IRIS - Res&Arch Institutional Research Information System - Research & Archive

CAROTTI, Andrea
 Distribuzione geografica
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Continente #
NA - Nord America 2.475
EU - Europa 1.767
AS - Asia 666
AF - Africa 10
SA - Sud America 4
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 1
Totale 4.926
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Nazione #
US - Stati Uniti d'America 2.463
IE - Irlanda 500
IT - Italia 478
SG - Singapore 235
UA - Ucraina 219
HK - Hong Kong 193
CN - Cina 119
FI - Finlandia 104
DE - Germania 99
RU - Federazione Russa 81
SE - Svezia 81
FR - Francia 57
VN - Vietnam 52
GB - Regno Unito 35
PL - Polonia 31
KR - Corea 22
BE - Belgio 17
TR - Turchia 17
CH - Svizzera 15
CZ - Repubblica Ceca 15
NL - Olanda 10
GR - Grecia 9
AT - Austria 8
EG - Egitto 8
MX - Messico 8
UZ - Uzbekistan 8
IL - Israele 7
JP - Giappone 7
CA - Canada 4
ES - Italia 3
EU - Europa 3
BG - Bulgaria 2
BR - Brasile 2
CI - Costa d'Avorio 2
CL - Cile 2
PH - Filippine 2
AE - Emirati Arabi Uniti 1
AZ - Azerbaigian 1
HU - Ungheria 1
IN - India 1
LB - Libano 1
MD - Moldavia 1
NZ - Nuova Zelanda 1
PT - Portogallo 1
Totale 4.926
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Città #
Dublin 500
Chandler 483
San Mateo 222
Hong Kong 192
Boardman 181
Perugia 180
Singapore 169
Medford 116
Princeton 115
Altamura 109
Jacksonville 107
Wilmington 97
Lawrence 88
Ann Arbor 81
Andover 56
Redmond 56
Dong Ket 50
Beijing 48
Des Moines 36
Kraków 31
Saint Petersburg 28
Falls Church 26
Ashburn 23
Santa Clara 21
Helsinki 20
Los Angeles 19
Seoul 19
San Paolo di Civitate 17
Izmir 16
Brussels 15
Norwalk 15
Mcallen 14
New York 14
Redwood City 14
Rome 14
Woodbridge 14
Spoleto 12
Milan 11
Dallas 10
Fremont 10
Bologna 9
Cairo 8
Moscow 8
Brno 6
Munich 6
Ness Ziona 6
Renton 6
Simi Valley 6
Tübingen 6
Frankfurt Am Main 5
Lappeenranta 5
Shanghai 5
Tokyo 5
Bracciano 4
Chicago 4
Florence 4
Houston 4
Hradec Králové 4
Lausanne 4
Macerata 4
Montefalco 4
Olomouc 4
San Giustino 4
Ternopil 4
Toronto 4
Washington 4
Winston-Salem 4
Cassino 3
Detroit 3
Groningen 3
Nagold 3
Palermo 3
Siena 3
Terni 3
Wear 3
Abidjan 2
Amsterdam 2
Auburn Hills 2
Bellagio 2
Calcinaia 2
Da Nang 2
Den Haag 2
Esslingen am Neckar 2
Fairfield 2
Falkenstein 2
Foligno 2
Fuzhou 2
Guangzhou 2
Hanover 2
Irapuato 2
Jesi 2
Livorno 2
Madrid 2
Nea Smyrni 2
Prato 2
Prineville 2
Quezon City 2
Shenzhen 2
The Hague 2
Vienna 2
Totale 3.460
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Nome #
Computational studies in enantioselective liquid chromatography: Forty years of evolution in docking- and molecular dynamics-based simulations 117
One-pot, telescoped synthesis of N-aryl-5-aminopyrazoles from anilines in environmentally benign conditions 80
Application of the “inverted chirality columns approach” for the monitoring of asymmetric synthesis protocols 74
Ion pairing to enhance antibiotic drug efficacy. A new approach to fight problematic infections? 69
Tracking Hidden Binding Pockets Along the Molecular Recognition Path of l-Trp to Indoleamine 2,3-Dioxygenase 1 69
Sequence variants in kynurenine aminotransferase II (KAT II) orthologs determine different potencies of the inhibitor S-ESBA 66
Integrated Fragment-Based Approaches on the Route to Novel IDO1 Modulators 65
Asymmetric synthesis of the four diastereoisomers of a novel non-steroidal farnesoid X receptor (FXR) agonist: Role of the chirality on the biological activity 64
Binding properties of different categories of IDO1 inhibitors: A microscale thermophoresis study 63
Targeting the FXR nuclear receptor through a virtual screening approach 62
