IRIS - Res&Arch Institutional Research Information System - Research & Archive

PELLICCIARI, Roberto
 Distribuzione geografica
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Continente #
NA - Nord America 12.024
EU - Europa 7.816
AS - Asia 7.264
SA - Sud America 1.158
Continente sconosciuto - Info sul continente non disponibili 721
AF - Africa 172
OC - Oceania 10
Totale 29.165
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Nazione #
US - Stati Uniti d'America 11.588
SG - Singapore 3.323
UA - Ucraina 1.752
IE - Irlanda 1.222
RU - Federazione Russa 1.036
CN - Cina 944
IT - Italia 939
HK - Hong Kong 916
BR - Brasile 875
SE - Svezia 862
VN - Vietnam 702
DE - Germania 524
FI - Finlandia 406
FR - Francia 381
KR - Corea 305
GB - Regno Unito 249
TR - Turchia 235
CA - Canada 192
IN - India 168
BD - Bangladesh 134
AR - Argentina 95
JP - Giappone 79
MX - Messico 71
CO - Colombia 66
PL - Polonia 62
CH - Svizzera 60
NL - Olanda 59
IQ - Iraq 58
BE - Belgio 50
UZ - Uzbekistan 50
PK - Pakistan 44
ES - Italia 43
ZA - Sudafrica 43
AT - Austria 36
CZ - Repubblica Ceca 36
ID - Indonesia 36
PH - Filippine 35
SA - Arabia Saudita 35
EC - Ecuador 33
VE - Venezuela 32
JM - Giamaica 31
IL - Israele 29
CR - Costa Rica 28
LB - Libano 24
EG - Egitto 21
JO - Giordania 21
HN - Honduras 20
MY - Malesia 20
ET - Etiopia 19
LT - Lituania 19
MA - Marocco 17
AE - Emirati Arabi Uniti 16
CW - ???statistics.table.value.countryCode.CW??? 16
GT - Guatemala 16
SV - El Salvador 16
CL - Cile 15
PY - Paraguay 15
NI - Nicaragua 14
BG - Bulgaria 13
GR - Grecia 13
EU - Europa 12
TN - Tunisia 12
TT - Trinidad e Tobago 12
AZ - Azerbaigian 11
NP - Nepal 11
DZ - Algeria 10
PR - Porto Rico 10
KE - Kenya 9
OM - Oman 9
PE - Perù 9
SC - Seychelles 9
UY - Uruguay 9
PS - Palestinian Territory 8
AU - Australia 7
BO - Bolivia 7
KW - Kuwait 7
AL - Albania 6
AM - Armenia 6
DK - Danimarca 6
GP - Guadalupe 6
KZ - Kazakistan 6
NO - Norvegia 6
RS - Serbia 6
LY - Libia 5
PA - Panama 5
PT - Portogallo 5
QA - Qatar 5
BB - Barbados 4
GE - Georgia 4
HR - Croazia 4
NG - Nigeria 4
SK - Slovacchia (Repubblica Slovacca) 4
SN - Senegal 4
TH - Thailandia 4
TW - Taiwan 4
BY - Bielorussia 3
DO - Repubblica Dominicana 3
MU - Mauritius 3
NZ - Nuova Zelanda 3
RO - Romania 3
Totale 28.420
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Città #
Singapore 2.183
Dublin 1.221
Chandler 1.206
Jacksonville 1.010
San Jose 976
Hong Kong 911
Ashburn 905
San Mateo 705
Santa Clara 489
Boardman 453
Council Bluffs 401
Dong Ket 385
Moscow 374
Medford 314
Princeton 312
Seoul 302
Lauterbourg 288
Wilmington 245
Beijing 218
Andover 206
Ann Arbor 193
Los Angeles 183
Altamura 168
Izmir 166
Perugia 160
Lawrence 132
New York 127
Des Moines 121
São Paulo 115
Munich 111
Piscataway 102
Ho Chi Minh City 101
The Dalles 93
Saint Petersburg 88
Hanoi 73
Washington 73
Dallas 70
Tokyo 69
Rome 63
Helsinki 59
Norwalk 59
Phoenix 56
Woodbridge 56
Orem 54
Brussels 46
Montreal 41
Turku 41
Brooklyn 40
Chennai 40
Milan 40
Atlanta 39
Toronto 39
Nanjing 38
Houston 37
Shanghai 37
Chicago 36
Warsaw 36
North Bergen 35
Auburn Hills 34
London 30
Naples 30
Tashkent 30
Denver 29
Manchester 28
Rio de Janeiro 28
San Paolo di Civitate 28
Boston 27
Mexico City 27
Johannesburg 26
Stockholm 26
Belo Horizonte 25
Baghdad 23
Buffalo 23
Columbus 23
Ambler 22
San Francisco 22
Charlotte 21
Poplar 21
Amsterdam 20
Brasília 20
Falls Church 20
