IRIS - Res&Arch Institutional Research Information System - Research & Archive

CAROTTI, Andrea
 Distribuzione geografica
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Continente #
NA - Nord America 4.209
AS - Asia 3.412
EU - Europa 2.843
SA - Sud America 536
AF - Africa 93
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 3
Totale 11.101
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Nazione #
US - Stati Uniti d'America 4.102
SG - Singapore 1.660
IT - Italia 716
CN - Cina 509
IE - Irlanda 501
HK - Hong Kong 426
RU - Federazione Russa 414
BR - Brasile 412
VN - Vietnam 253
UA - Ucraina 235
DE - Germania 212
FR - Francia 195
FI - Finlandia 142
GB - Regno Unito 110
IN - India 98
BD - Bangladesh 96
KR - Corea 94
SE - Svezia 93
PL - Polonia 60
AR - Argentina 56
CA - Canada 44
TR - Turchia 41
MX - Messico 38
JP - Giappone 35
NL - Olanda 30
UZ - Uzbekistan 28
ZA - Sudafrica 27
ID - Indonesia 22
BE - Belgio 19
CH - Svizzera 19
IQ - Iraq 19
CZ - Repubblica Ceca 18
AT - Austria 17
CO - Colombia 15
EG - Egitto 15
SA - Arabia Saudita 15
EC - Ecuador 14
ES - Italia 14
JO - Giordania 14
PH - Filippine 14
MA - Marocco 11
AE - Emirati Arabi Uniti 10
CL - Cile 10
IL - Israele 10
NP - Nepal 10
PK - Pakistan 10
TN - Tunisia 10
VE - Venezuela 10
GR - Grecia 9
LT - Lituania 9
KZ - Kazakistan 8
MY - Malesia 8
PY - Paraguay 8
DZ - Algeria 7
JM - Giamaica 6
PE - Perù 6
AZ - Azerbaigian 5
CR - Costa Rica 5
AM - Armenia 4
DO - Repubblica Dominicana 4
ET - Etiopia 4
LB - Libano 4
RO - Romania 4
AL - Albania 3
AU - Australia 3
EU - Europa 3
MD - Moldavia 3
OM - Oman 3
BB - Barbados 2
BF - Burkina Faso 2
BG - Bulgaria 2
CI - Costa d'Avorio 2
DK - Danimarca 2
GE - Georgia 2
HU - Ungheria 2
KE - Kenya 2
KG - Kirghizistan 2
LY - Libia 2
ME - Montenegro 2
NO - Norvegia 2
PR - Porto Rico 2
PT - Portogallo 2
RS - Serbia 2
SN - Senegal 2
SV - El Salvador 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
AF - Afghanistan, Repubblica islamica di 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
BO - Bolivia 1
BY - Bielorussia 1
CG - Congo 1
DJ - Gibuti 1
DM - Dominica 1
GH - Ghana 1
GT - Guatemala 1
GY - Guiana 1
IR - Iran 1
Totale 11.080
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Città #
Singapore 1.195
Dublin 501
Chandler 483
San Jose 450
Hong Kong 420
Perugia 289
Ashburn 280
San Mateo 222
Santa Clara 194
Boardman 181
Moscow 142
Beijing 131
Lauterbourg 122
Medford 116
Princeton 115
Altamura 109
Jacksonville 108
Wilmington 97
Munich 91
Seoul 90
Lawrence 88
Ann Arbor 81
Los Angeles 77
New York 71
Ho Chi Minh City 70
Andover 56
Redmond 56
Dong Ket 50
Hanoi 50
The Dalles 46
São Paulo 40
Des Moines 39
Rome 35
Piscataway 32
Helsinki 31
Kraków 31
Chennai 30
Tokyo 29
Saint Petersburg 28
Dallas 27
Warsaw 27
Falls Church 26
Orem 23
Turku 22
Brooklyn 19
Izmir 18
Tashkent 18
Chicago 17
Phoenix 17
San Paolo di Civitate 17
Brussels 16
Montreal 16
Houston 15
Johannesburg 15
Norwalk 15
Shanghai 15
Boston 14
London 14
Mcallen 14
Mexico City 14
Redwood City 14
Woodbridge 14
Atlanta 13
Rio de Janeiro 13
Denver 12
Haiphong 12
Manchester 12
Milan 12
New Delhi 12
Nuremberg 12
Spoleto 12
Amman 11
Cairo 11
Poplar 11
Stockholm 11
Amsterdam 10
Ankara 10
Baghdad 10
Bologna 10
Fremont 10
Hefei 10
Lappeenranta 10
Toronto 10
Brasília 9
Campinas 9
Columbus 9
Frankfurt am Main 9
Guangzhou 9
Guarulhos 9
Macerata 9
Belo Horizonte 8
Curitiba 8
Da Nang 8
Mumbai 8
San Francisco 8
Buffalo 7
Cape Town 7
Medellín 7
Porto Alegre 7
Basingstoke 6
Totale 7.054
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Nome #
Discovery and Structure–Activity Relationships of Novel ssDAF-12 Receptor Modulators 170
Computational studies in enantioselective liquid chromatography: Forty years of evolution in docking- and molecular dynamics-based simulations 161
Application of the “inverted chirality columns approach” for the monitoring of asymmetric synthesis protocols 146
Critical Assessment of a Structure-Based Screening Campaign for IDO1 Inhibitors: Tips and Pitfalls 134
