IRIS - Res&Arch Institutional Research Information System - Research & Archive

PELLICCIARI, Roberto
 Distribuzione geografica
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Continente #
NA - Nord America 9.782
EU - Europa 7.375
AS - Asia 7.105
SA - Sud America 1.100
AF - Africa 162
Continente sconosciuto - Info sul continente non disponibili 13
OC - Oceania 9
Totale 25.546
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Nazione #
US - Stati Uniti d'America 9.572
SG - Singapore 3.264
UA - Ucraina 1.749
IE - Irlanda 1.222
RU - Federazione Russa 1.010
CN - Cina 917
HK - Hong Kong 909
SE - Svezia 858
BR - Brasile 847
VN - Vietnam 697
IT - Italia 584
DE - Germania 518
FI - Finlandia 406
FR - Francia 373
KR - Corea 305
TR - Turchia 234
GB - Regno Unito 229
IN - India 166
BD - Bangladesh 127
CA - Canada 93
AR - Argentina 87
JP - Giappone 78
MX - Messico 66
PL - Polonia 62
CH - Svizzera 60
IQ - Iraq 58
NL - Olanda 58
CO - Colombia 52
BE - Belgio 50
UZ - Uzbekistan 50
PK - Pakistan 43
ZA - Sudafrica 43
ES - Italia 37
AT - Austria 36
CZ - Repubblica Ceca 33
SA - Arabia Saudita 33
PH - Filippine 31
EC - Ecuador 29
ID - Indonesia 29
VE - Venezuela 28
LB - Libano 24
EG - Egitto 21
JO - Giordania 21
ET - Etiopia 19
JM - Giamaica 18
LT - Lituania 18
MA - Marocco 17
AE - Emirati Arabi Uniti 16
CL - Cile 15
MY - Malesia 15
PY - Paraguay 15
BG - Bulgaria 13
GR - Grecia 13
EU - Europa 12
IL - Israele 12
TN - Tunisia 12
AZ - Azerbaigian 10
DZ - Algeria 9
KE - Kenya 9
OM - Oman 9
PE - Perù 9
UY - Uruguay 9
NP - Nepal 8
AU - Australia 7
BO - Bolivia 7
PS - Palestinian Territory 7
CR - Costa Rica 6
KW - Kuwait 6
KZ - Kazakistan 6
AL - Albania 5
HN - Honduras 5
LY - Libia 5
NO - Norvegia 5
PA - Panama 5
PT - Portogallo 5
QA - Qatar 5
RS - Serbia 5
DK - Danimarca 4
GE - Georgia 4
HR - Croazia 4
NG - Nigeria 4
SK - Slovacchia (Repubblica Slovacca) 4
SN - Senegal 4
TW - Taiwan 4
AM - Armenia 3
BB - Barbados 3
MU - Mauritius 3
RO - Romania 3
SV - El Salvador 3
TH - Thailandia 3
BA - Bosnia-Erzegovina 2
BW - Botswana 2
BY - Bielorussia 2
CG - Congo 2
CI - Costa d'Avorio 2
DM - Dominica 2
DO - Repubblica Dominicana 2
GH - Ghana 2
GT - Guatemala 2
IR - Iran 2
Totale 25.512
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Città #
Singapore 2.172
Dublin 1.221
Chandler 1.206
Jacksonville 1.002
Hong Kong 906
San Jose 848
San Mateo 705
Ashburn 530
Boardman 453
Santa Clara 406
Dong Ket 385
Moscow 374
Medford 313
Princeton 311
Seoul 302
Lauterbourg 288
Wilmington 245
Andover 206
Beijing 205
Ann Arbor 193
Altamura 167
Izmir 166
Perugia 158
Los Angeles 147
Lawrence 132
Des Moines 121
Munich 111
New York 106
São Paulo 104
Ho Chi Minh City 101
Piscataway 95
The Dalles 93
Saint Petersburg 88
Hanoi 70
Tokyo 68
Helsinki 59
Norwalk 58
Woodbridge 56
Orem 51
Brussels 46
Turku 41
Chennai 40
Nanjing 38
Brooklyn 36
Dallas 36
Warsaw 36
Shanghai 35
Auburn Hills 34
London 30
Tashkent 30
Chicago 29
Rio de Janeiro 28
San Paolo di Civitate 28
Boston 27
Denver 27
Manchester 27
Montreal 27
Johannesburg 26
Belo Horizonte 25
Mexico City 25
Phoenix 25
Baghdad 23
Stockholm 23
Ambler 22
Houston 22
Atlanta 21
Columbus 21
Poplar 21
Falls Church 20
Rome 20
San Francisco 20
Toronto 20
Addis Ababa 19
Amsterdam 19
Ankara 18
Brno 18
Frankfurt am Main 18
New Delhi 18
Redwood City 18
Amman 17
Mumbai 17
Den Haag 16
Lahore 16
Medellín 16
Philadelphia 16
Brasília 15
Riyadh 15
Da Nang 14
Dhaka 14
Hanover 14
Nuremberg 14
Ottawa 14
Seattle 14
Charlotte 13
Curitiba 13
