IRIS - Res&Arch Institutional Research Information System - Research & Archive

CAROTTI, Andrea
 Distribuzione geografica
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Continente #
NA - Nord America 5.595
AS - Asia 3.490
EU - Europa 3.018
SA - Sud America 571
Continente sconosciuto - Info sul continente non disponibili 524
AF - Africa 101
OC - Oceania 6
Totale 13.305
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Nazione #
US - Stati Uniti d'America 5.326
SG - Singapore 1.687
IT - Italia 849
CN - Cina 527
IE - Irlanda 501
BR - Brasile 431
HK - Hong Kong 429
RU - Federazione Russa 422
VN - Vietnam 253
UA - Ucraina 236
DE - Germania 215
FR - Francia 196
FI - Finlandia 142
GB - Regno Unito 124
CA - Canada 114
BD - Bangladesh 104
IN - India 98
SE - Svezia 97
KR - Corea 94
PL - Polonia 60
AR - Argentina 59
MX - Messico 43
TR - Turchia 42
JP - Giappone 36
NL - Olanda 32
UZ - Uzbekistan 28
ZA - Sudafrica 27
ID - Indonesia 26
CO - Colombia 21
CH - Svizzera 20
CZ - Repubblica Ceca 20
IL - Israele 20
BE - Belgio 19
IQ - Iraq 19
AT - Austria 17
EC - Ecuador 17
ES - Italia 17
CR - Costa Rica 16
EG - Egitto 15
GT - Guatemala 15
JO - Giordania 15
PH - Filippine 15
SA - Arabia Saudita 15
TT - Trinidad e Tobago 13
VE - Venezuela 13
JM - Giamaica 12
SV - El Salvador 12
MA - Marocco 11
NP - Nepal 11
TN - Tunisia 11
AE - Emirati Arabi Uniti 10
CL - Cile 10
CW - ???statistics.table.value.countryCode.CW??? 10
HN - Honduras 10
PK - Pakistan 10
GR - Grecia 9
LT - Lituania 9
NI - Nicaragua 9
PR - Porto Rico 9
PY - Paraguay 9
KZ - Kazakistan 8
MY - Malesia 8
DZ - Algeria 7
PE - Perù 6
SC - Seychelles 6
AZ - Azerbaigian 5
DO - Repubblica Dominicana 5
AM - Armenia 4
ET - Etiopia 4
LB - Libano 4
RO - Romania 4
AL - Albania 3
AU - Australia 3
BB - Barbados 3
CI - Costa d'Avorio 3
EU - Europa 3
GP - Guadalupe 3
MD - Moldavia 3
OM - Oman 3
RS - Serbia 3
TH - Thailandia 3
BF - Burkina Faso 2
BG - Bulgaria 2
DK - Danimarca 2
EE - Estonia 2
GE - Georgia 2
HU - Ungheria 2
KE - Kenya 2
KG - Kirghizistan 2
LA - Repubblica Popolare Democratica del Laos 2
LY - Libia 2
ME - Montenegro 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
SN - Senegal 2
UY - Uruguay 2
AF - Afghanistan, Repubblica islamica di 1
AG - Antigua e Barbuda 1
AO - Angola 1
Totale 12.763
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Città #
Singapore 1.209
Ashburn 627
San Jose 551
Dublin 501
Chandler 483
Hong Kong 423
Perugia 292
Santa Clara 246
San Mateo 222
Boardman 181
Council Bluffs 167
Moscow 142
Beijing 137
Lauterbourg 122
Princeton 120
Medford 116
Altamura 109
Jacksonville 108
Wilmington 97
Los Angeles 91
Munich 91
Seoul 90
Lawrence 88
New York 85
Ann Arbor 81
Ho Chi Minh City 70
Dallas 67
Andover 56
Redmond 56
Dong Ket 50
Hanoi 50
São Paulo 50
The Dalles 46
Rome 45
Phoenix 42
Des Moines 39
Montreal 35
North Bergen 34
Piscataway 34
Helsinki 31
Kraków 31
Chennai 30
Tokyo 30
Saint Petersburg 28
Falls Church 27
Warsaw 27
Orem 25
Brooklyn 24
Chicago 24
Toronto 24
Turku 22
Milan 21
Izmir 18
Shanghai 18
Tashkent 18
Buffalo 17
San Paolo di Civitate 17
Atlanta 16
Brussels 16
Houston 16
Mexico City 16
Johannesburg 15
Norwalk 15
Woodbridge 15
Boston 14
Denver 14
London 14
Mcallen 14
Redwood City 14
Stockholm 14
Manchester 13
Naples 13
Rio de Janeiro 13
Amman 12
Amsterdam 12
Bologna 12
Charlotte 12
Columbus 12
Guatemala City 12
Haiphong 12
New Delhi 12
Nuremberg 12
Spoleto 12
Brasília 11
Cairo 11
Poplar 11
San José 11
Ankara 10
Baghdad 10
Fremont 10
Hefei 10
Lappeenranta 10
Palermo 10
Turin 10
Willemstad 10
Campinas 9
Frankfurt am Main 9
Guangzhou 9
Guarulhos 9
Macerata 9
Totale 8.006
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Nome #
Discovery and Structure–Activity Relationships of Novel ssDAF-12 Receptor Modulators 186
Computational studies in enantioselective liquid chromatography: Forty years of evolution in docking- and molecular dynamics-based simulations 180
Integrated Fragment-Based Approaches on the Route to Novel IDO1 Modulators 155
