ORABONA, Ciriana
 Distribuzione geografica
Continente #
NA - Nord America 4.605
EU - Europa 3.749
AS - Asia 3.540
SA - Sud America 530
AF - Africa 86
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 4
Totale 12.520
Nazione #
US - Stati Uniti d'America 4.489
SG - Singapore 1.625
IT - Italia 990
CN - Cina 505
IE - Irlanda 490
HK - Hong Kong 451
VN - Vietnam 425
BR - Brasile 404
RU - Federazione Russa 351
RO - Romania 310
UA - Ucraina 275
DE - Germania 273
FR - Francia 260
SE - Svezia 237
FI - Finlandia 151
GB - Regno Unito 120
IN - India 116
KR - Corea 77
CA - Canada 58
BE - Belgio 50
TR - Turchia 47
CZ - Repubblica Ceca 46
AR - Argentina 44
BD - Bangladesh 43
PL - Polonia 40
MX - Messico 37
NL - Olanda 35
AT - Austria 33
IQ - Iraq 30
JP - Giappone 30
PK - Pakistan 29
ID - Indonesia 22
ZA - Sudafrica 22
CO - Colombia 21
ES - Italia 21
CH - Svizzera 20
GR - Grecia 19
EC - Ecuador 17
VE - Venezuela 17
SA - Arabia Saudita 16
PH - Filippine 15
UZ - Uzbekistan 15
MA - Marocco 13
CI - Costa d'Avorio 11
IR - Iran 11
JO - Giordania 9
LT - Lituania 9
AZ - Azerbaigian 8
CL - Cile 8
LB - Libano 8
AE - Emirati Arabi Uniti 7
EG - Egitto 7
MY - Malesia 6
PE - Perù 6
TN - Tunisia 6
ET - Etiopia 5
EU - Europa 5
KE - Kenya 5
KZ - Kazakistan 5
PY - Paraguay 5
UY - Uruguay 5
GT - Guatemala 4
IL - Israele 4
OM - Oman 4
TH - Thailandia 4
AL - Albania 3
GE - Georgia 3
PA - Panama 3
PS - Palestinian Territory 3
AU - Australia 2
BG - Bulgaria 2
BH - Bahrain 2
BO - Bolivia 2
CR - Costa Rica 2
DK - Danimarca 2
DZ - Algeria 2
EE - Estonia 2
GA - Gabon 2
HN - Honduras 2
HR - Croazia 2
HU - Ungheria 2
JM - Giamaica 2
KG - Kirghizistan 2
KW - Kuwait 2
LK - Sri Lanka 2
MN - Mongolia 2
NG - Nigeria 2
NZ - Nuova Zelanda 2
RS - Serbia 2
YE - Yemen 2
AM - Armenia 1
AO - Angola 1
BT - Bhutan 1
BW - Botswana 1
BZ - Belize 1
CG - Congo 1
CU - Cuba 1
CY - Cipro 1
DJ - Gibuti 1
DO - Repubblica Dominicana 1
Totale 12.495
Città #
Singapore 1.244
Perugia 568
Chandler 534
Dublin 484
Hong Kong 446
San Jose 379
Ashburn 275
Bucharest 268
San Mateo 239
Dong Ket 198
Boardman 197
Santa Clara 173
Redmond 146
Jacksonville 144
Beijing 130
Moscow 130
Altamura 111
Munich 105
Medford 103
Wilmington 103
Princeton 101
Ann Arbor 95
Lauterbourg 94
Los Angeles 94
Lawrence 82
Ho Chi Minh City 80
Seoul 74
New York 70
The Dalles 69
Andover 65
Brussels 50
Hanoi 48
Council Bluffs 47
Dearborn 42
Des Moines 42
Falls Church 40
Orem 34
Turku 34
Helsinki 33
Chennai 32
São Paulo 32
Piscataway 29
Saint Petersburg 29
Warsaw 27
Chicago 26
Pisa 26
Brno 25
Denver 25
Woodbridge 25
Montreal 24
Norwalk 24
Tokyo 24
Dallas 23
Nuremberg 22
Izmir 21
Poplar 21
Rome 21
Atlanta 20
Redwood City 20
Vienna 20
Brooklyn 19
Frankfurt am Main 19
Boston 18
Fremont 18
Măgurele 18
Chiajna 17
Houston 17
Johannesburg 17
Manchester 17
Olomouc 17
Milan 16
San Paolo di Civitate 16
Stockholm 16
Guangzhou 14
Amsterdam 13
Columbus 13
Haiphong 13
Lappeenranta 13
London 13
Vicenza 13
Phoenix 12
Abidjan 11
Mexico City 11
San Francisco 11
Seattle 11
Shanghai 11
Baghdad 10
Lahore 10
Tashkent 10
Belo Horizonte 9
Da Nang 9
Florence 9
Hefei 9
Jeddah 9
Medellín 9
Mumbai 9
Nanjing 9
Rio de Janeiro 9
San Diego 9
Toronto 9
Totale 8.200
Nome #
Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3-dioxygenase1 226
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1 211
A GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune Suppression. 202
Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells 202
Amino-acid sensing and degrading pathways in immune regulation 194
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells 191
Aryl hydrocarbon receptor control of a disease tolerance defence pathway. 190
Distinct roles of immunoreceptor tyrosine-based motifs in immunosuppressive indoleamine 2,3-dioxygenase 1. 181
Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells 181
Amino acid metabolism as drug target in autoimmune diseases 178
Advances in indoleamine 2,3-dioxygenase 1 medicinal chemistry 176
Identification of a 2-propanol analogue modulating the non-enzymatic function of indoleamine 2,3-dioxygenase 1 173
IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII 161
87P - Towards the identification of the mechanism of action of antitumor 1-methyl-D-tryptophan 156
Fragment-based approach to identify IDO1 inhibitor building blocks 152
