IRIS - Res&Arch Institutional Research Information System - Research & Archive

TANCINI, Brunella
 Distribuzione geografica
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Continente #
NA - Nord America 3.299
EU - Europa 2.605
AS - Asia 2.150
SA - Sud America 396
AF - Africa 36
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 3
Totale 8.493
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Nazione #
US - Stati Uniti d'America 3.243
SG - Singapore 921
UA - Ucraina 541
IE - Irlanda 493
HK - Hong Kong 377
IT - Italia 341
CN - Cina 332
BR - Brasile 328
RU - Federazione Russa 264
SE - Svezia 263
VN - Vietnam 233
DE - Germania 209
FI - Finlandia 152
GB - Regno Unito 109
KR - Corea 108
TR - Turchia 56
FR - Francia 53
PL - Polonia 33
NL - Olanda 32
AR - Argentina 29
CA - Canada 27
BE - Belgio 26
AT - Austria 24
MX - Messico 23
IN - India 20
ZA - Sudafrica 19
BD - Bangladesh 18
CH - Svizzera 16
JP - Giappone 16
UZ - Uzbekistan 14
ES - Italia 13
EC - Ecuador 10
LT - Lituania 10
CO - Colombia 9
MY - Malesia 7
RO - Romania 7
CZ - Repubblica Ceca 6
ID - Indonesia 6
LB - Libano 6
PY - Paraguay 6
VE - Venezuela 6
AE - Emirati Arabi Uniti 5
AZ - Azerbaigian 5
MA - Marocco 5
IR - Iran 4
PK - Pakistan 4
AU - Australia 3
DK - Danimarca 3
IL - Israele 3
IQ - Iraq 3
UY - Uruguay 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BA - Bosnia-Erzegovina 2
CL - Cile 2
DZ - Algeria 2
EG - Egitto 2
EU - Europa 2
HU - Ungheria 2
MD - Moldavia 2
ML - Mali 2
NP - Nepal 2
PE - Perù 2
PH - Filippine 2
TN - Tunisia 2
BH - Bahrain 1
BO - Bolivia 1
BS - Bahamas 1
CI - Costa d'Avorio 1
CY - Cipro 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
GD - Grenada 1
GT - Guatemala 1
HN - Honduras 1
HR - Croazia 1
JO - Giordania 1
KE - Kenya 1
KZ - Kazakistan 1
LV - Lettonia 1
NG - Nigeria 1
OM - Oman 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
TT - Trinidad e Tobago 1
TW - Taiwan 1
YE - Yemen 1
Totale 8.493
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Città #
Singapore 604
Chandler 565
Dublin 493
Hong Kong 375
Jacksonville 296
San Mateo 238
Boardman 172
Ashburn 170
Santa Clara 126
Perugia 122
Ann Arbor 114
Medford 110
Princeton 110
Seoul 107
Dong Ket 106
Wilmington 91
Beijing 84
Moscow 81
Andover 63
Munich 63
Des Moines 59
Los Angeles 51
Altamura 43
Ho Chi Minh City 43
New York 42
Piscataway 39
Saint Petersburg 35
Helsinki 33
Lawrence 33
Izmir 32
São Paulo 32
Hanoi 28
Brussels 25
Shanghai 25
Woodbridge 23
Philadelphia 21
Warsaw 21
Council Bluffs 19
Norwalk 19
Johannesburg 16
Tokyo 16
Amsterdam 15
Atlanta 15
The Dalles 15
Auburn Hills 14
Frankfurt am Main 14
Rome 14
Turku 14
Chicago 13
Dallas 13
Denver 13
Falkenstein 13
Milan 13
Poplar 13
San Francisco 13
Belo Horizonte 12
Brooklyn 12
Montreal 12
Nuremberg 12
Porto Alegre 12
Redmond 12
Rio de Janeiro 12
Falls Church 11
Seattle 11
Ankara 10
Boston 10
Florence 10
London 10
San Paolo di Civitate 10
Mexico City 9
Dronten 8
San Diego 8
Toronto 8
Çankaya 8
Bologna 7
Chennai 7
Columbus 7
Guarulhos 7
Haiphong 7
Houston 7
Kuala Lumpur 7
Stockholm 7
Vienna 7
Brasília 6
Curitiba 6
Guangzhou 6
Manchester 6
Shijiazhuang 6
Aracaju 5
Baku 5
Biên Hòa 5
Campinas 5
Den Haag 5
Dhaka 5
Recife 5
Salvador 5
Zhengzhou 5
Bogotá 4
Changsha 4
Isfahan 4
Totale 5.284
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Nome #
FORMULAZIONE E CARATTERIZZAZIONE DI NUOVI TIPI DI NANOPARTICELLE PER STRATEGIE DI “DRUG DELIVERY” A LIVELLO CEREBRALE 139
Identification and characterization of mature beta-hexosaminidases associated with human placenta lysosomal membrane 125
