IRIS - Res&Arch Institutional Research Information System - Research & Archive

CAROTTI, Andrea
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 2.629
EU - Europa 1.805
AS - Asia 767
AF - Africa 10
SA - Sud America 4
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 1
Totale 5.219
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 2.617
IE - Irlanda 500
IT - Italia 485
SG - Singapore 324
UA - Ucraina 220
HK - Hong Kong 193
CN - Cina 130
DE - Germania 122
FI - Finlandia 104
RU - Federazione Russa 81
SE - Svezia 81
FR - Francia 57
VN - Vietnam 52
GB - Regno Unito 38
PL - Polonia 32
KR - Corea 23
BE - Belgio 17
TR - Turchia 17
CH - Svizzera 15
CZ - Repubblica Ceca 15
NL - Olanda 11
AT - Austria 10
GR - Grecia 9
EG - Egitto 8
MX - Messico 8
UZ - Uzbekistan 8
IL - Israele 7
JP - Giappone 7
CA - Canada 4
ES - Italia 3
EU - Europa 3
BG - Bulgaria 2
BR - Brasile 2
CI - Costa d'Avorio 2
CL - Cile 2
PH - Filippine 2
AE - Emirati Arabi Uniti 1
AZ - Azerbaigian 1
HU - Ungheria 1
IN - India 1
LB - Libano 1
MD - Moldavia 1
NZ - Nuova Zelanda 1
PT - Portogallo 1
Totale 5.219
Salva come PNG Salva come JPEG
Città #
Dublin 500
Chandler 483
Singapore 247
San Mateo 222
Hong Kong 192
Perugia 184
Boardman 181
Santa Clara 159
Medford 116
Princeton 115
Altamura 109
Jacksonville 107
Wilmington 97
Lawrence 88
Ann Arbor 81
Andover 56
Redmond 56
Dong Ket 50
Beijing 48
Des Moines 36
Kraków 31
Ashburn 29
Munich 28
Saint Petersburg 28
Falls Church 26
Helsinki 20
Los Angeles 20
Seoul 19
San Paolo di Civitate 17
Izmir 16
Brussels 15
Norwalk 15
Mcallen 14
New York 14
Redwood City 14
Rome 14
Woodbridge 14
Spoleto 12
Milan 11
Dallas 10
Fremont 10
Bologna 9
Cairo 8
Moscow 8
Brno 6
Ness Ziona 6
Renton 6
Shanghai 6
Simi Valley 6
Tübingen 6
Frankfurt Am Main 5
Lappeenranta 5
Tokyo 5
Bracciano 4
Chicago 4
Florence 4
Houston 4
Hradec Králové 4
Lausanne 4
Macerata 4
Montefalco 4
Olomouc 4
San Giustino 4
Ternopil 4
Toronto 4
Vienna 4
Washington 4
Winston-Salem 4
Amsterdam 3
Cassino 3
Detroit 3
Groningen 3
Nagold 3
Palermo 3
Siena 3
Terni 3
Wear 3
Abidjan 2
Auburn Hills 2
Bellagio 2
Calcinaia 2
Coalville 2
Da Nang 2
Den Haag 2
Esslingen am Neckar 2
Fairfield 2
Falkenstein 2
Foligno 2
Fuzhou 2
Guangzhou 2
Hanover 2
Irapuato 2
Jesi 2
Livorno 2
Madrid 2
Nea Smyrni 2
Prato 2
Prineville 2
Quezon City 2
Shenzhen 2
Totale 3.713
Salva come PNG Salva come JPEG
Nome #
Computational studies in enantioselective liquid chromatography: Forty years of evolution in docking- and molecular dynamics-based simulations 120
One-pot, telescoped synthesis of N-aryl-5-aminopyrazoles from anilines in environmentally benign conditions 82
Application of the “inverted chirality columns approach” for the monitoring of asymmetric synthesis protocols 79
Tracking Hidden Binding Pockets Along the Molecular Recognition Path of l-Trp to Indoleamine 2,3-Dioxygenase 1 71
Ion pairing to enhance antibiotic drug efficacy. A new approach to fight problematic infections? 70
Integrated Fragment-Based Approaches on the Route to Novel IDO1 Modulators 69
Sequence variants in kynurenine aminotransferase II (KAT II) orthologs determine different potencies of the inhibitor S-ESBA 68
Asymmetric synthesis of the four diastereoisomers of a novel non-steroidal farnesoid X receptor (FXR) agonist: Role of the chirality on the biological activity 66
1μs Molecular Dynamics Simulations to study the poisoning effect of the PARP-1 full length enzyme 65
Binding properties of different categories of IDO1 inhibitors: A microscale thermophoresis study 65
Targeting the FXR nuclear receptor through a virtual screening approach 64
