IRIS - Res&Arch Institutional Research Information System - Research & Archive

TANCINI, Brunella
 Distribuzione geografica
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Continente #
NA - Nord America 2.697
EU - Europa 2.110
AS - Asia 889
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 2
SA - Sud America 2
AF - Africa 1
Totale 5.705
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Nazione #
US - Stati Uniti d'America 2.692
UA - Ucraina 535
IE - Irlanda 492
SG - Singapore 358
IT - Italia 290
SE - Svezia 253
HK - Hong Kong 227
FI - Finlandia 131
DE - Germania 122
CN - Cina 119
VN - Vietnam 107
RU - Federazione Russa 100
GB - Regno Unito 61
TR - Turchia 34
FR - Francia 32
NL - Olanda 21
BE - Belgio 20
KR - Corea 15
CH - Svizzera 13
UZ - Uzbekistan 11
AT - Austria 10
PL - Polonia 9
MY - Malesia 7
RO - Romania 6
CZ - Repubblica Ceca 4
IR - Iran 4
CA - Canada 3
ES - Italia 3
IN - India 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AU - Australia 2
CO - Colombia 2
DK - Danimarca 2
EU - Europa 2
HU - Ungheria 2
LB - Libano 2
MX - Messico 2
HR - Croazia 1
IL - Israele 1
LV - Lettonia 1
MA - Marocco 1
MD - Moldavia 1
SK - Slovacchia (Repubblica Slovacca) 1
TW - Taiwan 1
Totale 5.705
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Città #
Chandler 565
Dublin 492
Singapore 300
Jacksonville 296
San Mateo 238
Hong Kong 226
Boardman 172
Ann Arbor 114
Perugia 114
Santa Clara 114
Medford 110
Princeton 110
Dong Ket 106
Wilmington 91
Ashburn 66
Andover 63
Des Moines 58
Beijing 45
Altamura 43
Saint Petersburg 35
Lawrence 33
Izmir 32
Helsinki 27
Shanghai 23
Woodbridge 23
Philadelphia 21
Brussels 19
Norwalk 19
Munich 15
Seoul 15
Auburn Hills 14
Los Angeles 13
Redmond 12
Falls Church 11
Milan 11
San Paolo di Civitate 10
Rome 9
Dronten 8
San Diego 8
Seattle 8
Kuala Lumpur 7
Amsterdam 6
Dallas 6
Florence 6
New York 6
Den Haag 5
Bologna 4
Chicago 4
Houston 4
Isfahan 4
Redwood City 4
Calarasi 3
Cattolica 3
Desio 3
Frankfurt Am Main 3
Little Rock 3
Padova 3
Rende 3
Scandicci 3
Sesto Fiorentino 3
Taranto 3
Vienna 3
Aci Sant'Antonio 2
Atlanta 2
Bogotá 2
Brno 2
Castello di Godego 2
Cormeilles-en-Parisis 2
Giaveno 2
Kunming 2
Lappeenranta 2
Lausanne 2
Livorno Ferraris 2
Macerata 2
Mexico City 2
Morwell 2
Moscow 2
Nanjing 2
Pune 2
Reggio Emilia 2
Santiago De Compostela 2
Shenyang 2
Silea 2
Szigetszentmiklos 2
Tappahannock 2
Timisoara 2
Toronto 2
Valenzano 2
Birmingham 1
Bratislava 1
Casalecchio di Reno 1
Chengdu 1
Chisinau 1
Clearwater 1
Copenhagen 1
Edinburgh 1
Esslingen am Neckar 1
Fairfield 1
Falkenstein 1
Groningen 1
Totale 3.842
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Nome #
FORMULAZIONE E CARATTERIZZAZIONE DI NUOVI TIPI DI NANOPARTICELLE PER STRATEGIE DI “DRUG DELIVERY” A LIVELLO CEREBRALE 102
In vivo HSV-1 T0Ahex gene transfer strategy for Tay-Sachs disease provides a wide distribution of B-Hexosaminidase A and restores the GM2 ganglioside metabolims in the brain animal model 95
Identification and characterization of mature beta-hexosaminidases associated with human placenta lysosomal membrane 95
Adenoviral and AAV vectors for an efficient intracerebral gene transfer in the Sandhoff mouse model 94
Use of Polylactide-Co-Glycolide-Nanoparticles for Lysosomal Delivery of a Therapeutic Enzyme in Glycogenesis Type II Fibroblasts 81
Restoration of hexosaminidase A activity and GM2 ganglioside metabolism in cells from patients with Tay-Sachs Disease 80
Expression of human a-subunit gene in the central nervous system of the Tay-Sachs animal model 80
beta-hexosaminidase over-expression affects glycosphingolipid metabolism in mammalian cells-52° Congresso SIB 79
Bicistronic lentiviral vector corrects beta-hexosaminidase deficiency in transduced and cross-corrected human Sandhoff fibroblasts. 77
Absence of metabolic cross-correction in tay-sachs cells: implication in gene therapy 76
Recruitment of beta-hexosaminidase activity on plasma membrane and human T-cell activation-52° Congresso SIB 74
Methods to Discriminate the Distribution of Acidic Glycohydrolases Between the Endosomal–Lysosomal Systems and the Plasma MembraneEndosome Signaling Part A 72
Oncogenic H-Ras Up-Regulates Acid β-Hexosaminidase by a Mechanism Dependent on the Autophagy Regulator TFEB 71
A direct gene transfer strategy via brain internal capsule reverses the biochemical defect in Tay-Sachs disease 71