Adenoviral and AAV vectors for an efficient intracerebral gene transfer in the Sandhoff mouse model 119
Absence of metabolic cross-correction in tay-sachs cells: implication in gene therapy 114
In vivo HSV-1 T0Ahex gene transfer strategy for Tay-Sachs disease provides a wide distribution of B-Hexosaminidase A and restores the GM2 ganglioside metabolims in the brain animal model 112
Bicistronic lentiviral vector corrects beta-hexosaminidase deficiency in transduced and cross-corrected human Sandhoff fibroblasts. 111
beta-hexosaminidase over-expression affects glycosphingolipid metabolism in mammalian cells-52° Congresso SIB 109
Methods to Discriminate the Distribution of Acidic Glycohydrolases Between the Endosomal–Lysosomal Systems and the Plasma MembraneEndosome Signaling Part A 108
Effect of Curcumin on Protein Damage Induced by Rotenone in Dopaminergic PC12 Cells 107
Recruitment of beta-hexosaminidase activity on plasma membrane and human T-cell activation-52° Congresso SIB 102
Absence of metabolic cross-correction in Tay-Sachs cells: implication in gene therapy 101
A direct gene transfer strategy via brain internal capsule reverses the biochemical defect in Tay-Sachs disease 101
Abnormal cortical lysosomal β-hexosaminidase and β-galactosidase activity at post-synaptic sites during Alzheimer's disease progression 99
Assessment of safety and efficiency of nitrogen organic fertilizers from animal-based Protein Hydrolysates - a laboratory multidisciplinary approach 98
Extending lifespan through autophagy stimulation: a future perspective 98
Bicistronic lentiviral vector corrects beta-hexosaminidase deficiency in transduced and cross-corrected human Sandhoff fibroblasts. 97
Use of Polylactide-Co-Glycolide-Nanoparticles for Lysosomal Delivery of a Therapeutic Enzyme in Glycogenesis Type II Fibroblasts 97
Restoration of hexosaminidase A activity and GM2 ganglioside metabolism in cells from patients with Tay-Sachs Disease 96
Expression of human a-subunit gene in the central nervous system of the Tay-Sachs animal model 96
An essential arginine residue at the binding site of pig kidney 3,4-dihydroxyphenylalanine decarboxylase. 94
Jurkat T-cell stimulation up-regulates the expression of lysosomal β-hexosaminidase and β-galactosidase and triggers their recruitment to lipid microdomains 94
Acidic glycohydrolases localization and regulation: pathological implication 93
Oncogenic H-Ras Up-Regulates Acid β-Hexosaminidase by a Mechanism Dependent on the Autophagy Regulator TFEB 93
Curcumin Analogue C1 Promotes Hex and Gal Recruitment to the Plasma Membrane via mTORC1-Independent TFEB Activation 93
The Role of Extracellular Vesicles in Viral Infection and Transmission 93
Plasma membrane associated beta-hexosaminidase activity increases during human T-cells activation 92
Alpha and Beta subunits of b-N-acethyl-hexosaminidase are differently regulated during the mammalian brain development: implication for Tay-Sachs disease therapy 92
NANOPARTICLE-DRIVEN DRUG DELIVERY TO THE CNS: COMPARISON OF PLGA AND LIPID-BASED NAOPARTICLES IN MOUSE MODEL OF NEURODEGENERATIVE DISEASES 91
Evaluation of a LC-MS method for everolimus preclinical determination in brain by using [13C2D4]RAD001 internal standard 91
Sistemi di "Drug delivery di B-esosaminidasi nella mallattia di Tay-Sachs 90
Human plasma membrane associated B-hexosaminidase A Hydrolizes GM2 ganglioside 90
Glycohydrolases β-hexosaminidase and β-galactosidase are associated with lipid microdomains of Jurkat T-lymphocytes 90
