IRIS - Res&Arch Institutional Research Information System - Research & Archive

ORABONA, Ciriana
 Distribuzione geografica
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Continente #
NA - Nord America 2.560
EU - Europa 2.529
AS - Asia 624
AF - Africa 11
Continente sconosciuto - Info sul continente non disponibili 5
SA - Sud America 3
Totale 5.732
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Nazione #
US - Stati Uniti d'America 2.546
IT - Italia 714
IE - Irlanda 486
HK - Hong Kong 285
RO - Romania 270
UA - Ucraina 267
SE - Svezia 221
VN - Vietnam 198
FR - Francia 140
DE - Germania 111
CN - Cina 91
FI - Finlandia 83
RU - Federazione Russa 73
BE - Belgio 49
GB - Regno Unito 39
TR - Turchia 21
CH - Svizzera 17
GR - Grecia 17
AT - Austria 16
CA - Canada 12
IN - India 12
CI - Costa d'Avorio 11
NL - Olanda 11
PL - Polonia 9
EU - Europa 5
LB - Libano 5
UZ - Uzbekistan 4
CZ - Repubblica Ceca 3
BR - Brasile 2
JP - Giappone 2
MX - Messico 2
SA - Arabia Saudita 2
SG - Singapore 2
CL - Cile 1
ES - Italia 1
HU - Ungheria 1
IR - Iran 1
KR - Corea 1
LV - Lettonia 1
Totale 5.732
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Città #
Chandler 534
Dublin 481
Perugia 428
Hong Kong 284
Bucharest 268
San Mateo 239
Dong Ket 198
Redmond 146
Jacksonville 144
Altamura 111
Medford 103
Wilmington 103
Princeton 101
Ann Arbor 95
Lawrence 82
Beijing 69
Andover 65
Brussels 49
Dearborn 42
Des Moines 42
Falls Church 40
Boardman 29
Saint Petersburg 29
Pisa 26
Norwalk 24
Woodbridge 24
Izmir 20
Redwood City 20
Ashburn 19
Fremont 18
San Paolo di Civitate 16
Vienna 12
Abidjan 11
Helsinki 11
New York 10
San Diego 9
Houston 8
Den Haag 7
Auburn Hills 6
Hanover 6
Terni 6
Chicago 5
Kraków 5
Moscow 5
Ottawa 5
Rome 5
Spoleto 5
Fairfield 4
Florence 4
Nagpur 4
Nanjing 4
Winnipeg 4
Civitanova Marche 3
Falkenstein 3
Frankfurt Am Main 3
Kunming 3
L’Aquila 3
Menlo Park 3
Nichelino 3
Nürnberg 3
Paris 3
Saint Louis 3
Simi Valley 3
Toronto 3
Amsterdam 2
Boydton 2
Bragadiru 2
Chennai 2
Esslingen am Neckar 2
Jeddah 2
Kālpākkam 2
Lappeenranta 2
Los Angeles 2
Ludwigshafen 2
Macerata 2
Milan 2
Monreale 2
Ningbo 2
Planegg 2
Porto Torres 2
Pune 2
Rio De Janeiro 2
Romainville 2
San Jose 2
Shenyang 2
Silea 2
Tappahannock 2
Vicenza 2
Alghero 1
Assisi 1
Athens 1
Azcapotzalco 1
Baotou 1
Barcelona 1
Boston 1
Budapest 1
Cagliari 1
Carrollton 1
Castel Maggiore 1
Chengdu 1
Totale 4.081
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Nome #
Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3-dioxygenase1 165
Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells 131
Distinct roles of immunoreceptor tyrosine-based motifs in immunosuppressive indoleamine 2,3-dioxygenase 1. 123
A GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune Suppression. 116
Aryl hydrocarbon receptor control of a disease tolerance defence pathway. 114
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells 112
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1 111
Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells 105
Amino-acid sensing and degrading pathways in immune regulation 103
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy 102
IL‐35Ig–expressing dendritic cells induce tolerance via Arginase 1 100
Identification of a 2-propanol analogue modulating the non-enzymatic function of indoleamine 2,3-dioxygenase 1 97
T cell apoptosis by kynurenines. 96
Amino acid metabolism as drug target in autoimmune diseases 94
Advances in indoleamine 2,3-dioxygenase 1 medicinal chemistry 90
IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII 85
The TGF-β/IDO axis in infectious tolerance. 84
Fragment-based approach to identify IDO1 inhibitor building blocks 84
Forced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes 83
Is It Time to Use Probiotics to Prevent or Treat Obesity? 80
LPS-conditioned dendritic cells confer endotoxin tolerance contingent on tryptophan catabolism 80
Dendritic cells expressing ectopic IL-35Ig induce IDO-related tolerance in vivo. 79