Kingston 20
Philadelphia 20
Addis Ababa 19
Ankara 19
Brno 19
Frankfurt am Main 18
New Delhi 18
Redwood City 18
Amman 17
Medellín 17
Mumbai 17
San José 17
Den Haag 16
Lahore 16
Seattle 16
Willemstad 16
Bologna 15
Riyadh 15
San Salvador 15
Totale 17.052
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Nome #
2-Amino-4,5-methyleneadipic Acid Compounds for Treatment of CNS Disorders 280
1-AMINOINDAN-1,5-DICARBOXYLIC ACID - A NOVEL ANTAGONIST AT PHOSPHOLIPASE C-LINKED METABOTROPIC GLUTAMATE RECEPTORS 235
Asymmetric synthesis of (2R, 1’S, 2’R, 3’S)-2-(2’- Carboxy-3’-phenylcyclopropyl)glicine (PCCG 13), the first selective antagonist of metabotropic glutamate receptors coupled phospholipase D 202
Discovery and Structure–Activity Relationships of Novel ssDAF-12 Receptor Modulators 185
Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor 176
AMINO-ACID DERIVATIVES OF 5-ASA AS NOVEL PRODRUGS FOR INTESTINAL DRUG-DELIVERY 162
5-ASA-glutamate protects rats from inflammaory bowel disease induced by intracolonic administration of trinitrobenzensulfonic acid. 153
9. The Systems Biology of Transporters – Targeting the Regulatory System for Transporters (FXR/RXR) 151
A farnesoid X receptor-small heterodimer partner regulatory cascade modulates tissue metallproteinase inhibitor-1 and matrix metallprotease expression in hepatic stellate cells and promotes resolution of liver fibrosis’ 146
Molecular field analysis and 3D-quantitative structure-activity relationship study (MFA 3D-QSAR) unveil novel features of bile acid recognition at TGR5. 145
Avicholic Acid: A Primary Bile Acid from Birds on the Route to Potent and Selective TGR5 Ligands 142
Adamantyl-substituted retinoid-derived molecules that intercact with the orphan nuclear receptor small heterodimer partner:effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis, and inhibition of SRC homology 2 domain-containing protein tyrosine phosphatase-2 activity 139
Enantioselective Synthesis of Naturally Occurring trans-4-Hydroxy-S-pipecolic Acid-4-sulfate, a New Potent and Selective NMDA Receptor Agonist 139
(S)-Benzyl-O-Serine (S-BOS), a new chiral selector for ligand-exchange chromatography of amino acids. 139
1μs Molecular Dynamics Simulations to study the poisoning effect of the PARP-1 full length enzyme 139
a-Amino-b-carboxymuconate-e-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of de Novo Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis 138
Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication 137
Alternative strategies for targeting mouse double minute 2 activity with small molecules: novel patents on the horizon? 137
6a-Ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity. 136
(S)-(-)-alpha,alpha-Di(2-naphthyl)-2-pyrrolidine Methanol, a Useful Tool to Study the Recognition Mechanism in Chiral Ligand-Exchange Chromatography (CLEC) 135
Spiro[2.2]pentane as a dyssymetric scaffold for conformationally constrained analogues of glutamic acid: diastereodivergent synthesis of 1-aminospiro[2.2]pentyl-1,4-dicarboxylic acids 135
Side chain modified HDCA derivatives: synthesis, CMC determination and molecular modelling studies. 135
Binding Mode of 6ECDCA, a Potent Bile Acid Agonist of the Farnesoid X Receptor (FXR) 134
Asymmetric Synthesis of Enantiomerically Pure (2S,1'S,2'S,3'R)-Phenylcarboxycyclopropylglycine (PCCG-4): a Potent and Selective Ligand at Group II Metabotropic Glutamate Receptors 132
