Staphylococcus aureus NorA Efflux Pump Inhibitors 74
Targeting the HIV Tat-mediated transcriptional machinery: P-TEFb complex inhibitors 74
Discovery of the 2-phenyl-4,5,6,7-Tetrahydro-1H-indole as a novel anti-hepatitis C virus targeting scaffold 74
Totale 13.738
Salva come PNG Salva come JPEG
Categoria #
all - tutte 58.743
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 58.743
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022793 0 0 0 63 76 12 32 267 61 32 115 135
2022/20231.780 111 312 23 162 155 172 1 100 619 14 76 35
2023/20242.850 42 114 29 16 18 22 2.263 22 71 41 93 119
2024/20251.962 23 158 73 182 202 122 233 114 335 103 280 137
2025/20264.282 265 248 191 507 589 416 742 236 480 351 186 71
2026/20271.243 105 128 273 737 0 0 0 0 0 0 0 0
Totale 15.044