Modulation of natriuretic peptide receptors in human adipose tissue: molecular mechanisms behind the “natriuretic handicap” in morbidly obese patients 78
CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice 76
Aryl hydrocarbon Receptor and RelB control long term expression of Indoleamine 2,3-dioxygenase-1 in endotoxin tolerance 75
87P - Towards the identification of the mechanism of action of antitumor 1-methyl-D-tryptophan 74
Artocarpus tonkinensis extract inhibits LPS-triggered inflammation markers and suppresses RANKL-induced osteoclastogenesis in RAW264.7 74
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells 72
A novel metabotropic glutamate receptor 4 allosteric modulator effective in multiple sclerosis experimental autoimmune encephalomyelitis (EAE) mouse model 70
Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1 in juvenile diabetes 70
Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ 69
Preclinical discovery and development of fingolimod for the treatment of multiple sclerosis 68
Cutting edge: Autocrine TGF-beta sustains default tolerogenesis by IDO-competent dendritic cells. 67
Bioadhesive Polymeric Films Based on Red Onion Skins Extract for Wound Treatment: An Innovative and Eco-Friendly Formulation 67
Antigen-specific immunoregulation by IL-35Ig-transfected dendritic cells 65
Modulation of tryptophan catabolism by regulatory T cells 64
Indoleamine 2,3-dioxygenase, transcriptional regulation and autoimmunity. 62
IL-6 inhibits the tolerogenic function of CD8 alpha+ dendritic cells expressing indoleamine 2,3-dioxygenase. 62
Different partners, opposite outcomes: A New Perspective of the Immunobiology of Indoleamine 2,3-Dioxygenase 62
Circulating levels of IL-10 are critically related to growth and rejection patterns of murine mastocytoma cells. 61
AhR-Mediated, Non-Genomic Modulation of IDO1 Function 61
High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway. 60
Tracking Hidden Binding Pockets Along the Molecular Recognition Path of l-Trp to Indoleamine 2,3-Dioxygenase 1 59
Ectopic expression of IL-35Ig by dendritic cells induces tolerance via Arginase 1. 58
Integrated Fragment-Based Approaches on the Route to Novel IDO1 Modulators 57
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86. 56
Reinstalling immune regulatory tryptophan catabolism in juvenile diabetes via interleukin 6 receptor blockade 53
A novel mutation of indoleamine 2,3-dioxygenase 1 causes a rapid proteasomal degradation and compromises protein function 53
Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymes. 51
Ectopic expression of IL-35Ig by dendritic cells induces IDO-related tolerance in vivo 51
T cell apoptosis by tryptophan catabolism 50
Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells. 48
Towards the identification of a tolerogenic signature in IDO-competent dendritic cells 48
CTLA-4-Ig regulates tryptophan catabolism in vivo. 47
INDOLEAMINE 2,3-DIOXYGENASE 1 (IDO1) IS UPREGULATED IN THYROID CARCINOMA AND DRIVES THE DEVELOPMENT OF AN IMMUNOSUPPRESSANT TUMOR MICROENVIRONMENT. 47
Novel mutations in the WFS1 gene are associated with Wolfram syndrome and systemic inflammation 46
IL-12 ACTS DIRECTLY ON DC TO PROMOTE NUCLEAR LOCALIZATION OF NF-kB AND PRIMES DC FOR IL-12 PRODUCTION 46
Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy 45
Dendritic cells, CD4+ lymphocytes and IL-12 in an experimental model of antitumor immunotherapy 44
Urinary l-kynurenine quantification and selective extraction through a molecularly imprinted solid-phase extraction device. 44
Challenges in the design of reliable immuno-oncology mouse models to inform drug development 43
CD40 ligation prevents onset of tolerogenic properties in human dendritic cells treated with CTLA-4-Ig. 43
Interleukin-9 induces 24P3 lipocalin gene expression in murine T cell lymphomas. 43
Loss of IDO1 Expression From Human Pancreatic -Cells Precedes Their Destruction During the Development of Type 1 Diabetes 43
