IRIS - Res&Arch Institutional Research Information System - Research & Archive

TANCINI, Brunella
 Distribuzione geografica
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Continente #
NA - Nord America 2.734
EU - Europa 2.365
AS - Asia 1.008
SA - Sud America 111
AF - Africa 5
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 3
Totale 6.230
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Nazione #
US - Stati Uniti d'America 2.727
UA - Ucraina 535
IE - Irlanda 492
SG - Singapore 443
IT - Italia 317
RU - Federazione Russa 262
SE - Svezia 253
HK - Hong Kong 244
DE - Germania 149
FI - Finlandia 137
CN - Cina 120
VN - Vietnam 107
BR - Brasile 99
GB - Regno Unito 62
TR - Turchia 36
FR - Francia 32
BE - Belgio 26
NL - Olanda 25
AT - Austria 23
KR - Corea 15
CH - Svizzera 14
UZ - Uzbekistan 13
PL - Polonia 9
MY - Malesia 7
LT - Lituania 6
RO - Romania 6
CA - Canada 4
CZ - Repubblica Ceca 4
ES - Italia 4
IR - Iran 4
AU - Australia 3
AZ - Azerbaigian 3
CO - Colombia 3
DK - Danimarca 3
EC - Ecuador 3
IN - India 3
MA - Marocco 3
PK - Pakistan 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AR - Argentina 2
BD - Bangladesh 2
EU - Europa 2
HU - Ungheria 2
IL - Israele 2
LB - Libano 2
MX - Messico 2
VE - Venezuela 2
CL - Cile 1
DZ - Algeria 1
GD - Grenada 1
HR - Croazia 1
IQ - Iraq 1
JP - Giappone 1
LV - Lettonia 1
MD - Moldavia 1
PY - Paraguay 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
TW - Taiwan 1
ZA - Sudafrica 1
Totale 6.230
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Città #
Chandler 565
Dublin 492
Singapore 335
Jacksonville 296
Hong Kong 243
San Mateo 238
Boardman 172
Perugia 122
Ann Arbor 114
Santa Clara 114
Medford 110
Princeton 110
Dong Ket 106
Wilmington 91
Moscow 81
Ashburn 66
Andover 63
Des Moines 58
Beijing 46
Altamura 43
Saint Petersburg 35
Helsinki 33
Lawrence 33
Izmir 32
Brussels 25
Shanghai 23
Woodbridge 23
Philadelphia 21
Norwalk 19
Los Angeles 16
Munich 15
Seoul 15
Auburn Hills 14
Falkenstein 13
Milan 13
Redmond 12
Rome 12
Falls Church 11
Nuremberg 11
San Paolo di Civitate 10
Amsterdam 9
Dronten 8
Florence 8
San Diego 8
Seattle 8
Bologna 7
Kuala Lumpur 7
Vienna 7
Dallas 6
New York 6
Den Haag 5
Rio de Janeiro 5
Chicago 4
Houston 4
Isfahan 4
Recife 4
Redwood City 4
São Gonçalo 4
Baku 3
Belo Horizonte 3
Bogotá 3
Brasília 3
Calarasi 3
Cattolica 3
Desio 3
Frankfurt Am Main 3
Frankfurt am Main 3
Little Rock 3
Padova 3
Rende 3
Scandicci 3
Sesto Fiorentino 3
Taranto 3
The Dalles 3
Toledo 3
Toronto 3
Aci Sant'Antonio 2
Aracaju 2
Atlanta 2
Brno 2
Castello di Godego 2
Catanduva 2
Cormeilles-en-Parisis 2
Council Bluffs 2
Curitiba 2
Duque de Caxias 2
Giaveno 2
Jerusalem 2
Juiz de Fora 2
Kunming 2
Lappeenranta 2
Lausanne 2
Livorno Ferraris 2
Macerata 2
Mexico City 2
Morwell 2
Nanjing 2
Naples 2
Newark 2
Paternò 2
Totale 4.061
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Nome #
FORMULAZIONE E CARATTERIZZAZIONE DI NUOVI TIPI DI NANOPARTICELLE PER STRATEGIE DI “DRUG DELIVERY” A LIVELLO CEREBRALE 109
In vivo HSV-1 T0Ahex gene transfer strategy for Tay-Sachs disease provides a wide distribution of B-Hexosaminidase A and restores the GM2 ganglioside metabolims in the brain animal model 101
Adenoviral and AAV vectors for an efficient intracerebral gene transfer in the Sandhoff mouse model 100
Identification and characterization of mature beta-hexosaminidases associated with human placenta lysosomal membrane 100
Use of Polylactide-Co-Glycolide-Nanoparticles for Lysosomal Delivery of a Therapeutic Enzyme in Glycogenesis Type II Fibroblasts 87
beta-hexosaminidase over-expression affects glycosphingolipid metabolism in mammalian cells-52° Congresso SIB 86
Bicistronic lentiviral vector corrects beta-hexosaminidase deficiency in transduced and cross-corrected human Sandhoff fibroblasts. 84
Restoration of hexosaminidase A activity and GM2 ganglioside metabolism in cells from patients with Tay-Sachs Disease 83
Expression of human a-subunit gene in the central nervous system of the Tay-Sachs animal model 82
Absence of metabolic cross-correction in tay-sachs cells: implication in gene therapy 81
Recruitment of beta-hexosaminidase activity on plasma membrane and human T-cell activation-52° Congresso SIB 80
A direct gene transfer strategy via brain internal capsule reverses the biochemical defect in Tay-Sachs disease 78
Bicistronic lentiviral vector corrects beta-hexosaminidase deficiency in transduced and cross-corrected human Sandhoff fibroblasts. 77
