IRIS - Res&Arch Institutional Research Information System - Research & Archive

PELLICCIARI, Roberto
 Distribuzione geografica
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Continente #
NA - Nord America 9.582
EU - Europa 7.335
AS - Asia 7.004
SA - Sud America 1.097
AF - Africa 162
Continente sconosciuto - Info sul continente non disponibili 12
OC - Oceania 9
Totale 25.201
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Nazione #
US - Stati Uniti d'America 9.396
SG - Singapore 3.244
UA - Ucraina 1.749
IE - Irlanda 1.222
RU - Federazione Russa 1.010
HK - Hong Kong 898
CN - Cina 883
SE - Svezia 858
BR - Brasile 847
VN - Vietnam 697
IT - Italia 547
DE - Germania 518
FI - Finlandia 406
FR - Francia 373
KR - Corea 304
TR - Turchia 234
GB - Regno Unito 229
IN - India 165
BD - Bangladesh 96
AR - Argentina 86
CA - Canada 81
JP - Giappone 77
PL - Polonia 62
MX - Messico 61
CH - Svizzera 60
IQ - Iraq 58
NL - Olanda 57
CO - Colombia 52
BE - Belgio 50
UZ - Uzbekistan 50
PK - Pakistan 43
ZA - Sudafrica 43
ES - Italia 37
AT - Austria 36
CZ - Repubblica Ceca 33
SA - Arabia Saudita 33
PH - Filippine 31
EC - Ecuador 29
ID - Indonesia 29
VE - Venezuela 28
LB - Libano 24
EG - Egitto 21
JO - Giordania 21
ET - Etiopia 19
LT - Lituania 18
MA - Marocco 17
AE - Emirati Arabi Uniti 16
CL - Cile 15
PY - Paraguay 15
BG - Bulgaria 13
GR - Grecia 13
JM - Giamaica 13
MY - Malesia 13
EU - Europa 12
IL - Israele 12
TN - Tunisia 12
AZ - Azerbaigian 10
DZ - Algeria 9
KE - Kenya 9
OM - Oman 9
PE - Perù 9
NP - Nepal 8
UY - Uruguay 8
AU - Australia 7
PS - Palestinian Territory 7
BO - Bolivia 6
CR - Costa Rica 6
KW - Kuwait 6
KZ - Kazakistan 6
AL - Albania 5
LY - Libia 5
NO - Norvegia 5
PA - Panama 5
PT - Portogallo 5
QA - Qatar 5
RS - Serbia 5
DK - Danimarca 4
GE - Georgia 4
HN - Honduras 4
HR - Croazia 4
NG - Nigeria 4
SN - Senegal 4
TW - Taiwan 4
AM - Armenia 3
BB - Barbados 3
MU - Mauritius 3
RO - Romania 3
SK - Slovacchia (Repubblica Slovacca) 3
TH - Thailandia 3
BA - Bosnia-Erzegovina 2
BW - Botswana 2
BY - Bielorussia 2
CG - Congo 2
CI - Costa d'Avorio 2
DM - Dominica 2
DO - Repubblica Dominicana 2
GH - Ghana 2
GT - Guatemala 2
IR - Iran 2
MD - Moldavia 2
Totale 25.169
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Città #
Singapore 2.169
Dublin 1.221
Chandler 1.206
Jacksonville 1.002
Hong Kong 895
San Jose 772
San Mateo 705
Ashburn 523
Boardman 453
Santa Clara 396
Dong Ket 385
Moscow 374
Medford 313
Princeton 311
Seoul 301
Lauterbourg 288
Wilmington 245
Andover 206
Beijing 194
Ann Arbor 193
Altamura 167
Izmir 166
Perugia 155
Los Angeles 143
Lawrence 131
Des Moines 121
Munich 111
São Paulo 104
Ho Chi Minh City 101
New York 99
Piscataway 95
The Dalles 93
Saint Petersburg 88
Hanoi 70
Tokyo 68
Helsinki 59
Norwalk 58
Woodbridge 56
Orem 49
Brussels 46
Turku 41
Chennai 40
Nanjing 38
Warsaw 36
Dallas 35
Shanghai 35
Auburn Hills 34
Brooklyn 34
London 30
Tashkent 30
Chicago 29
Rio de Janeiro 28
San Paolo di Civitate 28
Boston 27
Manchester 27
Denver 26
Johannesburg 26
Belo Horizonte 25
Montreal 25
Baghdad 23
Phoenix 23
Stockholm 23
Houston 22
Ambler 21
Columbus 21
Poplar 21
Falls Church 20
Mexico City 20
Toronto 20
Addis Ababa 19
Amsterdam 19
Atlanta 19
Ankara 18
Brno 18
Frankfurt am Main 18
Redwood City 18
San Francisco 18
Amman 17
Mumbai 17
New Delhi 17
Rome 17
Den Haag 16
Lahore 16
Medellín 16
Philadelphia 16
Brasília 15
Riyadh 15
Da Nang 14
Dhaka 14
Hanover 14
Nuremberg 14
Ottawa 14
Seattle 14
Curitiba 13