Effects of probiotic administration on immune responses of children and adolescents with type 1 diabetes to a quadrivalent inactivated influenza vaccine 43
Functional plasticity of dendritic cell subsets as mediated by CD40 versus B7 activation. 42
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation 42
IL-22 is produced by γC-independent CD25+ CCR6+ innate murine spleen cells upon inflammatory stimuli and contributes to LPS-induced lethality. 41
Proteasomal Degradation of Indoleamine 2,3-Dioxygenase in CD8 Dendritic Cells is Mediated by Suppressor of Cytokine Signaling 3 (SOCS3). 41
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells 41
Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12 41
The role of TGF-beta as tolerogenic cytokine in regulating dendritic cell function. 40
Wolfram syndrome, a rare neurodegenerative disease: From pathogenesis to future treatment perspectives 40
IL-23 and IL-12 have overlapping but distinct effects on murine dendritic cells. 39
Cutting edge: silencing suppressor of cytokine signaling 3 expression in dendritic cells turns CD28-Ig from immune adjuvant to suppressant. 39
Anti-osteoclastogenic activity of Crocus sativus petal extract: turning saffron waste into a valuable resource against bone disruption. 39
Effect of Probiotic Administration on Serum Tryptophan Metabolites in Pediatric Type 1 Diabetes Patients 38
The Proteasome Inhibitor Bortezomib Controls Indoleamine 2,3-Dioxygenase 1 Breakdown and Restores Immune Regulation in Autoimmune Diabetes. 37
Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells. 36
Endotoxin tolerance as a novel defense strategy in infectious diseases: the role of tryptophan catabolism 36
SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis 35
Emulgel loaded with flaxseed extracts as new therapeutic approach in wound treatment 35
Crocus sativus L. Petal Extract Inhibits Inflammation and Osteoclastogenesis in RAW 264.7 Cell Model 35
Tryptophan catabolism generates autoimmune-preventive regulatory T cells 34
Immune system to brain signaling and vice versa: The role of tryptophan and glutamate 34
Immunogenicity of tumor peptides: importance of peptide length and stability of peptide/MHC class II complex 33
The p50 NF-kappa B subunit controls dendritic cell survival and immunogenicity 33
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice 33
Positive regulatory role of IL-12 in macrophages and modulation by IFN-gamma 32
TGF-beta and kynurenines as the key to infectious tolerance. 32
Immune Checkpoint Molecules, Personalized Immunotherapy, and Autoimmune Diabetes 32
Tryptophan catabolism in nonobese diabetic mice. 32
Indoleamine 2,3-dioxygenase: from catalyst to signaling function 31
Potential Benefits of Tryptophan Metabolism to the Efficacy of Tocilizumab in COVID-19 31
IL-12 induces SDS-stable class II (alpha beta) dimers in murine dendritic cells 29
The p50 Subunit of NF-κB Orchestrates Dendritic Cell Lifespan and Activation of Adaptive Immunity. 29
IL-13 Mediates In Vivo IL-9 Activities on Lung Epithelial Cells but Not on Hematopoietic Cells 28
Pathogenetic Interplay Between IL-6 and Tryptophan Metabolism in an Experimental Model of Obesity 27
PROTEASOME INHIBITION IN pDCs CONFERS AN IDO-DEPENDENT IMMUNOREGULATORY PHENOTYPE 23
The signaling function of IDO1 incites the malignant progression of mouse B16 melanoma 22
Totale 5.921
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Categoria #
all - tutte 20.257
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.257
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201943 0 0 0 0 0 0 0 0 0 6 28 9
2019/2020600 29 17 60 13 66 47 76 35 101 65 25 66
2020/20211.032 10 46 25 44 297 70 110 12 99 43 62 214
2021/20221.458 14 172 22 46 44 32 14 274 134 212 149 345
2022/20231.791 112 328 19 150 164 164 1 82 654 27 65 25
2023/2024563 50 107 29 15 15 9 229 16 86 7 0 0
Totale 6.131