IRIS - Res&Arch Institutional Research Information System - Research & Archive

PELLICCIARI, Roberto
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 8.462
EU - Europa 6.643
AS - Asia 5.497
SA - Sud America 875
AF - Africa 89
Continente sconosciuto - Info sul continente non disponibili 12
OC - Oceania 7
Totale 21.585
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 8.314
SG - Singapore 2.407
UA - Ucraina 1.740
IE - Irlanda 1.222
SE - Svezia 857
HK - Hong Kong 842
CN - Cina 788
BR - Brasile 755
RU - Federazione Russa 724
VN - Vietnam 606
IT - Italia 524
DE - Germania 501
FI - Finlandia 401
KR - Corea 304
GB - Regno Unito 208
TR - Turchia 194
CA - Canada 77
FR - Francia 76
IN - India 71
JP - Giappone 67
PL - Polonia 61
CH - Svizzera 60
AR - Argentina 51
BE - Belgio 50
NL - Olanda 48
MX - Messico 46
AT - Austria 36
ZA - Sudafrica 33
BD - Bangladesh 32
CZ - Repubblica Ceca 32
UZ - Uzbekistan 32
ES - Italia 31
LB - Libano 21
PK - Pakistan 19
EC - Ecuador 17
IQ - Iraq 17
LT - Lituania 17
AE - Emirati Arabi Uniti 13
EG - Egitto 13
GR - Grecia 13
MA - Marocco 13
CO - Colombia 12
EU - Europa 12
ID - Indonesia 11
IL - Israele 11
BG - Bulgaria 10
JM - Giamaica 9
VE - Venezuela 9
SA - Arabia Saudita 8
CL - Cile 7
PY - Paraguay 7
UY - Uruguay 7
JO - Giordania 6
OM - Oman 6
PS - Palestinian Territory 6
AU - Australia 5
AZ - Azerbaigian 5
DZ - Algeria 5
NO - Norvegia 5
NP - Nepal 5
PE - Perù 5
DK - Danimarca 4
RS - Serbia 4
TW - Taiwan 4
BB - Barbados 3
BO - Bolivia 3
GE - Georgia 3
MU - Mauritius 3
NG - Nigeria 3
PT - Portogallo 3
RO - Romania 3
SK - Slovacchia (Repubblica Slovacca) 3
AL - Albania 2
AM - Armenia 2
BW - Botswana 2
CG - Congo 2
DM - Dominica 2
ET - Etiopia 2
GT - Guatemala 2
HR - Croazia 2
IR - Iran 2
KE - Kenya 2
KW - Kuwait 2
KZ - Kazakistan 2
MD - Moldavia 2
NZ - Nuova Zelanda 2
PA - Panama 2
PH - Filippine 2
PR - Porto Rico 2
SN - Senegal 2
TH - Thailandia 2
TN - Tunisia 2
AF - Afghanistan, Repubblica islamica di 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
BJ - Benin 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
Totale 21.568
Salva come PNG Salva come JPEG
Città #
Singapore 1.423
Dublin 1.221
Chandler 1.206
Jacksonville 1.002
Hong Kong 840
San Mateo 705
Boardman 453
Dong Ket 385
Santa Clara 375
Ashburn 370
Medford 313
Princeton 311
Seoul 301
Moscow 254
Wilmington 245
Andover 206
Ann Arbor 193
Beijing 171
Altamura 167
Izmir 163
Perugia 148
Los Angeles 139
Lawrence 131
Des Moines 119
Munich 111
New York 96
Piscataway 95
São Paulo 95
Saint Petersburg 88
Ho Chi Minh City 78
Tokyo 60
Norwalk 58
Woodbridge 56
Helsinki 54
The Dalles 53
Hanoi 50
Brussels 46
Turku 41
Nanjing 38
Warsaw 36
Shanghai 35
Auburn Hills 34
Brooklyn 34
Dallas 34
London 28
San Paolo di Civitate 28
Boston 26
Denver 26
Chicago 25
Johannesburg 25
Montreal 25
Orem 25
Rio de Janeiro 25
Belo Horizonte 24
Chennai 24
Stockholm 22
Columbus 21
Poplar 21
Falls Church 20
Manchester 20
Phoenix 20
Houston 19
Mexico City 19
Toronto 19
Atlanta 18
Brno 18
Redwood City 18
San Francisco 18
Den Haag 16
Rome 15
Tashkent 15
Ankara 14
Hanover 14
Ambler 13
Frankfurt Am Main 13
Seattle 13
Amsterdam 12
Brasília 12
Charlotte 12
Chongqing 12
Mumbai 12
Ottawa 12
Philadelphia 12
Cairo 11
Curitiba 11
Nuremberg 11
Hefei 10
Redmond 10
Campinas 9
Frankfurt am Main 9
Lahore 9
Lausanne 9
Mcallen 9
Misano Adriatico 9
Tianjin 9
Casablanca 8
Changsha 8
Da Nang 8
Dhaka 8