Tracking Hidden Binding Pockets Along the Molecular Recognition Path of l-Trp to Indoleamine 2,3-Dioxygenase 1 132
Integrated Fragment-Based Approaches on the Route to Novel IDO1 Modulators 128
N-Decyl-S-trityl-(R)-cysteine, a new chiral selector for "green" ligand-exchange chromatography applications 128
New Insights from Crystallographic Data: Diversity of Structural Motifs and Molecular Recognition Properties between Groups of IDO1 Structures 123
Chiral mobile phase in ligand-exchange chromatography of amino acids: Exploring the copper(II) salt anion effect with a computational approach 122
Enantioselective HPLC analysis to assist the chemical exploration of chiral imidazolines 122
Asymmetric synthesis of the four diastereoisomers of a novel non-steroidal farnesoid X receptor (FXR) agonist: Role of the chirality on the biological activity 120
a-Amino-b-carboxymuconate-e-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of de Novo Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis 120
Binding properties of different categories of IDO1 inhibitors: A microscale thermophoresis study 119
Optimized one-pot derivatization and enantioseparation of cysteine: Application to the study of a dietary supplement 118
One-pot, telescoped synthesis of N-aryl-5-aminopyrazoles from anilines in environmentally benign conditions 116
1μs Molecular Dynamics Simulations to study the poisoning effect of the PARP-1 full length enzyme 115
Cyclopropyl Dafachronic Acid Stereoisomers as Conformationally Constrained DAF-12 Ligands 114
An Integrated Approach to Ligand- and Structure-Based Drug Design: Development and Application to a Series of Serine Protease Inhibitors 113
Ion pairing to enhance antibiotic drug efficacy. A new approach to fight problematic infections? 112
Targeting the FXR nuclear receptor through a virtual screening approach 109
Fragment-based Design of Zwitterionic, Strong Cation- and Weak Anion-Exchange Type Mixed-mode Liquid Chromatography Ligands and their Chromatographic Exploration 109
Beyond Bile Acids: Targeting Farnesoid X Receptor (FXR) with Natural and Synthetic Ligands 108
Structural Insights into Monoamine Oxidase Inhibitory Potency and Selectivity of 7-Substituted Coumarins from Ligand- and Target-Based Approaches 107
Improved chromatographic diastereoresolution of cyclopropyl dafachronic acid derivatives using chiral anion exchangers 106
Fragment based drug design and diversity-oriented synthesis of carboxylic acid isosteres 106
Binding models of reversible inhibitors to type-B monoamine oxidase 105
Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors 104
Estimating the hydrophobicity extent of molecular fragments using reversed‐phase liquid chromatography 103
Mixed-mode chromatography characteristics of chiralpak ZWIX(+) and ZWIX(−) and elucidation of their chromatographic orthogonality for LC × LC application 103
Elucidation of the chromatographic enantiomer elution order through computational studies 102
Exploiting Chemical Toolboxes for the Expedited Generation of Tetracyclic Quinolines as a Novel Class of PXR Agonists 102
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 102
Binding modes identification through molecular dynamic simulations: a case study with carnosine enantiomers and the Teicoplanin A2-2-based chiral stationary phase 102
Turning a Tumor Microenvironment Pitfall into Opportunity: Discovery of Benzamidoxime as PD-L1 Ligand with pH-Dependent Potency 101
Successful rate gain by combination of multiple techniques 99
Hydrophilic interaction liquid chromatography of aminoglycoside antibiotics with a diol-type stationary phase 99
Sequence variants in kynurenine aminotransferase II (KAT II) orthologs determine different potencies of the inhibitor S-ESBA 99
The Janus-faced nature of IDO1 in infectious diseases: Challenges and therapeutic opportunities 98
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy. 97
Integrating experimental and computational techniques to study chromatographic enantioresolutions of chiral tetrahydroindazole derivatives 97
