IRIS - Res&Arch Institutional Research Information System - Research & Archive

TANCINI, Brunella
 Distribuzione geografica
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Continente #
NA - Nord America 3.360
EU - Europa 2.622
AS - Asia 2.188
SA - Sud America 403
AF - Africa 39
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 3
Totale 8.619
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Nazione #
US - Stati Uniti d'America 3.296
SG - Singapore 946
UA - Ucraina 541
IE - Irlanda 493
HK - Hong Kong 379
IT - Italia 341
CN - Cina 333
BR - Brasile 332
RU - Federazione Russa 265
SE - Svezia 265
VN - Vietnam 237
DE - Germania 209
FI - Finlandia 152
GB - Regno Unito 112
KR - Corea 108
TR - Turchia 57
FR - Francia 53
NL - Olanda 35
PL - Polonia 35
CA - Canada 33
AR - Argentina 30
BE - Belgio 26
MX - Messico 25
AT - Austria 24
ZA - Sudafrica 22
IN - India 20
BD - Bangladesh 19
ES - Italia 18
CH - Svizzera 16
JP - Giappone 16
UZ - Uzbekistan 14
LT - Lituania 11
EC - Ecuador 10
CO - Colombia 9
MY - Malesia 7
RO - Romania 7
CZ - Repubblica Ceca 6
ID - Indonesia 6
IQ - Iraq 6
LB - Libano 6
PY - Paraguay 6
VE - Venezuela 6
AE - Emirati Arabi Uniti 5
AZ - Azerbaigian 5
MA - Marocco 5
UY - Uruguay 5
IR - Iran 4
PK - Pakistan 4
AU - Australia 3
DK - Danimarca 3
IL - Israele 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BA - Bosnia-Erzegovina 2
CL - Cile 2
DZ - Algeria 2
EG - Egitto 2
EU - Europa 2
HU - Ungheria 2
JO - Giordania 2
MD - Moldavia 2
ML - Mali 2
NP - Nepal 2
PE - Perù 2
PH - Filippine 2
TN - Tunisia 2
BH - Bahrain 1
BO - Bolivia 1
BS - Bahamas 1
CI - Costa d'Avorio 1
CY - Cipro 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
GD - Grenada 1
GT - Guatemala 1
HN - Honduras 1
HR - Croazia 1
KE - Kenya 1
KZ - Kazakistan 1
LV - Lettonia 1
NG - Nigeria 1
OM - Oman 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
TT - Trinidad e Tobago 1
TW - Taiwan 1
YE - Yemen 1
Totale 8.619
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Città #
Singapore 628
Chandler 565
Dublin 493
Hong Kong 377
Jacksonville 296
San Mateo 238
Ashburn 187
Boardman 172
Santa Clara 126
Perugia 122
Ann Arbor 114
Medford 110
Princeton 110
Seoul 107
Dong Ket 106
Wilmington 91
Beijing 84
Moscow 81
Andover 63
Munich 63
Des Moines 59
Los Angeles 57
New York 47
Ho Chi Minh City 44
Altamura 43
Piscataway 39
Saint Petersburg 35
São Paulo 34
Helsinki 33
Lawrence 33
Izmir 32
Hanoi 28
Shanghai 26
Brussels 25
Warsaw 23
Woodbridge 23
Philadelphia 21
Council Bluffs 19
Johannesburg 19
Norwalk 19
Amsterdam 17
Montreal 16
Tokyo 16
Atlanta 15
The Dalles 15
Auburn Hills 14
Denver 14
Frankfurt am Main 14
Poplar 14
Rome 14
Turku 14
Chicago 13
Dallas 13
Falkenstein 13
Milan 13
San Francisco 13
Belo Horizonte 12
Brooklyn 12
Nuremberg 12
Porto Alegre 12
Redmond 12
Rio de Janeiro 12
Seattle 12
Ankara 11
Boston 11
Falls Church 11
London 11
Florence 10
San Paolo di Civitate 10
Mexico City 9
Stockholm 9
Toronto 9
Dronten 8
Houston 8
San Diego 8
Çankaya 8
Bologna 7
Chennai 7
Columbus 7
Guarulhos 7
Haiphong 7
Kuala Lumpur 7
Manchester 7
Vienna 7
Brasília 6
Curitiba 6
Guangzhou 6
Shijiazhuang 6
Aracaju 5
Baku 5
Biên Hòa 5
Campinas 5
Den Haag 5
Dhaka 5
Ninh Bình 5
Orem 5
Phoenix 5
Recife 5
Salvador 5
Zhengzhou 5
Totale 5.367
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Nome #
FORMULAZIONE E CARATTERIZZAZIONE DI NUOVI TIPI DI NANOPARTICELLE PER STRATEGIE DI “DRUG DELIVERY” A LIVELLO CEREBRALE 140
Identification and characterization of mature beta-hexosaminidases associated with human placenta lysosomal membrane 126
