IRIS - Res&Arch Institutional Research Information System - Research & Archive

TANCINI, Brunella
 Distribuzione geografica
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Continente #
NA - Nord America 2.375
EU - Europa 2.046
AS - Asia 656
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 2
AF - Africa 1
Totale 5.083
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Nazione #
US - Stati Uniti d'America 2.371
UA - Ucraina 534
IE - Irlanda 485
IT - Italia 270
SE - Svezia 253
HK - Hong Kong 227
SG - Singapore 143
FI - Finlandia 122
DE - Germania 108
VN - Vietnam 106
CN - Cina 105
RU - Federazione Russa 96
GB - Regno Unito 61
FR - Francia 32
TR - Turchia 32
BE - Belgio 19
NL - Olanda 18
KR - Corea 15
CH - Svizzera 13
UZ - Uzbekistan 11
AT - Austria 9
PL - Polonia 8
MY - Malesia 7
RO - Romania 6
CZ - Repubblica Ceca 4
IR - Iran 4
IN - India 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AU - Australia 2
CA - Canada 2
ES - Italia 2
HU - Ungheria 2
LB - Libano 2
MX - Messico 2
DK - Danimarca 1
EU - Europa 1
HR - Croazia 1
MA - Marocco 1
MD - Moldavia 1
SK - Slovacchia (Repubblica Slovacca) 1
TW - Taiwan 1
Totale 5.083
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Città #
Chandler 565
Dublin 485
Jacksonville 296
San Mateo 236
Hong Kong 226
Ann Arbor 114
Perugia 114
Medford 109
Princeton 109
Dong Ket 106
Singapore 90
Wilmington 90
Andover 63
Des Moines 58
Ashburn 46
Beijing 45
Altamura 43
Saint Petersburg 34
Lawrence 33
Izmir 32
Boardman 29
Shanghai 23
Woodbridge 23
Philadelphia 21
Helsinki 19
Norwalk 19
Brussels 18
Seoul 15
Auburn Hills 14
Los Angeles 12
Redmond 12
Falls Church 11
San Paolo di Civitate 10
Dronten 8
San Diego 8
Seattle 8
Kuala Lumpur 7
Florence 6
Milan 6
New York 6
Den Haag 5
Amsterdam 4
Bologna 4
Chicago 4
Houston 4
Isfahan 4
Redwood City 4
Rome 4
Calarasi 3
Cattolica 3
Desio 3
Frankfurt Am Main 3
Rende 3
Scandicci 3
Sesto Fiorentino 3
Taranto 3
Aci Sant'Antonio 2
Atlanta 2
Brno 2
Castello di Godego 2
Cormeilles-en-Parisis 2
Lappeenranta 2
Lausanne 2
Macerata 2
Mexico City 2
Morwell 2
Moscow 2
Nanjing 2
Padova 2
Pune 2
Reggio Emilia 2
Santiago De Compostela 2
Shenyang 2
Silea 2
Szigetszentmiklos 2
Tappahannock 2
Timisoara 2
Valenzano 2
Vienna 2
Birmingham 1
Bratislava 1
Casalecchio di Reno 1
Chengdu 1
Chisinau 1
Clearwater 1
Copenhagen 1
Edinburgh 1
Esslingen am Neckar 1
Fairfield 1
Falkenstein 1
Groningen 1
Hangzhou 1
Harrow 1
Hebei 1
Jesi 1
Kaohsiung 1
Kiev 1
Lexington 1
Ludwigshafen 1
Montegaldella 1
Totale 3.293
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Nome #
In vivo HSV-1 T0Ahex gene transfer strategy for Tay-Sachs disease provides a wide distribution of B-Hexosaminidase A and restores the GM2 ganglioside metabolims in the brain animal model 90
Identification and characterization of mature beta-hexosaminidases associated with human placenta lysosomal membrane 89
FORMULAZIONE E CARATTERIZZAZIONE DI NUOVI TIPI DI NANOPARTICELLE PER STRATEGIE DI “DRUG DELIVERY” A LIVELLO CEREBRALE 89
Adenoviral and AAV vectors for an efficient intracerebral gene transfer in the Sandhoff mouse model 88
Use of Polylactide-Co-Glycolide-Nanoparticles for Lysosomal Delivery of a Therapeutic Enzyme in Glycogenesis Type II Fibroblasts 78
Restoration of hexosaminidase A activity and GM2 ganglioside metabolism in cells from patients with Tay-Sachs Disease 76
Expression of human a-subunit gene in the central nervous system of the Tay-Sachs animal model 76
Bicistronic lentiviral vector corrects beta-hexosaminidase deficiency in transduced and cross-corrected human Sandhoff fibroblasts. 68
beta-hexosaminidase over-expression affects glycosphingolipid metabolism in mammalian cells-52° Congresso SIB 68
Recruitment of beta-hexosaminidase activity on plasma membrane and human T-cell activation-52° Congresso SIB 68
Absence of metabolic cross-correction in tay-sachs cells: implication in gene therapy 68
Methods to Discriminate the Distribution of Acidic Glycohydrolases Between the Endosomal–Lysosomal Systems and the Plasma MembraneEndosome Signaling Part A 68
Oncogenic H-Ras Up-Regulates Acid β-Hexosaminidase by a Mechanism Dependent on the Autophagy Regulator TFEB 67
Sistemi di "Drug delivery di B-esosaminidasi nella mallattia di Tay-Sachs 65
