ORABONA, Ciriana
 Distribuzione geografica
Continente #
NA - Nord America 4.789
EU - Europa 3.819
AS - Asia 3.609
SA - Sud America 534
AF - Africa 86
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 4
Totale 12.847
Nazione #
US - Stati Uniti d'America 4.659
SG - Singapore 1.641
IT - Italia 1.035
CN - Cina 521
IE - Irlanda 490
HK - Hong Kong 455
VN - Vietnam 425
BR - Brasile 407
RU - Federazione Russa 351
RO - Romania 315
DE - Germania 280
UA - Ucraina 276
FR - Francia 261
SE - Svezia 237
FI - Finlandia 151
GB - Regno Unito 120
IN - India 116
KR - Corea 77
BD - Bangladesh 66
CA - Canada 65
BE - Belgio 50
TR - Turchia 47
CZ - Repubblica Ceca 46
AR - Argentina 44
PL - Polonia 40
MX - Messico 39
NL - Olanda 39
AT - Austria 33
IQ - Iraq 30
JP - Giappone 30
PK - Pakistan 29
ES - Italia 26
ID - Indonesia 22
ZA - Sudafrica 22
CO - Colombia 21
IR - Iran 21
CH - Svizzera 20
GR - Grecia 19
EC - Ecuador 17
VE - Venezuela 17
SA - Arabia Saudita 16
PH - Filippine 15
UZ - Uzbekistan 15
MA - Marocco 13
CI - Costa d'Avorio 11
CL - Cile 9
JO - Giordania 9
LT - Lituania 9
AZ - Azerbaigian 8
LB - Libano 8
AE - Emirati Arabi Uniti 7
EG - Egitto 7
MY - Malesia 6
PE - Perù 6
TN - Tunisia 6
ET - Etiopia 5
EU - Europa 5
GT - Guatemala 5
KE - Kenya 5
KZ - Kazakistan 5
PY - Paraguay 5
UY - Uruguay 5
IL - Israele 4
OM - Oman 4
TH - Thailandia 4
AL - Albania 3
CR - Costa Rica 3
GE - Georgia 3
HU - Ungheria 3
JM - Giamaica 3
PA - Panama 3
PS - Palestinian Territory 3
AU - Australia 2
BG - Bulgaria 2
BH - Bahrain 2
BO - Bolivia 2
DK - Danimarca 2
DZ - Algeria 2
EE - Estonia 2
GA - Gabon 2
HN - Honduras 2
HR - Croazia 2
KG - Kirghizistan 2
KW - Kuwait 2
LK - Sri Lanka 2
MN - Mongolia 2
NG - Nigeria 2
NI - Nicaragua 2
NZ - Nuova Zelanda 2
RS - Serbia 2
YE - Yemen 2
AM - Armenia 1
AO - Angola 1
BB - Barbados 1
BT - Bhutan 1
BW - Botswana 1
BY - Bielorussia 1
BZ - Belize 1
CG - Congo 1
CU - Cuba 1
Totale 12.820
Città #
Singapore 1.250
Perugia 568
Chandler 534
Dublin 484
Hong Kong 450
San Jose 414
Ashburn 287
Bucharest 268
San Mateo 239
Boardman 198
Dong Ket 198
Santa Clara 184
Redmond 146
Jacksonville 144
Beijing 137
Moscow 130
Altamura 111
Munich 108
Medford 103
Wilmington 103
Princeton 101
Los Angeles 97
Ann Arbor 95
Lauterbourg 94
Lawrence 82
Ho Chi Minh City 80
Seoul 74
New York 73
The Dalles 70
Andover 65
Brussels 50
Hanoi 48
Council Bluffs 47
Dearborn 42
Des Moines 42
Falls Church 40
Orem 34
Turku 34
Helsinki 33
São Paulo 33
Chennai 32
Chicago 30
Piscataway 30
Saint Petersburg 29
Dallas 27
Denver 27
Warsaw 27
Montreal 26
Pisa 26
Brno 25
Woodbridge 25
Norwalk 24
Tokyo 24
Atlanta 22
Nuremberg 22
Rome 22
Izmir 21
Poplar 21
Boston 20
Redwood City 20
Vienna 20
Brooklyn 19
Frankfurt am Main 19
Fremont 18
Milan 18
Măgurele 18
Chiajna 17
Houston 17
Johannesburg 17
Manchester 17
Olomouc 17
San Paolo di Civitate 16
Stockholm 16
Guangzhou 14
Amsterdam 13
Columbus 13
Haiphong 13
Lappeenranta 13
London 13
Mexico City 13
Phoenix 13
Vicenza 13
Florence 12
Abidjan 11
San Francisco 11
Seattle 11
Shanghai 11
Baghdad 10
Lahore 10
Tashkent 10
Toronto 10
Belo Horizonte 9
Da Nang 9
Hefei 9
Jeddah 9
Medellín 9
Mumbai 9
Nanjing 9
Rio de Janeiro 9
San Diego 9
Totale 8.314
Nome #
Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3-dioxygenase1 227
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1 211
A GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune Suppression. 204
Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells 204
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells 200
Amino-acid sensing and degrading pathways in immune regulation 196
Aryl hydrocarbon receptor control of a disease tolerance defence pathway. 190
Distinct roles of immunoreceptor tyrosine-based motifs in immunosuppressive indoleamine 2,3-dioxygenase 1. 183
Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells 182
Advances in indoleamine 2,3-dioxygenase 1 medicinal chemistry 180
Amino acid metabolism as drug target in autoimmune diseases 179
Identification of a 2-propanol analogue modulating the non-enzymatic function of indoleamine 2,3-dioxygenase 1 175
Bioadhesive Polymeric Films Based on Red Onion Skins Extract for Wound Treatment: An Innovative and Eco-Friendly Formulation 164
Artocarpus tonkinensis extract inhibits LPS-triggered inflammation markers and suppresses RANKL-induced osteoclastogenesis in RAW264.7 164
IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII 161
87P - Towards the identification of the mechanism of action of antitumor 1-methyl-D-tryptophan 158
Fragment-based approach to identify IDO1 inhibitor building blocks 156
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation 155
IL‐35Ig–expressing dendritic cells induce tolerance via Arginase 1 154
A back-door insight into the modulation of Src kinase activity by the polyamine spermidine 148
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy 148
LPS-conditioned dendritic cells confer endotoxin tolerance contingent on tryptophan catabolism 145
Dendritic cells expressing ectopic IL-35Ig induce IDO-related tolerance in vivo. 144
Is It Time to Use Probiotics to Prevent or Treat Obesity? 144
A novel mutation of indoleamine 2,3-dioxygenase 1 causes a rapid proteasomal degradation and compromises protein function 144
Cutting edge: Autocrine TGF-beta sustains default tolerogenesis by IDO-competent dendritic cells. 142
Anti-osteoclastogenic activity of Crocus sativus petal extract: turning saffron waste into a valuable resource against bone disruption. 138
T cell apoptosis by kynurenines. 137
The TGF-β/IDO axis in infectious tolerance. 137
Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1 in juvenile diabetes 137
Tracking Hidden Binding Pockets Along the Molecular Recognition Path of l-Trp to Indoleamine 2,3-Dioxygenase 1 132
A novel metabotropic glutamate receptor 4 allosteric modulator effective in multiple sclerosis experimental autoimmune encephalomyelitis (EAE) mouse model 129
Aryl hydrocarbon Receptor and RelB control long term expression of Indoleamine 2,3-dioxygenase-1 in endotoxin tolerance 129
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86. 128
Antigen-specific immunoregulation by IL-35Ig-transfected dendritic cells 128
Integrated Fragment-Based Approaches on the Route to Novel IDO1 Modulators 128
Circulating levels of IL-10 are critically related to growth and rejection patterns of murine mastocytoma cells. 124
Forced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes 124
Preclinical discovery and development of fingolimod for the treatment of multiple sclerosis 122
Ectopic expression of IL-35Ig by dendritic cells induces tolerance via Arginase 1. 122
AhR-Mediated, Non-Genomic Modulation of IDO1 Function 121
Modulation of natriuretic peptide receptors in human adipose tissue: molecular mechanisms behind the “natriuretic handicap” in morbidly obese patients 121
Novel mutations in the WFS1 gene are associated with Wolfram syndrome and systemic inflammation 120
CD40 ligation prevents onset of tolerogenic properties in human dendritic cells treated with CTLA-4-Ig. 119
Different partners, opposite outcomes: A New Perspective of the Immunobiology of Indoleamine 2,3-Dioxygenase 118
Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication 117
CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice 117
Anti-inflammatory and anti-osteoclastogenic activity of a Crocus sativus petal extract targeting macrophages: from waste to raw material on the way to preventing bone loss. Maria 116
Effects of probiotic administration on immune responses of children and adolescents with type 1 diabetes to a quadrivalent inactivated influenza vaccine 115
Epacadostat stabilizes the apo-form of IDO1 and signals a pro-tumorigenic pathway in human ovarian cancer cells 110
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells 110
Effect of Probiotic Administration on Serum Tryptophan Metabolites in Pediatric Type 1 Diabetes Patients 110
Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ 109
Modulation of tryptophan catabolism by regulatory T cells 101
The catalytic inhibitor epacadostat can affect the non-enzymatic function of IDO1 100
Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymes. 100
Pathogenetic Interplay Between IL-6 and Tryptophan Metabolism in an Experimental Model of Obesity 100
Crocus sativus L. Petal Extract Inhibits Inflammation and Osteoclastogenesis in RAW 264.7 Cell Model 99
INDOLEAMINE 2,3-DIOXYGENASE 1 (IDO1) IS UPREGULATED IN THYROID CARCINOMA AND DRIVES THE DEVELOPMENT OF AN IMMUNOSUPPRESSANT TUMOR MICROENVIRONMENT. 98
Reinstalling immune regulatory tryptophan catabolism in juvenile diabetes via interleukin 6 receptor blockade 98