Application of the “inverted chirality columns approach” for the monitoring of asymmetric synthesis protocols 153
Enantioselective HPLC analysis to assist the chemical exploration of chiral imidazolines 147
Tracking Hidden Binding Pockets Along the Molecular Recognition Path of l-Trp to Indoleamine 2,3-Dioxygenase 1 142
Critical Assessment of a Structure-Based Screening Campaign for IDO1 Inhibitors: Tips and Pitfalls 142
1μs Molecular Dynamics Simulations to study the poisoning effect of the PARP-1 full length enzyme 140
a-Amino-b-carboxymuconate-e-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of de Novo Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis 139
Chiral mobile phase in ligand-exchange chromatography of amino acids: Exploring the copper(II) salt anion effect with a computational approach 138
N-Decyl-S-trityl-(R)-cysteine, a new chiral selector for "green" ligand-exchange chromatography applications 137
New Insights from Crystallographic Data: Diversity of Structural Motifs and Molecular Recognition Properties between Groups of IDO1 Structures 133
One-pot, telescoped synthesis of N-aryl-5-aminopyrazoles from anilines in environmentally benign conditions 131
Binding properties of different categories of IDO1 inhibitors: A microscale thermophoresis study 130
Optimized one-pot derivatization and enantioseparation of cysteine: Application to the study of a dietary supplement 129
Asymmetric synthesis of the four diastereoisomers of a novel non-steroidal farnesoid X receptor (FXR) agonist: Role of the chirality on the biological activity 128
Cyclopropyl Dafachronic Acid Stereoisomers as Conformationally Constrained DAF-12 Ligands 128
An Integrated Approach to Ligand- and Structure-Based Drug Design: Development and Application to a Series of Serine Protease Inhibitors 126
Targeting the FXR nuclear receptor through a virtual screening approach 126
Exploiting Chemical Toolboxes for the Expedited Generation of Tetracyclic Quinolines as a Novel Class of PXR Agonists 126
Ion pairing to enhance antibiotic drug efficacy. A new approach to fight problematic infections? 124
Fragment-based Design of Zwitterionic, Strong Cation- and Weak Anion-Exchange Type Mixed-mode Liquid Chromatography Ligands and their Chromatographic Exploration 122
Turning a Tumor Microenvironment Pitfall into Opportunity: Discovery of Benzamidoxime as PD-L1 Ligand with pH-Dependent Potency 121
Estimating the hydrophobicity extent of molecular fragments using reversed‐phase liquid chromatography 118
Structural Insights into Monoamine Oxidase Inhibitory Potency and Selectivity of 7-Substituted Coumarins from Ligand- and Target-Based Approaches 118
Successful rate gain by combination of multiple techniques 118
Binding models of reversible inhibitors to type-B monoamine oxidase 116
Beyond Bile Acids: Targeting Farnesoid X Receptor (FXR) with Natural and Synthetic Ligands 116
Elucidation of the chromatographic enantiomer elution order through computational studies 115
Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors 115
Fragment based drug design and diversity-oriented synthesis of carboxylic acid isosteres 115
4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP) 114
Improved chromatographic diastereoresolution of cyclopropyl dafachronic acid derivatives using chiral anion exchangers 114
Mixed-mode chromatography characteristics of chiralpak ZWIX(+) and ZWIX(−) and elucidation of their chromatographic orthogonality for LC × LC application 114
Binding modes identification through molecular dynamic simulations: a case study with carnosine enantiomers and the Teicoplanin A2-2-based chiral stationary phase 113
Computational Modeling Overview and Evolution 112
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy. 111
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 111
The Janus-faced nature of IDO1 in infectious diseases: Challenges and therapeutic opportunities 110
Sequence variants in kynurenine aminotransferase II (KAT II) orthologs determine different potencies of the inhibitor S-ESBA 110