Sistemi di "Drug delivery di B-esosaminidasi nella mallattia di Tay-Sachs 69
Alpha and Beta subunits of b-N-acethyl-hexosaminidase are differently regulated during the mammalian brain development: implication for Tay-Sachs disease therapy 69
Assessment of safety and efficiency of nitrogen organic fertilizers from animal-based Protein Hydrolysates - a laboratory multidisciplinary approach 69
Evaluation of a LC-MS method for everolimus preclinical determination in brain by using [13C2D4]RAD001 internal standard 69
Bicistronic lentiviral vector corrects beta-hexosaminidase deficiency in transduced and cross-corrected human Sandhoff fibroblasts. 68
Plasma membrane associated beta-hexosaminidase activity increases during human T-cells activation 67
Jurkat T-cell stimulation up-regulates the expression of lysosomal β-hexosaminidase and β-galactosidase and triggers their recruitment to lipid microdomains 67
Glycohydrolases β-hexosaminidase and β-galactosidase are associated with lipid microdomains of Jurkat T-lymphocytes 67
Acidic glycohydrolases localization and regulation: pathological implication 67
Effect of Curcumin on Protein Damage Induced by Rotenone in Dopaminergic PC12 Cells 67
Presenilin genes and Alzheimer's disease 65
Processing and transport of B-hexosaminidase in the DAUDI leukaemic cell line 65
Absence of metabolic cross-correction in Tay-Sachs cells: implication in gene therapy 65
NANOPARTICLE-DRIVEN DRUG DELIVERY TO THE CNS: COMPARISON OF PLGA AND LIPID-BASED NAOPARTICLES IN MOUSE MODEL OF NEURODEGENERATIVE DISEASES 65
In vivo gene therapy approach using herpes simplex vector for Tay-Sachs disease 64
An essential arginine residue at the binding site of pig kidney 3,4-dihydroxyphenylalanine decarboxylase. 62
Presenilin genes and Alzheimer's disease 61
Human plasma membrane associated B-hexosaminidase A Hydrolizes GM2 ganglioside 61
Metagenomic and Metaproteomic Characterization of Enrichment Cultures on Polycyclic Aromatic Hydrocarbons 61
Extending lifespan through autophagy stimulation: a future perspective 61
Plasma membrane β-galactosidase and β-hexosaminidase are associated to lipid raft of Jurkat T-cell upon raft clustering. 60
Abnormal cortical lysosomal β-hexosaminidase and β-galactosidase activity at post-synaptic sites during Alzheimer's disease progression 60
Brain-directed gene transfer therapy for Tay-Sachs disease gives rice a wider distribution of the B-Hexosaminidase A 59
Cells over-expressing Ras show modulation of lysosomal enzymes activity 59
Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. 59
β-Hexosaminidase over-expression affects lysosomal glycohydrolases expression and glycosphingolipid metabolism in mammalian cells 58
Identification and characterization of a fully processed beta-hexosaminidase isoform associated to lysosomal membrane-52° Congresso SIB 57
Characterization of human lysosomal α-D-mannosidase in leukaemic and non leukaemic cells 57
The Role of Extracellular Vesicles in Viral Infection and Transmission 57
Human lysosomal α-D-mannosidase regulation in promyelocytic leukaemia cells. 56
Potassium metabisulfite treatement alters human fibroblast protein expression pattern. 56
Effect of potassium metabisulfite in human fibroblast. 56
TFEB activation promotes the recruitment of lysosomal glycohydrolases β-hexosaminidase and β-galactosidase to the plasma membrane 56
Carbon dioxide capture at gas emission site by carbonic anhidrase 55
FIBROBLASTS FROM PS1 MUTATED PRE-SYMPTOMATIC SUBJECTS AND ALZHEIMER’S DISEASE PATIENTS SHARE A UNIQUE PROTEIN LEVELS PROFILE. 54
Functional metaproteome analysis of microbial populations in enrichment cultures on polycyclic aromatic hydrocarbons 54
Effect of pH on potassium metabisulphite biocidic activity against yeast and human cell cultures 54
Curcumin Analogue C1 Promotes Hex and Gal Recruitment to the Plasma Membrane via mTORC1-Independent TFEB Activation 54
Transcriptional regulation of glycosphingolipids degrating enzymes 53
Direct brain gene transfer strategy for Tay-Sachs disease 52
New perspectives for the diagnosis of Alzheimer's disease. 51
TFEB overexpression promotes the translocation of lysosomal glycohydrolases beta-hexosaminidase and beta-galactosidase to cell surface lipid microdomains 51
Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization 51