Adenoviral and AAV vectors for an efficient intracerebral gene transfer in the Sandhoff mouse model 119
Bicistronic lentiviral vector corrects beta-hexosaminidase deficiency in transduced and cross-corrected human Sandhoff fibroblasts. 116
Absence of metabolic cross-correction in tay-sachs cells: implication in gene therapy 116
In vivo HSV-1 T0Ahex gene transfer strategy for Tay-Sachs disease provides a wide distribution of B-Hexosaminidase A and restores the GM2 ganglioside metabolims in the brain animal model 113
beta-hexosaminidase over-expression affects glycosphingolipid metabolism in mammalian cells-52° Congresso SIB 110
Methods to Discriminate the Distribution of Acidic Glycohydrolases Between the Endosomal–Lysosomal Systems and the Plasma MembraneEndosome Signaling Part A 109
Effect of Curcumin on Protein Damage Induced by Rotenone in Dopaminergic PC12 Cells 108
A direct gene transfer strategy via brain internal capsule reverses the biochemical defect in Tay-Sachs disease 104
Recruitment of beta-hexosaminidase activity on plasma membrane and human T-cell activation-52° Congresso SIB 103
Absence of metabolic cross-correction in Tay-Sachs cells: implication in gene therapy 103
Assessment of safety and efficiency of nitrogen organic fertilizers from animal-based Protein Hydrolysates - a laboratory multidisciplinary approach 100
Abnormal cortical lysosomal β-hexosaminidase and β-galactosidase activity at post-synaptic sites during Alzheimer's disease progression 100
Extending lifespan through autophagy stimulation: a future perspective 99
Restoration of hexosaminidase A activity and GM2 ganglioside metabolism in cells from patients with Tay-Sachs Disease 97
Expression of human a-subunit gene in the central nervous system of the Tay-Sachs animal model 97
Bicistronic lentiviral vector corrects beta-hexosaminidase deficiency in transduced and cross-corrected human Sandhoff fibroblasts. 97
Use of Polylactide-Co-Glycolide-Nanoparticles for Lysosomal Delivery of a Therapeutic Enzyme in Glycogenesis Type II Fibroblasts 97
Plasma membrane associated beta-hexosaminidase activity increases during human T-cells activation 95
An essential arginine residue at the binding site of pig kidney 3,4-dihydroxyphenylalanine decarboxylase. 95
Jurkat T-cell stimulation up-regulates the expression of lysosomal β-hexosaminidase and β-galactosidase and triggers their recruitment to lipid microdomains 95
Acidic glycohydrolases localization and regulation: pathological implication 94
Oncogenic H-Ras Up-Regulates Acid β-Hexosaminidase by a Mechanism Dependent on the Autophagy Regulator TFEB 94
Curcumin Analogue C1 Promotes Hex and Gal Recruitment to the Plasma Membrane via mTORC1-Independent TFEB Activation 94
The Role of Extracellular Vesicles in Viral Infection and Transmission 94
Human plasma membrane associated B-hexosaminidase A Hydrolizes GM2 ganglioside 93
Alpha and Beta subunits of b-N-acethyl-hexosaminidase are differently regulated during the mammalian brain development: implication for Tay-Sachs disease therapy 93
NANOPARTICLE-DRIVEN DRUG DELIVERY TO THE CNS: COMPARISON OF PLGA AND LIPID-BASED NAOPARTICLES IN MOUSE MODEL OF NEURODEGENERATIVE DISEASES 92
Evaluation of a LC-MS method for everolimus preclinical determination in brain by using [13C2D4]RAD001 internal standard 92
Sistemi di "Drug delivery di B-esosaminidasi nella mallattia di Tay-Sachs 91
Glycohydrolases β-hexosaminidase and β-galactosidase are associated with lipid microdomains of Jurkat T-lymphocytes 91