Frankfurt Am Main 13
Cairo 12
Charlotte 12
Chongqing 12
Delhi 12
Casablanca 10
Totale 15.417
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Nome #
2-Amino-4,5-methyleneadipic Acid Compounds for Treatment of CNS Disorders 264
1-AMINOINDAN-1,5-DICARBOXYLIC ACID - A NOVEL ANTAGONIST AT PHOSPHOLIPASE C-LINKED METABOTROPIC GLUTAMATE RECEPTORS 221
Asymmetric synthesis of (2R, 1’S, 2’R, 3’S)-2-(2’- Carboxy-3’-phenylcyclopropyl)glicine (PCCG 13), the first selective antagonist of metabotropic glutamate receptors coupled phospholipase D 176
Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor 156
AMINO-ACID DERIVATIVES OF 5-ASA AS NOVEL PRODRUGS FOR INTESTINAL DRUG-DELIVERY 151
5-ASA-glutamate protects rats from inflammaory bowel disease induced by intracolonic administration of trinitrobenzensulfonic acid. 145
Molecular field analysis and 3D-quantitative structure-activity relationship study (MFA 3D-QSAR) unveil novel features of bile acid recognition at TGR5. 139
9. The Systems Biology of Transporters – Targeting the Regulatory System for Transporters (FXR/RXR) 139
Avicholic Acid: A Primary Bile Acid from Birds on the Route to Potent and Selective TGR5 Ligands 134
(S)-Benzyl-O-Serine (S-BOS), a new chiral selector for ligand-exchange chromatography of amino acids. 133
Adamantyl-substituted retinoid-derived molecules that intercact with the orphan nuclear receptor small heterodimer partner:effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis, and inhibition of SRC homology 2 domain-containing protein tyrosine phosphatase-2 activity 131
A farnesoid X receptor-small heterodimer partner regulatory cascade modulates tissue metallproteinase inhibitor-1 and matrix metallprotease expression in hepatic stellate cells and promotes resolution of liver fibrosis’ 130
Asymmetric Synthesis of Enantiomerically Pure (2S,1'S,2'S,3'R)-Phenylcarboxycyclopropylglycine (PCCG-4): a Potent and Selective Ligand at Group II Metabotropic Glutamate Receptors 124
6a-Ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity. 124
Enantioselective Synthesis of Naturally Occurring trans-4-Hydroxy-S-pipecolic Acid-4-sulfate, a New Potent and Selective NMDA Receptor Agonist 124
(2R,1’S,2’R,3’S)-2-(2’-Carboxy-3’-phenylcyclopropyl)glycine (PCCG-13), the First Potent and Selective Competitive Antagonist of Phospholipase D-Coupled Metabotropic Glutamate Receptors: Asymmetric Synthesis and Preliminary Biological Properties 123
(S)-(-)-alpha,alpha-Di(2-naphthyl)-2-pyrrolidine Methanol, a Useful Tool to Study the Recognition Mechanism in Chiral Ligand-Exchange Chromatography (CLEC) 122
Binding Mode of 6ECDCA, a Potent Bile Acid Agonist of the Farnesoid X Receptor (FXR) 120
Alternative strategies for targeting mouse double minute 2 activity with small molecules: novel patents on the horizon? 120
23-METHYL-3-ALPHA,7-BETA-DIHYDROXY-5-BETA-CHOLAN-24-OIC ACID - DOSE-RESPONSE STUDY OF BILIARY-SECRETION IN RAT 119
(S)-(-)-a,a-Di(2-naphthyl)-2-pyrrolidine Methanol, a useful tool to study the recognition mechanism in chiral ligand-exchange chromatography (CLEC) 119
Analisi HPLC/ELSD di Acidi Biliari Amidati: un Approccio Efficace Per Assistere Processi Sintetici a Flusso Continuo 119
Spiro[2.2]pentane as a Dissymmetric Scaffold for Conformationally Constrained Analogues of Glutamic Acid: Focus on Racemic 1-Aminospiro[2.2]pentyl-1,4-dicarboxylic Acids 118