Falkenstein 8
Totale 12.920
Salva come PNG Salva come JPEG
Nome #
2-Amino-4,5-methyleneadipic Acid Compounds for Treatment of CNS Disorders 247
1-AMINOINDAN-1,5-DICARBOXYLIC ACID - A NOVEL ANTAGONIST AT PHOSPHOLIPASE C-LINKED METABOTROPIC GLUTAMATE RECEPTORS 205
AMINO-ACID DERIVATIVES OF 5-ASA AS NOVEL PRODRUGS FOR INTESTINAL DRUG-DELIVERY 136
Asymmetric synthesis of (2R, 1’S, 2’R, 3’S)-2-(2’- Carboxy-3’-phenylcyclopropyl)glicine (PCCG 13), the first selective antagonist of metabotropic glutamate receptors coupled phospholipase D 136
Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor 130
5-ASA-glutamate protects rats from inflammaory bowel disease induced by intracolonic administration of trinitrobenzensulfonic acid. 126
9. The Systems Biology of Transporters – Targeting the Regulatory System for Transporters (FXR/RXR) 120
Avicholic Acid: A Primary Bile Acid from Birds on the Route to Potent and Selective TGR5 Ligands 117
Asymmetric Synthesis of Enantiomerically Pure (2S,1'S,2'S,3'R)-Phenylcarboxycyclopropylglycine (PCCG-4): a Potent and Selective Ligand at Group II Metabotropic Glutamate Receptors 115
(S)-Benzyl-O-Serine (S-BOS), a new chiral selector for ligand-exchange chromatography of amino acids. 114
Adamantyl-substituted retinoid-derived molecules that intercact with the orphan nuclear receptor small heterodimer partner:effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis, and inhibition of SRC homology 2 domain-containing protein tyrosine phosphatase-2 activity 113
(2R,1’S,2’R,3’S)-2-(2’-Carboxy-3’-phenylcyclopropyl)glycine (PCCG-13), the First Potent and Selective Competitive Antagonist of Phospholipase D-Coupled Metabotropic Glutamate Receptors: Asymmetric Synthesis and Preliminary Biological Properties 111
Analisi HPLC/ELSD di Acidi Biliari Amidati: un Approccio Efficace Per Assistere Processi Sintetici a Flusso Continuo 111
A farnesoid X receptor-small heterodimer partner regulatory cascade modulates tissue metallproteinase inhibitor-1 and matrix metallprotease expression in hepatic stellate cells and promotes resolution of liver fibrosis’ 110
Structure of Metal-Carbenoid Intermediates Derived from the Dirhodium(II)Tetracarboxylate Mediated Decomposition of ?-Diazocarbonyl Compounds. An ab initio and DTF Study 107
Towards New Neuroprotective Agents: Design and Synthesis of Thieno[2,3-c]-isoquinolinon-5-one as a Potent PARP-1 Inhibitor. 106
Enantioselective Synthesis of Naturally Occurring trans-4-Hydroxy-S-pipecolic Acid-4-sulfate, a New Potent and Selective NMDA Receptor Agonist 106
Asymmetric synthesis of the four diastereoisomers of a novel non-steroidal farnesoid X receptor (FXR) agonist: Role of the chirality on the biological activity 105
(S)-(-)-alpha,alpha-Di(2-naphthyl)-2-pyrrolidine Methanol, a Useful Tool to Study the Recognition Mechanism in Chiral Ligand-Exchange Chromatography (CLEC) 104
7alfa-OH Epimerisation of Bile Acids via Oxido-reduction with Xanthomonas maltophilia 104
Molecular field analysis and 3D-quantitative structure-activity relationship study (MFA 3D-QSAR) unveil novel features of bile acid recognition at TGR5. 104
Chromatographic separation and evaluation of the lipophilicity by reversed-phase high-performance liquid chromatography of fullerene-C60 derivatives 104
a-Amino-b-carboxymuconate-e-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of de Novo Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis 103