1μs Molecular Dynamics Simulations to study the poisoning effect of the PARP-1 full length enzyme 62
N-Decyl-S-trityl-(R)-cysteine, a new chiral selector for "green" ligand-exchange chromatography applications 62
Targeting the FXR Nuclear Receptor through a Virtual Screening Approach 61
a-Amino-b-carboxymuconate-e-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of de Novo Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis 61
An Integrated Approach to Ligand- and Structure-Based Drug Design: Development and Application to a Series of Serine Protease Inhibitors 60
Chromatographic separation of free dafachronic acid epimers with a novel triazole click quinidine-based chiral stationary phase 59
Discovery and characterization of novel potent PARP-1 inhibitors endowed with neuroprotective properties: From TIQ-A to HYDAMTIQ 58
Successful rate gain by combination of multiple techniques 58
Fluorinated Benzyloxyphenyl Piperidine-4-carboxamides with Dual Function against Thrombosis: Inhibitors of Factor Xa and Platelet Aggregation 57
Cyclopropyl Dafachronic Acid Stereoisomers as Conformationally Constrained DAF-12 Ligands 57
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy. 56
New Insights from Crystallographic Data: Diversity of Structural Motifs and Molecular Recognition Properties between Groups of IDO1 Structures 56
Expanding the horizon of chemotherapeutic targets: From MDM2 to MDMX (MDM4). 55
Structural Insights into Monoamine Oxidase Inhibitory Potency and Selectivity of 7-Substituted Coumarins from Ligand- and Target-Based Approaches 55
Elucidation of the chromatographic enantiomer elution order through computational studies 55
Binding models of reversible inhibitors to type-B monoamine oxidase 54
Discovery of 3α,7α,11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid (TC-100), a Novel Bile Acid as Potent and Highly Selective FXR Agonist for Enterohepatic Disorders 54
Beyond Bile Acids: Targeting Farnesoid X Receptor (FXR) with Natural and Synthetic Ligands 54
Mixed-mode chromatography characteristics of chiralpak ZWIX(+) and ZWIX(−) and elucidation of their chromatographic orthogonality for LC × LC application 54
The Janus-faced nature of IDO1 in infectious diseases: Challenges and therapeutic opportunities 53
Quantum mechanics/molecular mechanics (QM/MM) modeling of the irreversible transamination of L-kynurenine to kynurenic acid: The round dance of kynurenine aminotransferase II 52
Exploiting Chemical Toolboxes for the Expedited Generation of Tetracyclic Quinolines as a Novel Class of PXR Agonists 51
N-Aryl-5-aminopyrazole: A Versatile Architecture in Medicinal Chemistry 51
A Natural Prothrombin Mutant Reveals an Unexpected Influence of A-chain Structure on the Activity of Human {alpha}-Thrombin 50
Synthesis and monoamine oxidase inhibitory activity of new pyridazine-, pyrimidine- and 1,2,4-triazine-containing tricyclic derivatives 50
Targeting the conformational transitions of MDM2 and MDMX: insights into dissimilarities and similarities of p53 recognition. 50
Hydrophilic interaction liquid chromatography of aminoglycoside antibiotics with a diol-type stationary phase 50
Targeting the conformational transitions of MDM2 and MDMX: Insights into key residues affecting p53 recognition 49
4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP) 49
Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors 49
Improved chromatographic diastereoresolution of cyclopropyl dafachronic acid derivatives using chiral anion exchangers 49
Computational Modeling Overview and Evolution 47
Optimized one-pot derivatization and enantioseparation of cysteine: Application to the study of a dietary supplement 47
