IRIS - Res&Arch Institutional Research Information System - Research & Archive

GROHMANN, Ursula
 Distribuzione geografica
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Continente #
NA - Nord America 7.436
EU - Europa 5.523
AS - Asia 5.087
SA - Sud America 872
Continente sconosciuto - Info sul continente non disponibili 577
AF - Africa 131
OC - Oceania 7
Totale 19.633
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Nazione #
US - Stati Uniti d'America 7.236
SG - Singapore 2.447
IT - Italia 1.136
IE - Irlanda 793
CN - Cina 756
BR - Brasile 678
UA - Ucraina 673
HK - Hong Kong 610
RU - Federazione Russa 556
VN - Vietnam 547
SE - Svezia 515
DE - Germania 423
FR - Francia 367
RO - Romania 278
FI - Finlandia 252
GB - Regno Unito 158
IN - India 142
KR - Corea 109
CA - Canada 99
BD - Bangladesh 75
AR - Argentina 68
TR - Turchia 66
CZ - Repubblica Ceca 57
MX - Messico 51
BE - Belgio 49
IQ - Iraq 47
AT - Austria 44
PL - Polonia 43
NL - Olanda 42
JP - Giappone 40
PK - Pakistan 39
CO - Colombia 38
ZA - Sudafrica 36
CH - Svizzera 34
ID - Indonesia 34
EC - Ecuador 29
ES - Italia 29
UZ - Uzbekistan 28
GR - Grecia 22
VE - Venezuela 20
CI - Costa d'Avorio 19
PH - Filippine 18
SA - Arabia Saudita 17
LB - Libano 14
MA - Marocco 14
JM - Giamaica 12
JO - Giordania 10
LT - Lituania 10
MY - Malesia 10
PE - Perù 10
PY - Paraguay 10
AZ - Azerbaigian 9
CL - Cile 9
EU - Europa 9
KE - Kenya 9
TN - Tunisia 9
AE - Emirati Arabi Uniti 8
ET - Etiopia 8
EG - Egitto 7
IL - Israele 7
PS - Palestinian Territory 7
CR - Costa Rica 6
TH - Thailandia 6
DZ - Algeria 5
GE - Georgia 5
NI - Nicaragua 5
OM - Oman 5
PT - Portogallo 5
UY - Uruguay 5
AU - Australia 4
BG - Bulgaria 4
BO - Bolivia 4
GT - Guatemala 4
HU - Ungheria 4
IR - Iran 4
KZ - Kazakistan 4
MD - Moldavia 4
NG - Nigeria 4
PA - Panama 4
SN - Senegal 4
AL - Albania 3
DK - Danimarca 3
HN - Honduras 3
HR - Croazia 3
KW - Kuwait 3
LC - Santa Lucia 3
LV - Lettonia 3
MN - Mongolia 3
NP - Nepal 3
RS - Serbia 3
AM - Armenia 2
AO - Angola 2
BZ - Belize 2
EE - Estonia 2
GA - Gabon 2
KG - Kirghizistan 2
NZ - Nuova Zelanda 2
QA - Qatar 2
SC - Seychelles 2
SI - Slovenia 2
Totale 19.028
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Città #
Singapore 1.840
Chandler 861
Dublin 793
Hong Kong 605
Perugia 598
San Jose 539
San Mateo 440
Ashburn 386
Jacksonville 343
Boardman 301
Bucharest 272
Santa Clara 257
Dong Ket 226
Altamura 204
Beijing 197
Wilmington 197
Medford 192
Moscow 191
Princeton 188
Munich 157
Lauterbourg 156
Lawrence 153
Redmond 139
Ann Arbor 136
Des Moines 130
Los Angeles 127
Andover 121
Seoul 101
Ho Chi Minh City 100
New York 99
Falls Church 92
The Dalles 79
Hanoi 68
São Paulo 68
Turku 55
Orem 52
Saint Petersburg 51
Brussels 49
Dearborn 49
Helsinki 47
Dallas 44
Norwalk 43
Piscataway 43
Woodbridge 43
Chicago 42
Council Bluffs 41
Chennai 36
Houston 35
San Paolo di Civitate 35
Montreal 34
Tokyo 33
Brno 32
Warsaw 31
Brooklyn 30
Frankfurt am Main 28
Nuremberg 28
Phoenix 28
Pisa 26
Johannesburg 25
Izmir 24
Shanghai 24
Atlanta 23
Boston 23
Redwood City 23
Fremont 22
London 22
Rome 22
Columbus 21
Milan 21
Olomouc 21
Denver 20
Rio de Janeiro 20
Abidjan 19
Vienna 19
Baghdad 18
Haiphong 18
Toronto 18
Manchester 17
Mumbai 17
Stockholm 17
Da Nang 15
Poplar 15
Tashkent 15
Amsterdam 14
Mexico City 14
Nanjing 14
San Francisco 14
Lahore 13
Seattle 13
Ankara 12
Auburn Hills 12
Falkenstein 12
Guangzhou 12
Hefei 12
Belo Horizonte 11
Biên Hòa 11
Bogotá 11
Den Haag 11
Medellín 11
Ottawa 11
Totale 11.998
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Nome #
Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3-dioxygenase1 228
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1 212
A GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune Suppression. 207
Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells 204
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells 201
Amino-acid sensing and degrading pathways in immune regulation 197
Aryl hydrocarbon receptor control of a disease tolerance defence pathway. 190
Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells 186
Distinct roles of immunoreceptor tyrosine-based motifs in immunosuppressive indoleamine 2,3-dioxygenase 1. 183
Advances in indoleamine 2,3-dioxygenase 1 medicinal chemistry 182
Amino acid metabolism as drug target in autoimmune diseases 180
Identification of a 2-propanol analogue modulating the non-enzymatic function of indoleamine 2,3-dioxygenase 1 175
Accelerated hematopoietic recovery and protective effect of the cyclooxygenase inhibitor indomethacin in bacterial infection of neutropenic mice. 162
IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII 161
87P - Towards the identification of the mechanism of action of antitumor 1-methyl-D-tryptophan 161
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation 160
Fragment-based approach to identify IDO1 inhibitor building blocks 157
IL‐35Ig–expressing dendritic cells induce tolerance via Arginase 1 157
88P - Relationship between functions and intracellular localization of the immune checkpoint target indoleamine 2, 3-dioxygenase 1 152
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy 149
A retroviral peptide encoded by mutated env p15E gene is recognized by specific CD8+ T lymphocytes on drug-treated murine mastocytoma P815. 149
CD8+ cell activation to a major mastocytoma rejection antigen, P815AB: requirement for tum- or helper peptides in priming for skin test reactivity to a P815AB-related peptide 147
Is It Time to Use Probiotics to Prevent or Treat Obesity? 147
LPS-conditioned dendritic cells confer endotoxin tolerance contingent on tryptophan catabolism 146
Dendritic cells expressing ectopic IL-35Ig induce IDO-related tolerance in vivo. 145
A novel mutation of indoleamine 2,3-dioxygenase 1 causes a rapid proteasomal degradation and compromises protein function 145
3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine 145
Cutting edge: Autocrine TGF-beta sustains default tolerogenesis by IDO-competent dendritic cells. 143
Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1 in juvenile diabetes 140
T cell apoptosis by kynurenines. 138
The TGF-β/IDO axis in infectious tolerance. 137
Critical Assessment of a Structure-Based Screening Campaign for IDO1 Inhibitors: Tips and Pitfalls 137
Immunoregulatory interplay between arginine and tryptophan metabolism in health and disease 136
Tracking Hidden Binding Pockets Along the Molecular Recognition Path of l-Trp to Indoleamine 2,3-Dioxygenase 1 135
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86. 131
Immunogenic tumor variants induced by drug treatment of the L5178Y lymphoma: search for serologically defined antigens at the clonal level. 131
Cell-mediated immunity to chemically xenogenized tumors--IV. Production of lymphokine activity by, and in response to, highly immunogenic cells. 130
A TLR9/TRIF pathway induces tolerance via TGF-beta and tryptophan catabolism in plasmacytoid dendritic cells 129
Increase of natural killer activity of mouse lymphocytes following in vitro and in vivo treatment with lithium. 129
A novel metabotropic glutamate receptor 4 allosteric modulator effective in multiple sclerosis experimental autoimmune encephalomyelitis (EAE) mouse model 129
Aryl hydrocarbon Receptor and RelB control long term expression of Indoleamine 2,3-dioxygenase-1 in endotoxin tolerance 129
Antigen-specific immunoregulation by IL-35Ig-transfected dendritic cells 128
New Insights from Crystallographic Data: Diversity of Structural Motifs and Molecular Recognition Properties between Groups of IDO1 Structures 128
Ectopic expression of IL-35Ig by dendritic cells induces tolerance via Arginase 1. 125
Circulating levels of IL-10 are critically related to growth and rejection patterns of murine mastocytoma cells. 124
Xenograft of microencapsulated sertoli cells reverses T1DM in NOD mice by inducing neogenesis of beta-cells. 124
Forced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetes 124
Novel mutations in the WFS1 gene are associated with Wolfram syndrome and systemic inflammation 123
Dual effect of IL-4 on resistance to systemic gram-negative infection and production on TNF-alfa 122
Preclinical discovery and development of fingolimod for the treatment of multiple sclerosis 122
Neutralization of IL-10 up-regulates nitric oxide production and protects susceptible mice from challenge with Candida albicans. 120
T-cell subsets, IFN-gamma production and efferent specificity in anti-parental tumor immunity induced by mouse sensitization with xenogenized variant cells. 120
Evidence for tumor necrosis factor alpha as a mediator of the toxicity of a cyclooxygenase inhibitor in Gram-negative sepsis. 120
CD40 ligation prevents onset of tolerogenic properties in human dendritic cells treated with CTLA-4-Ig. 120
Different partners, opposite outcomes: A New Perspective of the Immunobiology of Indoleamine 2,3-Dioxygenase 118
Amino acid metabolism in rheumatoid arthritis: Friend or foe? 118
CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice 117
Tryptophan catabolism in IDO+ plasmacytoid dendritic cells 117
The immunosuppressive activity of proinflammatory cytokines in experimental models: potential for therapeutic intervention in autoimmunity. 116