IL‐35Ig–expressing dendritic cells induce tolerance via Arginase 1 151
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation 150
Artocarpus tonkinensis extract inhibits LPS-triggered inflammation markers and suppresses RANKL-induced osteoclastogenesis in RAW264.7 150
A back-door insight into the modulation of Src kinase activity by the polyamine spermidine 147
Bioadhesive Polymeric Films Based on Red Onion Skins Extract for Wound Treatment: An Innovative and Eco-Friendly Formulation 147
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy 146
Is It Time to Use Probiotics to Prevent or Treat Obesity? 142
LPS-conditioned dendritic cells confer endotoxin tolerance contingent on tryptophan catabolism 142
Dendritic cells expressing ectopic IL-35Ig induce IDO-related tolerance in vivo. 141
A novel mutation of indoleamine 2,3-dioxygenase 1 causes a rapid proteasomal degradation and compromises protein function 141
Cutting edge: Autocrine TGF-beta sustains default tolerogenesis by IDO-competent dendritic cells. 139
T cell apoptosis by kynurenines. 137
The TGF-β/IDO axis in infectious tolerance. 134
Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1 in juvenile diabetes 134
Tracking Hidden Binding Pockets Along the Molecular Recognition Path of l-Trp to Indoleamine 2,3-Dioxygenase 1 130
Anti-osteoclastogenic activity of Crocus sativus petal extract: turning saffron waste into a valuable resource against bone disruption. 128
Aryl hydrocarbon Receptor and RelB control long term expression of Indoleamine 2,3-dioxygenase-1 in endotoxin tolerance 127
A novel metabotropic glutamate receptor 4 allosteric modulator effective in multiple sclerosis experimental autoimmune encephalomyelitis (EAE) mouse model 126
Integrated Fragment-Based Approaches on the Route to Novel IDO1 Modulators 126
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86. 125
Antigen-specific immunoregulation by IL-35Ig-transfected dendritic cells 125
Forced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes 123
Circulating levels of IL-10 are critically related to growth and rejection patterns of murine mastocytoma cells. 122
Preclinical discovery and development of fingolimod for the treatment of multiple sclerosis 121
AhR-Mediated, Non-Genomic Modulation of IDO1 Function 120
Modulation of natriuretic peptide receptors in human adipose tissue: molecular mechanisms behind the “natriuretic handicap” in morbidly obese patients 119
Ectopic expression of IL-35Ig by dendritic cells induces tolerance via Arginase 1. 119
Novel mutations in the WFS1 gene are associated with Wolfram syndrome and systemic inflammation 119
Different partners, opposite outcomes: A New Perspective of the Immunobiology of Indoleamine 2,3-Dioxygenase 118
CD40 ligation prevents onset of tolerogenic properties in human dendritic cells treated with CTLA-4-Ig. 117
CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice 116
Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication 114
Effects of probiotic administration on immune responses of children and adolescents with type 1 diabetes to a quadrivalent inactivated influenza vaccine 114
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells 110
Anti-inflammatory and anti-osteoclastogenic activity of a Crocus sativus petal extract targeting macrophages: from waste to raw material on the way to preventing bone loss. Maria 109
Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ 109
Effect of Probiotic Administration on Serum Tryptophan Metabolites in Pediatric Type 1 Diabetes Patients 106
Modulation of tryptophan catabolism by regulatory T cells 101
Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymes. 100
Reinstalling immune regulatory tryptophan catabolism in juvenile diabetes via interleukin 6 receptor blockade 97
Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12 97
IL-6 inhibits the tolerogenic function of CD8 alpha+ dendritic cells expressing indoleamine 2,3-dioxygenase. 96
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice 96
High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway. 96
Crocus sativus L. Petal Extract Inhibits Inflammation and Osteoclastogenesis in RAW 264.7 Cell Model 96
The catalytic inhibitor epacadostat can affect the non-enzymatic function of IDO1 95
Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells. 95