Asymmetric synthesis of the four diastereoisomers of a novel non-steroidal farnesoid X receptor (FXR) agonist: Role of the chirality on the biological activity 118
a-Amino-b-carboxymuconate-e-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of de Novo Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis 118
Structure of Metal-Carbenoid Intermediates Derived from the Dirhodium(II)Tetracarboxylate Mediated Decomposition of ?-Diazocarbonyl Compounds. An ab initio and DTF Study 117
7alfa-OH Epimerisation of Bile Acids via Oxido-reduction with Xanthomonas maltophilia 116
Towards New Neuroprotective Agents: Design and Synthesis of Thieno[2,3-c]-isoquinolinon-5-one as a Potent PARP-1 Inhibitor. 116
Side chain modified HDCA derivatives: synthesis, CMC determination and molecular modelling studies. 116
Discovery and Structure–Activity Relationships of Novel ssDAF-12 Receptor Modulators 115
Spiro[2.2]pentane as a dyssymetric scaffold for conformationally constrained analogues of glutamic acid: diastereodivergent synthesis of 1-aminospiro[2.2]pentyl-1,4-dicarboxylic acids 114
An essential role of Farnesoid X-Receptor in regulating intestinal fibrosis in murine model of chronic colitis 114
Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication 113
BF3•Et2O-Induced Decomposition of Ethyl 2-Diazo-3-hydroxy-3,3-diarylpropanoates in Acetonitrile: A Novel Approach to 2,3-Diaryl β-Enamino Ester Derivatives 113
A new computational model to predict the elution order in the chiral ligand-exchange chromatography (CLEC) of amino acids 113
Novel Potent and Selective Bile Acid Derivatives as TGR5 Agonists: Biological Screening, Structure-Activity Relationships and Molecular Modeling Studies 112
1μs Molecular Dynamics Simulations to study the poisoning effect of the PARP-1 full length enzyme 112
Insights into Phenylalanine Derivatives Recognition of VLA-4 Integrin: from a Pharmacophoric Study to 3D-QSAR and Molecular Docking Analyses 111
Design, Synthesis and Preliminay Evaluation of Novel 3’-Substituted Carboxycyclopropylglycines as Antagonists at Group 2 Metabotropic Glutamate Receptors 111
Chromatographic separation and evaluation of the lipophilicity by reversed-phase high-performance liquid chromatography of fullerene-C60 derivatives 111
"*-Diazocarbonyl Chemistry - Target Driven Applications" 110
BF3·Et2O-Promoted Decomposition of Cyclic α-Diazo-β-Hydroxy Ketones: Novel Insights into Mechanistic Aspects 110
(2S,1'S, 2'S, 3'R)-2-(2'-carboxy,3'-phenylcyclopropyl)glycine, a potent and selective antagonist of type 2 metabotropic glutamate receptors, 109
Targeting the FXR nuclear receptor through a virtual screening approach 109
Metabotropic glutamate receptors: structure and new subtype-selective ligands 108
Acidi Biliari Ossidrilati in Catena Laterale 108
Beyond Bile Acids: Targeting Farnesoid X Receptor (FXR) with Natural and Synthetic Ligands 108
Synthesis, molecular modeling studies, and preliminary pharmacological characterization of all possible 2-(2'-sulfonocyclopropyl)glycine stereoisomers as conformationally constrained L-homocysteic acid analogs. 106
On the way to selective PARP-2 inhibitors. Design, synthesis, and preliminary evaluation of a series of isoquinolinone derivatives. 106
Design and synthesis of 4H-thieno[2,3-c]isoquinolin-5-one derivatives as potent PARP-1 inhibitors, on route of new antiischemic agents 105
Side-chain Modified Bile Acids: Chromatographic Separation of 23-Methyl Epimers 104