Fragment-based Design of Zwitterionic, Strong Cation- and Weak Anion-Exchange Type Mixed-mode Liquid Chromatography Ligands and their Chromatographic Exploration 47
Recent advances in urea- and thiourea-containing compounds: focus on innovative approaches in medicinal chemistry and organic synthesis 47
New potent and selective FXR agonists: design, synthesis and modeling of norcholanylamine derivatives 46
Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers 46
Binding modes identification through molecular dynamic simulations: a case study with carnosine enantiomers and the Teicoplanin A2-2-based chiral stationary phase 46
Fragment based drug design and diversity-oriented synthesis of carboxylic acid isosteres 46
Investigation on the Antiplatelet Activity of Pyrrolo[3,2-c]pyridine-Containing Compounds 45
Chiral mobile phase in ligand-exchange chromatography of amino acids: Exploring the copper(II) salt anion effect with a computational approach 45
Concepts and Molecular Aspects in the Polypharmacology of PARP-1 Inhibitors 45
Design, synthesis, molecular modeling and biological activity of chenodeoxycholic acid carbamate derivatives as potent and selective FXR agonists 44
Pyrazole[3,4-e][1,4]thiazepin-7-one derivatives as a novel class of Farnesoid X Receptor (FXR) agonists 44
Critical Assessment of a Structure-Based Screening Campaign for IDO1 Inhibitors: Tips and Pitfalls 44
Molecular Doscking and High-Troughput Molecular Dynamics to Detect and Analyze the Binding Site Properties of DAF-12 Orthologs in Parasitic Nematodes 43
Synthesis and biological evaluation of direct thrombin inhibitors bearing 4-(piperidin-1-yl)pyridine at the P1 position with potent anticoagulant activity. 43
Targeting the Conformational Transitions of MDM2 and MDMX. PART II: Insights into Key Residues Affecting p53 Recognition. 43
Insights in the PARP1 poisoning effect 42
Synthesis, physicochemical properties, and biological activity of bile acids 3-glucuronides: Novel insights into bile acid signalling and detoxification 42
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome 42
Design, Synthesis, Crystallographic Studies and Preliminary Biological Appraisal of New Substituted Triazolo[4,3-b]pyridazin-8-amine Derivatives as Tankyrase Inhibitors. 41
Reshaping antibiotics through hydrophobic drug-bile acid ionic complexation enhances activity against Staphylococcus aureus biofilms 41
Enantioselective HPLC analysis to assist the chemical exploration of chiral imidazolines 41
HYDAMTIQ: A New, Potent PARP-1 Inhibitor with Neuroprotective Properties 40
Extending SAR of bile acids as FXR ligands: Discovery of 23-N-(carbocinnamyloxy)-3a,7a-dihydroxy-6a-ethyl-24-nor-5b-cholan-23-amine 40
Targeting the Conformational Transitions of MDM2 and MDMX. PART I: Insights into Dissimilarities and Similarities of p53 Recognition 40
Docking Studies and Molecular Dynamic Simulations Reveal Different Features of IDO1 Structure 40
Dissecting the allosteric FXR modulation: A chemical biology approach using guggulsterone as a chemical tool 40
Integrating experimental and computational techniques to study chromatographic enantioresolutions of chiral tetrahydroindazole derivatives 40
Pyrazole[3,4-e][1,4]thiazepin-7-one Derivatives as a Novel Classo f Farnesoid X Receptor (FXR) Agonists 39
Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy 39
ENVIRONMENTALLY FRIENDLY, SEQUENTIAL, ONE-POT SYNTHESIS OF N-ARYL-5-AMINOPYRAZOLES FROM ANILINES 39
A rational approach to elucidate human monoamine oxidase molecular selectivity 39
Therapeutic Potential of a Novel Poly(ADP-ribose) Polymerase Inhibitor, Hydamtiq, in Human Pancreatic and Colon Cancers 39
