IRIS - Res&Arch Institutional Research Information System - Research & Archive

GROHMANN, Ursula
 Distribuzione geografica
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Continente #
NA - Nord America 4.972
EU - Europa 4.114
AS - Asia 1.441
AF - Africa 18
Continente sconosciuto - Info sul continente non disponibili 10
SA - Sud America 3
OC - Oceania 1
Totale 10.559
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Nazione #
US - Stati Uniti d'America 4.954
IT - Italia 925
IE - Irlanda 791
UA - Ucraina 662
SG - Singapore 526
SE - Svezia 498
HK - Hong Kong 363
RO - Romania 273
CN - Cina 245
VN - Vietnam 226
DE - Germania 219
FI - Finlandia 171
FR - Francia 171
RU - Federazione Russa 135
GB - Regno Unito 67
CZ - Repubblica Ceca 50
BE - Belgio 48
CH - Svizzera 28
AT - Austria 24
TR - Turchia 22
GR - Grecia 21
KR - Corea 19
CI - Costa d'Avorio 16
CA - Canada 15
NL - Olanda 15
UZ - Uzbekistan 12
LB - Libano 10
EU - Europa 9
IN - India 8
PL - Polonia 7
JP - Giappone 6
BR - Brasile 3
MX - Messico 3
PT - Portogallo 3
SA - Arabia Saudita 2
A2 - ???statistics.table.value.countryCode.A2??? 1
DK - Danimarca 1
HR - Croazia 1
HU - Ungheria 1
LK - Sri Lanka 1
LT - Lituania 1
LV - Lettonia 1
MA - Marocco 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
QA - Qatar 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 10.559
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Città #
Chandler 861
Dublin 791
Perugia 508
San Mateo 440
Singapore 429
Hong Kong 362
Jacksonville 340
Boardman 299
Bucharest 272
Dong Ket 226
Santa Clara 215
Altamura 204
Wilmington 196
Medford 192
Princeton 188
Lawrence 153
Redmond 139
Ann Arbor 136
Des Moines 129
Andover 121
Beijing 108
Falls Church 92
Saint Petersburg 51
Ashburn 50
Dearborn 49
Brussels 48
Norwalk 43
Woodbridge 42
San Paolo di Civitate 35
Brno 32
Munich 27
Pisa 26
Helsinki 25
Redwood City 23
Fremont 21
Izmir 21
Los Angeles 21
New York 21
Dallas 18
Abidjan 16
Houston 15
Olomouc 15
Auburn Hills 12
Chicago 12
Seoul 12
Vienna 12
Den Haag 11
Moscow 11
Nanjing 9
San Diego 9
Shanghai 9
Ottawa 8
Cambridge 7
Hefei 7
Hanover 6
Saint Louis 6
Terni 6
Frankfurt Am Main 5
Guangzhou 5
Spoleto 5
Chengdu 4
Falkenstein 4
Jinan 4
Livorno 4
Nagpur 4
Nanchang 4
Nürnberg 4
Rome 4
Shenyang 4
Tappahannock 4
Winnipeg 4
Cassino 3
Civitanova Marche 3
Esslingen am Neckar 3
Ludwigshafen 3
Nichelino 3
Paris 3
Simi Valley 3
Tacoma 3
Wuhan 3
Amsterdam 2
Assisi 2
Baotou 2
Bologna 2
Boston 2
Catania 2
Changsha 2
Collazzone 2
Edinburgh 2
Florence 2
Jeddah 2
Kunming 2
Lausanne 2
L’Aquila 2
Macerata 2
Milan 2
Monmouth Junction 2
Nagold 2
Nea Smyrni 2
Ningbo 2
Totale 7.263
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Nome #
Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3-dioxygenase1 174
Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells 138
Distinct roles of immunoreceptor tyrosine-based motifs in immunosuppressive indoleamine 2,3-dioxygenase 1. 130
A GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune Suppression. 127
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1 127
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells 124
Aryl hydrocarbon receptor control of a disease tolerance defence pathway. 122
Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells 118
Amino-acid sensing and degrading pathways in immune regulation 116
Identification of a 2-propanol analogue modulating the non-enzymatic function of indoleamine 2,3-dioxygenase 1 109
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy 107
IL‐35Ig–expressing dendritic cells induce tolerance via Arginase 1 105
Amino acid metabolism as drug target in autoimmune diseases 104
T cell apoptosis by kynurenines. 103
Advances in indoleamine 2,3-dioxygenase 1 medicinal chemistry 101
IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII 95
Fragment-based approach to identify IDO1 inhibitor building blocks 92
Forced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes 91
Increase of natural killer activity of mouse lymphocytes following in vitro and in vivo treatment with lithium. 90
Is It Time to Use Probiotics to Prevent or Treat Obesity? 89
LPS-conditioned dendritic cells confer endotoxin tolerance contingent on tryptophan catabolism 89
The TGF-β/IDO axis in infectious tolerance. 88
A retroviral peptide encoded by mutated env p15E gene is recognized by specific CD8+ T lymphocytes on drug-treated murine mastocytoma P815. 87