High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway. 98
The circadian control of tryptophan metabolism regulates the host response to pulmonary fungal infections 97
IL-6 inhibits the tolerogenic function of CD8 alpha+ dendritic cells expressing indoleamine 2,3-dioxygenase. 97
Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12 97
Cutting edge: silencing suppressor of cytokine signaling 3 expression in dendritic cells turns CD28-Ig from immune adjuvant to suppressant. 97
The signaling function of IDO1 incites the malignant progression of mouse B16 melanoma 96
T cell apoptosis by tryptophan catabolism 96
Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells. 96
Towards the identification of a tolerogenic signature in IDO-competent dendritic cells 96
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice 96
Human Indoleamine 2,3-dioxygenase 1 (IDO1) Expressed in Plant Cells Induces Kynurenine Production 94
Indoleamine 2,3-dioxygenase, transcriptional regulation and autoimmunity. 94
CTLA-4-Ig regulates tryptophan catabolism in vivo. 94
Loss of IDO1 Expression From Human Pancreatic -Cells Precedes Their Destruction During the Development of Type 1 Diabetes 94
Ectopic expression of IL-35Ig by dendritic cells induces IDO-related tolerance in vivo 93
Urinary l-kynurenine quantification and selective extraction through a molecularly imprinted solid-phase extraction device. 93
Positive regulatory role of IL-12 in macrophages and modulation by IFN-gamma 91
Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells. 91
Wolfram syndrome, a rare neurodegenerative disease: From pathogenesis to future treatment perspectives 90
IL-12 ACTS DIRECTLY ON DC TO PROMOTE NUCLEAR LOCALIZATION OF NF-kB AND PRIMES DC FOR IL-12 PRODUCTION 88
Membrane Localization and Phosphorylation of Indoleamine 2,3-Dioxygenase 2 (IDO2) in A549 Human Lung Adenocarcinoma Cells: First Steps in Exploring Its Signaling Function 86
Tryptophan catabolism generates autoimmune-preventive regulatory T cells 86
IL-12 induces SDS-stable class II (alpha beta) dimers in murine dendritic cells 86
IL-22 is produced by γC-independent CD25+ CCR6+ innate murine spleen cells upon inflammatory stimuli and contributes to LPS-induced lethality. 86
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells 86
Emulgel loaded with flaxseed extracts as new therapeutic approach in wound treatment 86
Indoleamine 2,3-dioxygenase 1 (IDO1): an up-to-date overview of an eclectic immunoregulatory enzyme 85
Functional plasticity of dendritic cell subsets as mediated by CD40 versus B7 activation. 85
The Proteasome Inhibitor Bortezomib Controls Indoleamine 2,3-Dioxygenase 1 Breakdown and Restores Immune Regulation in Autoimmune Diabetes. 85
The role of TGF-beta as tolerogenic cytokine in regulating dendritic cell function. 85
Modulation of Indoleamine 2,3-Dioxygenase 1 During Inflammatory Bowel Disease Activity in Humans and Mice 84
Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy 83
SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis 83
Interleukin-9 induces 24P3 lipocalin gene expression in murine T cell lymphomas. 83
IL-13 Mediates In Vivo IL-9 Activities on Lung Epithelial Cells but Not on Hematopoietic Cells 83
SLC6A4 DNA Methylation Levels and Serum Kynurenine/Tryptophan Ratio in Eating Disorders: A Possible Link with Psychopathological Traits? 82
Sensing of an HIV-1-Derived Single-Stranded RNA-Oligonucleotide Induces Arginase 1-Mediated Tolerance 82
IL-23 and IL-12 have overlapping but distinct effects on murine dendritic cells. 82
Proteasomal Degradation of Indoleamine 2,3-Dioxygenase in CD8 Dendritic Cells is Mediated by Suppressor of Cytokine Signaling 3 (SOCS3). 82
Dendritic cells, CD4+ lymphocytes and IL-12 in an experimental model of antitumor immunotherapy 80
Totale 12.040
Categoria #
all - tutte 55.237
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 55.237


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.458 14 172 22 46 44 32 14 274 134 212 149 345
2022/20231.791 112 328 19 150 164 164 1 82 654 27 65 25
2023/2024880 50 107 29 15 15 9 222 16 82 25 126 184
2024/20252.031 28 153 100 146 213 114 131 225 335 104 304 178
2025/20264.766 259 284 260 634 592 491 790 325 484 397 152 98
2026/202744 44 0 0 0 0 0 0 0 0 0 0 0
Totale 13.289