IRIS - Res&Arch Institutional Research Information System - Research & Archive

ORABONA, Ciriana
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 2.964
EU - Europa 2.612
AS - Asia 1.080
AF - Africa 14
Continente sconosciuto - Info sul continente non disponibili 5
SA - Sud America 3
OC - Oceania 1
Totale 6.679
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 2.948
IT - Italia 730
IE - Irlanda 486
SG - Singapore 378
HK - Hong Kong 280
RO - Romania 270
UA - Ucraina 267
SE - Svezia 221
VN - Vietnam 198
CN - Cina 162
FR - Francia 143
DE - Germania 127
FI - Finlandia 90
RU - Federazione Russa 73
BE - Belgio 49
CZ - Repubblica Ceca 42
GB - Regno Unito 41
TR - Turchia 21
CH - Svizzera 17
GR - Grecia 17
AT - Austria 16
CA - Canada 13
IN - India 13
KR - Corea 13
CI - Costa d'Avorio 11
NL - Olanda 11
PL - Polonia 9
EU - Europa 5
LB - Libano 5
UZ - Uzbekistan 4
MX - Messico 3
BR - Brasile 2
JP - Giappone 2
SA - Arabia Saudita 2
CL - Cile 1
EG - Egitto 1
ES - Italia 1
HU - Ungheria 1
IR - Iran 1
LV - Lettonia 1
MA - Marocco 1
NZ - Nuova Zelanda 1
QA - Qatar 1
SC - Seychelles 1
Totale 6.679
Salva come PNG Salva come JPEG
Città #
Chandler 534
Dublin 481
Perugia 425
Singapore 319
Hong Kong 278
Bucharest 268
San Mateo 239
Dong Ket 198
Boardman 197
Redmond 146
Jacksonville 144
Santa Clara 139
Altamura 111
Medford 103
Wilmington 103
Princeton 101
Ann Arbor 95
Lawrence 82
Beijing 69
Andover 65
Brussels 49
Dearborn 42
Des Moines 42
Falls Church 40
Saint Petersburg 29
Pisa 26
Brno 25
Ashburn 24
Norwalk 24
Woodbridge 24
Izmir 20
Los Angeles 20
Redwood City 20
Fremont 18
Helsinki 16
San Paolo di Civitate 16
Dallas 14
Olomouc 14
Munich 13
Vienna 12
Abidjan 11
Seoul 11
New York 10
San Diego 9
Houston 8
Chicago 7
Den Haag 7
Florence 7
Rome 7
Auburn Hills 6
Hanover 6
L’Aquila 6
Terni 6
Kraków 5
Macerata 5
Moscow 5
Ottawa 5
Spoleto 5
Boydton 4
Fairfield 4
Falkenstein 4
Nagpur 4
Nanjing 4
Paris 4
Shanghai 4
Winnipeg 4
Civitanova Marche 3
Frankfurt Am Main 3
Guangzhou 3
Kunming 3
Lappeenranta 3
Menlo Park 3
Nichelino 3
Nürnberg 3
Saint Louis 3
Simi Valley 3
Toronto 3
Amsterdam 2
Bragadiru 2
Chengdu 2
Chennai 2
Coalville 2
Esslingen am Neckar 2
Jeddah 2
Kālpākkam 2
Ludwigshafen 2
Milan 2
Monreale 2
Ningbo 2
Planegg 2
Porto Torres 2
Pune 2
Rio De Janeiro 2
Romainville 2
San Francisco 2
San Jose 2
Santarcangelo di Romagna 2
Shenyang 2
Silea 2
Tappahannock 2
Totale 4.822
Salva come PNG Salva come JPEG
Nome #
Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3-dioxygenase1 174
Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells 138
Distinct roles of immunoreceptor tyrosine-based motifs in immunosuppressive indoleamine 2,3-dioxygenase 1. 130
A GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune Suppression. 127
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1 127
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells 124
Aryl hydrocarbon receptor control of a disease tolerance defence pathway. 122
Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells 118
Amino-acid sensing and degrading pathways in immune regulation 116
Identification of a 2-propanol analogue modulating the non-enzymatic function of indoleamine 2,3-dioxygenase 1 109
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy 107
IL‐35Ig–expressing dendritic cells induce tolerance via Arginase 1 105
Amino acid metabolism as drug target in autoimmune diseases 104
T cell apoptosis by kynurenines. 103
Advances in indoleamine 2,3-dioxygenase 1 medicinal chemistry 101
IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII 95
Fragment-based approach to identify IDO1 inhibitor building blocks 92
Forced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes 91
Is It Time to Use Probiotics to Prevent or Treat Obesity? 89
LPS-conditioned dendritic cells confer endotoxin tolerance contingent on tryptophan catabolism 89
The TGF-β/IDO axis in infectious tolerance. 88
Dendritic cells expressing ectopic IL-35Ig induce IDO-related tolerance in vivo. 86
