IRIS - Res&Arch Institutional Research Information System - Research & Archive

GROHMANN, Ursula
 Distribuzione geografica
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Continente #
NA - Nord America 7.182
EU - Europa 5.498
AS - Asia 5.066
SA - Sud America 868
AF - Africa 128
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 7
Totale 18.759
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Nazione #
US - Stati Uniti d'America 7.019
SG - Singapore 2.442
IT - Italia 1.118
IE - Irlanda 793
CN - Cina 747
BR - Brasile 676
UA - Ucraina 673
HK - Hong Kong 607
RU - Federazione Russa 556
VN - Vietnam 547
SE - Svezia 515
DE - Germania 423
FR - Francia 366
RO - Romania 278
FI - Finlandia 252
GB - Regno Unito 158
IN - India 142
KR - Corea 109
CA - Canada 80
BD - Bangladesh 73
AR - Argentina 67
TR - Turchia 66
CZ - Repubblica Ceca 57
MX - Messico 50
BE - Belgio 49
IQ - Iraq 47
AT - Austria 44
PL - Polonia 43
NL - Olanda 41
JP - Giappone 40
PK - Pakistan 39
CO - Colombia 38
ZA - Sudafrica 35
CH - Svizzera 34
ID - Indonesia 33
EC - Ecuador 29
UZ - Uzbekistan 28
ES - Italia 27
GR - Grecia 22
VE - Venezuela 20
CI - Costa d'Avorio 19
PH - Filippine 17
SA - Arabia Saudita 17
LB - Libano 14
MA - Marocco 14
JO - Giordania 10
MY - Malesia 10
PE - Perù 10
PY - Paraguay 10
AZ - Azerbaigian 9
EU - Europa 9
KE - Kenya 9
LT - Lituania 9
TN - Tunisia 9
AE - Emirati Arabi Uniti 8
CL - Cile 8
ET - Etiopia 8
EG - Egitto 7
IL - Israele 7
PS - Palestinian Territory 7
JM - Giamaica 6
TH - Thailandia 6
DZ - Algeria 5
GE - Georgia 5
OM - Oman 5
UY - Uruguay 5
AU - Australia 4
BG - Bulgaria 4
BO - Bolivia 4
HU - Ungheria 4
IR - Iran 4
KZ - Kazakistan 4
MD - Moldavia 4
NG - Nigeria 4
NI - Nicaragua 4
PA - Panama 4
PT - Portogallo 4
SN - Senegal 4
AL - Albania 3
CR - Costa Rica 3
DK - Danimarca 3
HN - Honduras 3
HR - Croazia 3
KW - Kuwait 3
MN - Mongolia 3
NP - Nepal 3
RS - Serbia 3
AM - Armenia 2
AO - Angola 2
EE - Estonia 2
GA - Gabon 2
GT - Guatemala 2
KG - Kirghizistan 2
LC - Santa Lucia 2
LV - Lettonia 2
NZ - Nuova Zelanda 2
QA - Qatar 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
A2 - ???statistics.table.value.countryCode.A2??? 1
Totale 18.726
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Città #
Singapore 1.838
Chandler 861
Dublin 793
Hong Kong 602
Perugia 598
San Jose 538
San Mateo 440
Ashburn 371
Jacksonville 341
Boardman 301
Bucharest 272
Santa Clara 250
Dong Ket 226
Altamura 204
Wilmington 196
Medford 192
Moscow 191
Beijing 189
Princeton 188
Munich 157
Lauterbourg 156
Lawrence 153
Redmond 139
Ann Arbor 136
Des Moines 130
Andover 121
Los Angeles 118
Seoul 101
Ho Chi Minh City 100
Falls Church 92
New York 90
The Dalles 78
Hanoi 68
São Paulo 67
Turku 55
Orem 52
Saint Petersburg 51
Brussels 49
Dearborn 49
Helsinki 47
Norwalk 43
Woodbridge 43
Dallas 42
Council Bluffs 40
Piscataway 40
Chicago 39
Chennai 36
San Paolo di Civitate 35
Tokyo 33
Brno 32
Houston 32
Warsaw 31
Brooklyn 30
Frankfurt am Main 28
Montreal 28
Nuremberg 28
Pisa 26
Johannesburg 25
Izmir 24
Redwood City 23
Shanghai 23
Boston 22
Fremont 22
London 22
Atlanta 21
Olomouc 21
Phoenix 21
Rome 21
Columbus 20
Rio de Janeiro 20
Abidjan 19
Denver 19
Vienna 19
Baghdad 18
Haiphong 18
Manchester 17
Mumbai 17
Stockholm 17
Milan 16
Toronto 16
Da Nang 15
Poplar 15
Tashkent 15
Amsterdam 14
Mexico City 14
Nanjing 14
San Francisco 14
Lahore 13
Seattle 13
Ankara 12
Auburn Hills 12
Falkenstein 12
Guangzhou 12
Hefei 12
Belo Horizonte 11
Biên Hòa 11
Bogotá 11
Den Haag 11
Medellín 11
Ottawa 11
Totale 11.900
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Nome #
Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3-dioxygenase1 227
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1 211
Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells 204
A GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune Suppression. 203
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells 200
Amino-acid sensing and degrading pathways in immune regulation 196
Aryl hydrocarbon receptor control of a disease tolerance defence pathway. 190
Distinct roles of immunoreceptor tyrosine-based motifs in immunosuppressive indoleamine 2,3-dioxygenase 1. 183
Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells 182
Advances in indoleamine 2,3-dioxygenase 1 medicinal chemistry 179
Amino acid metabolism as drug target in autoimmune diseases 179
Identification of a 2-propanol analogue modulating the non-enzymatic function of indoleamine 2,3-dioxygenase 1 175
Accelerated hematopoietic recovery and protective effect of the cyclooxygenase inhibitor indomethacin in bacterial infection of neutropenic mice. 162
IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII 161
87P - Towards the identification of the mechanism of action of antitumor 1-methyl-D-tryptophan 158
Fragment-based approach to identify IDO1 inhibitor building blocks 155
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation 155
IL‐35Ig–expressing dendritic cells induce tolerance via Arginase 1 153
88P - Relationship between functions and intracellular localization of the immune checkpoint target indoleamine 2, 3-dioxygenase 1 151
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy 148
A retroviral peptide encoded by mutated env p15E gene is recognized by specific CD8+ T lymphocytes on drug-treated murine mastocytoma P815. 147
CD8+ cell activation to a major mastocytoma rejection antigen, P815AB: requirement for tum- or helper peptides in priming for skin test reactivity to a P815AB-related peptide 144
Dendritic cells expressing ectopic IL-35Ig induce IDO-related tolerance in vivo. 144
Is It Time to Use Probiotics to Prevent or Treat Obesity? 144
A novel mutation of indoleamine 2,3-dioxygenase 1 causes a rapid proteasomal degradation and compromises protein function 144
LPS-conditioned dendritic cells confer endotoxin tolerance contingent on tryptophan catabolism 143
3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine 142
Cutting edge: Autocrine TGF-beta sustains default tolerogenesis by IDO-competent dendritic cells. 141
T cell apoptosis by kynurenines. 137
Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1 in juvenile diabetes 136
The TGF-β/IDO axis in infectious tolerance. 135
Critical Assessment of a Structure-Based Screening Campaign for IDO1 Inhibitors: Tips and Pitfalls 134
Tracking Hidden Binding Pockets Along the Molecular Recognition Path of l-Trp to Indoleamine 2,3-Dioxygenase 1 132
Immunogenic tumor variants induced by drug treatment of the L5178Y lymphoma: search for serologically defined antigens at the clonal level. 130
Immunoregulatory interplay between arginine and tryptophan metabolism in health and disease 130
Cell-mediated immunity to chemically xenogenized tumors--IV. Production of lymphokine activity by, and in response to, highly immunogenic cells. 129
Aryl hydrocarbon Receptor and RelB control long term expression of Indoleamine 2,3-dioxygenase-1 in endotoxin tolerance 129
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86. 128
Increase of natural killer activity of mouse lymphocytes following in vitro and in vivo treatment with lithium. 128
A novel metabotropic glutamate receptor 4 allosteric modulator effective in multiple sclerosis experimental autoimmune encephalomyelitis (EAE) mouse model 128
A TLR9/TRIF pathway induces tolerance via TGF-beta and tryptophan catabolism in plasmacytoid dendritic cells 127
Antigen-specific immunoregulation by IL-35Ig-transfected dendritic cells 127
Forced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes 124
New Insights from Crystallographic Data: Diversity of Structural Motifs and Molecular Recognition Properties between Groups of IDO1 Structures 123
Dual effect of IL-4 on resistance to systemic gram-negative infection and production on TNF-alfa 122
Circulating levels of IL-10 are critically related to growth and rejection patterns of murine mastocytoma cells. 122
Xenograft of microencapsulated sertoli cells reverses T1DM in NOD mice by inducing neogenesis of beta-cells. 121
Preclinical discovery and development of fingolimod for the treatment of multiple sclerosis 121
Ectopic expression of IL-35Ig by dendritic cells induces tolerance via Arginase 1. 120
Novel mutations in the WFS1 gene are associated with Wolfram syndrome and systemic inflammation 120
Neutralization of IL-10 up-regulates nitric oxide production and protects susceptible mice from challenge with Candida albicans. 119
CD40 ligation prevents onset of tolerogenic properties in human dendritic cells treated with CTLA-4-Ig. 119
T-cell subsets, IFN-gamma production and efferent specificity in anti-parental tumor immunity induced by mouse sensitization with xenogenized variant cells. 118
Different partners, opposite outcomes: A New Perspective of the Immunobiology of Indoleamine 2,3-Dioxygenase 118
Amino acid metabolism in rheumatoid arthritis: Friend or foe? 117
CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice 116
Tryptophan catabolism in IDO+ plasmacytoid dendritic cells 116
Evidence for tumor necrosis factor alpha as a mediator of the toxicity of a cyclooxygenase inhibitor in Gram-negative sepsis. 116
Islet antigen-pulsed dendritic cells expressing ectopic IL-35Ig protect nonobese diabetic mice from autoimmune diabetes. 116