4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP) 96
Recent advances in urea- and thiourea-containing compounds: focus on innovative approaches in medicinal chemistry and organic synthesis 96
Atypical enantioseparation of a non-ionic form of allantoin with Cinchona alkaloid-based zwitterionic chiral stationary phases 94
Chromatographic separation of free dafachronic acid epimers with a novel triazole click quinidine-based chiral stationary phase 94
Dissecting the allosteric FXR modulation: A chemical biology approach using guggulsterone as a chemical tool 93
Discovery and characterization of novel potent PARP-1 inhibitors endowed with neuroprotective properties: From TIQ-A to HYDAMTIQ 92
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy 92
A Natural Prothrombin Mutant Reveals an Unexpected Influence of A-chain Structure on the Activity of Human {alpha}-Thrombin 90
Discovery of 3α,7α,11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid (TC-100), a Novel Bile Acid as Potent and Highly Selective FXR Agonist for Enterohepatic Disorders 90
Docking Studies and Molecular Dynamic Simulations Reveal Different Features of IDO1 Structure 90
N-Aryl-5-aminopyrazole: A Versatile Architecture in Medicinal Chemistry 90
Synthesis and Characterization of Chiral Iridium Complexes Bearing Carbohydrate Functionalized Pyridincarboxamide Ligands and Their Application as Catalysts in the Asymmetric Transfer Hydrogenation of α-Ketoacids in Water 89
Targeting the conformational transitions of MDM2 and MDMX: insights into dissimilarities and similarities of p53 recognition. 89
Expanding the horizon of chemotherapeutic targets: From MDM2 to MDMX (MDM4). 89
Targeting the Conformational Transitions of MDM2 and MDMX. PART II: Insights into Key Residues Affecting p53 Recognition. 89
Effects of Molecular Dynamics and Replica Exchange Molecular Dynamics in Sampling the Conformational Space of PARP-1 89
Concepts and Molecular Aspects in the Polypharmacology of PARP-1 Inhibitors 88
Last ten years (2008–2018) of chiral ligand-exchange chromatography in HPLC: An updated review 88
A journey in unraveling the enantiorecognition mechanism of 3,5-dinitrobenzoyl-amino acids with two Cinchona alkaloid-based chiral stationary phases: The power of molecular dynamic simulations 87
Targeting the FXR Nuclear Receptor through a Virtual Screening Approach 86
Reshaping antibiotics through hydrophobic drug-bile acid ionic complexation enhances activity against Staphylococcus aureus biofilms 86
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome 86
Microsampling and enantioselective liquid chromatography coupled to mass spectrometry for chiral bioanalysis of novel psychoactive substances 85
Quantum mechanics/molecular mechanics (QM/MM) modeling of the irreversible transamination of L-kynurenine to kynurenic acid: The round dance of kynurenine aminotransferase II 85
Insights in the PARP1 poisoning effect 85
Synthesis, physicochemical properties, and biological activity of bile acids 3-glucuronides: Novel insights into bile acid signalling and detoxification 85
Structural Basis of Human Dimeric α-Amino-β-Carboxymuconate-ε-Semialdehyde Decarboxylase Inhibition With TES-1025 85
Fluorinated Benzyloxyphenyl Piperidine-4-carboxamides with Dual Function against Thrombosis: Inhibitors of Factor Xa and Platelet Aggregation 84
Computational Modeling Overview and Evolution 84
Targeting the Conformational Transitions of MDM2 and MDMX. PART I: Insights into Dissimilarities and Similarities of p53 Recognition 84
Enantioseparation of novel anti-inflammatory chiral sulfoxides with two cellulose dichlorophenylcarbamate-based chiral stationary phases and polar-organic mobile phase(s) 82
Synthesis and monoamine oxidase inhibitory activity of new pyridazine-, pyrimidine- and 1,2,4-triazine-containing tricyclic derivatives 81
New potent and selective FXR agonists: design, synthesis and modeling of norcholanylamine derivatives 80