Dendritic cells expressing ectopic IL-35Ig induce IDO-related tolerance in vivo. 86
87P - Towards the identification of the mechanism of action of antitumor 1-methyl-D-tryptophan 86
Accelerated hematopoietic recovery and protective effect of the cyclooxygenase inhibitor indomethacin in bacterial infection of neutropenic mice. 85
Cutting edge: Autocrine TGF-beta sustains default tolerogenesis by IDO-competent dendritic cells. 84
Aryl hydrocarbon Receptor and RelB control long term expression of Indoleamine 2,3-dioxygenase-1 in endotoxin tolerance 84
Immunoregulatory interplay between arginine and tryptophan metabolism in health and disease 84
Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1 in juvenile diabetes 83
Neutralization of IL-10 up-regulates nitric oxide production and protects susceptible mice from challenge with Candida albicans. 82
The immunosuppressive activity of proinflammatory cytokines in experimental models: potential for therapeutic intervention in autoimmunity. 81
CD8+ cell activation to a major mastocytoma rejection antigen, P815AB: requirement for tum- or helper peptides in priming for skin test reactivity to a P815AB-related peptide 81
CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice 80
Preclinical discovery and development of fingolimod for the treatment of multiple sclerosis 80
A TLR9/TRIF pathway induces tolerance via TGF-beta and tryptophan catabolism in plasmacytoid dendritic cells 78
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells 78
A novel metabotropic glutamate receptor 4 allosteric modulator effective in multiple sclerosis experimental autoimmune encephalomyelitis (EAE) mouse model 78
88P - Relationship between functions and intracellular localization of the immune checkpoint target indoleamine 2, 3-dioxygenase 1 77
Xenograft of microencapsulated sertoli cells reverses T1DM in NOD mice by inducing neogenesis of beta-cells. 76
Immunogenic tumor variants induced by drug treatment of the L5178Y lymphoma: search for serologically defined antigens at the clonal level. 76
IL-12 acts selectively on CD8a- dendritic cells to enhance presentation of a tumor peptide in vivo 75
Cell-mediated immunity to chemically xenogenized tumors--IV. Production of lymphokine activity by, and in response to, highly immunogenic cells. 74
Different partners, opposite outcomes: A New Perspective of the Immunobiology of Indoleamine 2,3-Dioxygenase 74
Islet antigen-pulsed dendritic cells expressing ectopic IL-35Ig protect nonobese diabetic mice from autoimmune diabetes. 74
Autocrine IL-12 is involved in dendritic cell modulation via CD40 ligation 73
Bioengineering heterodimeric cytokines: turning promiscuous proteins into therapeutic agents. 73
Antigen-specific immunoregulation by IL-35Ig-transfected dendritic cells 73
Tracking Hidden Binding Pockets Along the Molecular Recognition Path of l-Trp to Indoleamine 2,3-Dioxygenase 1 71
Circulating levels of IL-10 are critically related to growth and rejection patterns of murine mastocytoma cells. 70
Modulation of tryptophan catabolism by regulatory T cells 69
Ectopic expression of IL-35Ig by dendritic cells induces tolerance via Arginase 1. 69
O6-alkylguanine-DNA alkyltransferase attenuates triazene-induced cytotoxicity and tumor cell immunogenicity in murine L1210 leukemia 68
Indoleamine 2,3-dioxygenase, transcriptional regulation and autoimmunity. 67
IL-6 inhibits the tolerogenic function of CD8 alpha+ dendritic cells expressing indoleamine 2,3-dioxygenase. 66
Dual effect of IL-4 on resistance to systemic gram-negative infection and production on TNF-alfa 66
High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway. 66
Interleukin-6 (IL-6) prevents activation-induced cell death (AICD): Interleukin-2-independent inhibition of Fas/FasL expression and cell death 65
Ligand Binding and Functional Selectivity ofl-Tryptophan Metabolites at the Mouse Aryl Hydrocarbon Receptor (mAhR) 65
Amino acid metabolism in rheumatoid arthritis: Friend or foe? 65
A novel mutation of indoleamine 2,3-dioxygenase 1 causes a rapid proteasomal degradation and compromises protein function 65
Evidence for tumor necrosis factor alpha as a mediator of the toxicity of a cyclooxygenase inhibitor in Gram-negative sepsis. 63
Cell-mediated immunity to chemically xenogenized tumors. V. Failure of novel antigens to increase the frequency of tumor-specific cytotoxic T cells. 63
