IRIS - Res&Arch Institutional Research Information System - Research & Archive

CAROTTI, Andrea
 Distribuzione geografica
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Continente #
NA - Nord America 2.216
EU - Europa 1.725
AS - Asia 354
AF - Africa 8
SA - Sud America 4
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 1
Totale 4.311
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Nazione #
US - Stati Uniti d'America 2.209
IE - Irlanda 500
IT - Italia 463
UA - Ucraina 219
HK - Hong Kong 193
FI - Finlandia 103
DE - Germania 93
RU - Federazione Russa 81
SE - Svezia 81
CN - Cina 61
FR - Francia 54
VN - Vietnam 52
GB - Regno Unito 34
PL - Polonia 31
BE - Belgio 17
TR - Turchia 17
CH - Svizzera 15
NL - Olanda 10
GR - Grecia 9
AT - Austria 8
EG - Egitto 8
UZ - Uzbekistan 8
IL - Israele 7
JP - Giappone 7
CA - Canada 4
EU - Europa 3
KR - Corea 3
MX - Messico 3
BG - Bulgaria 2
BR - Brasile 2
CL - Cile 2
SG - Singapore 2
AE - Emirati Arabi Uniti 1
AZ - Azerbaigian 1
CZ - Repubblica Ceca 1
ES - Italia 1
HU - Ungheria 1
IN - India 1
LB - Libano 1
MD - Moldavia 1
NZ - Nuova Zelanda 1
PT - Portogallo 1
Totale 4.311
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Città #
Dublin 500
Chandler 483
San Mateo 222
Hong Kong 192
Perugia 173
Medford 116
Princeton 115
Altamura 109
Jacksonville 107
Wilmington 97
Lawrence 88
Ann Arbor 81
Andover 56
Redmond 56
Dong Ket 50
Beijing 48
Des Moines 36
Kraków 31
Saint Petersburg 28
Falls Church 26
Boardman 21
Helsinki 20
Los Angeles 19
San Paolo di Civitate 17
Izmir 16
Brussels 15
Norwalk 15
Mcallen 14
New York 14
Redwood City 14
Rome 14
Woodbridge 14
Ashburn 12
Spoleto 12
Fremont 10
Milan 10
Bologna 9
Cairo 8
Moscow 8
Ness Ziona 6
Renton 6
Simi Valley 6
Tübingen 6
Frankfurt Am Main 5
Tokyo 5
Bracciano 4
Chicago 4
Florence 4
Houston 4
Lappeenranta 4
Lausanne 4
Macerata 4
Montefalco 4
San Giustino 4
Ternopil 4
Toronto 4
Winston-Salem 4
Cassino 3
Detroit 3
Groningen 3
Nagold 3
Palermo 3
Terni 3
Wear 3
Amsterdam 2
Auburn Hills 2
Bellagio 2
Calcinaia 2
Da Nang 2
Den Haag 2
Esslingen am Neckar 2
Fairfield 2
Falkenstein 2
Foligno 2
Fuzhou 2
Guangzhou 2
Hanover 2
Irapuato 2
Jesi 2
Nea Smyrni 2
Prato 2
Shanghai 2
Shenzhen 2
The Hague 2
Vienna 2
Zola Predosa 2
Aguascalientes 1
Auckland 1
Barcelona 1
Boydton 1
Brescia 1
Cambridge 1
Charleston 1
Chisinau 1
Collazzone 1
Costa Mesa 1
Costabissara 1
Cupertino 1
Dearborn 1
Denver 1
Totale 3.037
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Nome #
Computational studies in enantioselective liquid chromatography: Forty years of evolution in docking- and molecular dynamics-based simulations 111
One-pot, telescoped synthesis of N-aryl-5-aminopyrazoles from anilines in environmentally benign conditions 77
Application of the “inverted chirality columns approach” for the monitoring of asymmetric synthesis protocols 69
Sequence variants in kynurenine aminotransferase II (KAT II) orthologs determine different potencies of the inhibitor S-ESBA 64
Ion pairing to enhance antibiotic drug efficacy. A new approach to fight problematic infections? 61
Targeting the FXR nuclear receptor through a virtual screening approach 59
Tracking Hidden Binding Pockets Along the Molecular Recognition Path of l-Trp to Indoleamine 2,3-Dioxygenase 1 59
Targeting the FXR Nuclear Receptor through a Virtual Screening Approach 58
Asymmetric synthesis of the four diastereoisomers of a novel non-steroidal farnesoid X receptor (FXR) agonist: Role of the chirality on the biological activity 57
Integrated Fragment-Based Approaches on the Route to Novel IDO1 Modulators 57