Identification of plasma membrane associated mature B-hexosaminidase A, active towards GM2 ganglioside, in human fibroblasts 89
New perspectives for the diagnosis of Alzheimer's disease. 88
FIBROBLASTS FROM PS1 MUTATED PRE-SYMPTOMATIC SUBJECTS AND ALZHEIMER’S DISEASE PATIENTS SHARE A UNIQUE PROTEIN LEVELS PROFILE. 88
Characterization of human lysosomal α-D-mannosidase in leukaemic and non leukaemic cells 88
Cells over-expressing Ras show modulation of lysosomal enzymes activity 87
In vivo gene therapy approach using herpes simplex vector for Tay-Sachs disease 84
Effect of potassium metabisulfite in human fibroblast. 83
Brain-directed gene transfer therapy for Tay-Sachs disease gives rice a wider distribution of the B-Hexosaminidase A 82
Processing and transport of B-hexosaminidase in the DAUDI leukaemic cell line 82
Transcriptional regulation of glycosphingolipids degrating enzymes 82
Human lysosomal α-D-mannosidase regulation in promyelocytic leukaemia cells. 81
Functional metaproteome analysis of microbial populations in enrichment cultures on polycyclic aromatic hydrocarbons 81
Presenilin genes and Alzheimer's disease 80
Identification and characterization of a fully processed beta-hexosaminidase isoform associated to lysosomal membrane-52° Congresso SIB 80
Restoration of the GM2 ganglioside metabolism in bone marrow-derived stromal cells from Tay-Sachs disease animal model 80
Effect of pH on potassium metabisulphite biocidic activity against yeast and human cell cultures 80
Rapamycin-loaded solid lipid nanoparticles for brain targeting 80
Presenilin genes and Alzheimer's disease 79
Metagenomic and Metaproteomic Characterization of Enrichment Cultures on Polycyclic Aromatic Hydrocarbons 79
Cathepsin L increased level upon Ras mutants expression: the role of p38 and p44/42 MAPK signaling pathways 79
Plasma membrane β-galactosidase and β-hexosaminidase are associated to lipid raft of Jurkat T-cell upon raft clustering. 79
Lysosomal Exocytosis, Exosome Release and Secretory Autophagy: The Autophagic- and Endo-Lysosomal Systems Go Extracellular 79
Carbon dioxide capture at gas emission site by carbonic anhidrase 78
Phospholipid fatty acid remodeling and carbonylated protein increase in extracellular vesicles released by airway epithelial cells exposed to cigarette smoke extract 77
Potassium metabisulfite treatement alters human fibroblast protein expression pattern. 77
β-Hexosaminidase over-expression affects lysosomal glycohydrolases expression and glycosphingolipid metabolism in mammalian cells 77
Evidence for altered late endosomal-lysosomal compartment in Sandhoff fibroblasts 75
Direct brain gene transfer strategy for Tay-Sachs disease 74
Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization 74
Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. 73
Plasma membrane associated beta-hexosaminidase: biological significance and regulation 72
TFEB activation promotes the recruitment of lysosomal glycohydrolases β-hexosaminidase and β-galactosidase to the plasma membrane 72
Extracellular vesicles under oxidative stress conditions: Biological properties and physiological roles 72
Biocompatible Polymer Nanoparticles for Drug Delivery Applications in Cancer and Neurodegenerative Disorder Therapies 71
Impairment of lysosomal system in neurodegenerative diseases 70
Evidence for the regulation of beta-N-acetylhexosaminidase expression during pregnancy in the rat 70
PROMOTER CHARACTERIZATION AND STRUCTURE OF THE GENE ENCODING THE MOUSE LYSOSOMAL -D-MANNOSIDASE 70