Design, Molecular Modeling Studies, Synthesis and Preliminary Evaluation of Novel PARP-1 Inhibitors on the Road of Antiischemic Agents 104
Dirhodium(II)-tetraacetate-Mediated Decomposition of Ethyldiazo- acetate and Ethyldiazomalonate in the Presence of Fullerene. A New Procedure for the Selective Synthesis of [6-6]-Closed Methanofullerenes 103
Discovery of 6α-Ethyl-23(S)-methyl-cholic Acid (S-EMCA, INT-777) as a Potent and Selective Agonist for the TGR5 Receptor, a Novel Target for Diabesity 103
Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage 102
Chromatographic hydrophobicity index: a high-throughput tool to estimate the critical micellar concentration of bile acids 102
Indium triflate catalyzed reaction of diisopropyl diazomethylphophonate with imines as a new approach to cis- and trans-aziridine-2-phosphonates 101
Avicholic acid: a lead compound from birds on the route to potent TGR5 modulators 101
Administration of 3 alpha-6 alpha-dihydroxy-7a alpha-fluoro-5 beta-cholanoate (UPF-680) in chronic cholestasis induced by 17 alpha-ethynyl-estradiol (17 alpha EE) in rats. 101
A new aminoacid derivative of ursodeoxycholate, N-L-glutamyl-UDCA (UDCA-glu) to release selectively UDCA in the rat colon. 101
Exploiting Chemical Toolboxes for the Expedited Generation of Tetracyclic Quinolines as a Novel Class of PXR Agonists 101
Novel PARP Inhibitors: Synthesis and Molecular Modeling Studies 99
'On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo’ 99
New one-pot synthesis of pyrazole-5-carboxylates by 1,3-dipole cycloadditions of ethyl diazoacetate with α-methylene carbonyl compunds 99
3,4-Cyclopropyl-glutamates as N-Methyl-D-aspartate Receptor Ligands 99
An efficient procedure for the regiospecific preparation of D-homo-steroid derivatives. 99
C3-Fullero-tris-methanodicarboxylic acid protects epithelial cells from radiation induced anoikia by influencing cell adhesion ability 98
Modulators of the kynurenine pathway of triptophan metabolism. Synthesis and preliminary biological evaluation of (S)-4-(ethylsulfonyl)benzoylalanine, the first potent and selective kynurenine aminotransferse II (KAT II) inhibitor 98
BILE-ACIDS WITH A CYCLOPROPYL-CONTAINING SIDE-CHAIN .4. PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES OF THE 4 DIASTEREOISOMERS OF 3-ALPHA,7-BETA-DIHYDROXY-22,23-METHYLENE-5-BETA-CHOLAN-24-OIC ACID 98
Definition of a pharmacophore for the metabotropic glutamate receptors negatively linked to adenylyl cyclase 98
Application of Untargeted and Targeted Metabolomics to the Study of Liver Disease Caused by a Deficiency in HSD3B7-diagnosis and Response to Therapy 98
Sequence variants in kynurenine aminotransferase II (KAT II) orthologs determine different potencies of the inhibitor S-ESBA 98
Synthesis, Molecular Modeling and Preliminary Biological Evaluation of 1-Amino-3-Phospono-3-Cyclopentene-1-Carboxylic acid and 1-Amino-3-Phosphono-2-Cyclopentene-1-Carboxylic acid, Two Novel Agonists of Metabotropic Glutamate Receptors of Group III 97
Evaluation of the enantiomeric selectivity in the Chiral Ligand-Exchange Chromatography of amino acids by a computational model 97
Binding modes of noncompetitive AMPA Antagonists: A computational approach 97
BILE-ACIDS WITH A CYCLOPROPYL-CONTAINING SIDE-CHAIN .3. SEPARATION, IDENTIFICATION, AND PROPERTIES OF ALL 4 STEREOISOMERS OF 3-ALPHA,7-BETA-DIHYDROXY-22,23-METHYLENE-5-BETA-CHOLAN-24-OIC ACID 97
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy. 97