23-METHYL-3-ALPHA,7-BETA-DIHYDROXY-5-BETA-CHOLAN-24-OIC ACID - DOSE-RESPONSE STUDY OF BILIARY-SECRETION IN RAT 131
(S)-(-)-a,a-Di(2-naphthyl)-2-pyrrolidine Methanol, a useful tool to study the recognition mechanism in chiral ligand-exchange chromatography (CLEC) 129
Spiro[2.2]pentane as a Dissymmetric Scaffold for Conformationally Constrained Analogues of Glutamic Acid: Focus on Racemic 1-Aminospiro[2.2]pentyl-1,4-dicarboxylic Acids 128
(2R,1’S,2’R,3’S)-2-(2’-Carboxy-3’-phenylcyclopropyl)glycine (PCCG-13), the First Potent and Selective Competitive Antagonist of Phospholipase D-Coupled Metabotropic Glutamate Receptors: Asymmetric Synthesis and Preliminary Biological Properties 128
Asymmetric synthesis of the four diastereoisomers of a novel non-steroidal farnesoid X receptor (FXR) agonist: Role of the chirality on the biological activity 128
Analisi HPLC/ELSD di Acidi Biliari Amidati: un Approccio Efficace Per Assistere Processi Sintetici a Flusso Continuo 127
BF3·Et2O-Promoted Decomposition of Cyclic α-Diazo-β-Hydroxy Ketones: Novel Insights into Mechanistic Aspects 127
BF3•Et2O-Induced Decomposition of Ethyl 2-Diazo-3-hydroxy-3,3-diarylpropanoates in Acetonitrile: A Novel Approach to 2,3-Diaryl β-Enamino Ester Derivatives 126
Targeting the FXR nuclear receptor through a virtual screening approach 126
"*-Diazocarbonyl Chemistry - Target Driven Applications" 125
Towards New Neuroprotective Agents: Design and Synthesis of Thieno[2,3-c]-isoquinolinon-5-one as a Potent PARP-1 Inhibitor. 125
A new computational model to predict the elution order in the chiral ligand-exchange chromatography (CLEC) of amino acids 125
Structure of Metal-Carbenoid Intermediates Derived from the Dirhodium(II)Tetracarboxylate Mediated Decomposition of ?-Diazocarbonyl Compounds. An ab initio and DTF Study 124
Insights into Phenylalanine Derivatives Recognition of VLA-4 Integrin: from a Pharmacophoric Study to 3D-QSAR and Molecular Docking Analyses 124
7alfa-OH Epimerisation of Bile Acids via Oxido-reduction with Xanthomonas maltophilia 124
Exploiting Chemical Toolboxes for the Expedited Generation of Tetracyclic Quinolines as a Novel Class of PXR Agonists 124
Novel Potent and Selective Bile Acid Derivatives as TGR5 Agonists: Biological Screening, Structure-Activity Relationships and Molecular Modeling Studies 122
Design, Synthesis and Preliminay Evaluation of Novel 3’-Substituted Carboxycyclopropylglycines as Antagonists at Group 2 Metabotropic Glutamate Receptors 122
Avicholic acid: a lead compound from birds on the route to potent TGR5 modulators 122
Design and synthesis of 4H-thieno[2,3-c]isoquinolin-5-one derivatives as potent PARP-1 inhibitors, on route of new antiischemic agents 122
On the way to selective PARP-2 inhibitors. Design, synthesis, and preliminary evaluation of a series of isoquinolinone derivatives. 121
Bile Acids Signal via TGR5 to Activate Intestinal Stem Cells and Epithelial Regeneration 121
(2S,1'S, 2'S, 3'R)-2-(2'-carboxy,3'-phenylcyclopropyl)glycine, a potent and selective antagonist of type 2 metabotropic glutamate receptors, 120
Chromatographic separation and evaluation of the lipophilicity by reversed-phase high-performance liquid chromatography of fullerene-C60 derivatives 118
An essential role of Farnesoid X-Receptor in regulating intestinal fibrosis in murine model of chronic colitis 118