An Integrated Approach to Ligand- and Structure-Based Drug Design: Development and Application to a Series of Serine Protease Inhibitors 56
N-Decyl-S-trityl-(R)-cysteine, a new chiral selector for "green" ligand-exchange chromatography applications 56
Discovery and characterization of novel potent PARP-1 inhibitors endowed with neuroprotective properties: From TIQ-A to HYDAMTIQ 55
1μs Molecular Dynamics Simulations to study the poisoning effect of the PARP-1 full length enzyme 55
Successful rate gain by combination of multiple techniques 54
a-Amino-b-carboxymuconate-e-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of de Novo Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis 54
Fluorinated Benzyloxyphenyl Piperidine-4-carboxamides with Dual Function against Thrombosis: Inhibitors of Factor Xa and Platelet Aggregation 53
Structural Insights into Monoamine Oxidase Inhibitory Potency and Selectivity of 7-Substituted Coumarins from Ligand- and Target-Based Approaches 53
Binding properties of different categories of IDO1 inhibitors: A microscale thermophoresis study 53
Chromatographic separation of free dafachronic acid epimers with a novel triazole click quinidine-based chiral stationary phase 52
Beyond Bile Acids: Targeting Farnesoid X Receptor (FXR) with Natural and Synthetic Ligands 52
Expanding the horizon of chemotherapeutic targets: From MDM2 to MDMX (MDM4). 51
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy. 51
Binding models of reversible inhibitors to type-B monoamine oxidase 50
Quantum mechanics/molecular mechanics (QM/MM) modeling of the irreversible transamination of L-kynurenine to kynurenic acid: The round dance of kynurenine aminotransferase II 49
Cyclopropyl Dafachronic Acid Stereoisomers as Conformationally Constrained DAF-12 Ligands 49
Mixed-mode chromatography characteristics of chiralpak ZWIX(+) and ZWIX(−) and elucidation of their chromatographic orthogonality for LC × LC application 49
New Insights from Crystallographic Data: Diversity of Structural Motifs and Molecular Recognition Properties between Groups of IDO1 Structures 48
A Natural Prothrombin Mutant Reveals an Unexpected Influence of A-chain Structure on the Activity of Human {alpha}-Thrombin 47
Synthesis and monoamine oxidase inhibitory activity of new pyridazine-, pyrimidine- and 1,2,4-triazine-containing tricyclic derivatives 46
Targeting the conformational transitions of MDM2 and MDMX: insights into dissimilarities and similarities of p53 recognition. 46
Elucidation of the chromatographic enantiomer elution order through computational studies 46
Exploiting Chemical Toolboxes for the Expedited Generation of Tetracyclic Quinolines as a Novel Class of PXR Agonists 46
The Janus-faced nature of IDO1 in infectious diseases: Challenges and therapeutic opportunities 45
4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP) 45
Hydrophilic interaction liquid chromatography of aminoglycoside antibiotics with a diol-type stationary phase 45
N-Aryl-5-aminopyrazole: A Versatile Architecture in Medicinal Chemistry 45
Fragment-based Design of Zwitterionic, Strong Cation- and Weak Anion-Exchange Type Mixed-mode Liquid Chromatography Ligands and their Chromatographic Exploration 44
New potent and selective FXR agonists: design, synthesis and modeling of norcholanylamine derivatives 43
Computational Modeling Overview and Evolution 43
Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors 43
Chiral mobile phase in ligand-exchange chromatography of amino acids: Exploring the copper(II) salt anion effect with a computational approach 42