Effects of Molecular Dynamics and Replica Exchange Molecular Dynamics in Sampling the Conformational Space of PARP-1 109
Hydrophilic interaction liquid chromatography of aminoglycoside antibiotics with a diol-type stationary phase 109
Targeting the Conformational Transitions of MDM2 and MDMX. PART I: Insights into Dissimilarities and Similarities of p53 Recognition 108
Atypical enantioseparation of a non-ionic form of allantoin with Cinchona alkaloid-based zwitterionic chiral stationary phases 107
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy 107
Integrating experimental and computational techniques to study chromatographic enantioresolutions of chiral tetrahydroindazole derivatives 107
Recent advances in urea- and thiourea-containing compounds: focus on innovative approaches in medicinal chemistry and organic synthesis 107
Insights in the PARP1 poisoning effect 105
Targeting the Conformational Transitions of MDM2 and MDMX. PART II: Insights into Key Residues Affecting p53 Recognition. 103
Discovery of 3α,7α,11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid (TC-100), a Novel Bile Acid as Potent and Highly Selective FXR Agonist for Enterohepatic Disorders 103
Microsampling and enantioselective liquid chromatography coupled to mass spectrometry for chiral bioanalysis of novel psychoactive substances 102
Synthesis and Characterization of Chiral Iridium Complexes Bearing Carbohydrate Functionalized Pyridincarboxamide Ligands and Their Application as Catalysts in the Asymmetric Transfer Hydrogenation of α-Ketoacids in Water 102
A Natural Prothrombin Mutant Reveals an Unexpected Influence of A-chain Structure on the Activity of Human {alpha}-Thrombin 102
Chromatographic separation of free dafachronic acid epimers with a novel triazole click quinidine-based chiral stationary phase 102
N-Aryl-5-aminopyrazole: A Versatile Architecture in Medicinal Chemistry 102
Dissecting the allosteric FXR modulation: A chemical biology approach using guggulsterone as a chemical tool 101
A journey in unraveling the enantiorecognition mechanism of 3,5-dinitrobenzoyl-amino acids with two Cinchona alkaloid-based chiral stationary phases: The power of molecular dynamic simulations 100
Expanding the horizon of chemotherapeutic targets: From MDM2 to MDMX (MDM4). 100
Discovery and characterization of novel potent PARP-1 inhibitors endowed with neuroprotective properties: From TIQ-A to HYDAMTIQ 100
Docking Studies and Molecular Dynamic Simulations Reveal Different Features of IDO1 Structure 100
Design, synthesis, molecular modeling and biological activity of chenodeoxycholic acid carbamate derivatives as potent and selective FXR agonists 99
Targeting the conformational transitions of MDM2 and MDMX: insights into dissimilarities and similarities of p53 recognition. 97
Reshaping antibiotics through hydrophobic drug-bile acid ionic complexation enhances activity against Staphylococcus aureus biofilms 97
Structural Basis of Human Dimeric α-Amino-β-Carboxymuconate-ε-Semialdehyde Decarboxylase Inhibition With TES-1025 97
Quantum mechanics/molecular mechanics (QM/MM) modeling of the irreversible transamination of L-kynurenine to kynurenic acid: The round dance of kynurenine aminotransferase II 96
Concepts and Molecular Aspects in the Polypharmacology of PARP-1 Inhibitors 96
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome 96
Synthesis, physicochemical properties, and biological activity of bile acids 3-glucuronides: Novel insights into bile acid signalling and detoxification 95
Last ten years (2008–2018) of chiral ligand-exchange chromatography in HPLC: An updated review 95
Fluorinated Benzyloxyphenyl Piperidine-4-carboxamides with Dual Function against Thrombosis: Inhibitors of Factor Xa and Platelet Aggregation 94
Multiple Heart-Cutting Two-Dimensional HPLC-UV Achiral–Chiral Analysis of Branched-Chain Amino Acids in Food Supplements under Environmentally Friendly Conditions 92
Environmentally Sustainable Achiral and Chiral Chromatographic Analysis of Amino Acids in Food Supplements 92