Synthesis, molecular modeling studies, and preliminary pharmacological characterization of all possible 2-(2'-sulfonocyclopropyl)glycine stereoisomers as conformationally constrained L-homocysteic acid analogs. 117
Side-chain Modified Bile Acids: Chromatographic Separation of 23-Methyl Epimers 117
Modulators of the kynurenine pathway of triptophan metabolism. Synthesis and preliminary biological evaluation of (S)-4-(ethylsulfonyl)benzoylalanine, the first potent and selective kynurenine aminotransferse II (KAT II) inhibitor 117
Acidi Biliari Ossidrilati in Catena Laterale 117
BILE-ACIDS WITH A CYCLOPROPYL-CONTAINING SIDE-CHAIN .4. PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES OF THE 4 DIASTEREOISOMERS OF 3-ALPHA,7-BETA-DIHYDROXY-22,23-METHYLENE-5-BETA-CHOLAN-24-OIC ACID 117
Metabotropic glutamate receptors: structure and new subtype-selective ligands 116
Beyond Bile Acids: Targeting Farnesoid X Receptor (FXR) with Natural and Synthetic Ligands 116
Dirhodium(II)-tetraacetate-Mediated Decomposition of Ethyldiazo- acetate and Ethyldiazomalonate in the Presence of Fullerene. A New Procedure for the Selective Synthesis of [6-6]-Closed Methanofullerenes 115
Discovery of 6α-Ethyl-23(S)-methyl-cholic Acid (S-EMCA, INT-777) as a Potent and Selective Agonist for the TGR5 Receptor, a Novel Target for Diabesity 115
Dynamic Ligand-Exchange Chiral Stationary Phase from S-Benzyl-(R)-cysteine 113
Design, Molecular Modeling Studies, Synthesis and Preliminary Evaluation of Novel PARP-1 Inhibitors on the Road of Antiischemic Agents 113
Chromatographic hydrophobicity index: a high-throughput tool to estimate the critical micellar concentration of bile acids 113
Indium triflate catalyzed reaction of diisopropyl diazomethylphophonate with imines as a new approach to cis- and trans-aziridine-2-phosphonates 111
3,4-Cyclopropyl-glutamates as N-Methyl-D-aspartate Receptor Ligands 111
C-3-fullero-tris-methanodicarboxylic acid protects cerebellar granule cells from apoptosis 111
Chiral ligand-exchange separation and resolution ofextremely rigid glutamate analogs: 1-aminospiro[2.2]pentyl-1,4-dicarboxylicacids. 110
Preparation and Physicochemical Properties of Natural (23R)-3alpha,7alpha,23- and (23R)-3alpha,12alpha,23-Trihydroxylated Bile Acids and Their (23S)-Epimers 110
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy. 110
'On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo’ 109
C3-Fullero-tris-methanodicarboxylic acid protects epithelial cells from radiation induced anoikia by influencing cell adhesion ability 109
A new synthesis of carboxyterfenadine (fexofenadine) and its bioisoteric tetrazole analogs 109
Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage 109
TGR5-mediated bile acid sensing controls glucose homeostasis. 109
Definition of a pharmacophore for the metabotropic glutamate receptors negatively linked to adenylyl cyclase 109
Novel stereoselective synthesis and chromatographic evaluation of E-guggulsterone 109
Effects of Molecular Dynamics and Replica Exchange Molecular Dynamics in Sampling the Conformational Space of PARP-1 109
Sequence variants in kynurenine aminotransferase II (KAT II) orthologs determine different potencies of the inhibitor S-ESBA 109
S-(+)-2-(3'carboxy-bicyclo[1.1.1]pentyl)glycine, a structurally new group I metabotropic glutamate receptor antagonist 108