Frankfurt Am Main 13
Cairo 12
Chongqing 12
Delhi 12
Milan 11
Totale 15.577
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Nome #
2-Amino-4,5-methyleneadipic Acid Compounds for Treatment of CNS Disorders 266
1-AMINOINDAN-1,5-DICARBOXYLIC ACID - A NOVEL ANTAGONIST AT PHOSPHOLIPASE C-LINKED METABOTROPIC GLUTAMATE RECEPTORS 222
Asymmetric synthesis of (2R, 1’S, 2’R, 3’S)-2-(2’- Carboxy-3’-phenylcyclopropyl)glicine (PCCG 13), the first selective antagonist of metabotropic glutamate receptors coupled phospholipase D 177
Discovery and Structure–Activity Relationships of Novel ssDAF-12 Receptor Modulators 170
Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor 156
AMINO-ACID DERIVATIVES OF 5-ASA AS NOVEL PRODRUGS FOR INTESTINAL DRUG-DELIVERY 153
5-ASA-glutamate protects rats from inflammaory bowel disease induced by intracolonic administration of trinitrobenzensulfonic acid. 146
9. The Systems Biology of Transporters – Targeting the Regulatory System for Transporters (FXR/RXR) 141
Molecular field analysis and 3D-quantitative structure-activity relationship study (MFA 3D-QSAR) unveil novel features of bile acid recognition at TGR5. 139
Avicholic Acid: A Primary Bile Acid from Birds on the Route to Potent and Selective TGR5 Ligands 134
A farnesoid X receptor-small heterodimer partner regulatory cascade modulates tissue metallproteinase inhibitor-1 and matrix metallprotease expression in hepatic stellate cells and promotes resolution of liver fibrosis’ 133
(S)-Benzyl-O-Serine (S-BOS), a new chiral selector for ligand-exchange chromatography of amino acids. 133
Adamantyl-substituted retinoid-derived molecules that intercact with the orphan nuclear receptor small heterodimer partner:effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis, and inhibition of SRC homology 2 domain-containing protein tyrosine phosphatase-2 activity 131
Enantioselective Synthesis of Naturally Occurring trans-4-Hydroxy-S-pipecolic Acid-4-sulfate, a New Potent and Selective NMDA Receptor Agonist 129
(S)-(-)-alpha,alpha-Di(2-naphthyl)-2-pyrrolidine Methanol, a Useful Tool to Study the Recognition Mechanism in Chiral Ligand-Exchange Chromatography (CLEC) 126
Asymmetric Synthesis of Enantiomerically Pure (2S,1'S,2'S,3'R)-Phenylcarboxycyclopropylglycine (PCCG-4): a Potent and Selective Ligand at Group II Metabotropic Glutamate Receptors 125
6a-Ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity. 125
(2R,1’S,2’R,3’S)-2-(2’-Carboxy-3’-phenylcyclopropyl)glycine (PCCG-13), the First Potent and Selective Competitive Antagonist of Phospholipase D-Coupled Metabotropic Glutamate Receptors: Asymmetric Synthesis and Preliminary Biological Properties 123
23-METHYL-3-ALPHA,7-BETA-DIHYDROXY-5-BETA-CHOLAN-24-OIC ACID - DOSE-RESPONSE STUDY OF BILIARY-SECRETION IN RAT 123
Binding Mode of 6ECDCA, a Potent Bile Acid Agonist of the Farnesoid X Receptor (FXR) 121
Alternative strategies for targeting mouse double minute 2 activity with small molecules: novel patents on the horizon? 121
Analisi HPLC/ELSD di Acidi Biliari Amidati: un Approccio Efficace Per Assistere Processi Sintetici a Flusso Continuo 121
Asymmetric synthesis of the four diastereoisomers of a novel non-steroidal farnesoid X receptor (FXR) agonist: Role of the chirality on the biological activity 120
a-Amino-b-carboxymuconate-e-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of de Novo Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis 120