Assessment of safety and efficiency of nitrogen organic fertilizers from animal-based Protein Hydrolysates - a laboratory multidisciplinary approach 65
Evaluation of a LC-MS method for everolimus preclinical determination in brain by using [13C2D4]RAD001 internal standard 65
A direct gene transfer strategy via brain internal capsule reverses the biochemical defect in Tay-Sachs disease 65
Alpha and Beta subunits of b-N-acethyl-hexosaminidase are differently regulated during the mammalian brain development: implication for Tay-Sachs disease therapy 63
Jurkat T-cell stimulation up-regulates the expression of lysosomal β-hexosaminidase and β-galactosidase and triggers their recruitment to lipid microdomains 62
Presenilin genes and Alzheimer's disease 61
Processing and transport of B-hexosaminidase in the DAUDI leukaemic cell line 61
Plasma membrane associated beta-hexosaminidase activity increases during human T-cells activation 61
Glycohydrolases β-hexosaminidase and β-galactosidase are associated with lipid microdomains of Jurkat T-lymphocytes 61
Acidic glycohydrolases localization and regulation: pathological implication 61
In vivo gene therapy approach using herpes simplex vector for Tay-Sachs disease 60
Absence of metabolic cross-correction in Tay-Sachs cells: implication in gene therapy 60
NANOPARTICLE-DRIVEN DRUG DELIVERY TO THE CNS: COMPARISON OF PLGA AND LIPID-BASED NAOPARTICLES IN MOUSE MODEL OF NEURODEGENERATIVE DISEASES 59
Presenilin genes and Alzheimer's disease 57
Bicistronic lentiviral vector corrects beta-hexosaminidase deficiency in transduced and cross-corrected human Sandhoff fibroblasts. 57
An essential arginine residue at the binding site of pig kidney 3,4-dihydroxyphenylalanine decarboxylase. 57
Effect of Curcumin on Protein Damage Induced by Rotenone in Dopaminergic PC12 Cells 57
Extending lifespan through autophagy stimulation: a future perspective 56
Human plasma membrane associated B-hexosaminidase A Hydrolizes GM2 ganglioside 55
Plasma membrane β-galactosidase and β-hexosaminidase are associated to lipid raft of Jurkat T-cell upon raft clustering. 55
β-Hexosaminidase over-expression affects lysosomal glycohydrolases expression and glycosphingolipid metabolism in mammalian cells 54
Brain-directed gene transfer therapy for Tay-Sachs disease gives rice a wider distribution of the B-Hexosaminidase A 53
TFEB activation promotes the recruitment of lysosomal glycohydrolases β-hexosaminidase and β-galactosidase to the plasma membrane 53
Abnormal cortical lysosomal β-hexosaminidase and β-galactosidase activity at post-synaptic sites during Alzheimer's disease progression 53
Metagenomic and Metaproteomic Characterization of Enrichment Cultures on Polycyclic Aromatic Hydrocarbons 52
Identification and characterization of a fully processed beta-hexosaminidase isoform associated to lysosomal membrane-52° Congresso SIB 51
Human lysosomal α-D-mannosidase regulation in promyelocytic leukaemia cells. 51
Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. 51
The Role of Extracellular Vesicles in Viral Infection and Transmission 51
FIBROBLASTS FROM PS1 MUTATED PRE-SYMPTOMATIC SUBJECTS AND ALZHEIMER’S DISEASE PATIENTS SHARE A UNIQUE PROTEIN LEVELS PROFILE. 50
Cells over-expressing Ras show modulation of lysosomal enzymes activity 50
Characterization of human lysosomal α-D-mannosidase in leukaemic and non leukaemic cells 50
Functional metaproteome analysis of microbial populations in enrichment cultures on polycyclic aromatic hydrocarbons 49
Effect of pH on potassium metabisulphite biocidic activity against yeast and human cell cultures 49
Potassium metabisulfite treatement alters human fibroblast protein expression pattern. 49
Direct brain gene transfer strategy for Tay-Sachs disease 48
Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization 48
Curcumin Analogue C1 Promotes Hex and Gal Recruitment to the Plasma Membrane via mTORC1-Independent TFEB Activation 48
Carbon dioxide capture at gas emission site by carbonic anhidrase 47
New perspectives for the diagnosis of Alzheimer's disease. 46
Effect of potassium metabisulfite in human fibroblast. 46
null 45
Identification of plasma membrane associated mature B-hexosaminidase A, active towards GM2 ganglioside, in human fibroblasts 45
Restoration of the GM2 ganglioside metabolism in bone marrow-derived stromal cells from Tay-Sachs disease animal model 45