New one-pot synthesis of pyrazole-5-carboxylates by 1,3-dipole cycloadditions of ethyl diazoacetate with α-methylene carbonyl compunds 108
Modeling of Poly(ADP-ribose)polymerase (PARP) Inhibitors. Docking of Ligands and QSAR 108
Targeting the Conformational Transitions of MDM2 and MDMX. PART I: Insights into Dissimilarities and Similarities of p53 Recognition 108
Rat brain guanosine binding site. Biological studies and pseudo-Receptor construction 107
BILE-ACIDS WITH A CYCLOPROPYL-CONTAINING SIDE-CHAIN .3. SEPARATION, IDENTIFICATION, AND PROPERTIES OF ALL 4 STEREOISOMERS OF 3-ALPHA,7-BETA-DIHYDROXY-22,23-METHYLENE-5-BETA-CHOLAN-24-OIC ACID 107
Rat Brain Guanosine Binding Site:Biological Studies and Pseudo Receptor Construction 106
Evaluation of the enantiomeric selectivity in the Chiral Ligand-Exchange Chromatography of amino acids by a computational model 106
Binding modes of noncompetitive AMPA Antagonists: A computational approach 106
An efficient procedure for the regiospecific preparation of D-homo-steroid derivatives. 106
Administration of 3 alpha-6 alpha-dihydroxy-7a alpha-fluoro-5 beta-cholanoate (UPF-680) in chronic cholestasis induced by 17 alpha-ethynyl-estradiol (17 alpha EE) in rats. 106
A new aminoacid derivative of ursodeoxycholate, N-L-glutamyl-UDCA (UDCA-glu) to release selectively UDCA in the rat colon. 106
Development of 3α, 7α-dihydroxy-6α-ethyl-24-nor-5β-cholan-23-sulfate sodium salt (INT-767): Process optimization, synthesis and characterization of metabolites 105
Novel PARP Inhibitors: Synthesis and Molecular Modeling Studies 105
S-Trityl-(R)-cysteine, a powerful chiral selector for the analytical and preparative ligand-exchange chromatography of amino acids 104
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy 104
Insights in the PARP1 poisoning effect 104
Poly(ADP-ribose)-Polimerase-Catalyzed Hydrolysis of NAD+: QM/MM Simulation of the Enzyme Reaction 103
‘Exploring the metal-catalyzed reaction of furans with alkyl α-diazomethanesulfonate and α-diazomethanephosphonate: Synthesis of ω-acyl- substituted sulfono- and phosphonobutadienes’ 103
Bile acids: property-activity relationship and molecular modelling studies 103
HOMOLYTIC SUBSTITUTION AND CARBENOIDIC REACTIONS IN THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES OF PHARMACEUTICAL INTEREST - SYNTHESIS AND PROPERTIES OF (2-CYCLOALKYL-1-BENZIMIDAZOLYL)-N,N-DIETHYLACETAMIDES 103
Molecular determinats for metabotropic glutamate receptor activation and blockade. Molecular dynamics and electrostatic potential analysis studies 103
Application of Untargeted and Targeted Metabolomics to the Study of Liver Disease Caused by a Deficiency in HSD3B7-diagnosis and Response to Therapy 103
O-Benzyl-(S)-Serine, a New Chiral Selector for Ligand-Exchange Chromatography of Amino Acids 103
Totale 12.414
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Categoria #
all - tutte 129.099
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 129.099
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.914 0 0 0 194 80 24 17 883 22 55 288 351
2022/20234.047 339 482 49 295 424 477 8 186 1.593 10 144 40
2023/20241.511 95 201 97 20 12 17 260 37 221 51 223 277
2024/20254.029 81 402 178 176 522 139 106 287 865 247 636 390
2025/20268.268 670 715 388 964 988 801 1.516 373 870 696 191 96
2026/20272.908 178 284 516 1.930 0 0 0 0 0 0 0 0
Totale 29.165