a-Amino-b-carboxymuconate-e-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of de Novo Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis 64
N-Decyl-S-trityl-(R)-cysteine, a new chiral selector for "green" ligand-exchange chromatography applications 64
Targeting the FXR Nuclear Receptor through a Virtual Screening Approach 62
An Integrated Approach to Ligand- and Structure-Based Drug Design: Development and Application to a Series of Serine Protease Inhibitors 61
Discovery and characterization of novel potent PARP-1 inhibitors endowed with neuroprotective properties: From TIQ-A to HYDAMTIQ 60
Chromatographic separation of free dafachronic acid epimers with a novel triazole click quinidine-based chiral stationary phase 60
Cyclopropyl Dafachronic Acid Stereoisomers as Conformationally Constrained DAF-12 Ligands 60
Successful rate gain by combination of multiple techniques 60
Fluorinated Benzyloxyphenyl Piperidine-4-carboxamides with Dual Function against Thrombosis: Inhibitors of Factor Xa and Platelet Aggregation 58
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy. 58
New Insights from Crystallographic Data: Diversity of Structural Motifs and Molecular Recognition Properties between Groups of IDO1 Structures 58
Beyond Bile Acids: Targeting Farnesoid X Receptor (FXR) with Natural and Synthetic Ligands 57
Expanding the horizon of chemotherapeutic targets: From MDM2 to MDMX (MDM4). 56
Structural Insights into Monoamine Oxidase Inhibitory Potency and Selectivity of 7-Substituted Coumarins from Ligand- and Target-Based Approaches 56
Elucidation of the chromatographic enantiomer elution order through computational studies 56
Mixed-mode chromatography characteristics of chiralpak ZWIX(+) and ZWIX(−) and elucidation of their chromatographic orthogonality for LC × LC application 56
Binding models of reversible inhibitors to type-B monoamine oxidase 55
Discovery of 3α,7α,11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid (TC-100), a Novel Bile Acid as Potent and Highly Selective FXR Agonist for Enterohepatic Disorders 55
The Janus-faced nature of IDO1 in infectious diseases: Challenges and therapeutic opportunities 54
Exploiting Chemical Toolboxes for the Expedited Generation of Tetracyclic Quinolines as a Novel Class of PXR Agonists 54
Quantum mechanics/molecular mechanics (QM/MM) modeling of the irreversible transamination of L-kynurenine to kynurenic acid: The round dance of kynurenine aminotransferase II 53
Hydrophilic interaction liquid chromatography of aminoglycoside antibiotics with a diol-type stationary phase 53
N-Aryl-5-aminopyrazole: A Versatile Architecture in Medicinal Chemistry 52
A Natural Prothrombin Mutant Reveals an Unexpected Influence of A-chain Structure on the Activity of Human {alpha}-Thrombin 51
Synthesis and monoamine oxidase inhibitory activity of new pyridazine-, pyrimidine- and 1,2,4-triazine-containing tricyclic derivatives 51
Targeting the conformational transitions of MDM2 and MDMX: insights into dissimilarities and similarities of p53 recognition. 51
4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP) 51
Improved chromatographic diastereoresolution of cyclopropyl dafachronic acid derivatives using chiral anion exchangers 51
Optimized one-pot derivatization and enantioseparation of cysteine: Application to the study of a dietary supplement 51
Targeting the conformational transitions of MDM2 and MDMX: Insights into key residues affecting p53 recognition 50
Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors 50
Fragment based drug design and diversity-oriented synthesis of carboxylic acid isosteres 50