Binding Mode of 6ECDCA, a Potent Bile Acid Agonist of the Farnesoid X Receptor (FXR) 102
Spiro[2.2]pentane as a dyssymetric scaffold for conformationally constrained analogues of glutamic acid: diastereodivergent synthesis of 1-aminospiro[2.2]pentyl-1,4-dicarboxylic acids 102
6a-Ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity. 102
Acidi Biliari Ossidrilati in Catena Laterale 101
An essential role of Farnesoid X-Receptor in regulating intestinal fibrosis in murine model of chronic colitis 101
Discovery and Structure–Activity Relationships of Novel ssDAF-12 Receptor Modulators 100
Design, Synthesis and Preliminay Evaluation of Novel 3’-Substituted Carboxycyclopropylglycines as Antagonists at Group 2 Metabotropic Glutamate Receptors 100
Spiro[2.2]pentane as a Dissymmetric Scaffold for Conformationally Constrained Analogues of Glutamic Acid: Focus on Racemic 1-Aminospiro[2.2]pentyl-1,4-dicarboxylic Acids 100
"*-Diazocarbonyl Chemistry - Target Driven Applications" 99
On the way to selective PARP-2 inhibitors. Design, synthesis, and preliminary evaluation of a series of isoquinolinone derivatives. 99
A new computational model to predict the elution order in the chiral ligand-exchange chromatography (CLEC) of amino acids 99
Novel Potent and Selective Bile Acid Derivatives as TGR5 Agonists: Biological Screening, Structure-Activity Relationships and Molecular Modeling Studies 97
Beyond Bile Acids: Targeting Farnesoid X Receptor (FXR) with Natural and Synthetic Ligands 97
(S)-(-)-a,a-Di(2-naphthyl)-2-pyrrolidine Methanol, a useful tool to study the recognition mechanism in chiral ligand-exchange chromatography (CLEC) 96
1μs Molecular Dynamics Simulations to study the poisoning effect of the PARP-1 full length enzyme 96
Discovery of 6α-Ethyl-23(S)-methyl-cholic Acid (S-EMCA, INT-777) as a Potent and Selective Agonist for the TGR5 Receptor, a Novel Target for Diabesity 95
Metabotropic glutamate receptors: structure and new subtype-selective ligands 95
Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage 95
(2S,1'S, 2'S, 3'R)-2-(2'-carboxy,3'-phenylcyclopropyl)glycine, a potent and selective antagonist of type 2 metabotropic glutamate receptors, 94
Synthesis, Molecular Modeling and Preliminary Biological Evaluation of 1-Amino-3-Phospono-3-Cyclopentene-1-Carboxylic acid and 1-Amino-3-Phosphono-2-Cyclopentene-1-Carboxylic acid, Two Novel Agonists of Metabotropic Glutamate Receptors of Group III 94
Side-chain Modified Bile Acids: Chromatographic Separation of 23-Methyl Epimers 94
Alternative strategies for targeting mouse double minute 2 activity with small molecules: novel patents on the horizon? 94
23-METHYL-3-ALPHA,7-BETA-DIHYDROXY-5-BETA-CHOLAN-24-OIC ACID - DOSE-RESPONSE STUDY OF BILIARY-SECRETION IN RAT 94
Targeting the FXR nuclear receptor through a virtual screening approach 94
Design and synthesis of 4H-thieno[2,3-c]isoquinolin-5-one derivatives as potent PARP-1 inhibitors, on route of new antiischemic agents 94
Side chain modified HDCA derivatives: synthesis, CMC determination and molecular modelling studies. 94
Synthesis, molecular modeling studies, and preliminary pharmacological characterization of all possible 2-(2'-sulfonocyclopropyl)glycine stereoisomers as conformationally constrained L-homocysteic acid analogs. 93