Design, synthesis, molecular modeling and biological activity of chenodeoxycholic acid carbamate derivatives as potent and selective FXR agonists 80
A rational approach to elucidate human monoamine oxidase molecular selectivity 80
Environmentally Sustainable Achiral and Chiral Chromatographic Analysis of Amino Acids in Food Supplements 79
Targeting the conformational transitions of MDM2 and MDMX: Insights into key residues affecting p53 recognition 78
Efficient enantioresolution of aromatic α-hydroxy acids with Cinchona alkaloid-based zwitterionic stationary phases and volatile polar-ionic eluents 78
Molecular Dynamics-Ensemble Docking and Biophysical Studies for Structure-Based Identification of Non-Amino Acidic Ligands of DDAH-1 77
Synthesis and biological activity of cyclopropyl Δ7-dafachronic acids as DAF-12 receptor ligands 77
Multiple Heart-Cutting Two-Dimensional HPLC-UV Achiral–Chiral Analysis of Branched-Chain Amino Acids in Food Supplements under Environmentally Friendly Conditions 76
Chemical exploration of TGR5 functional hot-spots: Synthesis and structure-activity relationships of C7- and C23-Substituted cholic acid derivatives 76
Synthesis and biological evaluation of direct thrombin inhibitors bearing 4-(piperidin-1-yl)pyridine at the P1 position with potent anticoagulant activity. 76
Elucidation of retention mechanism of dipeptides on a ristocetin A-based chiral stationary phase using a combination of chromatographic and molecular simulation techniques 75
HYDAMTIQ: A New, Potent PARP-1 Inhibitor with Neuroprotective Properties 74
Extending SAR of bile acids as FXR ligands: Discovery of 23-N-(carbocinnamyloxy)-3a,7a-dihydroxy-6a-ethyl-24-nor-5b-cholan-23-amine 74
Therapeutic Potential of a Novel Poly(ADP-ribose) Polymerase Inhibitor, Hydamtiq, in Human Pancreatic and Colon Cancers 74
Pyrazole[3,4-e][1,4]thiazepin-7-one derivatives as a novel class of Farnesoid X Receptor (FXR) agonists 74
Design, Synthesis, Crystallographic Studies and Preliminary Biological Appraisal of New Substituted Triazolo[4,3-b]pyridazin-8-amine Derivatives as Tankyrase Inhibitors. 73
ENVIRONMENTALLY FRIENDLY, SEQUENTIAL, ONE-POT SYNTHESIS OF N-ARYL-5-AMINOPYRAZOLES FROM ANILINES 73
Discovery of Novel 5-Lipoxygenase-Activating Protein (FLAP) Inhibitors by Exploiting a Multistep Virtual Screening Protocol 73
Investigation on the Antiplatelet Activity of Pyrrolo[3,2-c]pyridine-Containing Compounds 72
The "racemic approach" in the evaluation of the enantiomeric NorA efflux pump inhibition activity of 2-phenylquinoline derivatives 72
Exploring the effect of PARP-1 flexibility in docking studies 69
Enantioseparations by high-performance liquid chromatography based on chiral ligand exchange 69
Chiral high-performance liquid chromatography analysis of mono-, di-, and triacylglycerols with amylose- and cellulose-phenylcarbamate-based stationary phases 68
Chromatographic enantioresolution and stereochemical characterization of synthetic cannabinoid receptor agonists with Whelk-O®1 chiral stationary phases under mass spectrometry compatible reversed-phase conditions: A study case with seized samples 67
STUDY OF THE MICELLE FORMATION PROCESS OF BILE ACIDS THROUGHMOLECULAR DYAMICS SIMULATIONS 67
Deconstructing bile acid signaling pathways 67
Diastereo- and enantioseparation of a Nα-Boc amino acid with a zwitterionic quinine-based stationary phase: Focus on the stereorecognition mechanism 67
Totale 9.459
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Categoria #
all - tutte 52.560
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 52.560
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202160 0 0 0 0 0 0 0 0 0 0 0 60
2021/2022823 15 132 6 21 15 16 22 285 26 57 96 132
2022/20231.714 126 311 26 124 123 187 7 88 624 17 67 14
2023/2024803 55 106 40 12 11 15 156 29 82 33 120 144
2024/20252.080 39 193 122 79 246 144 146 96 413 133 320 149
2025/20264.520 298 343 236 536 617 400 791 253 435 366 162 83
Totale 11.611