Glycosphingolipid metabolism is affected by beta-hexosaminidase over-expression in mammalian cells 45
Transcriptional regulation of glycosphingolipids degrating enzymes 45
Lysosomal Exocytosis, Exosome Release and Secretory Autophagy: The Autophagic- and Endo-Lysosomal Systems Go Extracellular 45
Pig kidney dopa decarboxylase: inactivation by iodoacetamide and sequence of the carboxyamidomethylcysteine-containing peptide. 44
Evidence for altered late endosomal-lysosomal compartment in Sandhoff fibroblasts 44
Cathepsin L increased level upon Ras mutants expression: the role of p38 and p44/42 MAPK signaling pathways 43
PROMOTER CHARACTERIZATION AND STRUCTURE OF THE GENE ENCODING THE MOUSE LYSOSOMAL -D-MANNOSIDASE 43
TFEB overexpression promotes the translocation of lysosomal glycohydrolases beta-hexosaminidase and beta-galactosidase to cell surface lipid microdomains 43
Gene therapy approach for Tay-Sachs Disease 43
Time-resolved extrinsic fluorescence of aromatic-L-amino-acid decarboxylase. 42
β-Hexosaminidase α-subunit overexpression affects lipid microdomain glycohydrolases content 42
In vivo gene transfer strategy for Tay-Sachs disease restores the GM2 ganglioside in the brain of the animal model 42
Biocompatible Polymer Nanoparticles for Drug Delivery Applications in Cancer and Neurodegenerative Disorder Therapies 42
Presenilin genes and Alzheimer's Disease 41
Stereospecificity of sodium borohydride reduction of pig kidney dopa decarboxylase. 41
Derivatized nanoparticle for CSN-target drug delivery 39
Proteome characterization of a microbial community response to polycyclic aromatic hydrocarbons exposure. 39
Impairment of lysosomal system in neurodegenerative diseases 39
Chemical modification of pig kidney 3,4-dihydroxyphenylalanine decarboxylase with diethyl pyrocarbonate. Evidence for an essential histidyl residue. 38
Directed hexa gene transfer therapy for Tay-Sachs disease provides a wide brain distribution of the B-Hexosaminidase a and restores the GM2 ganglioside metabolism 38
Evidence for the regulation of beta-N-acetylhexosaminidase expression during pregnancy in the rat 38
Modified PLGA-NPS able to cross the blood-brain barrier for the delivery of lysosomal enzymes in llysosomal storage disease 38
mTOR Signaling and Neural Stem Cells: The Tuberous Sclerosis Complex Model 38
Ras mutants specifically regulates lysosomal glycohydrolases activity in different cell models. 37
Rapamycin-loaded solid lipid nanoparticles for brain targeting 37
Limited tryptic proteolysis of pig kidney 3,4-dihydroxyphenylalanine decarboxylase. 36
Recruitment of plasma membrane β-galactosidase and β-hexosaminidase in lipid rafts upon T-cell activation 36
Phospholipid fatty acid remodeling and carbonylated protein increase in extracellular vesicles released by airway epithelial cells exposed to cigarette smoke extract 35
Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. 35
Gene Therapy of Tay-Sachs disease 35
Extracellular Vesicles as New Players in Cellular Senescence 35
Purification and characterization of rat-liver 3,4-dihydroxyphenylalanine decarboxylase. 33
Regulation of lysosomal genes by miRNA 33
TOWARDS A GENE THERAPY APPROACH FOR TAY-SACHS DISEASE 33
Plasma membrane associated beta-hexosaminidase: biological significance and regulation 32
Presenilin genes and Alzheimer's Disease 32
null 32
Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. 31
Evidence for altered late endosomal-lysosomal compartment in GM2 gangliosidosis fibroblasts 31
Muscle as a putative producer of acid alpha-glucosidase for glycogenosys type ii gene therapy 31
Solid lipid nanoparticle as a tool to deliver mTOR inhibitors 31
Occurrence of an anomalous endocytic compartment in fibroblasts from Sandhoff disease patients 31
Totale 5.028
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Categoria #
all - tutte 20.872
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.872
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020499 12 7 79 10 86 5 89 11 84 47 18 51
2020/20211.019 4 82 36 80 293 53 78 8 136 32 96 121
2021/2022849 14 159 25 44 22 9 10 287 18 15 94 152
2022/20231.649 121 221 19 137 159 211 6 69 623 5 62 16
2023/2024693 60 64 45 23 5 7 152 9 100 21 106 101
2024/202525 25 0 0 0 0 0 0 0 0 0 0 0
Totale 5.351