Fragment-based Design of Zwitterionic, Strong Cation- and Weak Anion-Exchange Type Mixed-mode Liquid Chromatography Ligands and their Chromatographic Exploration 49
Recent advances in urea- and thiourea-containing compounds: focus on innovative approaches in medicinal chemistry and organic synthesis 49
New potent and selective FXR agonists: design, synthesis and modeling of norcholanylamine derivatives 48
Computational Modeling Overview and Evolution 48
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 48
Binding modes identification through molecular dynamic simulations: a case study with carnosine enantiomers and the Teicoplanin A2-2-based chiral stationary phase 48
Chiral mobile phase in ligand-exchange chromatography of amino acids: Exploring the copper(II) salt anion effect with a computational approach 47
Enantioselective HPLC analysis to assist the chemical exploration of chiral imidazolines 47
Estimating the hydrophobicity extent of molecular fragments using reversed‐phase liquid chromatography 46
Investigation on the Antiplatelet Activity of Pyrrolo[3,2-c]pyridine-Containing Compounds 46
Concepts and Molecular Aspects in the Polypharmacology of PARP-1 Inhibitors 46
Insights in the PARP1 poisoning effect 46
Critical Assessment of a Structure-Based Screening Campaign for IDO1 Inhibitors: Tips and Pitfalls 46
Molecular Doscking and High-Troughput Molecular Dynamics to Detect and Analyze the Binding Site Properties of DAF-12 Orthologs in Parasitic Nematodes 45
Design, synthesis, molecular modeling and biological activity of chenodeoxycholic acid carbamate derivatives as potent and selective FXR agonists 45
Pyrazole[3,4-e][1,4]thiazepin-7-one derivatives as a novel class of Farnesoid X Receptor (FXR) agonists 45
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome 45
Synthesis and biological evaluation of direct thrombin inhibitors bearing 4-(piperidin-1-yl)pyridine at the P1 position with potent anticoagulant activity. 44
Targeting the Conformational Transitions of MDM2 and MDMX. PART II: Insights into Key Residues Affecting p53 Recognition. 44
Synthesis, physicochemical properties, and biological activity of bile acids 3-glucuronides: Novel insights into bile acid signalling and detoxification 43
Discovery and Structure–Activity Relationships of Novel ssDAF-12 Receptor Modulators 42
Design, Synthesis, Crystallographic Studies and Preliminary Biological Appraisal of New Substituted Triazolo[4,3-b]pyridazin-8-amine Derivatives as Tankyrase Inhibitors. 42
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy 42
Reshaping antibiotics through hydrophobic drug-bile acid ionic complexation enhances activity against Staphylococcus aureus biofilms 42
Dissecting the allosteric FXR modulation: A chemical biology approach using guggulsterone as a chemical tool 42
HYDAMTIQ: A New, Potent PARP-1 Inhibitor with Neuroprotective Properties 41
Extending SAR of bile acids as FXR ligands: Discovery of 23-N-(carbocinnamyloxy)-3a,7a-dihydroxy-6a-ethyl-24-nor-5b-cholan-23-amine 41
High Affinity Central Benzodiazepine Receptor Ligands. Part 3: Insights into the Pharmacophore and Pattern Recognition Study of Intrinsic Activities of Pyrazolo[4,3-c]quinolin-3-ones 41
Targeting the Conformational Transitions of MDM2 and MDMX. PART I: Insights into Dissimilarities and Similarities of p53 Recognition 41
Docking Studies and Molecular Dynamic Simulations Reveal Different Features of IDO1 Structure 41
Integrating experimental and computational techniques to study chromatographic enantioresolutions of chiral tetrahydroindazole derivatives 41
