ORABONA, Ciriana
 Distribuzione geografica
Continente #
NA - Nord America 3.948
EU - Europa 3.402
AS - Asia 2.684
SA - Sud America 405
AF - Africa 49
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 3
Totale 10.497
Nazione #
US - Stati Uniti d'America 3.847
SG - Singapore 1.189
IT - Italia 950
IE - Irlanda 488
HK - Hong Kong 418
CN - Cina 414
VN - Vietnam 353
BR - Brasile 346
RO - Romania 288
UA - Ucraina 272
DE - Germania 255
RU - Federazione Russa 243
SE - Svezia 237
FR - Francia 159
FI - Finlandia 144
GB - Regno Unito 99
KR - Corea 77
IN - India 58
CA - Canada 57
BE - Belgio 50
CZ - Repubblica Ceca 46
PL - Polonia 38
AT - Austria 31
MX - Messico 30
NL - Olanda 30
TR - Turchia 30
JP - Giappone 28
AR - Argentina 22
CH - Svizzera 19
BD - Bangladesh 18
GR - Grecia 18
ES - Italia 15
ZA - Sudafrica 13
EC - Ecuador 12
IQ - Iraq 12
CI - Costa d'Avorio 11
IR - Iran 11
PK - Pakistan 10
UZ - Uzbekistan 10
ID - Indonesia 9
MA - Marocco 9
LT - Lituania 8
VE - Venezuela 7
LB - Libano 6
AE - Emirati Arabi Uniti 5
EU - Europa 5
SA - Arabia Saudita 5
UY - Uruguay 5
AZ - Azerbaigian 4
CO - Colombia 4
KZ - Kazakistan 4
PE - Perù 4
AL - Albania 3
EG - Egitto 3
GT - Guatemala 3
IL - Israele 3
JO - Giordania 3
KE - Kenya 3
TN - Tunisia 3
BG - Bulgaria 2
HU - Ungheria 2
NG - Nigeria 2
NZ - Nuova Zelanda 2
PA - Panama 2
PS - Palestinian Territory 2
PY - Paraguay 2
AM - Armenia 1
AU - Australia 1
BH - Bahrain 1
BO - Bolivia 1
BW - Botswana 1
BZ - Belize 1
CL - Cile 1
CR - Costa Rica 1
CU - Cuba 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
EE - Estonia 1
GA - Gabon 1
GD - Grenada 1
HN - Honduras 1
HR - Croazia 1
JM - Giamaica 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LC - Santa Lucia 1
LK - Sri Lanka 1
LV - Lettonia 1
ML - Mali 1
MN - Mongolia 1
MU - Mauritius 1
MY - Malesia 1
NP - Nepal 1
OM - Oman 1
PH - Filippine 1
PR - Porto Rico 1
QA - Qatar 1
SC - Seychelles 1
SI - Slovenia 1
SR - Suriname 1
Totale 10.492
Città #
Singapore 833
Perugia 561
Chandler 534
Dublin 483
Hong Kong 416
Bucharest 268
San Mateo 239
Ashburn 215
Dong Ket 198
Boardman 197
Santa Clara 161
Redmond 146
Jacksonville 144
Beijing 115
Altamura 111
Munich 105
Medford 103
Wilmington 103
Princeton 101
Ann Arbor 95
Los Angeles 86
Lawrence 82
Seoul 74
Moscow 73
New York 67
Andover 65
Ho Chi Minh City 55
Brussels 50
Dearborn 42
Des Moines 42
The Dalles 42
Falls Church 40
Turku 34
Hanoi 30
Piscataway 29
Saint Petersburg 29
São Paulo 28
Chennai 27
Helsinki 27
Pisa 26
Warsaw 26
Brno 25
Denver 25
Woodbridge 25
Chicago 24
Montreal 24
Norwalk 24
Tokyo 23
Dallas 21
Poplar 21
Izmir 20
Redwood City 20
Brooklyn 19
Rome 19
Atlanta 18
Boston 18
Fremont 18
Nuremberg 18
Orem 18
Vienna 18
Houston 17
Olomouc 17
Chiajna 16
San Paolo di Civitate 16
Stockholm 16
Milan 14
Columbus 13
Vicenza 13
Lappeenranta 12
Manchester 12
Abidjan 11
Johannesburg 11
London 11
Phoenix 11
Seattle 11
Mexico City 10
San Francisco 10
Florence 9
Frankfurt am Main 9
Guangzhou 9
Haiphong 9
Hefei 9
San Diego 9
Amsterdam 8
Belo Horizonte 8
Nanjing 8
Ottawa 8
San Jose 8
Toronto 8
Chengdu 7
Den Haag 7
Falkenstein 7
Querétaro 7
Ankara 6
Auburn Hills 6
Biên Hòa 6
Hanover 6
L’Aquila 6
Paris 6
Shanghai 6
Totale 6.893
Nome #
Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3-dioxygenase1 206
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1 190
A GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune Suppression. 180
Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells 175
Distinct roles of immunoreceptor tyrosine-based motifs in immunosuppressive indoleamine 2,3-dioxygenase 1. 166
Amino-acid sensing and degrading pathways in immune regulation 165
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells 163
Aryl hydrocarbon receptor control of a disease tolerance defence pathway. 159
Identification of a 2-propanol analogue modulating the non-enzymatic function of indoleamine 2,3-dioxygenase 1 154
Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells 154
Amino acid metabolism as drug target in autoimmune diseases 153
Advances in indoleamine 2,3-dioxygenase 1 medicinal chemistry 144
IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII 138
IL‐35Ig–expressing dendritic cells induce tolerance via Arginase 1 137
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy 134
