IRIS - Res&Arch Institutional Research Information System - Research & Archive

GROHMANN, Ursula
 Distribuzione geografica
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Continente #
NA - Nord America 7.027
EU - Europa 5.474
AS - Asia 5.029
SA - Sud America 864
AF - Africa 128
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 7
Totale 18.539
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Nazione #
US - Stati Uniti d'America 6.876
SG - Singapore 2.428
IT - Italia 1.100
IE - Irlanda 793
CN - Cina 730
BR - Brasile 673
UA - Ucraina 673
HK - Hong Kong 606
RU - Federazione Russa 556
VN - Vietnam 547
SE - Svezia 515
DE - Germania 421
FR - Francia 365
RO - Romania 278
FI - Finlandia 252
GB - Regno Unito 158
IN - India 142
KR - Corea 109
CA - Canada 74
BD - Bangladesh 70
AR - Argentina 67
TR - Turchia 66
CZ - Repubblica Ceca 57
MX - Messico 50
BE - Belgio 49
IQ - Iraq 47
AT - Austria 44
PL - Polonia 43
JP - Giappone 40
NL - Olanda 40
PK - Pakistan 39
CO - Colombia 38
ZA - Sudafrica 35
CH - Svizzera 34
ID - Indonesia 33
EC - Ecuador 29
UZ - Uzbekistan 28
ES - Italia 27
GR - Grecia 22
CI - Costa d'Avorio 19
VE - Venezuela 19
PH - Filippine 17
SA - Arabia Saudita 17
LB - Libano 14
MA - Marocco 14
JO - Giordania 10
MY - Malesia 10
PE - Perù 10
PY - Paraguay 10
AZ - Azerbaigian 9
EU - Europa 9
KE - Kenya 9
LT - Lituania 9
TN - Tunisia 9
AE - Emirati Arabi Uniti 8
CL - Cile 8
ET - Etiopia 8
EG - Egitto 7
IL - Israele 7
PS - Palestinian Territory 7
TH - Thailandia 6
DZ - Algeria 5
GE - Georgia 5
OM - Oman 5
UY - Uruguay 5
AU - Australia 4
BG - Bulgaria 4
BO - Bolivia 4
KZ - Kazakistan 4
MD - Moldavia 4
NG - Nigeria 4
PA - Panama 4
PT - Portogallo 4
SN - Senegal 4
AL - Albania 3
DK - Danimarca 3
HN - Honduras 3
HR - Croazia 3
HU - Ungheria 3
JM - Giamaica 3
KW - Kuwait 3
MN - Mongolia 3
NI - Nicaragua 3
NP - Nepal 3
RS - Serbia 3
AM - Armenia 2
AO - Angola 2
CR - Costa Rica 2
EE - Estonia 2
GA - Gabon 2
GT - Guatemala 2
IR - Iran 2
KG - Kirghizistan 2
LC - Santa Lucia 2
LV - Lettonia 2
NZ - Nuova Zelanda 2
QA - Qatar 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
A2 - ???statistics.table.value.countryCode.A2??? 1
Totale 18.508
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Città #
Singapore 1.834
Chandler 861
Dublin 793
Hong Kong 601
Perugia 596
San Jose 508
San Mateo 440
Ashburn 357
Jacksonville 340
Boardman 300
Bucharest 272
Santa Clara 245
Dong Ket 226
Altamura 204
Wilmington 196
Medford 192
Moscow 191
Princeton 188
Beijing 186
Munich 157
Lauterbourg 156
Lawrence 153
Redmond 139
Ann Arbor 136
Des Moines 130
Andover 121
Los Angeles 114
Seoul 101
Ho Chi Minh City 100
Falls Church 92
New York 89
The Dalles 77
Hanoi 68
São Paulo 65
Turku 55
Saint Petersburg 51
Brussels 49
Dearborn 49
Orem 48
Helsinki 47
Norwalk 43
Woodbridge 43
Council Bluffs 40
Piscataway 39
Chennai 36
Chicago 36
Dallas 36
San Paolo di Civitate 35
Tokyo 33
Brno 32
Warsaw 31
Brooklyn 30
Houston 30
Frankfurt am Main 28
Nuremberg 28
Montreal 27
Pisa 26
Johannesburg 25
Izmir 24
Redwood City 23
Shanghai 23
London 22
Boston 21
Fremont 21
Olomouc 21
Columbus 20
Phoenix 20
Rio de Janeiro 20
Rome 20
Abidjan 19
Atlanta 19
Denver 19
Vienna 19
Baghdad 18
Haiphong 18
Manchester 17
Mumbai 17
Stockholm 17
Da Nang 15
Milan 15
Poplar 15
Tashkent 15
Amsterdam 14
Mexico City 14
Nanjing 14
San Francisco 14
Toronto 14
Lahore 13
Seattle 13
Ankara 12
Auburn Hills 12
Falkenstein 12
Guangzhou 12
Hefei 12
Belo Horizonte 11
Biên Hòa 11
Bogotá 11
Den Haag 11
Medellín 11
Ottawa 11
Totale 11.805
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Nome #
Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3-dioxygenase1 226
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1 211
A GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune Suppression. 202
Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells 202
Amino-acid sensing and degrading pathways in immune regulation 194
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells 191
Aryl hydrocarbon receptor control of a disease tolerance defence pathway. 190
Distinct roles of immunoreceptor tyrosine-based motifs in immunosuppressive indoleamine 2,3-dioxygenase 1. 181
Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells 181
Amino acid metabolism as drug target in autoimmune diseases 178
Advances in indoleamine 2,3-dioxygenase 1 medicinal chemistry 176
Identification of a 2-propanol analogue modulating the non-enzymatic function of indoleamine 2,3-dioxygenase 1 173
Accelerated hematopoietic recovery and protective effect of the cyclooxygenase inhibitor indomethacin in bacterial infection of neutropenic mice. 162
IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII 161
87P - Towards the identification of the mechanism of action of antitumor 1-methyl-D-tryptophan 156
Fragment-based approach to identify IDO1 inhibitor building blocks 152
IL‐35Ig–expressing dendritic cells induce tolerance via Arginase 1 151
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation 150
88P - Relationship between functions and intracellular localization of the immune checkpoint target indoleamine 2, 3-dioxygenase 1 150
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy 146
A retroviral peptide encoded by mutated env p15E gene is recognized by specific CD8+ T lymphocytes on drug-treated murine mastocytoma P815. 146
CD8+ cell activation to a major mastocytoma rejection antigen, P815AB: requirement for tum- or helper peptides in priming for skin test reactivity to a P815AB-related peptide 144
Is It Time to Use Probiotics to Prevent or Treat Obesity? 142
LPS-conditioned dendritic cells confer endotoxin tolerance contingent on tryptophan catabolism 142
Dendritic cells expressing ectopic IL-35Ig induce IDO-related tolerance in vivo. 141
A novel mutation of indoleamine 2,3-dioxygenase 1 causes a rapid proteasomal degradation and compromises protein function 141
Cutting edge: Autocrine TGF-beta sustains default tolerogenesis by IDO-competent dendritic cells. 139
3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine 139
T cell apoptosis by kynurenines. 137
The TGF-β/IDO axis in infectious tolerance. 134
Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1 in juvenile diabetes 134
Critical Assessment of a Structure-Based Screening Campaign for IDO1 Inhibitors: Tips and Pitfalls 131
Immunogenic tumor variants induced by drug treatment of the L5178Y lymphoma: search for serologically defined antigens at the clonal level. 130
Tracking Hidden Binding Pockets Along the Molecular Recognition Path of l-Trp to Indoleamine 2,3-Dioxygenase 1 130
Cell-mediated immunity to chemically xenogenized tumors--IV. Production of lymphokine activity by, and in response to, highly immunogenic cells. 129
Immunoregulatory interplay between arginine and tryptophan metabolism in health and disease 129
Increase of natural killer activity of mouse lymphocytes following in vitro and in vivo treatment with lithium. 128
Aryl hydrocarbon Receptor and RelB control long term expression of Indoleamine 2,3-dioxygenase-1 in endotoxin tolerance 127
A novel metabotropic glutamate receptor 4 allosteric modulator effective in multiple sclerosis experimental autoimmune encephalomyelitis (EAE) mouse model 126
A TLR9/TRIF pathway induces tolerance via TGF-beta and tryptophan catabolism in plasmacytoid dendritic cells 125
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86. 125
Antigen-specific immunoregulation by IL-35Ig-transfected dendritic cells 125
Forced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes 123
Circulating levels of IL-10 are critically related to growth and rejection patterns of murine mastocytoma cells. 122
New Insights from Crystallographic Data: Diversity of Structural Motifs and Molecular Recognition Properties between Groups of IDO1 Structures 122
Xenograft of microencapsulated sertoli cells reverses T1DM in NOD mice by inducing neogenesis of beta-cells. 121
Preclinical discovery and development of fingolimod for the treatment of multiple sclerosis 121
Dual effect of IL-4 on resistance to systemic gram-negative infection and production on TNF-alfa 120
Neutralization of IL-10 up-regulates nitric oxide production and protects susceptible mice from challenge with Candida albicans. 119
Ectopic expression of IL-35Ig by dendritic cells induces tolerance via Arginase 1. 119
Novel mutations in the WFS1 gene are associated with Wolfram syndrome and systemic inflammation 119
Different partners, opposite outcomes: A New Perspective of the Immunobiology of Indoleamine 2,3-Dioxygenase 118
CD40 ligation prevents onset of tolerogenic properties in human dendritic cells treated with CTLA-4-Ig. 117
Amino acid metabolism in rheumatoid arthritis: Friend or foe? 117
CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice 116
T-cell subsets, IFN-gamma production and efferent specificity in anti-parental tumor immunity induced by mouse sensitization with xenogenized variant cells. 116
Evidence for tumor necrosis factor alpha as a mediator of the toxicity of a cyclooxygenase inhibitor in Gram-negative sepsis. 116
Tryptophan catabolism in IDO+ plasmacytoid dendritic cells 115
Islet antigen-pulsed dendritic cells expressing ectopic IL-35Ig protect nonobese diabetic mice from autoimmune diabetes. 114