(S)-(-)-a,a-Di(2-naphthyl)-2-pyrrolidine Methanol, a useful tool to study the recognition mechanism in chiral ligand-exchange chromatography (CLEC) 119
Side chain modified HDCA derivatives: synthesis, CMC determination and molecular modelling studies. 119
Spiro[2.2]pentane as a Dissymmetric Scaffold for Conformationally Constrained Analogues of Glutamic Acid: Focus on Racemic 1-Aminospiro[2.2]pentyl-1,4-dicarboxylic Acids 118
Structure of Metal-Carbenoid Intermediates Derived from the Dirhodium(II)Tetracarboxylate Mediated Decomposition of ?-Diazocarbonyl Compounds. An ab initio and DTF Study 117
Towards New Neuroprotective Agents: Design and Synthesis of Thieno[2,3-c]-isoquinolinon-5-one as a Potent PARP-1 Inhibitor. 117
Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication 116
7alfa-OH Epimerisation of Bile Acids via Oxido-reduction with Xanthomonas maltophilia 116
BF3•Et2O-Induced Decomposition of Ethyl 2-Diazo-3-hydroxy-3,3-diarylpropanoates in Acetonitrile: A Novel Approach to 2,3-Diaryl β-Enamino Ester Derivatives 116
A new computational model to predict the elution order in the chiral ligand-exchange chromatography (CLEC) of amino acids 116
1μs Molecular Dynamics Simulations to study the poisoning effect of the PARP-1 full length enzyme 115
Spiro[2.2]pentane as a dyssymetric scaffold for conformationally constrained analogues of glutamic acid: diastereodivergent synthesis of 1-aminospiro[2.2]pentyl-1,4-dicarboxylic acids 114
An essential role of Farnesoid X-Receptor in regulating intestinal fibrosis in murine model of chronic colitis 114
Novel Potent and Selective Bile Acid Derivatives as TGR5 Agonists: Biological Screening, Structure-Activity Relationships and Molecular Modeling Studies 113
(2S,1'S, 2'S, 3'R)-2-(2'-carboxy,3'-phenylcyclopropyl)glycine, a potent and selective antagonist of type 2 metabotropic glutamate receptors, 113
Insights into Phenylalanine Derivatives Recognition of VLA-4 Integrin: from a Pharmacophoric Study to 3D-QSAR and Molecular Docking Analyses 113
Chromatographic separation and evaluation of the lipophilicity by reversed-phase high-performance liquid chromatography of fullerene-C60 derivatives 113
"*-Diazocarbonyl Chemistry - Target Driven Applications" 111
Design, Synthesis and Preliminay Evaluation of Novel 3’-Substituted Carboxycyclopropylglycines as Antagonists at Group 2 Metabotropic Glutamate Receptors 111
BF3·Et2O-Promoted Decomposition of Cyclic α-Diazo-β-Hydroxy Ketones: Novel Insights into Mechanistic Aspects 111
Metabotropic glutamate receptors: structure and new subtype-selective ligands 109
Targeting the FXR nuclear receptor through a virtual screening approach 109
Synthesis, molecular modeling studies, and preliminary pharmacological characterization of all possible 2-(2'-sulfonocyclopropyl)glycine stereoisomers as conformationally constrained L-homocysteic acid analogs. 108
Acidi Biliari Ossidrilati in Catena Laterale 108
Beyond Bile Acids: Targeting Farnesoid X Receptor (FXR) with Natural and Synthetic Ligands 108
On the way to selective PARP-2 inhibitors. Design, synthesis, and preliminary evaluation of a series of isoquinolinone derivatives. 106
Design and synthesis of 4H-thieno[2,3-c]isoquinolin-5-one derivatives as potent PARP-1 inhibitors, on route of new antiischemic agents 105
Dirhodium(II)-tetraacetate-Mediated Decomposition of Ethyldiazo- acetate and Ethyldiazomalonate in the Presence of Fullerene. A New Procedure for the Selective Synthesis of [6-6]-Closed Methanofullerenes 104