Glycosphingolipid metabolism is affected by beta-hexosaminidase over-expression in mammalian cells 50
PROMOTER CHARACTERIZATION AND STRUCTURE OF THE GENE ENCODING THE MOUSE LYSOSOMAL -D-MANNOSIDASE 50
Lysosomal Exocytosis, Exosome Release and Secretory Autophagy: The Autophagic- and Endo-Lysosomal Systems Go Extracellular 50
Identification of plasma membrane associated mature B-hexosaminidase A, active towards GM2 ganglioside, in human fibroblasts 49
Cathepsin L increased level upon Ras mutants expression: the role of p38 and p44/42 MAPK signaling pathways 49
Restoration of the GM2 ganglioside metabolism in bone marrow-derived stromal cells from Tay-Sachs disease animal model 49
Pig kidney dopa decarboxylase: inactivation by iodoacetamide and sequence of the carboxyamidomethylcysteine-containing peptide. 48
Evidence for altered late endosomal-lysosomal compartment in Sandhoff fibroblasts 48
Derivatized nanoparticle for CSN-target drug delivery 48
Biocompatible Polymer Nanoparticles for Drug Delivery Applications in Cancer and Neurodegenerative Disorder Therapies 48
Gene therapy approach for Tay-Sachs Disease 47
In vivo gene transfer strategy for Tay-Sachs disease restores the GM2 ganglioside in the brain of the animal model 47
Time-resolved extrinsic fluorescence of aromatic-L-amino-acid decarboxylase. 46
β-Hexosaminidase α-subunit overexpression affects lipid microdomain glycohydrolases content 46
Presenilin genes and Alzheimer's Disease 45
Stereospecificity of sodium borohydride reduction of pig kidney dopa decarboxylase. 45
null 45
Chemical modification of pig kidney 3,4-dihydroxyphenylalanine decarboxylase with diethyl pyrocarbonate. Evidence for an essential histidyl residue. 44
Proteome characterization of a microbial community response to polycyclic aromatic hydrocarbons exposure. 44
Impairment of lysosomal system in neurodegenerative diseases 44
Evidence for the regulation of beta-N-acetylhexosaminidase expression during pregnancy in the rat 43
Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. 43
Phospholipid fatty acid remodeling and carbonylated protein increase in extracellular vesicles released by airway epithelial cells exposed to cigarette smoke extract 42
Directed hexa gene transfer therapy for Tay-Sachs disease provides a wide brain distribution of the B-Hexosaminidase a and restores the GM2 ganglioside metabolism 42
Modified PLGA-NPS able to cross the blood-brain barrier for the delivery of lysosomal enzymes in llysosomal storage disease 42
Rapamycin-loaded solid lipid nanoparticles for brain targeting 42
mTOR Signaling and Neural Stem Cells: The Tuberous Sclerosis Complex Model 42
Ras mutants specifically regulates lysosomal glycohydrolases activity in different cell models. 41
Limited tryptic proteolysis of pig kidney 3,4-dihydroxyphenylalanine decarboxylase. 40
Recruitment of plasma membrane β-galactosidase and β-hexosaminidase in lipid rafts upon T-cell activation 40
Solid lipid nanoparticle as a tool to deliver mTOR inhibitors 40
Gene Therapy of Tay-Sachs disease 39
Extracellular Vesicles as New Players in Cellular Senescence 39
Presenilin genes and Alzheimer's Disease 38
Occurrence of an anomalous endocytic compartment in fibroblasts from Sandhoff disease patients 38
Purification and characterization of rat-liver 3,4-dihydroxyphenylalanine decarboxylase. 37
Regulation of lysosomal genes by miRNA 37
TOWARDS A GENE THERAPY APPROACH FOR TAY-SACHS DISEASE 37
Plasma membrane associated beta-hexosaminidase: biological significance and regulation 36
Insight into the Role of Extracellular Vesicles in Lysosomal Storage Disorders. 36
Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. 35
Extracellular vesicles under oxidative stress conditions: Biological properties and physiological roles 35
Evidence for altered late endosomal-lysosomal compartment in GM2 gangliosidosis fibroblasts 34
Totale 5.575
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Categoria #
all - tutte 25.695
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 25.695
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020305 0 0 0 0 0 5 89 11 84 47 18 51
2020/20211.021 4 82 36 80 295 53 78 8 136 32 96 121
2021/2022855 14 160 25 44 22 9 10 289 19 16 94 153
2022/20231.655 122 221 19 137 159 211 6 69 628 5 62 16
2023/2024696 60 64 46 23 5 7 152 9 100 21 108 101
2024/2025638 27 166 40 114 212 79 0 0 0 0 0 0
Totale 5.984