Modulation of natriuretic peptide receptors in human adipose tissue: molecular mechanisms behind the “natriuretic handicap” in morbidly obese patients 86
87P - Towards the identification of the mechanism of action of antitumor 1-methyl-D-tryptophan 86
Cutting edge: Autocrine TGF-beta sustains default tolerogenesis by IDO-competent dendritic cells. 84
Aryl hydrocarbon Receptor and RelB control long term expression of Indoleamine 2,3-dioxygenase-1 in endotoxin tolerance 84
Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1 in juvenile diabetes 83
Artocarpus tonkinensis extract inhibits LPS-triggered inflammation markers and suppresses RANKL-induced osteoclastogenesis in RAW264.7 81
CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice 80
Preclinical discovery and development of fingolimod for the treatment of multiple sclerosis 80
Bioadhesive Polymeric Films Based on Red Onion Skins Extract for Wound Treatment: An Innovative and Eco-Friendly Formulation 80
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells 78
A novel metabotropic glutamate receptor 4 allosteric modulator effective in multiple sclerosis experimental autoimmune encephalomyelitis (EAE) mouse model 78
Different partners, opposite outcomes: A New Perspective of the Immunobiology of Indoleamine 2,3-Dioxygenase 74
Antigen-specific immunoregulation by IL-35Ig-transfected dendritic cells 73
Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ 73
Tracking Hidden Binding Pockets Along the Molecular Recognition Path of l-Trp to Indoleamine 2,3-Dioxygenase 1 71
Circulating levels of IL-10 are critically related to growth and rejection patterns of murine mastocytoma cells. 70
AhR-Mediated, Non-Genomic Modulation of IDO1 Function 70
Modulation of tryptophan catabolism by regulatory T cells 69
Integrated Fragment-Based Approaches on the Route to Novel IDO1 Modulators 69
Ectopic expression of IL-35Ig by dendritic cells induces tolerance via Arginase 1. 69
Indoleamine 2,3-dioxygenase, transcriptional regulation and autoimmunity. 67
IL-6 inhibits the tolerogenic function of CD8 alpha+ dendritic cells expressing indoleamine 2,3-dioxygenase. 66
High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway. 66
A novel mutation of indoleamine 2,3-dioxygenase 1 causes a rapid proteasomal degradation and compromises protein function 65
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86. 62
INDOLEAMINE 2,3-DIOXYGENASE 1 (IDO1) IS UPREGULATED IN THYROID CARCINOMA AND DRIVES THE DEVELOPMENT OF AN IMMUNOSUPPRESSANT TUMOR MICROENVIRONMENT. 59
Novel mutations in the WFS1 gene are associated with Wolfram syndrome and systemic inflammation 59
Reinstalling immune regulatory tryptophan catabolism in juvenile diabetes via interleukin 6 receptor blockade 57
Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymes. 56
Anti-osteoclastogenic activity of Crocus sativus petal extract: turning saffron waste into a valuable resource against bone disruption. 56
T cell apoptosis by tryptophan catabolism 55
Ectopic expression of IL-35Ig by dendritic cells induces IDO-related tolerance in vivo 55
Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells. 53
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation 53
Effects of probiotic administration on immune responses of children and adolescents with type 1 diabetes to a quadrivalent inactivated influenza vaccine 53
CTLA-4-Ig regulates tryptophan catabolism in vivo. 52
Towards the identification of a tolerogenic signature in IDO-competent dendritic cells 52
Dendritic cells, CD4+ lymphocytes and IL-12 in an experimental model of antitumor immunotherapy 50
CD40 ligation prevents onset of tolerogenic properties in human dendritic cells treated with CTLA-4-Ig. 50
Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12 50
Urinary l-kynurenine quantification and selective extraction through a molecularly imprinted solid-phase extraction device. 50