Fragment-based approach to identify IDO1 inhibitor building blocks 133
87P - Towards the identification of the mechanism of action of antitumor 1-methyl-D-tryptophan 131
Cutting edge: Autocrine TGF-beta sustains default tolerogenesis by IDO-competent dendritic cells. 128
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation 128
T cell apoptosis by kynurenines. 125
LPS-conditioned dendritic cells confer endotoxin tolerance contingent on tryptophan catabolism 125
Artocarpus tonkinensis extract inhibits LPS-triggered inflammation markers and suppresses RANKL-induced osteoclastogenesis in RAW264.7 125
Is It Time to Use Probiotics to Prevent or Treat Obesity? 123
A novel mutation of indoleamine 2,3-dioxygenase 1 causes a rapid proteasomal degradation and compromises protein function 117
Tracking Hidden Binding Pockets Along the Molecular Recognition Path of l-Trp to Indoleamine 2,3-Dioxygenase 1 116
Bioadhesive Polymeric Films Based on Red Onion Skins Extract for Wound Treatment: An Innovative and Eco-Friendly Formulation 116
Dendritic cells expressing ectopic IL-35Ig induce IDO-related tolerance in vivo. 114
Aryl hydrocarbon Receptor and RelB control long term expression of Indoleamine 2,3-dioxygenase-1 in endotoxin tolerance 114
Forced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes 113
Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1 in juvenile diabetes 111
A novel metabotropic glutamate receptor 4 allosteric modulator effective in multiple sclerosis experimental autoimmune encephalomyelitis (EAE) mouse model 110
Modulation of natriuretic peptide receptors in human adipose tissue: molecular mechanisms behind the “natriuretic handicap” in morbidly obese patients 110
Antigen-specific immunoregulation by IL-35Ig-transfected dendritic cells 107
A back-door insight into the modulation of Src kinase activity by the polyamine spermidine 106
Different partners, opposite outcomes: A New Perspective of the Immunobiology of Indoleamine 2,3-Dioxygenase 105
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86. 104
Anti-osteoclastogenic activity of Crocus sativus petal extract: turning saffron waste into a valuable resource against bone disruption. 104
Integrated Fragment-Based Approaches on the Route to Novel IDO1 Modulators 103
Preclinical discovery and development of fingolimod for the treatment of multiple sclerosis 103
CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice 102
The TGF-β/IDO axis in infectious tolerance. 102
Novel mutations in the WFS1 gene are associated with Wolfram syndrome and systemic inflammation 102
Circulating levels of IL-10 are critically related to growth and rejection patterns of murine mastocytoma cells. 99
AhR-Mediated, Non-Genomic Modulation of IDO1 Function 99
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells 98
Ectopic expression of IL-35Ig by dendritic cells induces tolerance via Arginase 1. 95
Modulation of tryptophan catabolism by regulatory T cells 93
Effects of probiotic administration on immune responses of children and adolescents with type 1 diabetes to a quadrivalent inactivated influenza vaccine 93
Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication 91
IL-6 inhibits the tolerogenic function of CD8 alpha+ dendritic cells expressing indoleamine 2,3-dioxygenase. 90
Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ 89
High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway. 89
Effect of Probiotic Administration on Serum Tryptophan Metabolites in Pediatric Type 1 Diabetes Patients 88
Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymes. 87
Indoleamine 2,3-dioxygenase, transcriptional regulation and autoimmunity. 86
Crocus sativus L. Petal Extract Inhibits Inflammation and Osteoclastogenesis in RAW 264.7 Cell Model 86
The signaling function of IDO1 incites the malignant progression of mouse B16 melanoma 84
Reinstalling immune regulatory tryptophan catabolism in juvenile diabetes via interleukin 6 receptor blockade 84
Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12 84
Anti-inflammatory and anti-osteoclastogenic activity of a Crocus sativus petal extract targeting macrophages: from waste to raw material on the way to preventing bone loss. Maria 82
CD40 ligation prevents onset of tolerogenic properties in human dendritic cells treated with CTLA-4-Ig. 82