Side-chain Modified Bile Acids: Chromatographic Separation of 23-Methyl Epimers 104
Design, Molecular Modeling Studies, Synthesis and Preliminary Evaluation of Novel PARP-1 Inhibitors on the Road of Antiischemic Agents 104
Chromatographic hydrophobicity index: a high-throughput tool to estimate the critical micellar concentration of bile acids 104
Discovery of 6α-Ethyl-23(S)-methyl-cholic Acid (S-EMCA, INT-777) as a Potent and Selective Agonist for the TGR5 Receptor, a Novel Target for Diabesity 103
Modulators of the kynurenine pathway of triptophan metabolism. Synthesis and preliminary biological evaluation of (S)-4-(ethylsulfonyl)benzoylalanine, the first potent and selective kynurenine aminotransferse II (KAT II) inhibitor 103
Avicholic acid: a lead compound from birds on the route to potent TGR5 modulators 103
A new aminoacid derivative of ursodeoxycholate, N-L-glutamyl-UDCA (UDCA-glu) to release selectively UDCA in the rat colon. 103
Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage 102
Indium triflate catalyzed reaction of diisopropyl diazomethylphophonate with imines as a new approach to cis- and trans-aziridine-2-phosphonates 102
3,4-Cyclopropyl-glutamates as N-Methyl-D-aspartate Receptor Ligands 102
Exploiting Chemical Toolboxes for the Expedited Generation of Tetracyclic Quinolines as a Novel Class of PXR Agonists 102
Administration of 3 alpha-6 alpha-dihydroxy-7a alpha-fluoro-5 beta-cholanoate (UPF-680) in chronic cholestasis induced by 17 alpha-ethynyl-estradiol (17 alpha EE) in rats. 101
'On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo’ 100
BILE-ACIDS WITH A CYCLOPROPYL-CONTAINING SIDE-CHAIN .4. PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES OF THE 4 DIASTEREOISOMERS OF 3-ALPHA,7-BETA-DIHYDROXY-22,23-METHYLENE-5-BETA-CHOLAN-24-OIC ACID 100
Novel PARP Inhibitors: Synthesis and Molecular Modeling Studies 99
New one-pot synthesis of pyrazole-5-carboxylates by 1,3-dipole cycloadditions of ethyl diazoacetate with α-methylene carbonyl compunds 99
C3-Fullero-tris-methanodicarboxylic acid protects epithelial cells from radiation induced anoikia by influencing cell adhesion ability 99
An efficient procedure for the regiospecific preparation of D-homo-steroid derivatives. 99
Preparation and Physicochemical Properties of Natural (23R)-3alpha,7alpha,23- and (23R)-3alpha,12alpha,23-Trihydroxylated Bile Acids and Their (23S)-Epimers 99
Application of Untargeted and Targeted Metabolomics to the Study of Liver Disease Caused by a Deficiency in HSD3B7-diagnosis and Response to Therapy 99
Sequence variants in kynurenine aminotransferase II (KAT II) orthologs determine different potencies of the inhibitor S-ESBA 99
Bile Acids Signal via TGR5 to Activate Intestinal Stem Cells and Epithelial Regeneration 99
Binding modes of noncompetitive AMPA Antagonists: A computational approach 98
Definition of a pharmacophore for the metabotropic glutamate receptors negatively linked to adenylyl cyclase 98
S-Trityl-(R)-cysteine, a powerful chiral selector for the analytical and preparative ligand-exchange chromatography of amino acids 97
S-(+)-2-(3'carboxy-bicyclo[1.1.1]pentyl)glycine, a structurally new group I metabotropic glutamate receptor antagonist 97
Synthesis, Molecular Modeling and Preliminary Biological Evaluation of 1-Amino-3-Phospono-3-Cyclopentene-1-Carboxylic acid and 1-Amino-3-Phosphono-2-Cyclopentene-1-Carboxylic acid, Two Novel Agonists of Metabotropic Glutamate Receptors of Group III 97