Optimized one-pot derivatization and enantioseparation of cysteine: Application to the study of a dietary supplement 42
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 42
Binding modes identification through molecular dynamic simulations: a case study with carnosine enantiomers and the Teicoplanin A2-2-based chiral stationary phase 42
Fragment based drug design and diversity-oriented synthesis of carboxylic acid isosteres 42
Recent advances in urea- and thiourea-containing compounds: focus on innovative approaches in medicinal chemistry and organic synthesis 42
Investigation on the Antiplatelet Activity of Pyrrolo[3,2-c]pyridine-Containing Compounds 41
Targeting the conformational transitions of MDM2 and MDMX: Insights into key residues affecting p53 recognition 41
Discovery of 3α,7α,11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid (TC-100), a Novel Bile Acid as Potent and Highly Selective FXR Agonist for Enterohepatic Disorders 41
Improved chromatographic diastereoresolution of cyclopropyl dafachronic acid derivatives using chiral anion exchangers 41
Molecular Doscking and High-Troughput Molecular Dynamics to Detect and Analyze the Binding Site Properties of DAF-12 Orthologs in Parasitic Nematodes 40
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome 40
Design, Synthesis, Crystallographic Studies and Preliminary Biological Appraisal of New Substituted Triazolo[4,3-b]pyridazin-8-amine Derivatives as Tankyrase Inhibitors. 39
Synthesis and biological evaluation of direct thrombin inhibitors bearing 4-(piperidin-1-yl)pyridine at the P1 position with potent anticoagulant activity. 39
Concepts and Molecular Aspects in the Polypharmacology of PARP-1 Inhibitors 39
Enantioselective HPLC analysis to assist the chemical exploration of chiral imidazolines 39
Design, synthesis, molecular modeling and biological activity of chenodeoxycholic acid carbamate derivatives as potent and selective FXR agonists 38
HYDAMTIQ: A New, Potent PARP-1 Inhibitor with Neuroprotective Properties 37
Targeting the Conformational Transitions of MDM2 and MDMX. PART II: Insights into Key Residues Affecting p53 Recognition. 37
Insights in the PARP1 poisoning effect 37
Reshaping antibiotics through hydrophobic drug-bile acid ionic complexation enhances activity against Staphylococcus aureus biofilms 37
Extending SAR of bile acids as FXR ligands: Discovery of 23-N-(carbocinnamyloxy)-3a,7a-dihydroxy-6a-ethyl-24-nor-5b-cholan-23-amine 36
High Affinity Central Benzodiazepine Receptor Ligands. Part 3: Insights into the Pharmacophore and Pattern Recognition Study of Intrinsic Activities of Pyrazolo[4,3-c]quinolin-3-ones 36
Synthesis, physicochemical properties, and biological activity of bile acids 3-glucuronides: Novel insights into bile acid signalling and detoxification 36
Integrating experimental and computational techniques to study chromatographic enantioresolutions of chiral tetrahydroindazole derivatives 36
Navigations of Chemical Space to Further the Understanding of Polypharmacology in Human Nuclear Receptors 35
A rational approach to elucidate human monoamine oxidase molecular selectivity 35
Pyrazole[3,4-e][1,4]thiazepin-7-one Derivatives as a Novel Classo f Farnesoid X Receptor (FXR) Agonists 34
Enantioresolution, stereochemical characterization and biological activity of a chiral large-conductance calcium-activated potassium channel opener. 34
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy 34
ENVIRONMENTALLY FRIENDLY, SEQUENTIAL, ONE-POT SYNTHESIS OF N-ARYL-5-AMINOPYRAZOLES FROM ANILINES 34