TFEB overexpression promotes the translocation of lysosomal glycohydrolases beta-hexosaminidase and beta-galactosidase to cell surface lipid microdomains 70
Chemical modification of pig kidney 3,4-dihydroxyphenylalanine decarboxylase with diethyl pyrocarbonate. Evidence for an essential histidyl residue. 69
Evidence for the presence of human B-hexosaminidase B as lysosomal membrane associated protein 69
Directed hexa gene transfer therapy for Tay-Sachs disease provides a wide brain distribution of the B-Hexosaminidase a and restores the GM2 ganglioside metabolism 68
Identification of lysosomal membrane associated, fully processed beta-hexosaminidase enzyme 67
Glycosphingolipid metabolism is affected by beta-hexosaminidase over-expression in mammalian cells 67
Modified PLGA-NPS able to cross the blood-brain barrier for the delivery of lysosomal enzymes in llysosomal storage disease 67
Extracellular Vesicles as New Players in Cellular Senescence 67
Proteome characterization of a microbial community response to polycyclic aromatic hydrocarbons exposure. 66
Insight into the Role of Extracellular Vesicles in Lysosomal Storage Disorders. 66
Ras mutants specifically regulates lysosomal glycohydrolases activity in different cell models. 65
Derivatized nanoparticle for CSN-target drug delivery 65
Stereospecificity of sodium borohydride reduction of pig kidney dopa decarboxylase. 64
mTOR Signaling and Neural Stem Cells: The Tuberous Sclerosis Complex Model 64
In vivo gene transfer strategy for Tay-Sachs disease restores the GM2 ganglioside in the brain of the animal model 64
β-Hexosaminidase α-subunit overexpression affects lipid microdomain glycohydrolases content 63
Presenilin genes and Alzheimer's Disease 62
Pig kidney dopa decarboxylase: inactivation by iodoacetamide and sequence of the carboxyamidomethylcysteine-containing peptide. 62
Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. 62
Solid lipid nanoparticle as a tool to deliver mTOR inhibitors 62
Impairment of lysosomal system in neurodegenerative diseases 61
Gene therapy approach for Tay-Sachs Disease 60
Role of nitric oxide and melanogenesis in the accomplishment of anticryptococcal activity by the BV-2 microglial cell line. 59
Plasma membrane associated beta-hexosaminidase activity during human T-cells activation 58
Occurrence of an anomalous endocytic compartment in fibroblasts from Sandhoff disease patients 58
Everolimus treatment reduces proliferation of TSC1-deficient adult neural stem/progenitor cells and restores their migration capability. 57
Time-resolved extrinsic fluorescence of aromatic-L-amino-acid decarboxylase. 56
Lysosomal exocytosis: The extracellular role of an intracellular organelle 55
Limited tryptic proteolysis of pig kidney 3,4-dihydroxyphenylalanine decarboxylase. 55
Muscle as a putative producer of acid alpha-glucosidase for glycogenosys type ii gene therapy 55
Recruitment of plasma membrane β-galactosidase and β-hexosaminidase in lipid rafts upon T-cell activation 55
Totale 8.117
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Categoria #
all - tutte 39.438
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.438
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021524 0 0 0 0 0 53 78 8 136 32 96 121
2021/2022855 14 160 25 44 22 9 10 289 19 16 94 153
2022/20231.655 122 221 19 137 159 211 6 69 628 5 62 16
2023/2024696 60 64 46 23 5 7 152 9 100 21 108 101
2024/20251.625 27 166 40 114 212 85 68 104 285 75 298 151
2025/20261.936 258 225 193 554 510 196 0 0 0 0 0 0
Totale 8.907