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86. 62
EMBO workshop on immunology and metabolism 62
Dendritic cells, interleukin 12, and CD4+ lymphocytes in the initiation of class I-restricted reactivity to a tumor/self peptide. 61
Intrasplenic immunization for the induction of humoral and cell-mediated immunity to nitrocellulose-bound antigen. 59
Novel mutations in the WFS1 gene are associated with Wolfram syndrome and systemic inflammation 59
Cell-mediated immunity to chemically xenogenized tumors. I. Inhibition by specific antisera and H-2 association of the novel antigens. 58
New Insights from Crystallographic Data: Diversity of Structural Motifs and Molecular Recognition Properties between Groups of IDO1 Structures 58
Identification and immunogenic properties of an 80-kDa surface antigen on a drug-treated tumor variant: relationship to MuLV gp70. 57
Reinstalling immune regulatory tryptophan catabolism in juvenile diabetes via interleukin 6 receptor blockade 57
Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymes. 56
Tryptophan catabolism in IDO+ plasmacytoid dendritic cells 56
Cell-mediated immunity to chemically xenogenized tumors--III. Generation of monoclonal antibodies interfering with reactivity to novel antigens. 56
Induction of immunosuppressive functions and NF-kappa B by FLIP in monocytes 56
3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine 56
Multiple point mutations in an endogenous retroviral gene confer high immunogenicity on a drug-treated murine 55
A tumor-associated and self antigen peptide presented by dendritic cells may induce T cell anergy in vivo, but IL-12 can prevent or revert the anergic state 55
T cell apoptosis by tryptophan catabolism 55
Gamma interferon modifies CD4+ subset expression in murine candidiasis. 55
CTLA-4-immunoglobulin and indoleamine 2,3 dioxygenase in dominant tolerance. 55
T-cell subsets, IFN-gamma production and efferent specificity in anti-parental tumor immunity induced by mouse sensitization with xenogenized variant cells. 55
Course of primary candidiasis in T cell-depleted mice infected with attenuated variant cells. 55
Biotinylated Tryptophan Catabolites for Target Fishing. 55
Ectopic expression of IL-35Ig by dendritic cells induces IDO-related tolerance in vivo 55
IL-12 is both required and sufficient for initiating T-cell reactivity to a class I-restricted tumor peptide (P815AB) following transfer of P815AB-pulsed dendritic cells 55
The immune regulation in cancer by the amino acid metabolizing enzymes ARG and IDO 55
CD40 ligand and CTLA-4 are reciprocally regulated in the Th1 cell proliferative response sustained by CD8+ dendritic cells. 54
Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells. 53
Effects of IL-12 and IL-23 on antigen-presenting cells at the interface between innate and adaptive immunity. 53
Cell-mediated immunity to chemically xenogenized tumors. II. Evidence for accessory function and self-antigen presentation by a highly immunogenic tumor variant. 53
A general partnership between AhR and tryptophan catabolic enzymes and its role in endotoxin tolerance 53
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation 53
Effects of probiotic administration on immune responses of children and adolescents with type 1 diabetes to a quadrivalent inactivated influenza vaccine 53
Microscale thermophoresis and docking studies suggest lapachol and auraptene are ligands of IDO1 53
Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma 53
CTLA-4-Ig regulates tryptophan catabolism in vivo. 52
Towards the identification of a tolerogenic signature in IDO-competent dendritic cells 52
Cell-mediated immunity to chemically xenogenized tumors--VI. The effect of cell treatment with retroviral env antisense oligonucleotides. 52
Totale 7.551
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Categoria #
all - tutte 44.002
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 44.002
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020812 0 0 0 0 118 68 146 41 182 105 38 114
2020/20211.738 12 108 60 106 510 118 160 16 198 75 122 253
2021/20222.205 34 315 32 100 100 58 29 521 151 216 199 450
2022/20233.021 207 559 39 228 278 351 3 144 1.047 10 108 47
2023/20241.175 85 147 37 23 8 10 296 31 104 26 166 242
2024/2025873 37 225 141 151 319 0 0 0 0 0 0 0
Totale 11.109