Antagonist Pharmacology of Metabotropic Glutamate Receptors Coupled to Phospholipase D Activation in Adult Rat Hippocampus: Focus on (2R,1’S,2’R,3’S)-2-(2’-Carboxy-3’-phenylcyclopropyl)glycine (PCCG-13) Versus 3,5-Dihydroxyphenylglycine 97
A new synthesis of carboxyterfenadine (fexofenadine) and its bioisoteric tetrazole analogs 97
Evaluation of the enantiomeric selectivity in the Chiral Ligand-Exchange Chromatography of amino acids by a computational model 97
Chiral ligand-exchange separation and resolution ofextremely rigid glutamate analogs: 1-aminospiro[2.2]pentyl-1,4-dicarboxylicacids. 97
C-3-fullero-tris-methanodicarboxylic acid protects cerebellar granule cells from apoptosis 97
BILE-ACIDS WITH A CYCLOPROPYL-CONTAINING SIDE-CHAIN .3. SEPARATION, IDENTIFICATION, AND PROPERTIES OF ALL 4 STEREOISOMERS OF 3-ALPHA,7-BETA-DIHYDROXY-22,23-METHYLENE-5-BETA-CHOLAN-24-OIC ACID 97
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy. 97
Development of 3α, 7α-dihydroxy-6α-ethyl-24-nor-5β-cholan-23-sulfate sodium salt (INT-767): Process optimization, synthesis and characterization of metabolites 96
Novel stereoselective synthesis and chromatographic evaluation of E-guggulsterone 96
Back door modulation of the farnesoid X receptor: design, synthesis, and biological evaluation of a series of side chain modified chenodeoxycholic acid derivatives. 96
Modeling of Poly(ADP-ribose)polymerase (PARP) Inhibitors. Docking of Ligands and QSAR 95
Poly(ADP-ribose)-Polimerase-Catalyzed Hydrolysis of NAD+: QM/MM Simulation of the Enzyme Reaction 94
Rat Brain Guanosine Binding Site:Biological Studies and Pseudo Receptor Construction 94
‘Exploring the metal-catalyzed reaction of furans with alkyl α-diazomethanesulfonate and α-diazomethanephosphonate: Synthesis of ω-acyl- substituted sulfono- and phosphonobutadienes’ 93
Chiral ligand-exchange separation and resolution of extremely rigid glutamate analogues: 1-aminospiro[2.2]pentyl-1,4-dicarboxylic acids 93
Dissecting the allosteric FXR modulation: A chemical biology approach using guggulsterone as a chemical tool 93
Rat brain guanosine binding site. Biological studies and pseudo-Receptor construction 92
Discovery and characterization of novel potent PARP-1 inhibitors endowed with neuroprotective properties: From TIQ-A to HYDAMTIQ 92
Type 2 Metabotropic Glutamate (mGlu) Receptors Tonically Inhibit Transmitter Release in rat caudate Nucleus: In Vivo studies with (2S,1’S,2’S,3’R)-phenylcarboxycyclopropylglycine, a New Potent and Selective Antagonist 92
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy 92
Insights into the binding mode and mechanism of action of some atypical retinoids as ligands of the small heterodimer partner (SHP) 92
Molecular docking and spatial coarse graining simulations as tools to investigate substrate recognition, enhancer binding and conformational transitions in indoleamine-2,3-dioxygenase (IDO). 91
Totale 11.286
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Categoria #
all - tutte 114.787
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 114.787
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021431 0 0 0 0 0 0 0 0 0 0 0 431
2021/20222.442 59 431 38 194 80 24 17 883 22 55 288 351
2022/20234.047 339 482 49 295 424 477 8 186 1.593 10 144 40
2023/20241.511 95 201 97 20 12 17 260 37 221 51 223 277
2024/20254.029 81 402 178 176 522 139 106 287 865 247 636 390
2025/20268.249 670 715 388 964 988 801 1.516 373 870 696 191 77
Totale 26.238