BF3•Et2O-Induced Decomposition of Ethyl 2-Diazo-3-hydroxy-3,3-diarylpropanoates in Acetonitrile: A Novel Approach to 2,3-Diaryl β-Enamino Ester Derivatives 93
Insights into Phenylalanine Derivatives Recognition of VLA-4 Integrin: from a Pharmacophoric Study to 3D-QSAR and Molecular Docking Analyses 92
Administration of 3 alpha-6 alpha-dihydroxy-7a alpha-fluoro-5 beta-cholanoate (UPF-680) in chronic cholestasis induced by 17 alpha-ethynyl-estradiol (17 alpha EE) in rats. 92
BF3·Et2O-Promoted Decomposition of Cyclic α-Diazo-β-Hydroxy Ketones: Novel Insights into Mechanistic Aspects 92
Novel PARP Inhibitors: Synthesis and Molecular Modeling Studies 91
Design, Molecular Modeling Studies, Synthesis and Preliminary Evaluation of Novel PARP-1 Inhibitors on the Road of Antiischemic Agents 91
Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication 90
Dirhodium(II)-tetraacetate-Mediated Decomposition of Ethyldiazo- acetate and Ethyldiazomalonate in the Presence of Fullerene. A New Procedure for the Selective Synthesis of [6-6]-Closed Methanofullerenes 90
New one-pot synthesis of pyrazole-5-carboxylates by 1,3-dipole cycloadditions of ethyl diazoacetate with α-methylene carbonyl compunds 90
A new synthesis of carboxyterfenadine (fexofenadine) and its bioisoteric tetrazole analogs 90
Evaluation of the enantiomeric selectivity in the Chiral Ligand-Exchange Chromatography of amino acids by a computational model 90
Indium triflate catalyzed reaction of diisopropyl diazomethylphophonate with imines as a new approach to cis- and trans-aziridine-2-phosphonates 90
An efficient procedure for the regiospecific preparation of D-homo-steroid derivatives. 90
Avicholic acid: a lead compound from birds on the route to potent TGR5 modulators 90
A new aminoacid derivative of ursodeoxycholate, N-L-glutamyl-UDCA (UDCA-glu) to release selectively UDCA in the rat colon. 90
C3-Fullero-tris-methanodicarboxylic acid protects epithelial cells from radiation induced anoikia by influencing cell adhesion ability 89
3,4-Cyclopropyl-glutamates as N-Methyl-D-aspartate Receptor Ligands 89
Sequence variants in kynurenine aminotransferase II (KAT II) orthologs determine different potencies of the inhibitor S-ESBA 89
S-(+)-2-(3'carboxy-bicyclo[1.1.1]pentyl)glycine, a structurally new group I metabotropic glutamate receptor antagonist 88
Chromatographic hydrophobicity index: a high-throughput tool to estimate the critical micellar concentration of bile acids 87
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy. 87
Poly(ADP-ribose)-Polimerase-Catalyzed Hydrolysis of NAD+: QM/MM Simulation of the Enzyme Reaction 86
Rat Brain Guanosine Binding Site:Biological Studies and Pseudo Receptor Construction 86
Modulators of the kynurenine pathway of triptophan metabolism. Synthesis and preliminary biological evaluation of (S)-4-(ethylsulfonyl)benzoylalanine, the first potent and selective kynurenine aminotransferse II (KAT II) inhibitor 86
S-Trityl-(R)-cysteine, a powerful chiral selector for the analytical and preparative ligand-exchange chromatography of amino acids 85
Poly(ADP-ribose)-polymerase-catalyzed hydrolysis of NAD+: QM/MM simulation of the enzyme reaction. ChemMedChem. 2006 May;1(5):533-9. 85
Antagonist Pharmacology of Metabotropic Glutamate Receptors Coupled to Phospholipase D Activation in Adult Rat Hippocampus: Focus on (2R,1’S,2’R,3’S)-2-(2’-Carboxy-3’-phenylcyclopropyl)glycine (PCCG-13) Versus 3,5-Dihydroxyphenylglycine 85