Islet antigen-pulsed dendritic cells expressing ectopic IL-35Ig protect nonobese diabetic mice from autoimmune diabetes. 116
Microscale thermophoresis and docking studies suggest lapachol and auraptene are ligands of IDO1 116
IL-12 acts selectively on CD8a- dendritic cells to enhance presentation of a tumor peptide in vivo 115
Effects of probiotic administration on immune responses of children and adolescents with type 1 diabetes to a quadrivalent inactivated influenza vaccine 115
Autocrine IL-12 is involved in dendritic cell modulation via CD40 ligation 114
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells 112
A tumor-associated and self antigen peptide presented by dendritic cells may induce T cell anergy in vivo, but IL-12 can prevent or revert the anergic state 110
CD40 ligand and CTLA-4 are reciprocally regulated in the Th1 cell proliferative response sustained by CD8+ dendritic cells. 109
Cell-mediated immunity to chemically xenogenized tumors. I. Inhibition by specific antisera and H-2 association of the novel antigens. 109
Interleukin-6 (IL-6) prevents activation-induced cell death (AICD): Interleukin-2-independent inhibition of Fas/FasL expression and cell death 106
O6-alkylguanine-DNA alkyltransferase attenuates triazene-induced cytotoxicity and tumor cell immunogenicity in murine L1210 leukemia 106
Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma 106
Dendritic cells, interleukin 12, and CD4+ lymphocytes in the initiation of class I-restricted reactivity to a tumor/self peptide. 105
Pathogenetic Interplay Between IL-6 and Tryptophan Metabolism in an Experimental Model of Obesity 105
Modulation of tryptophan catabolism by regulatory T cells 104
Ligand Binding and Functional Selectivity ofl-Tryptophan Metabolites at the Mouse Aryl Hydrocarbon Receptor (mAhR) 103
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease 102
Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymes. 101
A general partnership between AhR and tryptophan catabolic enzymes and its role in endotoxin tolerance 100
Reinstalling immune regulatory tryptophan catabolism in juvenile diabetes via interleukin 6 receptor blockade 100
CD40 ligation ablates the tolerogenic potential of lymphoid dendritic cells 100
High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway. 99
Multiple point mutations in an endogenous retroviral gene confer high immunogenicity on a drug-treated murine 98
IL-6 inhibits the tolerogenic function of CD8 alpha+ dendritic cells expressing indoleamine 2,3-dioxygenase. 98
Course of primary candidiasis in T cell-depleted mice infected with attenuated variant cells. 98
Cutting edge: silencing suppressor of cytokine signaling 3 expression in dendritic cells turns CD28-Ig from immune adjuvant to suppressant. 98
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice 98
T cell apoptosis by tryptophan catabolism 97
Towards the identification of a tolerogenic signature in IDO-competent dendritic cells 97
Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12 97
CTLA-4-Ig regulates tryptophan catabolism in vivo. 96
Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells. 96
CTLA-4-immunoglobulin and indoleamine 2,3 dioxygenase in dominant tolerance. 96
Cell-mediated immunity to chemically xenogenized tumors--III. Generation of monoclonal antibodies interfering with reactivity to novel antigens. 96
Bioengineering heterodimeric cytokines: turning promiscuous proteins into therapeutic agents. 96
Loss of IDO1 Expression From Human Pancreatic -Cells Precedes Their Destruction During the Development of Type 1 Diabetes 96
Indoleamine 2,3-dioxygenase, transcriptional regulation and autoimmunity. 95
Gamma interferon modifies CD4+ subset expression in murine candidiasis. 95
Induction of immunosuppressive functions and NF-kappa B by FLIP in monocytes 95
Positive regulatory role of IL-12 in macrophages and modulation by IFN-gamma 94
The landscape of AhR regulators and coregulators to fine-tune AhR functions 94
Totale 12.871
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Categoria #
all - tutte 84.525
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 84.525
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.171 0 315 32 100 100 58 29 521 151 216 199 450
2022/20233.021 207 559 39 228 278 351 3 144 1.047 10 108 47
2023/20241.175 85 147 37 23 8 10 296 31 104 26 166 242
2024/20252.687 37 225 141 151 327 144 113 190 508 157 422 272
2025/20266.410 394 438 378 859 823 618 1.117 396 663 524 137 63
2026/2027300 130 170 0 0 0 0 0 0 0 0 0 0
Totale 19.633