IL-12 ACTS DIRECTLY ON DC TO PROMOTE NUCLEAR LOCALIZATION OF NF-kB AND PRIMES DC FOR IL-12 PRODUCTION 50
Functional plasticity of dendritic cell subsets as mediated by CD40 versus B7 activation. 49
Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy 49
Crocus sativus L. Petal Extract Inhibits Inflammation and Osteoclastogenesis in RAW 264.7 Cell Model 49
Challenges in the design of reliable immuno-oncology mouse models to inform drug development 48
Loss of IDO1 Expression From Human Pancreatic -Cells Precedes Their Destruction During the Development of Type 1 Diabetes 48
Wolfram syndrome, a rare neurodegenerative disease: From pathogenesis to future treatment perspectives 48
The Proteasome Inhibitor Bortezomib Controls Indoleamine 2,3-Dioxygenase 1 Breakdown and Restores Immune Regulation in Autoimmune Diabetes. 47
Interleukin-9 induces 24P3 lipocalin gene expression in murine T cell lymphomas. 47
The role of TGF-beta as tolerogenic cytokine in regulating dendritic cell function. 47
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells 46
Proteasomal Degradation of Indoleamine 2,3-Dioxygenase in CD8 Dendritic Cells is Mediated by Suppressor of Cytokine Signaling 3 (SOCS3). 45
Cutting edge: silencing suppressor of cytokine signaling 3 expression in dendritic cells turns CD28-Ig from immune adjuvant to suppressant. 45
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice 45
Effect of Probiotic Administration on Serum Tryptophan Metabolites in Pediatric Type 1 Diabetes Patients 45
Emulgel loaded with flaxseed extracts as new therapeutic approach in wound treatment 45
IL-22 is produced by γC-independent CD25+ CCR6+ innate murine spleen cells upon inflammatory stimuli and contributes to LPS-induced lethality. 44
Endotoxin tolerance as a novel defense strategy in infectious diseases: the role of tryptophan catabolism 44
IL-23 and IL-12 have overlapping but distinct effects on murine dendritic cells. 42
Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells. 40
IL-12 induces SDS-stable class II (alpha beta) dimers in murine dendritic cells 40
Immune system to brain signaling and vice versa: The role of tryptophan and glutamate 40
IL-13 Mediates In Vivo IL-9 Activities on Lung Epithelial Cells but Not on Hematopoietic Cells 40
SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis 39
Positive regulatory role of IL-12 in macrophages and modulation by IFN-gamma 38
Tryptophan catabolism generates autoimmune-preventive regulatory T cells 38
Immunogenicity of tumor peptides: importance of peptide length and stability of peptide/MHC class II complex 38
A back-door insight into the modulation of Src kinase activity by the polyamine spermidine 37
The signaling function of IDO1 incites the malignant progression of mouse B16 melanoma 37
The p50 NF-kappa B subunit controls dendritic cell survival and immunogenicity 37
Indoleamine 2,3-dioxygenase: from catalyst to signaling function 36
TGF-beta and kynurenines as the key to infectious tolerance. 36
Immune Checkpoint Molecules, Personalized Immunotherapy, and Autoimmune Diabetes 36
Tryptophan catabolism in nonobese diabetic mice. 36
Potential Benefits of Tryptophan Metabolism to the Efficacy of Tocilizumab in COVID-19 36
The p50 Subunit of NF-κB Orchestrates Dendritic Cell Lifespan and Activation of Adaptive Immunity. 34
Pathogenetic Interplay Between IL-6 and Tryptophan Metabolism in an Experimental Model of Obesity 34
Totale 6.714
Salva come PNG Salva come JPEG
Categoria #
all - tutte 28.685
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.685
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020481 0 0 0 0 66 47 76 35 101 65 25 66
2020/20211.032 10 46 25 44 297 70 110 12 99 43 62 214
2021/20221.458 14 172 22 46 44 32 14 274 134 212 149 345
2022/20231.791 112 328 19 150 164 164 1 82 654 27 65 25
2023/2024880 50 107 29 15 15 9 222 16 82 25 126 184
2024/2025634 28 153 100 146 207 0 0 0 0 0 0 0
Totale 7.082