Binding modes of noncompetitive AMPA Antagonists: A computational approach 85
‘Exploring the metal-catalyzed reaction of furans with alkyl α-diazomethanesulfonate and α-diazomethanephosphonate: Synthesis of ω-acyl- substituted sulfono- and phosphonobutadienes’ 84
Metabotropic Glutamate Receptors: A Structural View Point 83
Synthesis, Molecular modeling studies and preliminary pharmacological characterization of all the eight possible 2-(2'sulfonocylcopropyl)glycine stereoisomers, as conformationally constrined L-homocysteic acid analogs 83
Exploiting Chemical Toolboxes for the Expedited Generation of Tetracyclic Quinolines as a Novel Class of PXR Agonists 83
Thermal and Catalytic Reactions of Diazoacetylmetallocenes with [60]fullerene 83
Preparation and Physicochemical Properties of Natural (23R)-3alpha,7alpha,23- and (23R)-3alpha,12alpha,23-Trihydroxylated Bile Acids and Their (23S)-Epimers 82
Application of Untargeted and Targeted Metabolomics to the Study of Liver Disease Caused by a Deficiency in HSD3B7-diagnosis and Response to Therapy 82
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy 81
Chiral ligand-exchange separation and resolution ofextremely rigid glutamate analogs: 1-aminospiro[2.2]pentyl-1,4-dicarboxylicacids. 80
Bile acids: property-activity relationship and molecular modelling studies 80
C-3-fullero-tris-methanodicarboxylic acid protects cerebellar granule cells from apoptosis 80
Synthesis of methano[60]fullerenephosphomic - and Methano[60] fullerenedisphonic Acids 79
Discovery of 3α,7α,11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid (TC-100), a Novel Bile Acid as Potent and Highly Selective FXR Agonist for Enterohepatic Disorders 79
Bile Acids Signal via TGR5 to Activate Intestinal Stem Cells and Epithelial Regeneration 79
'On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo’ 78
Targeting the conformational transitions of MDM2 and MDMX: insights into dissimilarities and similarities of p53 recognition. 78
3,4-Cyclopropyl Glutamates as Conformationally Restricted Agonists of the NMDA Receptor 78
BILE-ACIDS WITH A CYCLOPROPYL-CONTAINING SIDE-CHAIN .4. PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES OF THE 4 DIASTEREOISOMERS OF 3-ALPHA,7-BETA-DIHYDROXY-22,23-METHYLENE-5-BETA-CHOLAN-24-OIC ACID 78
Definition of a pharmacophore for the metabotropic glutamate receptors negatively linked to adenylyl cyclase 78
Type 2 Metabotropic Glutamate (mGlu) Receptors Tonically Inhibit Transmitter Release in rat caudate Nucleus: In Vivo studies with (2S,1’S,2’S,3’R)-phenylcarboxycyclopropylglycine, a New Potent and Selective Antagonist 78
Modeling of Poly(ADP-ribose)polymerase (PARP) Inhibitors. Docking of Ligands and QSAR 77
Highlights at the gate of tryptophan catabolism: a review on the mechanism of activation and regulation of indoleamine 2,3-dioxigenase (IDO), a novel target in cancer disease 77
Totale 9.703
Salva come PNG Salva come JPEG
Categoria #
all - tutte 101.277
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 101.277
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.563 0 0 0 0 0 145 274 3 346 72 292 431
2021/20222.442 59 431 38 194 80 24 17 883 22 55 288 351
2022/20234.047 339 482 49 295 424 477 8 186 1.593 10 144 40
2023/20241.511 95 201 97 20 12 17 260 37 221 51 223 277
2024/20254.029 81 402 178 176 522 139 106 287 865 247 636 390
2025/20264.286 670 715 388 964 988 561 0 0 0 0 0 0
Totale 22.275