Synthesis and monoamine oxidase inhibitory activity of new pyridazine-, pyrimidine- and 1,2,4-triazine-containing tricyclic derivatives 92
Enantioseparation of novel anti-inflammatory chiral sulfoxides with two cellulose dichlorophenylcarbamate-based chiral stationary phases and polar-organic mobile phase(s) 92
Molecular Dynamics-Ensemble Docking and Biophysical Studies for Structure-Based Identification of Non-Amino Acidic Ligands of DDAH-1 90
Targeting the conformational transitions of MDM2 and MDMX: Insights into key residues affecting p53 recognition 90
Targeting the FXR Nuclear Receptor through a Virtual Screening Approach 90
ENVIRONMENTALLY FRIENDLY, SEQUENTIAL, ONE-POT SYNTHESIS OF N-ARYL-5-AMINOPYRAZOLES FROM ANILINES 89
Efficient enantioresolution of aromatic α-hydroxy acids with Cinchona alkaloid-based zwitterionic stationary phases and volatile polar-ionic eluents 89
New potent and selective FXR agonists: design, synthesis and modeling of norcholanylamine derivatives 88
Chemical exploration of TGR5 functional hot-spots: Synthesis and structure-activity relationships of C7- and C23-Substituted cholic acid derivatives 87
Design, Synthesis, Crystallographic Studies and Preliminary Biological Appraisal of New Substituted Triazolo[4,3-b]pyridazin-8-amine Derivatives as Tankyrase Inhibitors. 87
Discovery of Novel 5-Lipoxygenase-Activating Protein (FLAP) Inhibitors by Exploiting a Multistep Virtual Screening Protocol 87
Synthesis and biological activity of cyclopropyl Δ7-dafachronic acids as DAF-12 receptor ligands 87
Synthesis and biological evaluation of direct thrombin inhibitors bearing 4-(piperidin-1-yl)pyridine at the P1 position with potent anticoagulant activity. 86
A rational approach to elucidate human monoamine oxidase molecular selectivity 86
Chiral high-performance liquid chromatography analysis of mono-, di-, and triacylglycerols with amylose- and cellulose-phenylcarbamate-based stationary phases 85
HYDAMTIQ: A New, Potent PARP-1 Inhibitor with Neuroprotective Properties 84
The "racemic approach" in the evaluation of the enantiomeric NorA efflux pump inhibition activity of 2-phenylquinoline derivatives 84
PHARMACOINFORMATICS IN DRUG R&D PROCESS 83
Pyrazole[3,4-e][1,4]thiazepin-7-one derivatives as a novel class of Farnesoid X Receptor (FXR) agonists 82
Enantioseparations by high-performance liquid chromatography based on chiral ligand exchange 82
Elucidation of retention mechanism of dipeptides on a ristocetin A-based chiral stationary phase using a combination of chromatographic and molecular simulation techniques 82
Extending SAR of bile acids as FXR ligands: Discovery of 23-N-(carbocinnamyloxy)-3a,7a-dihydroxy-6a-ethyl-24-nor-5b-cholan-23-amine 81
Exploring the effect of PARP-1 flexibility in docking studies 80
Therapeutic Potential of a Novel Poly(ADP-ribose) Polymerase Inhibitor, Hydamtiq, in Human Pancreatic and Colon Cancers 80
Chromatographic enantioresolution and stereochemical characterization of synthetic cannabinoid receptor agonists with Whelk-O®1 chiral stationary phases under mass spectrometry compatible reversed-phase conditions: A study case with seized samples 79
Diastereo- and enantioseparation of a Nα-Boc amino acid with a zwitterionic quinine-based stationary phase: Focus on the stereorecognition mechanism 79
Investigation on the Antiplatelet Activity of Pyrrolo[3,2-c]pyridine-Containing Compounds 77
Natural and Synthetic Geiparvarins are Strong and Selective MAO-B Inhibitors. Synthesis and SAR Studies 76
Totale 10.719
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Categoria #
all - tutte 60.557
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 60.557
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022649 0 0 0 0 15 16 22 285 26 57 96 132
2022/20231.714 126 311 26 124 123 187 7 88 624 17 67 14
2023/2024803 55 106 40 12 11 15 156 29 82 33 120 144
2024/20252.080 39 193 122 79 246 144 146 96 413 133 320 149
2025/20264.529 298 343 236 536 617 400 791 253 435 366 162 92
2026/20271.685 96 162 317 990 120 0 0 0 0 0 0 0
Totale 13.305