Bile Acids Signal via TGR5 to Activate Intestinal Stem Cells and Epithelial Regeneration 97
Development of 3α, 7α-dihydroxy-6α-ethyl-24-nor-5β-cholan-23-sulfate sodium salt (INT-767): Process optimization, synthesis and characterization of metabolites 96
S-Trityl-(R)-cysteine, a powerful chiral selector for the analytical and preparative ligand-exchange chromatography of amino acids 96
S-(+)-2-(3'carboxy-bicyclo[1.1.1]pentyl)glycine, a structurally new group I metabotropic glutamate receptor antagonist 96
C-3-fullero-tris-methanodicarboxylic acid protects cerebellar granule cells from apoptosis 96
Preparation and Physicochemical Properties of Natural (23R)-3alpha,7alpha,23- and (23R)-3alpha,12alpha,23-Trihydroxylated Bile Acids and Their (23S)-Epimers 96
Modeling of Poly(ADP-ribose)polymerase (PARP) Inhibitors. Docking of Ligands and QSAR 95
A new synthesis of carboxyterfenadine (fexofenadine) and its bioisoteric tetrazole analogs 95
Back door modulation of the farnesoid X receptor: design, synthesis, and biological evaluation of a series of side chain modified chenodeoxycholic acid derivatives. 95
Rat Brain Guanosine Binding Site:Biological Studies and Pseudo Receptor Construction 94
Chiral ligand-exchange separation and resolution ofextremely rigid glutamate analogs: 1-aminospiro[2.2]pentyl-1,4-dicarboxylicacids. 94
Poly(ADP-ribose)-Polimerase-Catalyzed Hydrolysis of NAD+: QM/MM Simulation of the Enzyme Reaction 93
‘Exploring the metal-catalyzed reaction of furans with alkyl α-diazomethanesulfonate and α-diazomethanephosphonate: Synthesis of ω-acyl- substituted sulfono- and phosphonobutadienes’ 93
Antagonist Pharmacology of Metabotropic Glutamate Receptors Coupled to Phospholipase D Activation in Adult Rat Hippocampus: Focus on (2R,1’S,2’R,3’S)-2-(2’-Carboxy-3’-phenylcyclopropyl)glycine (PCCG-13) Versus 3,5-Dihydroxyphenylglycine 93
Novel stereoselective synthesis and chromatographic evaluation of E-guggulsterone 93
Dissecting the allosteric FXR modulation: A chemical biology approach using guggulsterone as a chemical tool 93
Rat brain guanosine binding site. Biological studies and pseudo-Receptor construction 92
Chiral ligand-exchange separation and resolution of extremely rigid glutamate analogues: 1-aminospiro[2.2]pentyl-1,4-dicarboxylic acids 92
Discovery and characterization of novel potent PARP-1 inhibitors endowed with neuroprotective properties: From TIQ-A to HYDAMTIQ 92
Type 2 Metabotropic Glutamate (mGlu) Receptors Tonically Inhibit Transmitter Release in rat caudate Nucleus: In Vivo studies with (2S,1’S,2’S,3’R)-phenylcarboxycyclopropylglycine, a New Potent and Selective Antagonist 92
Chromatographic evaluation of the 25-(R,S)-methyl-bishomo-hyodeoxycholic acid epimers 91
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy 91
Insights into the binding mode and mechanism of action of some atypical retinoids as ligands of the small heterodimer partner (SHP) 91
Totale 11.117
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Categoria #
all - tutte 108.693
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 108.693
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021795 0 0 0 0 0 0 0 0 0 72 292 431
2021/20222.442 59 431 38 194 80 24 17 883 22 55 288 351
2022/20234.047 339 482 49 295 424 477 8 186 1.593 10 144 40
2023/20241.511 95 201 97 20 12 17 260 37 221 51 223 277
2024/20254.029 81 402 178 176 522 139 106 287 865 247 636 390
2025/20267.903 670 715 388 964 988 801 1.516 373 870 618 0 0
Totale 25.892