INDOLEAMINE 2,3-DIOXYGENASE 1 (IDO1) IS UPREGULATED IN THYROID CARCINOMA AND DRIVES THE DEVELOPMENT OF AN IMMUNOSUPPRESSANT TUMOR MICROENVIRONMENT. 81
T cell apoptosis by tryptophan catabolism 80
Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells. 80
Towards the identification of a tolerogenic signature in IDO-competent dendritic cells 79
Ectopic expression of IL-35Ig by dendritic cells induces IDO-related tolerance in vivo 79
Cutting edge: silencing suppressor of cytokine signaling 3 expression in dendritic cells turns CD28-Ig from immune adjuvant to suppressant. 79
Loss of IDO1 Expression From Human Pancreatic -Cells Precedes Their Destruction During the Development of Type 1 Diabetes 79
Human Indoleamine 2,3-dioxygenase 1 (IDO1) Expressed in Plant Cells Induces Kynurenine Production 78
Urinary l-kynurenine quantification and selective extraction through a molecularly imprinted solid-phase extraction device. 77
CTLA-4-Ig regulates tryptophan catabolism in vivo. 76
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice 76
Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells. 75
IL-23 and IL-12 have overlapping but distinct effects on murine dendritic cells. 73
IL-12 induces SDS-stable class II (alpha beta) dimers in murine dendritic cells 73
IL-13 Mediates In Vivo IL-9 Activities on Lung Epithelial Cells but Not on Hematopoietic Cells 73
Pathogenetic Interplay Between IL-6 and Tryptophan Metabolism in an Experimental Model of Obesity 73
The circadian control of tryptophan metabolism regulates the host response to pulmonary fungal infections 72
IL-12 ACTS DIRECTLY ON DC TO PROMOTE NUCLEAR LOCALIZATION OF NF-kB AND PRIMES DC FOR IL-12 PRODUCTION 72
Emulgel loaded with flaxseed extracts as new therapeutic approach in wound treatment 72
The catalytic inhibitor epacadostat can affect the non-enzymatic function of IDO1 71
Tryptophan catabolism generates autoimmune-preventive regulatory T cells 71
The Proteasome Inhibitor Bortezomib Controls Indoleamine 2,3-Dioxygenase 1 Breakdown and Restores Immune Regulation in Autoimmune Diabetes. 71
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells 71
Wolfram syndrome, a rare neurodegenerative disease: From pathogenesis to future treatment perspectives 71
Dendritic cells, CD4+ lymphocytes and IL-12 in an experimental model of antitumor immunotherapy 70
IL-22 is produced by γC-independent CD25+ CCR6+ innate murine spleen cells upon inflammatory stimuli and contributes to LPS-induced lethality. 70
Indoleamine 2,3-dioxygenase 1 (IDO1): an up-to-date overview of an eclectic immunoregulatory enzyme 69
SLC6A4 DNA Methylation Levels and Serum Kynurenine/Tryptophan Ratio in Eating Disorders: A Possible Link with Psychopathological Traits? 68
Functional plasticity of dendritic cell subsets as mediated by CD40 versus B7 activation. 68
SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis 67
Interleukin-9 induces 24P3 lipocalin gene expression in murine T cell lymphomas. 67
Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy 66
The role of TGF-beta as tolerogenic cytokine in regulating dendritic cell function. 66
Endotoxin tolerance as a novel defense strategy in infectious diseases: the role of tryptophan catabolism 65
Modulation of Indoleamine 2,3-Dioxygenase 1 During Inflammatory Bowel Disease Activity in Humans and Mice 64
Epacadostat stabilizes the apo-form of IDO1 and signals a pro-tumorigenic pathway in human ovarian cancer cells 64
Immunogenicity of tumor peptides: importance of peptide length and stability of peptide/MHC class II complex 64
Proteasomal Degradation of Indoleamine 2,3-Dioxygenase in CD8 Dendritic Cells is Mediated by Suppressor of Cytokine Signaling 3 (SOCS3). 64
Challenges in the design of reliable immuno-oncology mouse models to inform drug development 64
Totale 9.992
Categoria #
all - tutte 47.531
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 47.531


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021610 0 0 0 0 0 70 110 12 99 43 62 214
2021/20221.458 14 172 22 46 44 32 14 274 134 212 149 345
2022/20231.791 112 328 19 150 164 164 1 82 654 27 65 25
2023/2024880 50 107 29 15 15 9 222 16 82 25 126 184
2024/20252.031 28 153 100 146 213 114 131 225 335 104 304 178
2025/20262.454 259 284 260 634 592 425 0 0 0 0 0 0
Totale 10.933