The signaling function of IDO1 incites the malignant progression of mouse B16 melanoma 94
Epacadostat stabilizes the apo-form of IDO1 and signals a pro-tumorigenic pathway in human ovarian cancer cells 94
Loss of IDO1 Expression From Human Pancreatic -Cells Precedes Their Destruction During the Development of Type 1 Diabetes 94
Indoleamine 2,3-dioxygenase, transcriptional regulation and autoimmunity. 93
Towards the identification of a tolerogenic signature in IDO-competent dendritic cells 93
INDOLEAMINE 2,3-DIOXYGENASE 1 (IDO1) IS UPREGULATED IN THYROID CARCINOMA AND DRIVES THE DEVELOPMENT OF AN IMMUNOSUPPRESSANT TUMOR MICROENVIRONMENT. 93
Cutting edge: silencing suppressor of cytokine signaling 3 expression in dendritic cells turns CD28-Ig from immune adjuvant to suppressant. 93
Human Indoleamine 2,3-dioxygenase 1 (IDO1) Expressed in Plant Cells Induces Kynurenine Production 92
CTLA-4-Ig regulates tryptophan catabolism in vivo. 92
T cell apoptosis by tryptophan catabolism 92
Urinary l-kynurenine quantification and selective extraction through a molecularly imprinted solid-phase extraction device. 92
The circadian control of tryptophan metabolism regulates the host response to pulmonary fungal infections 91
Ectopic expression of IL-35Ig by dendritic cells induces IDO-related tolerance in vivo 91
Pathogenetic Interplay Between IL-6 and Tryptophan Metabolism in an Experimental Model of Obesity 91
Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells. 89
Wolfram syndrome, a rare neurodegenerative disease: From pathogenesis to future treatment perspectives 88
Emulgel loaded with flaxseed extracts as new therapeutic approach in wound treatment 86
IL-12 induces SDS-stable class II (alpha beta) dimers in murine dendritic cells 85
IL-12 ACTS DIRECTLY ON DC TO PROMOTE NUCLEAR LOCALIZATION OF NF-kB AND PRIMES DC FOR IL-12 PRODUCTION 85
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells 84
Functional plasticity of dendritic cell subsets as mediated by CD40 versus B7 activation. 83
Tryptophan catabolism generates autoimmune-preventive regulatory T cells 83
IL-22 is produced by γC-independent CD25+ CCR6+ innate murine spleen cells upon inflammatory stimuli and contributes to LPS-induced lethality. 83
The role of TGF-beta as tolerogenic cytokine in regulating dendritic cell function. 83
IL-13 Mediates In Vivo IL-9 Activities on Lung Epithelial Cells but Not on Hematopoietic Cells 83
Indoleamine 2,3-dioxygenase 1 (IDO1): an up-to-date overview of an eclectic immunoregulatory enzyme 82
Modulation of Indoleamine 2,3-Dioxygenase 1 During Inflammatory Bowel Disease Activity in Humans and Mice 82
The Proteasome Inhibitor Bortezomib Controls Indoleamine 2,3-Dioxygenase 1 Breakdown and Restores Immune Regulation in Autoimmune Diabetes. 82
Membrane Localization and Phosphorylation of Indoleamine 2,3-Dioxygenase 2 (IDO2) in A549 Human Lung Adenocarcinoma Cells: First Steps in Exploring Its Signaling Function 81
Sensing of an HIV-1-Derived Single-Stranded RNA-Oligonucleotide Induces Arginase 1-Mediated Tolerance 81
IL-23 and IL-12 have overlapping but distinct effects on murine dendritic cells. 81
Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy 81
SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis 81
Interleukin-9 induces 24P3 lipocalin gene expression in murine T cell lymphomas. 81
Proteasomal Degradation of Indoleamine 2,3-Dioxygenase in CD8 Dendritic Cells is Mediated by Suppressor of Cytokine Signaling 3 (SOCS3). 80
SLC6A4 DNA Methylation Levels and Serum Kynurenine/Tryptophan Ratio in Eating Disorders: A Possible Link with Psychopathological Traits? 79
Dendritic cells, CD4+ lymphocytes and IL-12 in an experimental model of antitumor immunotherapy 79
Positive regulatory role of IL-12 in macrophages and modulation by IFN-gamma 79
Totale 11.763
Categoria #
all - tutte 51.407
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 51.407


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021319 0 0 0 0 0 0 0 0 0 43 62 214
2021/20221.458 14 172 22 46 44 32 14 274 134 212 149 345
2022/20231.791 112 328 19 150 164 164 1 82 654 27 65 25
2023/2024880 50 107 29 15 15 9 222 16 82 25 126 184
2024/20252.031 28 153 100 146 213 114 131 225 335 104 304 178
2025/20264.483 259 284 260 634 592 491 790 325 484 364 0 0
Totale 12.962