Identification of plasma membrane associated mature B-hexosaminidase A, active towards GM2 ganglioside, in human fibroblasts 88
Characterization of human lysosomal α-D-mannosidase in leukaemic and non leukaemic cells 88
New perspectives for the diagnosis of Alzheimer's disease. 87
FIBROBLASTS FROM PS1 MUTATED PRE-SYMPTOMATIC SUBJECTS AND ALZHEIMER’S DISEASE PATIENTS SHARE A UNIQUE PROTEIN LEVELS PROFILE. 87
Cells over-expressing Ras show modulation of lysosomal enzymes activity 86
In vivo gene therapy approach using herpes simplex vector for Tay-Sachs disease 83
Effect of potassium metabisulfite in human fibroblast. 82
Processing and transport of B-hexosaminidase in the DAUDI leukaemic cell line 81
Brain-directed gene transfer therapy for Tay-Sachs disease gives rice a wider distribution of the B-Hexosaminidase A 80
Identification and characterization of a fully processed beta-hexosaminidase isoform associated to lysosomal membrane-52° Congresso SIB 80
Human lysosomal α-D-mannosidase regulation in promyelocytic leukaemia cells. 80
Functional metaproteome analysis of microbial populations in enrichment cultures on polycyclic aromatic hydrocarbons 80
Rapamycin-loaded solid lipid nanoparticles for brain targeting 80
Presenilin genes and Alzheimer's disease 79
Cathepsin L increased level upon Ras mutants expression: the role of p38 and p44/42 MAPK signaling pathways 79
Restoration of the GM2 ganglioside metabolism in bone marrow-derived stromal cells from Tay-Sachs disease animal model 79
Effect of pH on potassium metabisulphite biocidic activity against yeast and human cell cultures 79
Transcriptional regulation of glycosphingolipids degrating enzymes 79
Lysosomal Exocytosis, Exosome Release and Secretory Autophagy: The Autophagic- and Endo-Lysosomal Systems Go Extracellular 79
Presenilin genes and Alzheimer's disease 78
Plasma membrane β-galactosidase and β-hexosaminidase are associated to lipid raft of Jurkat T-cell upon raft clustering. 78
Phospholipid fatty acid remodeling and carbonylated protein increase in extracellular vesicles released by airway epithelial cells exposed to cigarette smoke extract 77
Metagenomic and Metaproteomic Characterization of Enrichment Cultures on Polycyclic Aromatic Hydrocarbons 77
Carbon dioxide capture at gas emission site by carbonic anhidrase 77
β-Hexosaminidase over-expression affects lysosomal glycohydrolases expression and glycosphingolipid metabolism in mammalian cells 76
Evidence for altered late endosomal-lysosomal compartment in Sandhoff fibroblasts 75
Potassium metabisulfite treatement alters human fibroblast protein expression pattern. 75
Direct brain gene transfer strategy for Tay-Sachs disease 73
Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. 72
Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization 72
Extracellular vesicles under oxidative stress conditions: Biological properties and physiological roles 72
Plasma membrane associated beta-hexosaminidase: biological significance and regulation 71
TFEB activation promotes the recruitment of lysosomal glycohydrolases β-hexosaminidase and β-galactosidase to the plasma membrane 71
TFEB overexpression promotes the translocation of lysosomal glycohydrolases beta-hexosaminidase and beta-galactosidase to cell surface lipid microdomains 70
Evidence for the regulation of beta-N-acetylhexosaminidase expression during pregnancy in the rat 69
Biocompatible Polymer Nanoparticles for Drug Delivery Applications in Cancer and Neurodegenerative Disorder Therapies 69