Effects of probiotic administration on immune responses of children and adolescents with type 1 diabetes to a quadrivalent inactivated influenza vaccine 115
The immunosuppressive activity of proinflammatory cytokines in experimental models: potential for therapeutic intervention in autoimmunity. 114
Microscale thermophoresis and docking studies suggest lapachol and auraptene are ligands of IDO1 114
Autocrine IL-12 is involved in dendritic cell modulation via CD40 ligation 113
IL-12 acts selectively on CD8a- dendritic cells to enhance presentation of a tumor peptide in vivo 112
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells 110
Cell-mediated immunity to chemically xenogenized tumors. I. Inhibition by specific antisera and H-2 association of the novel antigens. 109
CD40 ligand and CTLA-4 are reciprocally regulated in the Th1 cell proliferative response sustained by CD8+ dendritic cells. 108
A tumor-associated and self antigen peptide presented by dendritic cells may induce T cell anergy in vivo, but IL-12 can prevent or revert the anergic state 106
Interleukin-6 (IL-6) prevents activation-induced cell death (AICD): Interleukin-2-independent inhibition of Fas/FasL expression and cell death 105
O6-alkylguanine-DNA alkyltransferase attenuates triazene-induced cytotoxicity and tumor cell immunogenicity in murine L1210 leukemia 105
Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma 104
Dendritic cells, interleukin 12, and CD4+ lymphocytes in the initiation of class I-restricted reactivity to a tumor/self peptide. 102
Ligand Binding and Functional Selectivity ofl-Tryptophan Metabolites at the Mouse Aryl Hydrocarbon Receptor (mAhR) 102
Modulation of tryptophan catabolism by regulatory T cells 101
Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymes. 100
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease 100
Pathogenetic Interplay Between IL-6 and Tryptophan Metabolism in an Experimental Model of Obesity 100
CD40 ligation ablates the tolerogenic potential of lymphoid dendritic cells 99
Course of primary candidiasis in T cell-depleted mice infected with attenuated variant cells. 98
A general partnership between AhR and tryptophan catabolic enzymes and its role in endotoxin tolerance 98
Reinstalling immune regulatory tryptophan catabolism in juvenile diabetes via interleukin 6 receptor blockade 98
IL-6 inhibits the tolerogenic function of CD8 alpha+ dendritic cells expressing indoleamine 2,3-dioxygenase. 97
Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12 97
Cutting edge: silencing suppressor of cytokine signaling 3 expression in dendritic cells turns CD28-Ig from immune adjuvant to suppressant. 97
High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway. 97
Multiple point mutations in an endogenous retroviral gene confer high immunogenicity on a drug-treated murine 96
T cell apoptosis by tryptophan catabolism 96
Towards the identification of a tolerogenic signature in IDO-competent dendritic cells 96
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice 96
Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells. 95
Indoleamine 2,3-dioxygenase, transcriptional regulation and autoimmunity. 94
CTLA-4-immunoglobulin and indoleamine 2,3 dioxygenase in dominant tolerance. 94
Bioengineering heterodimeric cytokines: turning promiscuous proteins into therapeutic agents. 94
Loss of IDO1 Expression From Human Pancreatic -Cells Precedes Their Destruction During the Development of Type 1 Diabetes 94
Induction of immunosuppressive functions and NF-kappa B by FLIP in monocytes 94
CTLA-4-Ig regulates tryptophan catabolism in vivo. 93
Gamma interferon modifies CD4+ subset expression in murine candidiasis. 93
Cell-mediated immunity to chemically xenogenized tumors--III. Generation of monoclonal antibodies interfering with reactivity to novel antigens. 93
Ectopic expression of IL-35Ig by dendritic cells induces IDO-related tolerance in vivo 92
The landscape of AhR regulators and coregulators to fine-tune AhR functions 92
Totale 12.692
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Categoria #
all - tutte 80.566
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 80.566
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021253 0 0 0 0 0 0 0 0 0 0 0 253
2021/20222.205 34 315 32 100 100 58 29 521 151 216 199 450
2022/20233.021 207 559 39 228 278 351 3 144 1.047 10 108 47
2023/20241.175 85 147 37 23 8 10 296 31 104 26 166 242
2024/20252.687 37 225 141 151 327 144 113 190 508 157 422 272
2025/20266.403 394 438 378 859 823 618 1.117 396 663 524 137 56
Totale 19.326