Pyrazole[3,4-e][1,4]thiazepin-7-one Derivatives as a Novel Classo f Farnesoid X Receptor (FXR) Agonists 40
ENVIRONMENTALLY FRIENDLY, SEQUENTIAL, ONE-POT SYNTHESIS OF N-ARYL-5-AMINOPYRAZOLES FROM ANILINES 40
A rational approach to elucidate human monoamine oxidase molecular selectivity 40
Therapeutic Potential of a Novel Poly(ADP-ribose) Polymerase Inhibitor, Hydamtiq, in Human Pancreatic and Colon Cancers 40
Enantioseparation of novel anti-inflammatory chiral sulfoxides with two cellulose dichlorophenylcarbamate-based chiral stationary phases and polar-organic mobile phase(s) 40
Microsampling and enantioselective liquid chromatography coupled to mass spectrometry for chiral bioanalysis of novel psychoactive substances 39
Navigations of Chemical Space to Further the Understanding of Polypharmacology in Human Nuclear Receptors 39
Last ten years (2008–2018) of chiral ligand-exchange chromatography in HPLC: An updated review 39
The natural mutation by deletion of Lys9 in the thrombin A-chain affects the pKa value of catalytic residues, the overall enzyme’s stability and conformational transitions linked to Na+ binding 38
Enantioresolution, stereochemical characterization and biological activity of a chiral large-conductance calcium-activated potassium channel opener. 38
STUDY OF THE MICELLE FORMATION PROCESS OF BILE ACIDS THROUGHMOLECULAR DYAMICS SIMULATIONS 37
Natural and Synthetic Geiparvarins are Strong and Selective MAO-B Inhibitors. Synthesis and SAR Studies 37
Ester derivatives of annulated tetrahydroazocines: a new class of selective acetylcholinesterase inhibitors 37
Synthesis and Characterization of Chiral Iridium Complexes Bearing Carbohydrate Functionalized Pyridincarboxamide Ligands and Their Application as Catalysts in the Asymmetric Transfer Hydrogenation of α-Ketoacids in Water 36
Molecular Interaction Fields and 3D-QSAR Studies of p53-MDM2 Inhibitors Suggest Additional Features of Ligand-Target Interaction 36
Diastereo- and enantioseparation of a Nα-Boc amino acid with a zwitterionic quinine-based stationary phase: Focus on the stereorecognition mechanism 36
Enantioseparations by high-performance liquid chromatography based on chiral ligand exchange 36
Efficient enantioresolution of aromatic α-hydroxy acids with Cinchona alkaloid-based zwitterionic stationary phases and volatile polar-ionic eluents 36
Mechanistic investigations on a ligand-exchange system operating with a chiral mobile phase. 35
The effect of the Cu(II) salt anion in a ligand exchange system operating with a chiral mobile phase 34
Exploring the effect of PARP-1 flexibility in docking studies 34
Design, Synthesis, Crystallographic Studies, and Biological Appraisals of New Tankyrase Inhibitors. 34
Exploring the enantiorecognition mechanism of Cinchona alkaloid-based zwitterionic chiral stationary phases and the basic trans-paroxetine enantiomers 34
Lipophilicity-related inhibition of blood platelet aggregation by nipecotic acid anilides 33
From polypharmacology to target specificity: the case of PARP inhibitors. 33
Effects of Molecular Dynamics and Replica Exchange Molecular Dynamics in Sampling the Conformational Space of PARP-1 33
Totale 4.932
Salva come PNG Salva come JPEG
Categoria #
all - tutte 26.635
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 26.635
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020299 0 0 0 0 47 7 45 9 48 94 28 21
2020/2021639 6 38 10 31 240 36 54 31 84 15 34 60
2021/2022823 15 132 6 21 15 16 22 285 26 57 96 132
2022/20231.714 126 311 26 124 123 187 7 88 624 17 67 14
2023/2024803 55 106 40 12 11 15 156 29 82 33 120 144
2024/2025654 39 193 122 79 221 0 0 0 0 0 0 0
Totale 5.665