High Affinity Central Benzodiazepine Receptor Ligands. Part 3: Insights into the Pharmacophore and Pattern Recognition Study of Intrinsic Activities of Pyrazolo[4,3-c]quinolin-3-ones 38
Navigations of Chemical Space to Further the Understanding of Polypharmacology in Human Nuclear Receptors 38
Estimating the hydrophobicity extent of molecular fragments using reversed‐phase liquid chromatography 37
The natural mutation by deletion of Lys9 in the thrombin A-chain affects the pKa value of catalytic residues, the overall enzyme’s stability and conformational transitions linked to Na+ binding 37
Enantioresolution, stereochemical characterization and biological activity of a chiral large-conductance calcium-activated potassium channel opener. 37
Last ten years (2008–2018) of chiral ligand-exchange chromatography in HPLC: An updated review 37
Enantioseparation of novel anti-inflammatory chiral sulfoxides with two cellulose dichlorophenylcarbamate-based chiral stationary phases and polar-organic mobile phase(s) 37
Microsampling and enantioselective liquid chromatography coupled to mass spectrometry for chiral bioanalysis of novel psychoactive substances 36
Natural and Synthetic Geiparvarins are Strong and Selective MAO-B Inhibitors. Synthesis and SAR Studies 36
Molecular Interaction Fields and 3D-QSAR Studies of p53-MDM2 Inhibitors Suggest Additional Features of Ligand-Target Interaction 35
STUDY OF THE MICELLE FORMATION PROCESS OF BILE ACIDS THROUGHMOLECULAR DYAMICS SIMULATIONS 35
Diastereo- and enantioseparation of a Nα-Boc amino acid with a zwitterionic quinine-based stationary phase: Focus on the stereorecognition mechanism 35
Synthesis and Characterization of Chiral Iridium Complexes Bearing Carbohydrate Functionalized Pyridincarboxamide Ligands and Their Application as Catalysts in the Asymmetric Transfer Hydrogenation of α-Ketoacids in Water 34
Efficient enantioresolution of aromatic α-hydroxy acids with Cinchona alkaloid-based zwitterionic stationary phases and volatile polar-ionic eluents 34
The effect of the Cu(II) salt anion in a ligand exchange system operating with a chiral mobile phase 33
Ester derivatives of annulated tetrahydroazocines: a new class of selective acetylcholinesterase inhibitors 33
Exploring the effect of PARP-1 flexibility in docking studies 33
Mechanistic investigations on a ligand-exchange system operating with a chiral mobile phase. 33
Design, Synthesis, Crystallographic Studies, and Biological Appraisals of New Tankyrase Inhibitors. 33
Exploring the enantiorecognition mechanism of Cinchona alkaloid-based zwitterionic chiral stationary phases and the basic trans-paroxetine enantiomers 33
Lipophilicity-related inhibition of blood platelet aggregation by nipecotic acid anilides 32
From polypharmacology to target specificity: the case of PARP inhibitors. 32
The "racemic approach" in the evaluation of the enantiomeric NorA efflux pump inhibition activity of 2-phenylquinoline derivatives 32
Enantioseparations by high-performance liquid chromatography based on chiral ligand exchange 32
New antitubercular drug-bile acid ion pairs as potential active compounds for TB inhalation therapy 31
Totale 4.735
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Categoria #
all - tutte 24.819
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.819
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020305 0 0 0 6 47 7 45 9 48 94 28 21
2020/2021639 6 38 10 31 240 36 54 31 84 15 34 60
2021/2022823 15 132 6 21 15 16 22 285 26 57 96 132
2022/20231.714 126 311 26 124 123 187 7 88 624 17 67 14
2023/2024803 55 106 40 12 11 15 156 29 82 33 120 144
2024/2025355 39 193 122 1 0 0 0 0 0 0 0 0
Totale 5.366