Methods to Discriminate the Distribution of Acidic Glycohydrolases Between the Endosomal–Lysosomal Systems and the Plasma MembraneEndosome Signaling Part A 75
Effect of Curcumin on Protein Damage Induced by Rotenone in Dopaminergic PC12 Cells 75
Alpha and Beta subunits of b-N-acethyl-hexosaminidase are differently regulated during the mammalian brain development: implication for Tay-Sachs disease therapy 74
Acidic glycohydrolases localization and regulation: pathological implication 74
Assessment of safety and efficiency of nitrogen organic fertilizers from animal-based Protein Hydrolysates - a laboratory multidisciplinary approach 73
Oncogenic H-Ras Up-Regulates Acid β-Hexosaminidase by a Mechanism Dependent on the Autophagy Regulator TFEB 73
Evaluation of a LC-MS method for everolimus preclinical determination in brain by using [13C2D4]RAD001 internal standard 73
Sistemi di "Drug delivery di B-esosaminidasi nella mallattia di Tay-Sachs 71
Plasma membrane associated beta-hexosaminidase activity increases during human T-cells activation 71
Glycohydrolases β-hexosaminidase and β-galactosidase are associated with lipid microdomains of Jurkat T-lymphocytes 71
Presenilin genes and Alzheimer's disease 69
Absence of metabolic cross-correction in Tay-Sachs cells: implication in gene therapy 69
Jurkat T-cell stimulation up-regulates the expression of lysosomal β-hexosaminidase and β-galactosidase and triggers their recruitment to lipid microdomains 69
Human plasma membrane associated B-hexosaminidase A Hydrolizes GM2 ganglioside 68
NANOPARTICLE-DRIVEN DRUG DELIVERY TO THE CNS: COMPARISON OF PLGA AND LIPID-BASED NAOPARTICLES IN MOUSE MODEL OF NEURODEGENERATIVE DISEASES 68
Curcumin Analogue C1 Promotes Hex and Gal Recruitment to the Plasma Membrane via mTORC1-Independent TFEB Activation 67
Processing and transport of B-hexosaminidase in the DAUDI leukaemic cell line 66
In vivo gene therapy approach using herpes simplex vector for Tay-Sachs disease 66
An essential arginine residue at the binding site of pig kidney 3,4-dihydroxyphenylalanine decarboxylase. 66
Abnormal cortical lysosomal β-hexosaminidase and β-galactosidase activity at post-synaptic sites during Alzheimer's disease progression 65
Presenilin genes and Alzheimer's disease 64
Extending lifespan through autophagy stimulation: a future perspective 64
The Role of Extracellular Vesicles in Viral Infection and Transmission 64
Cells over-expressing Ras show modulation of lysosomal enzymes activity 63
Brain-directed gene transfer therapy for Tay-Sachs disease gives rice a wider distribution of the B-Hexosaminidase A 62
Identification and characterization of a fully processed beta-hexosaminidase isoform associated to lysosomal membrane-52° Congresso SIB 62
Metagenomic and Metaproteomic Characterization of Enrichment Cultures on Polycyclic Aromatic Hydrocarbons 62
Characterization of human lysosomal α-D-mannosidase in leukaemic and non leukaemic cells 62
Plasma membrane β-galactosidase and β-hexosaminidase are associated to lipid raft of Jurkat T-cell upon raft clustering. 61
Effect of potassium metabisulfite in human fibroblast. 61
β-Hexosaminidase over-expression affects lysosomal glycohydrolases expression and glycosphingolipid metabolism in mammalian cells 61
Potassium metabisulfite treatement alters human fibroblast protein expression pattern. 60
Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. 60
Phospholipid fatty acid remodeling and carbonylated protein increase in extracellular vesicles released by airway epithelial cells exposed to cigarette smoke extract 59
Carbon dioxide capture at gas emission site by carbonic anhidrase 59
TFEB activation promotes the recruitment of lysosomal glycohydrolases β-hexosaminidase and β-galactosidase to the plasma membrane 59
Effect of pH on potassium metabisulphite biocidic activity against yeast and human cell cultures 58
Human lysosomal α-D-mannosidase regulation in promyelocytic leukaemia cells. 57
Lysosomal Exocytosis, Exosome Release and Secretory Autophagy: The Autophagic- and Endo-Lysosomal Systems Go Extracellular 57
Direct brain gene transfer strategy for Tay-Sachs disease 56
FIBROBLASTS FROM PS1 MUTATED PRE-SYMPTOMATIC SUBJECTS AND ALZHEIMER’S DISEASE PATIENTS SHARE A UNIQUE PROTEIN LEVELS PROFILE. 56
Transcriptional regulation of glycosphingolipids degrating enzymes 56
Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization 56