Impairment of lysosomal system in neurodegenerative diseases 68
Evidence for the presence of human B-hexosaminidase B as lysosomal membrane associated protein 68
PROMOTER CHARACTERIZATION AND STRUCTURE OF THE GENE ENCODING THE MOUSE LYSOSOMAL -D-MANNOSIDASE 68
Chemical modification of pig kidney 3,4-dihydroxyphenylalanine decarboxylase with diethyl pyrocarbonate. Evidence for an essential histidyl residue. 67
Directed hexa gene transfer therapy for Tay-Sachs disease provides a wide brain distribution of the B-Hexosaminidase a and restores the GM2 ganglioside metabolism 67
Extracellular Vesicles as New Players in Cellular Senescence 67
Glycosphingolipid metabolism is affected by beta-hexosaminidase over-expression in mammalian cells 66
Modified PLGA-NPS able to cross the blood-brain barrier for the delivery of lysosomal enzymes in llysosomal storage disease 66
Identification of lysosomal membrane associated, fully processed beta-hexosaminidase enzyme 65
Derivatized nanoparticle for CSN-target drug delivery 65
Insight into the Role of Extracellular Vesicles in Lysosomal Storage Disorders. 65
Ras mutants specifically regulates lysosomal glycohydrolases activity in different cell models. 64
mTOR Signaling and Neural Stem Cells: The Tuberous Sclerosis Complex Model 64
β-Hexosaminidase α-subunit overexpression affects lipid microdomain glycohydrolases content 63
Proteome characterization of a microbial community response to polycyclic aromatic hydrocarbons exposure. 63
Stereospecificity of sodium borohydride reduction of pig kidney dopa decarboxylase. 62
Solid lipid nanoparticle as a tool to deliver mTOR inhibitors 62
In vivo gene transfer strategy for Tay-Sachs disease restores the GM2 ganglioside in the brain of the animal model 62
Presenilin genes and Alzheimer's Disease 61
Pig kidney dopa decarboxylase: inactivation by iodoacetamide and sequence of the carboxyamidomethylcysteine-containing peptide. 61
Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. 61
Impairment of lysosomal system in neurodegenerative diseases 60
Gene therapy approach for Tay-Sachs Disease 59
Plasma membrane associated beta-hexosaminidase activity during human T-cells activation 57
Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. 57
Everolimus treatment reduces proliferation of TSC1-deficient adult neural stem/progenitor cells and restores their migration capability. 57
Occurrence of an anomalous endocytic compartment in fibroblasts from Sandhoff disease patients 57
Lysosomal exocytosis: The extracellular role of an intracellular organelle 55
Time-resolved extrinsic fluorescence of aromatic-L-amino-acid decarboxylase. 55
Limited tryptic proteolysis of pig kidney 3,4-dihydroxyphenylalanine decarboxylase. 55
Muscle as a putative producer of acid alpha-glucosidase for glycogenosys type ii gene therapy 55
Recruitment of plasma membrane β-galactosidase and β-hexosaminidase in lipid rafts upon T-cell activation 54
Totale 8.009
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Categoria #
all - tutte 39.167
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.167
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021524 0 0 0 0 0 53 78 8 136 32 96 121
2021/2022855 14 160 25 44 22 9 10 289 19 16 94 153
2022/20231.655 122 221 19 137 159 211 6 69 628 5 62 16
2023/2024696 60 64 46 23 5 7 152 9 100 21 108 101
2024/20251.625 27 166 40 114 212 85 68 104 285 75 298 151
2025/20261.810 258 225 193 554 510 70 0 0 0 0 0 0
Totale 8.781