Effects of probiotic administration on immune responses of children and adolescents with type 1 diabetes to a quadrivalent inactivated influenza vaccine 114
Microscale thermophoresis and docking studies suggest lapachol and auraptene are ligands of IDO1 113
The immunosuppressive activity of proinflammatory cytokines in experimental models: potential for therapeutic intervention in autoimmunity. 112
IL-12 acts selectively on CD8a- dendritic cells to enhance presentation of a tumor peptide in vivo 112
Autocrine IL-12 is involved in dendritic cell modulation via CD40 ligation 111
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells 110
CD40 ligand and CTLA-4 are reciprocally regulated in the Th1 cell proliferative response sustained by CD8+ dendritic cells. 107
Cell-mediated immunity to chemically xenogenized tumors. I. Inhibition by specific antisera and H-2 association of the novel antigens. 107
A tumor-associated and self antigen peptide presented by dendritic cells may induce T cell anergy in vivo, but IL-12 can prevent or revert the anergic state 105
Interleukin-6 (IL-6) prevents activation-induced cell death (AICD): Interleukin-2-independent inhibition of Fas/FasL expression and cell death 105
O6-alkylguanine-DNA alkyltransferase attenuates triazene-induced cytotoxicity and tumor cell immunogenicity in murine L1210 leukemia 105
Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma 104
Dendritic cells, interleukin 12, and CD4+ lymphocytes in the initiation of class I-restricted reactivity to a tumor/self peptide. 102
Modulation of tryptophan catabolism by regulatory T cells 101
Ligand Binding and Functional Selectivity ofl-Tryptophan Metabolites at the Mouse Aryl Hydrocarbon Receptor (mAhR) 101
Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymes. 100
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease 100
A general partnership between AhR and tryptophan catabolic enzymes and its role in endotoxin tolerance 98
CD40 ligation ablates the tolerogenic potential of lymphoid dendritic cells 98
Reinstalling immune regulatory tryptophan catabolism in juvenile diabetes via interleukin 6 receptor blockade 97
Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12 97
Multiple point mutations in an endogenous retroviral gene confer high immunogenicity on a drug-treated murine 96
IL-6 inhibits the tolerogenic function of CD8 alpha+ dendritic cells expressing indoleamine 2,3-dioxygenase. 96
Course of primary candidiasis in T cell-depleted mice infected with attenuated variant cells. 96
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice 96
High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway. 96
Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells. 95
Loss of IDO1 Expression From Human Pancreatic -Cells Precedes Their Destruction During the Development of Type 1 Diabetes 94
Induction of immunosuppressive functions and NF-kappa B by FLIP in monocytes 94
Indoleamine 2,3-dioxygenase, transcriptional regulation and autoimmunity. 93
Towards the identification of a tolerogenic signature in IDO-competent dendritic cells 93
CTLA-4-immunoglobulin and indoleamine 2,3 dioxygenase in dominant tolerance. 93
Bioengineering heterodimeric cytokines: turning promiscuous proteins into therapeutic agents. 93
Cutting edge: silencing suppressor of cytokine signaling 3 expression in dendritic cells turns CD28-Ig from immune adjuvant to suppressant. 93
CTLA-4-Ig regulates tryptophan catabolism in vivo. 92
T cell apoptosis by tryptophan catabolism 92
Cell-mediated immunity to chemically xenogenized tumors--III. Generation of monoclonal antibodies interfering with reactivity to novel antigens. 92
IL-9 protects mice from Fram-negative bacterial shock: suppression of alfa-TNF, IL-12 and gamma-IFN, and induction of IL-10. 91
Gamma interferon modifies CD4+ subset expression in murine candidiasis. 91
Ectopic expression of IL-35Ig by dendritic cells induces IDO-related tolerance in vivo 91
Pathogenetic Interplay Between IL-6 and Tryptophan Metabolism in an Experimental Model of Obesity 91
Totale 12.559
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Categoria #
all - tutte 76.377
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 76.377
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021450 0 0 0 0 0 0 0 0 0 75 122 253
2021/20222.205 34 315 32 100 100 58 29 521 151 216 199 450
2022/20233.021 207 559 39 228 278 351 3 144 1.047 10 108 47
2023/20241.175 85 147 37 23 8 10 296 31 104 26 166 242
2024/20252.687 37 225 141 151 327 144 113 190 508 157 422 272
2025/20266.183 394 438 378 859 823 618 1.117 396 663 497 0 0
Totale 19.106