New perspectives for the diagnosis of Alzheimer's disease. 55
Biocompatible Polymer Nanoparticles for Drug Delivery Applications in Cancer and Neurodegenerative Disorder Therapies 55
Cathepsin L increased level upon Ras mutants expression: the role of p38 and p44/42 MAPK signaling pathways 54
Restoration of the GM2 ganglioside metabolism in bone marrow-derived stromal cells from Tay-Sachs disease animal model 54
Functional metaproteome analysis of microbial populations in enrichment cultures on polycyclic aromatic hydrocarbons 54
Identification of plasma membrane associated mature B-hexosaminidase A, active towards GM2 ganglioside, in human fibroblasts 53
PROMOTER CHARACTERIZATION AND STRUCTURE OF THE GENE ENCODING THE MOUSE LYSOSOMAL -D-MANNOSIDASE 53
TFEB overexpression promotes the translocation of lysosomal glycohydrolases beta-hexosaminidase and beta-galactosidase to cell surface lipid microdomains 53
In vivo gene transfer strategy for Tay-Sachs disease restores the GM2 ganglioside in the brain of the animal model 53
Stereospecificity of sodium borohydride reduction of pig kidney dopa decarboxylase. 52
Pig kidney dopa decarboxylase: inactivation by iodoacetamide and sequence of the carboxyamidomethylcysteine-containing peptide. 52
Evidence for altered late endosomal-lysosomal compartment in Sandhoff fibroblasts 52
Glycosphingolipid metabolism is affected by beta-hexosaminidase over-expression in mammalian cells 52
Derivatized nanoparticle for CSN-target drug delivery 52
Presenilin genes and Alzheimer's Disease 51
β-Hexosaminidase α-subunit overexpression affects lipid microdomain glycohydrolases content 51
Gene therapy approach for Tay-Sachs Disease 51
Chemical modification of pig kidney 3,4-dihydroxyphenylalanine decarboxylase with diethyl pyrocarbonate. Evidence for an essential histidyl residue. 50
Time-resolved extrinsic fluorescence of aromatic-L-amino-acid decarboxylase. 50
Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. 50
Impairment of lysosomal system in neurodegenerative diseases 49
Modified PLGA-NPS able to cross the blood-brain barrier for the delivery of lysosomal enzymes in llysosomal storage disease 48
Evidence for the regulation of beta-N-acetylhexosaminidase expression during pregnancy in the rat 47
Proteome characterization of a microbial community response to polycyclic aromatic hydrocarbons exposure. 46
mTOR Signaling and Neural Stem Cells: The Tuberous Sclerosis Complex Model 46
Extracellular vesicles under oxidative stress conditions: Biological properties and physiological roles 46
null 45
TOWARDS A GENE THERAPY APPROACH FOR TAY-SACHS DISEASE 44
Extracellular Vesicles as New Players in Cellular Senescence 44
Limited tryptic proteolysis of pig kidney 3,4-dihydroxyphenylalanine decarboxylase. 43
Impairment of lysosomal system in neurodegenerative diseases 43
Directed hexa gene transfer therapy for Tay-Sachs disease provides a wide brain distribution of the B-Hexosaminidase a and restores the GM2 ganglioside metabolism 43
Solid lipid nanoparticle as a tool to deliver mTOR inhibitors 43
Evidence for the presence of human B-hexosaminidase B as lysosomal membrane associated protein 42
Ras mutants specifically regulates lysosomal glycohydrolases activity in different cell models. 42
Recruitment of plasma membrane β-galactosidase and β-hexosaminidase in lipid rafts upon T-cell activation 42
Rapamycin-loaded solid lipid nanoparticles for brain targeting 42
Gene Therapy of Tay-Sachs disease 42
Insight into the Role of Extracellular Vesicles in Lysosomal Storage Disorders. 42
Purification and characterization of rat-liver 3,4-dihydroxyphenylalanine decarboxylase. 41
Plasma membrane associated beta-hexosaminidase: biological significance and regulation 41
Presenilin genes and Alzheimer's Disease 41
Occurrence of an anomalous endocytic compartment in fibroblasts from Sandhoff disease patients 41
Regulation of lysosomal genes by miRNA 40
Totale 6.020
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Categoria #
all - tutte 29.435
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 29.435
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020116 0 0 0 0 0 0 0 0 0 47 18 51
2020/20211.021 4 82 36 80 295 53 78 8 136 32 96 121
2021/2022855 14 160 25 44 22 9 10 289 19 16 94 153
2022/20231.655 122 221 19 137 159 211 6 69 628 5 62 16
2023/2024696 60 64 46 23 5 7 152 9 100 21 108 101
2024/20251.172 27 166 40 114 212 85 68 104 285 71 0 0
Totale 6.518