Dissecting the allosteric FXR modulation: A chemical biology approach using guggulsterone as a chemical tool 34
Critical Assessment of a Structure-Based Screening Campaign for IDO1 Inhibitors: Tips and Pitfalls 34
The natural mutation by deletion of Lys9 in the thrombin A-chain affects the pKa value of catalytic residues, the overall enzyme’s stability and conformational transitions linked to Na+ binding 33
Natural and Synthetic Geiparvarins are Strong and Selective MAO-B Inhibitors. Synthesis and SAR Studies 33
Targeting the Conformational Transitions of MDM2 and MDMX. PART I: Insights into Dissimilarities and Similarities of p53 Recognition 33
Therapeutic Potential of a Novel Poly(ADP-ribose) Polymerase Inhibitor, Hydamtiq, in Human Pancreatic and Colon Cancers 33
Pyrazole[3,4-e][1,4]thiazepin-7-one derivatives as a novel class of Farnesoid X Receptor (FXR) agonists 33
Molecular Interaction Fields and 3D-QSAR Studies of p53-MDM2 Inhibitors Suggest Additional Features of Ligand-Target Interaction 32
STUDY OF THE MICELLE FORMATION PROCESS OF BILE ACIDS THROUGHMOLECULAR DYAMICS SIMULATIONS 32
Diastereo- and enantioseparation of a Nα-Boc amino acid with a zwitterionic quinine-based stationary phase: Focus on the stereorecognition mechanism 32
Docking Studies and Molecular Dynamic Simulations Reveal Different Features of IDO1 Structure 32
Last ten years (2008–2018) of chiral ligand-exchange chromatography in HPLC: An updated review 32
Microsampling and enantioselective liquid chromatography coupled to mass spectrometry for chiral bioanalysis of novel psychoactive substances 31
Mechanistic investigations on a ligand-exchange system operating with a chiral mobile phase. 31
Design, Synthesis, Crystallographic Studies, and Biological Appraisals of New Tankyrase Inhibitors. 31
The effect of the Cu(II) salt anion in a ligand exchange system operating with a chiral mobile phase 30
Ester derivatives of annulated tetrahydroazocines: a new class of selective acetylcholinesterase inhibitors 30
Exploring the effect of PARP-1 flexibility in docking studies 30
Exploring the enantiorecognition mechanism of Cinchona alkaloid-based zwitterionic chiral stationary phases and the basic trans-paroxetine enantiomers 30
Enantioseparations by high-performance liquid chromatography based on chiral ligand exchange 30
Estimating the hydrophobicity extent of molecular fragments using reversed‐phase liquid chromatography 29
Lipophilicity-related inhibition of blood platelet aggregation by nipecotic acid anilides 29
From polypharmacology to target specificity: the case of PARP inhibitors. 29
New antitubercular drug-bile acid ion pairs as potential active compounds for TB inhalation therapy 29
Discovery of Novel 5-Lipoxygenase-Activating Protein (FLAP) Inhibitors by Exploiting a Multistep Virtual Screening Protocol 29
Deconstructing bile acid signaling pathways 28
The "racemic approach" in the evaluation of the enantiomeric NorA efflux pump inhibition activity of 2-phenylquinoline derivatives 28
Enantioresolution and stereochemical characterization of two chiral sulfoxides endowed with COX-2 inhibitory activity 28
Totale 4.249
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Categoria #
all - tutte 18.925
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 18.925
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201936 0 0 0 0 0 0 0 0 0 0 23 13
2019/2020350 10 4 31 6 47 7 45 9 48 94 28 21
2020/2021639 6 38 10 31 240 36 54 31 84 15 34 60
2021/2022823 15 132 6 21 15 16 22 285 26 57 96 132
2022/20231.714 126 311 26 124 123 187 7 88 624 17 67 14
2023/2024540 55 106 40 12 11 15 156 29 82 33 1 0
Totale 4.748